-
1
-
-
34548027000
-
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
-
Joshi, N. S., W. Cui, A. Chandele, H. K. Lee, D. R. Urso, J. Hagman, L. Gapin, and S. M. Kaech. 2007. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27: 281-295.
-
(2007)
Immunity
, vol.27
, pp. 281-295
-
-
Joshi, N.S.1
Cui, W.2
Chandele, A.3
Lee, H.K.4
Urso, D.R.5
Hagman, J.6
Gapin, L.7
Kaech, S.M.8
-
2
-
-
41149099559
-
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
-
Sarkar, S., V. Kalia, W. N. Haining, B. T. Konieczny, S. Subramaniam, and R. Ahmed. 2008. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J. Exp. Med. 205: 625-640.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 625-640
-
-
Sarkar, S.1
Kalia, V.2
Haining, W.N.3
Konieczny, B.T.4
Subramaniam, S.5
Ahmed, R.6
-
3
-
-
74549162832
-
Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
-
Kalia, V., S. Sarkar, S. Subramaniam, W. N. Haining, K. A. Smith, and R. Ahmed. 2010. Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 32: 91-103.
-
(2010)
Immunity
, vol.32
, pp. 91-103
-
-
Kalia, V.1
Sarkar, S.2
Subramaniam, S.3
Haining, W.N.4
Smith, K.A.5
Ahmed, R.6
-
4
-
-
84905986225
-
IL-2 induction of Blimp-1 is a key in vivo signal for CD8+ short-lived effector T cell differentiation
-
Boulet, S., J. F. Daudelin, and N. Labrecque. 2014. IL-2 induction of Blimp-1 is a key in vivo signal for CD8+ short-lived effector T cell differentiation. J. Immunol. 193: 1847-1854.
-
(2014)
J. Immunol.
, vol.193
, pp. 1847-1854
-
-
Boulet, S.1
Daudelin, J.F.2
Labrecque, N.3
-
5
-
-
68649111205
-
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties
-
Rutishauser, R. L., G. A. Martins, S. Kalachikov, A. Chandele, I. A. Parish, E. Meffre, J. Jacob, K. Calame, and S. M. Kaech. 2009. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity 31: 296-308.
-
(2009)
Immunity
, vol.31
, pp. 296-308
-
-
Rutishauser, R.L.1
Martins, G.A.2
Kalachikov, S.3
Chandele, A.4
Parish, I.A.5
Meffre, E.6
Jacob, J.7
Calame, K.8
Kaech, S.M.9
-
6
-
-
68649092345
-
Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses
-
Kallies, A., A. Xin, G. T. Belz, and S. L. Nutt. 2009. Blimp-1 transcription factor is required for the differentiation of effector CD8(+) T cells and memory responses. Immunity 31: 283-295.
-
(2009)
Immunity
, vol.31
, pp. 283-295
-
-
Kallies, A.1
Xin, A.2
Belz, G.T.3
Nutt, S.L.4
-
7
-
-
33845894709
-
Notch signalling during peripheral T-cell activation and differentiation
-
Osborne, B. A., and L. M. Minter. 2007. Notch signalling during peripheral T-cell activation and differentiation. Nat. Rev. Immunol. 7: 64-75.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 64-75
-
-
Osborne, B.A.1
Minter, L.M.2
-
8
-
-
33845306813
-
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
-
Palomero, T., W. K. Lim, D. T. Odom, M. L. Sulis, P. J. Real, A. Margolin, K. C. Barnes, J. O'Neil, D. Neuberg, A. P. Weng, et al. 2006. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. Proc. Natl. Acad. Sci. USA 103: 18261-18266.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18261-18266
-
-
Palomero, T.1
Lim, W.K.2
Odom, D.T.3
Sulis, M.L.4
Real, P.J.5
Margolin, A.6
Barnes, K.C.7
O'Neil, J.8
Neuberg, D.9
Weng, A.P.10
-
9
-
-
33746546368
-
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/ lymphoma
-
Weng, A. P., J. M. Millholland, Y. Yashiro-Ohtani, M. L. Arcangeli, A. Lau, C. Wai, C. Del Bianco, C. G. Rodriguez, H. Sai, J. Tobias, et al. 2006. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/ lymphoma. Genes Dev. 20: 2096-2109.
