Inositol-requiring enzyme 1-mediated endoplasmic reticulum stress triggers apoptosis and fibrosis formation in liver cirrhosis rat models

Molecular Medicine Reports

Volumn 11, Issue 4, 2015, Pages 2941-2946

  Jiang, Tianpeng ^a   Wang, Lizhou ^a   Li, Xing ^a   Song, Jie ^a   Wu, Xiaoping ^a   Zhou, Shi ^a  

^a GUIZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; CHOP; ER stress; IRE1; Liver cirrhosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CASPASE 12; CELL ENZYME; DESMIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INOSITOL REQUIRING ENZYME 1; MESSENGER RNA; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 6; IRE1ALPHA PROTEIN, RAT; MULTIENZYME COMPLEX; PERK KINASE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FIBROGENESIS; FLOW CYTOMETRY; LIVER CIRRHOSIS; LIVER FIBROSIS; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; ANIMAL; FIBROSIS; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

RATTUS;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FIBROSIS; LIVER CIRRHOSIS; MULTIENZYME COMPLEXES; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP; UNFOLDED PROTEIN RESPONSE;

EID: 84921324811     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.3020     Document Type: Article

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