PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells

Journal of Immunology

Volumn 194, Issue 12, 2015, Pages 5801-5811

  Park, Hyo Jin ^a   Park, Joon Seok ^a,g   Jeong, Yun Hee ^a   Son, Jimin ^a   Ban, Young Ho ^a   Lee, Byoung Hee ^b   Chen, Lieping ^c   Chang, Jun ^d   Chung, Doo Hyun ^e   Choi, Inhak ^f   Ha, Sang Jun ^a  

^a Yonsei University   (South Korea)

^b National Institute of Biological Resources   (South Korea)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Ewha Womans University   (South Korea)

^e Seoul National University   (South Korea)

^f Inje University   (South Korea)

^g ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; ALPHA E INTEGRINS; ALPHA INTEGRIN; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; LEUKOCYTE ANTIGEN;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CONTACT; CELL EXPANSION; CHRONIC DISEASE; CHRONIC VIRAL INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; UPREGULATION; VIRUS INFECTION; ANIMAL; CELL COMMUNICATION; DISEASE MODEL; GENE EXPRESSION; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; IMMUNOPHENOTYPING; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; METABOLISM; PHENOTYPE; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD274; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN; IMMUNOMODULATION; IMMUNOPHENOTYPING; INTEGRIN ALPHA CHAINS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; MICE; MICE, KNOCKOUT; PHENOTYPE; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; VIRUS DISEASES;

EID: 84931406088     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401936     Document Type: Article

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