-
(2006)
Genes Dev.
, vol.20
, pp. 2096-2109
-
-
Weng, A.P.1
Millholland, J.M.2
Yashiro-Ohtani, Y.3
Arcangeli, M.L.4
Lau, A.5
Wai, C.6
Del Bianco, C.7
Rodriguez, C.G.8
Sai, H.9
Tobias, J.10
-
10
-
-
84897129801
-
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells
-
Geimer Le Lay, A. S., A. Oravecz, J. Mastio, C. Jung, P. Marchal, C. Ebel, D. Dembélé, B. Jost, S. Le Gras, C. Thibault, et al. 2014. The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells. Sci. Signal. 7: ra28.
-
(2014)
Sci. Signal.
, vol.7
, pp. ra28
-
-
Geimer Le Lay, A.S.1
Oravecz, A.2
Mastio, J.3
Jung, C.4
Marchal, P.5
Ebel, C.6
Dembélé, D.7
Jost, B.8
Le Gras, S.9
Thibault, C.10
-
11
-
-
84892622973
-
NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
-
Wang, H., C. Zang, L. Taing, K. L. Arnett, Y. J. Wong, W. S. Pear, S. C. Blacklow, X. S. Liu, and J. C. Aster. 2014. NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. Proc. Natl. Acad. Sci. USA 111: 705-710.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 705-710
-
-
Wang, H.1
Zang, C.2
Taing, L.3
Arnett, K.L.4
Wong, Y.J.5
Pear, W.S.6
Blacklow, S.C.7
Liu, X.S.8
Aster, J.C.9
-
13
-
-
2342496710
-
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
-
Amsen, D., J. M. Blander, G. R. Lee, K. Tanigaki, T. Honjo, and R. A. Flavell. 2004. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 117: 515-526.
-
(2004)
Cell
, vol.117
, pp. 515-526
-
-
Amsen, D.1
Blander, J.M.2
Lee, G.R.3
Tanigaki, K.4
Honjo, T.5
Flavell, R.A.6
-
14
-
-
22144492615
-
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
-
Minter, L. M., D. M. Turley, P. Das, H. M. Shin, I. Joshi, R. G. Lawlor, O. H. Cho, T. Palaga, S. Gottipati, J. C. Telfer, et al. 2005. Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat. Immunol. 6: 680-688.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 680-688
-
-
Minter, L.M.1
Turley, D.M.2
Das, P.3
Shin, H.M.4
Joshi, I.5
Lawlor, R.G.6
Cho, O.H.7
Palaga, T.8
Gottipati, S.9
Telfer, J.C.10
-
15
-
-
84880848750
-
Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia
-
Roderick, J. E., G. Gonzalez-Perez, C. A. Kuksin, A. Dongre, E. R. Roberts, J. Srinivasan, C. Andrzejewski, Jr., A. H. Fauq, T. E. Golde, L. Miele, and L. M. Minter. 2013. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia. J. Exp. Med. 210: 1311-1329.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1311-1329
-
-
Roderick, J.E.1
Gonzalez-Perez, G.2
Kuksin, C.A.3
Dongre, A.4
Roberts, E.R.5
Srinivasan, J.6
Andrzejewski, C.7
Fauq, A.H.8
Golde, T.E.9
Miele, L.10
Minter, L.M.11
-
16
-
-
34447634411
-
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
-
Amsen, D., A. Antov, D. Jankovic, A. Sher, F. Radtke, A. Souabni, M. Busslinger, B. McCright, T. Gridley, and R. A. Flavell. 2007. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27: 89-99.
-
(2007)
Immunity
, vol.27
, pp. 89-99
-
-
Amsen, D.1
Antov, A.2
Jankovic, D.3
Sher, A.4
Radtke, F.5
Souabni, A.6
Busslinger, M.7
McCright, B.8
Gridley, T.9
Flavell, R.A.10
-
17
-
-
34447642439
-
Notch directly regulates Gata3 expression during T helper 2 cell differentiation
-
Fang, T. C., Y. Yashiro-Ohtani, C. Del Bianco, D. M. Knoblock, S. C. Blacklow, and W. S. Pear. 2007. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 27: 100-110.
