Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway

Toxicological Sciences

Volumn 144, Issue 2, 2015, Pages 328-337

  Boussabbeh, Manel ^a   Salem, Intidhar Ben ^a   Prola, Alexandre ^b   Guilbert, Arnaud ^b   Bacha, Hassen ^a   Abid Essefi, Salwa ^a   Lemaire, Christophe ^b,c,d  

^a Faculty of Dentistry   (Tunisia)

^b INSERM   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Oxidative stress; Patulin

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; GADD34 PROTEIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PATULIN; PROTEIN; PROTEIN BAK; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; COLON CARCINOMA; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FLOW CYTOMETRY; HCT116 CELL LINE; HEK293 CELL LINE; HUMAN; HUMAN CELL; IC50; KIDNEY CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WESTERN BLOTTING; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE;

ASPERGILLUS; BYSSOCHLAMYS; FUNGI; MALUS X DOMESTICA; PENICILLIUM;

ACETYLCYSTEINE; APOPTOSIS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; HUMANS; OXIDATIVE STRESS; PATULIN; REACTIVE OXYGEN SPECIES;

EID: 84926484919     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu319     Document Type: Article

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