-
(2007)
Immunity
, vol.27
, pp. 100-110
-
-
Fang, T.C.1
Yashiro-Ohtani, Y.2
Del Bianco, C.3
Knoblock, D.M.4
Blacklow, S.C.5
Pear, W.S.6
-
18
-
-
67649216137
-
Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation
-
Mukherjee, S., M. A. Schaller, R. Neupane, S. L. Kunkel, and N. W. Lukacs. 2009. Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation. J. Immunol. 182: 7381-7388.
-
(2009)
J. Immunol.
, vol.182
, pp. 7381-7388
-
-
Mukherjee, S.1
Schaller, M.A.2
Neupane, R.3
Kunkel, S.L.4
Lukacs, N.W.5
-
19
-
-
84859997488
-
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells
-
Elyaman, W., R. Bassil, E. M. Bradshaw, W. Orent, Y. Lahoud, B. Zhu, F. Radtke, H. Yagita, and S. J. Khoury. 2012. Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity 36: 623-634.
-
(2012)
Immunity
, vol.36
, pp. 623-634
-
-
Elyaman, W.1
Bassil, R.2
Bradshaw, E.M.3
Orent, W.4
Lahoud, Y.5
Zhu, B.6
Radtke, F.7
Yagita, H.8
Khoury, S.J.9
-
20
-
-
10744222828
-
Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes
-
Anastasi, E., A. F. Campese, D. Bellavia, A. Bulotta, A. Balestri, M. Pascucci, S. Checquolo, R. Gradini, U. Lendahl, L. Frati, et al. 2003. Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes. J. Immunol. 171: 4504-4511.
-
(2003)
J. Immunol.
, vol.171
, pp. 4504-4511
-
-
Anastasi, E.1
Campese, A.F.2
Bellavia, D.3
Bulotta, A.4
Balestri, A.5
Pascucci, M.6
Checquolo, S.7
Gradini, R.8
Lendahl, U.9
Frati, L.10
-
21
-
-
84880729295
-
Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals
-
Bailis, W., Y. Yashiro-Ohtani, T. C. Fang, R. D. Hatton, C. T. Weaver, D. Artis, and W. S. Pear. 2013. Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals. Immunity 39: 148-159.
-
(2013)
Immunity
, vol.39
, pp. 148-159
-
-
Bailis, W.1
Yashiro-Ohtani, Y.2
Fang, T.C.3
Hatton, R.D.4
Weaver, C.T.5
Artis, D.6
Pear, W.S.7
-
22
-
-
0041331708
-
TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells
-
Palaga, T., L. Miele, T. E. Golde, and B. A. Osborne. 2003. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J. Immunol. 171: 3019-3024.
-
(2003)
J. Immunol.
, vol.171
, pp. 3019-3024
-
-
Palaga, T.1
Miele, L.2
Golde, T.E.3
Osborne, B.A.4
-
23
-
-
65449183749
-
Notch regulates cytolytic effector function in CD8+ T cells
-
Cho, O. H., H. M. Shin, L. Miele, T. E. Golde, A. Fauq, L. M. Minter, and B. A. Osborne. 2009. Notch regulates cytolytic effector function in CD8+ T cells. J. Immunol. 182: 3380-3389.
-
(2009)
J. Immunol.
, vol.182
, pp. 3380-3389
-
-
Cho, O.H.1
Shin, H.M.2
Miele, L.3
Golde, T.E.4
Fauq, A.5
Minter, L.M.6
Osborne, B.A.7
-
24
-
-
52549130987
-
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
-
Maekawa, Y., Y. Minato, C. Ishifune, T. Kurihara, A. Kitamura, H. Kojima, H. Yagita, M. Sakata-Yanagimoto, T. Saito, I. Taniuchi, et al. 2008. Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat. Immunol. 9: 1140-1147.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1140-1147
-
-
Maekawa, Y.1
Minato, Y.2
Ishifune, C.3
Kurihara, T.4
Kitamura, A.5
Kojima, H.6
Yagita, H.7
Sakata-Yanagimoto, M.8
Saito, T.9
Taniuchi, I.10
-
25
-
-
84878264534
-
Notch controls generation and function of human effector CD8+ T cells
-
Kuijk, L. M., M. I. Verstege, N. V. Rekers, S. C. Bruijns, E. Hooijberg, B. O. Roep, T. D. de Gruijl, Y. van Kooyk, and W. W. Unger. 2013. Notch controls generation and function of human effector CD8+ T cells. Blood 121: 2638-2646.
-
(2013)
Blood
, vol.121
, pp. 2638-2646
-
-
Kuijk, L.M.1
Verstege, M.I.2
Rekers, N.V.3
Bruijns, S.C.4
Hooijberg, E.5
Roep, B.O.6
De Gruijl, T.D.7
Van Kooyk, Y.8
Unger, W.W.9
-
26
-
-
77954507341
-
Notch2 signaling is required for potent antitumor immunity in vivo
-
Sugimoto, K., Y. Maekawa, A. Kitamura, J. Nishida, A. Koyanagi, H. Yagita, H. Kojima, S. Chiba, M. Shimada, and K. Yasutomo. 2010. Notch2 signaling is required for potent antitumor immunity in vivo. J. Immunol. 184: 4673-4678.
-
(2010)
J. Immunol.
, vol.184
, pp. 4673-4678
-
-
Sugimoto, K.1
Maekawa, Y.2
Kitamura, A.3
Nishida, J.4
Koyanagi, A.5
Yagita, H.6
Kojima, H.7
Chiba, S.8
Shimada, M.9
Yasutomo, K.10
-
27
-
-
78650996522
-
Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease
-
Zhang, Y., A. R. Sandy, J. Wang, V. Radojcic, G. T. Shan, I. T. Tran, A. Friedman, K. Kato, S. He, S. Cui, et al. 2011. Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease. Blood 117: 299-308.
-
(2011)
Blood
, vol.117
, pp. 299-308
-
-
Zhang, Y.1
Sandy, A.R.2
Wang, J.3
Radojcic, V.4
Shan, G.T.5
Tran, I.T.6
Friedman, A.7
Kato, K.8
He, S.9
Cui, S.10
-
28
-
-
84878102902
-
T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells
-
Sandy, A. R., J. Chung, T. Toubai, G. T. Shan, I. T. Tran, A. Friedman, T. S. Blackwell, P. Reddy, P. D. King, and I. Maillard. 2013. T cell-specific notch inhibition blocks graft-versus-host disease by inducing a hyporesponsive program in alloreactive CD4+ and CD8+ T cells. J. Immunol. 190: 5818-5828.
-
(2013)
J. Immunol.
, vol.190
, pp. 5818-5828
-
-
Sandy, A.R.1
Chung, J.2
Toubai, T.3
Shan, G.T.4
Tran, I.T.5
Friedman, A.6
Blackwell, T.S.7
Reddy, P.8
King, P.D.9
Maillard, I.10
-
29
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist, K. A., S. C. Jameson, W. R. Heath, J. L. Howard, M. J. Bevan, and F. R. Carbone. 1994. T cell receptor antagonist peptides induce positive selection. Cell 76: 17-27.
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
30
-
-
1842665708
-
Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway
-
Yang, X., R. Klein, X. Tian, H. T. Cheng, R. Kopan, and J. Shen. 2004. Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway. Dev. Biol. 269: 81-94.
-
(2004)
Dev. Biol.
, vol.269
, pp. 81-94
-
-
Yang, X.1
Klein, R.2
Tian, X.3
Cheng, H.T.4
Kopan, R.5
Shen, J.6
-
31
-
-
32344440732
-
Generation of new Notch2 mutant alleles
-
McCright, B., J. Lozier, and T. Gridley. 2006. Generation of new Notch2 mutant alleles. Genesis 44: 29-33.
-
(2006)
Genesis
, vol.44
, pp. 29-33
-
-
McCright, B.1
Lozier, J.2
Gridley, T.3
-
32
-
-
33750464087
-
Cytosolic entry controls CD8+-T-cell potency during bacterial infection
-
Bahjat, K. S., W. Liu, E. E. Lemmens, S. P. Schoenberger, D. A. Portnoy, T. W. Dubensky, Jr., and D. G. Brockstedt. 2006. Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect. Immun. 74: 6387-6397.
-
(2006)
Infect. Immun.
, vol.74
, pp. 6387-6397
-
-
Bahjat, K.S.1
Liu, W.2
Lemmens, E.E.3
Schoenberger, S.P.4
Portnoy, D.A.5
Dubensky, T.W.6
Brockstedt, D.G.7
-
33
-
-
25444446578
-
IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization
-
Lacombe, M. H., M. P. Hardy, J. Rooney, and N. Labrecque. 2005. IL-7 receptor expression levels do not identify CD8+ memory T lymphocyte precursors following peptide immunization. J. Immunol. 175: 4400-4407.
-
(2005)
J. Immunol.
, vol.175
, pp. 4400-4407
-
-
Lacombe, M.H.1
Hardy, M.P.2
Rooney, J.3
Labrecque, N.4
-
34
-
-
34548390650
-
IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade
-
Ostiguy, V., E. L. Allard, M. Marquis, J. Leignadier, and N. Labrecque. 2007. IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade. J. Leukoc. Biol. 82: 645-656.
-
(2007)
J. Leukoc. Biol.
, vol.82
, pp. 645-656
-
-
Ostiguy, V.1
Allard, E.L.2
Marquis, M.3
Leignadier, J.4
Labrecque, N.5
-
35
-
-
84856164141
-
CD40-activated B cells can efficiently prime antigen-specific naive CD8+ T cells to generate effector but not memory T cells
-
Mathieu, M., N. Cotta-Grand, J. F. Daudelin, S. Boulet, R. Lapointe, and N. Labrecque. 2012. CD40-activated B cells can efficiently prime antigen-specific naive CD8+ T cells to generate effector but not memory T cells. PLoS One 7: e30139.
-
(2012)
PLoS One
, vol.7
-
-
Mathieu, M.1
Cotta-Grand, N.2
Daudelin, J.F.3
Boulet, S.4
Lapointe, R.5
Labrecque, N.6
-
36
-
-
84862026249
-
Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins
-
Zheng, J., H. Watanabe, M. Wines-Samuelson, H. Zhao, T. Gridley, R. Kopan, and J. Shen. 2012. Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins. J. Biol. Chem. 287: 20356-20368.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 20356-20368
-
-
Zheng, J.1
Watanabe, H.2
Wines-Samuelson, M.3
Zhao, H.4
Gridley, T.5
Kopan, R.6
Shen, J.7
-
37
-
-
84872154060
-
Notch signaling regulates PD-1 expression during CD8(+) T-cell activation
-
Mathieu, M., N. Cotta-Grand, J. F. Daudelin, P. Thébault, and N. Labrecque. 2013. Notch signaling regulates PD-1 expression during CD8(+) T-cell activation. Immunol. Cell Biol. 91: 82-88.
-
(2013)
Immunol. Cell Biol.
, vol.91
, pp. 82-88
-
-
Mathieu, M.1
Cotta-Grand, N.2
Daudelin, J.F.3
Thébault, P.4
Labrecque, N.5
-
38
-
-
73349133349
-
Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies
-
Fiorini, E., E. Merck, A. Wilson, I. Ferrero, W. Jiang, U. Koch, F. Auderset, E. Laurenti, F. Tacchini-Cottier, M. Pierres, et al. 2009. Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. J. Immunol. 183: 7212-7222.
-
(2009)
J. Immunol.
, vol.183
, pp. 7212-7222
-
-
Fiorini, E.1
Merck, E.2
Wilson, A.3
Ferrero, I.4
Jiang, W.5
Koch, U.6
Auderset, F.7
Laurenti, E.8
Tacchini-Cottier, F.9
Pierres, M.10
-
39
-
-
84875837518
-
Blockade of individual Notch ligands and receptors controls graft-versus-host disease
-
Tran, I. T., A. R. Sandy, A. J. Carulli, C. Ebens, J. Chung, G. T. Shan, V. Radojcic, A. Friedman, T. Gridley, A. Shelton, et al. 2013. Blockade of individual Notch ligands and receptors controls graft-versus-host disease. J. Clin. Invest. 123: 1590-1604.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1590-1604
-
-
Tran, I.T.1
Sandy, A.R.2
Carulli, A.J.3
Ebens, C.4
Chung, J.5
Shan, G.T.6
Radojcic, V.7
Friedman, A.8
Gridley, T.9
Shelton, A.10
-
40
-
-
81455135900
-
Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation
-
Obar, J. J., E. R. Jellison, B. S. Sheridan, D. A. Blair, Q. M. Pham, J. M. Zickovich, and L. Lefrançois. 2011. Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation. J. Immunol. 187: 4967-4978.
-
(2011)
J. Immunol.
, vol.187
, pp. 4967-4978
-
-
Obar, J.J.1
Jellison, E.R.2
Sheridan, B.S.3
Blair, D.A.4
Pham, Q.M.5
Zickovich, J.M.6
Lefrançois, L.7
-
41
-
-
22544448946
-
Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination
-
Badovinac, V. P., K. A. Messingham, A. Jabbari, J. S. Haring, and J. T. Harty. 2005. Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nat. Med. 11: 748-756.
-
(2005)
Nat. Med.
, vol.11
, pp. 748-756
-
-
Badovinac, V.P.1
Messingham, K.A.2
Jabbari, A.3
Haring, J.S.4
Harty, J.T.5
-
42
-
-
70149106207
-
A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation
-
Pham, N. L., V. P. Badovinac, and J. T. Harty. 2009. A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation. J. Immunol. 183: 2337-2348.
-
(2009)
J. Immunol.
, vol.183
, pp. 2337-2348
-
-
Pham, N.L.1
Badovinac, V.P.2
Harty, J.T.3
-
43
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
-
Pipkin, M. E., J. A. Sacks, F. Cruz-Guilloty, M. G. Lichtenheld, M. J. Bevan, and A. Rao. 2010. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32: 79-90.
-
(2010)
Immunity
, vol.32
, pp. 79-90
-
-
Pipkin, M.E.1
Sacks, J.A.2
Cruz-Guilloty, F.3
Lichtenheld, M.G.4
Bevan, M.J.5
Rao, A.6
-
44
-
-
33749327182
-
The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor
-
Maillard, I., L. Tu, A. Sambandam, Y. Yashiro-Ohtani, J. Millholland, K. Keeshan, O. Shestova, L. Xu, A. Bhandoola, and W. S. Pear. 2006. The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. J. Exp. Med. 203: 2239-2245.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2239-2245
-
-
Maillard, I.1
Tu, L.2
Sambandam, A.3
Yashiro-Ohtani, Y.4
Millholland, J.5
Keeshan, K.6
Shestova, O.7
Xu, L.8
Bhandoola, A.9
Pear, W.S.10
-
45
-
-
0042834334
-
Notch signaling augments T cell responsiveness by enhancing CD25 expression
-
Adler, S. H., E. Chiffoleau, L. Xu, N. M. Dalton, J. M. Burg, A. D. Wells, M. S. Wolfe, L. A. Turka, and W. S. Pear. 2003. Notch signaling augments T cell responsiveness by enhancing CD25 expression. J. Immunol. 171: 2896-2903.
-
(2003)
J. Immunol.
, vol.171
, pp. 2896-2903
-
-
Adler, S.H.1
Chiffoleau, E.2
Xu, L.3
Dalton, N.M.4
Burg, J.M.5
Wells, A.D.6
Wolfe, M.S.7
Turka, L.A.8
Pear, W.S.9
-
46
-
-
30044440799
-
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
-
Intlekofer, A. M., N. Takemoto, E. J. Wherry, S. A. Longworth, J. T. Northrup, V. R. Palanivel, A. C. Mullen, C. R. Gasink, S. M. Kaech, J. D. Miller, et al. 2005. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 6: 1236-1244.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1236-1244
-
-
Intlekofer, A.M.1
Takemoto, N.2
Wherry, E.J.3
Longworth, S.A.4
Northrup, J.T.5
Palanivel, V.R.6
Mullen, A.C.7
Gasink, C.R.8
Kaech, S.M.9
Miller, J.D.10
-
47
-
-
47749141467
-
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin
-
Intlekofer, A. M., A. Banerjee, N. Takemoto, S. M. Gordon, C. S. Dejong, H. Shin, C. A. Hunter, E. J. Wherry, T. Lindsten, and S. L. Reiner. 2008. Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin. Science 321: 408-411.
-
(2008)
Science
, vol.321
, pp. 408-411
-
-
Intlekofer, A.M.1
Banerjee, A.2
Takemoto, N.3
Gordon, S.M.4
Dejong, C.S.5
Shin, H.6
Hunter, C.A.7
Wherry, E.J.8
Lindsten, T.9
Reiner, S.L.10
-
48
-
-
34848851449
-
A role for IFN-gamma from antigen-specific CD8+ T cells in protective immunity to Listeria monocytogenes
-
Messingham, K. A., V. P. Badovinac, A. Jabbari, and J. T. Harty. 2007. A role for IFN-gamma from antigen-specific CD8+ T cells in protective immunity to Listeria monocytogenes. J. Immunol. 179: 2457-2466.
-
(2007)
J. Immunol.
, vol.179
, pp. 2457-2466
-
-
Messingham, K.A.1
Badovinac, V.P.2
Jabbari, A.3
Harty, J.T.4
-
49
-
-
5044222206
-
Immune responses to Listeria monocytogenes
-
Pamer, E. G. 2004. Immune responses to Listeria monocytogenes. Nat. Rev. Immunol. 4: 812-823.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 812-823
-
-
Pamer, E.G.1
-
50
-
-
84911171912
-
A central role for Notch in effector CD8(+) T cell differentiation
-
Backer, R. A., C. Helbig, R. Gentek, A. Kent, B. J. Laidlaw, C. X. Dominguez, Y. S. de Souza, S. E. van Trierum, R. van Beek, G. F. Rimmelzwaan, et al. 2014. A central role for Notch in effector CD8(+) T cell differentiation. Nat. Immunol. 15: 1143-1151.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1143-1151
-
-
Backer, R.A.1
Helbig, C.2
Gentek, R.3
Kent, A.4
Laidlaw, B.J.5
Dominguez, C.X.6
De Souza, Y.S.7
Van Trierum, S.E.8
Van Beek, R.9
Rimmelzwaan, G.F.10
-
51
-
-
33751584436
-
Cutting edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation
-
Takemoto, N., A. M. Intlekofer, J. T. Northrup, E. J. Wherry, and S. L. Reiner. 2006. Cutting edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation. J. Immunol. 177: 7515-7519.
-
(2006)
J. Immunol.
, vol.177
, pp. 7515-7519
-
-
Takemoto, N.1
Intlekofer, A.M.2
Northrup, J.T.3
Wherry, E.J.4
Reiner, S.L.5
-
52
-
-
42449110816
-
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
-
Sinclair, L. V., D. Finlay, C. Feijoo, G. H. Cornish, A. Gray, A. Ager, K. Okkenhaug, T. J. Hagenbeek, H. Spits, and D. A. Cantrell. 2008. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat. Immunol. 9: 513-521.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 513-521
-
-
Sinclair, L.V.1
Finlay, D.2
Feijoo, C.3
Cornish, G.H.4
Gray, A.5
Ager, A.6
Okkenhaug, K.7
Hagenbeek, T.J.8
Spits, H.9
Cantrell, D.A.10
-
53
-
-
33745837261
-
Differential regulation of T-cell growth by IL-2 and IL-15
-
Cornish, G. H., L. V. Sinclair, and D. A. Cantrell. 2006. Differential regulation of T-cell growth by IL-2 and IL-15. Blood 108: 600-608.
-
(2006)
Blood
, vol.108
, pp. 600-608
-
-
Cornish, G.H.1
Sinclair, L.V.2
Cantrell, D.A.3
-
54
-
-
84860342013
-
Signal integration by Akt regulates CD8 T cell effector and memory differentiation
-
Kim, E. H., J. A. Sullivan, E. H. Plisch, M. M. Tejera, A. Jatzek, K. Y. Choi, and M. Suresh. 2012. Signal integration by Akt regulates CD8 T cell effector and memory differentiation. J. Immunol. 188: 4305-4314.
-
(2012)
J. Immunol.
, vol.188
, pp. 4305-4314
-
-
Kim, E.H.1
Sullivan, J.A.2
Plisch, E.H.3
Tejera, M.M.4
Jatzek, A.5
Choi, K.Y.6
Suresh, M.7
-
55
-
-
79951745387
-
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
-
Macintyre, A. N., D. Finlay, G. Preston, L. V. Sinclair, C. M. Waugh, P. Tamas, C. Feijoo, K. Okkenhaug, and D. A. Cantrell. 2011. Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. Immunity 34: 224-236.
-
(2011)
Immunity
, vol.34
, pp. 224-236
-
-
Macintyre, A.N.1
Finlay, D.2
Preston, G.3
Sinclair, L.V.4
Waugh, C.M.5
Tamas, P.6
Feijoo, C.7
Okkenhaug, K.8
Cantrell, D.A.9
-
56
-
-
85027948869
-
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
-
Guy, C. S., K. M. Vignali, J. Temirov, M. L. Bettini, A. E. Overacre, M. Smeltzer, H. Zhang, J. B. Huppa, Y. H. Tsai, C. Lobry, et al. 2013. Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat. Immunol. 14: 262-270.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 262-270
-
-
Guy, C.S.1
Vignali, K.M.2
Temirov, J.3
Bettini, M.L.4
Overacre, A.E.5
Smeltzer, M.6
Zhang, H.7
Huppa, J.B.8
Tsai, Y.H.9
Lobry, C.10
-
57
-
-
84895509804
-
Non-canonical Notch signaling drives activation and differentiation of peripheral CD4(+) T cells
-
Dongre, A., L. Surampudi, R. G. Lawlor, A. H. Fauq, L. Miele, T. E. Golde, L. M. Minter, and B. A. Osborne. 2014. Non-canonical Notch signaling drives activation and differentiation of peripheral CD4(+) T cells. Front. Immunol. 5: 54.
-
(2014)
Front. Immunol.
, vol.5
, pp. 54
-
-
Dongre, A.1
Surampudi, L.2
Lawlor, R.G.3
Fauq, A.H.4
Miele, L.5
Golde, T.E.6
Minter, L.M.7
Osborne, B.A.8
-
58
-
-
84905407019
-
NOTCH1 can initiate NF-κB activation via cytosolic interactions with components of the T cell signalosome
-
Shin, H. M., M. E. Tilahun, O. H. Cho, K. Chandiran, C. A. Kuksin, S. Keerthivasan, A. H. Fauq, T. E. Golde, L. Miele, M. Thome, et al. 2014. NOTCH1 can initiate NF-κB activation via cytosolic interactions with components of the T cell signalosome. Front. Immunol. 5: 249.
-
(2014)
Front. Immunol.
, vol.5
, pp. 249
-
-
Shin, H.M.1
Tilahun, M.E.2
Cho, O.H.3
Chandiran, K.4
Kuksin, C.A.5
Keerthivasan, S.6
Fauq, A.H.7
Golde, T.E.8
Miele, L.9
Thome, M.10
-
59
-
-
0031985628
-
Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha
-
White, D. W., and J. T. Harty. 1998. Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha. J. Immunol. 160: 898-905.
-
(1998)
J. Immunol.
, vol.160
, pp. 898-905
-
-
White, D.W.1
Harty, J.T.2
-
60
-
-
4444253689
-
CD8+ T cell contraction is controlled by early inflammation
-
Badovinac, V. P., B. B. Porter, and J. T. Harty. 2004. CD8+ T cell contraction is controlled by early inflammation. Nat. Immunol. 5: 809-817.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 809-817
-
-
Badovinac, V.P.1
Porter, B.B.2
Harty, J.T.3
-
61
-
-
0034680811
-
Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma
-
Badovinac, V. P., A. R. Tvinnereim, and J. T. Harty. 2000. Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma. Science 290: 1354-1358.
-
(2000)
Science
, vol.290
, pp. 1354-1358
-
-
Badovinac, V.P.1
Tvinnereim, A.R.2
Harty, J.T.3
|