A central role for Notch in effector CD8 + T cell differentiation

Nature Immunology

Volumn 15, Issue 12, 2014, Pages 1143-1151

  Backer, Ronald A ^a,b,f   Helbig, Christina ^a,b   Gentek, Rebecca ^a   Kent, Andrew ^c   Laidlaw, Brian J ^d   Dominguez, Claudia X ^d   De Souza, Yevan S ^a   Van Trierum, Stella E ^e,g   Van Beek, Ruud ^e,g   Rimmelzwaan, Guus F ^e,g   Ten Brinke, Anja ^b   Willemsen, A Marcel ^a   Van Kampen, Antoine H C ^a   Kaech, Susan M ^d   Blander, J Magarian ^c   Van Gisbergen, Klaas ^b   Amsen, Derk ^a,b  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b SANQUIN RESEARCH   (Netherlands)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^g ViroClinics Biosciences   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; MAMMALIAN TARGET OF RAPAMYCIN; MYELOID DIFFERENTIATION FACTOR 88; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NUCLEOPROTEIN; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; RESIQUIMOD; TRANSCRIPTION FACTOR T BET; NOTCH RECEPTOR; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; EFFECTOR CELL; FEMALE; GENE EXPRESSION; INFLUENZA A; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; POSITIVE FEEDBACK; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TERMINAL EFFECTOR CELL; VIRUS LOAD; ADAPTIVE IMMUNITY; ADOPTIVE TRANSFER; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL SEPARATION; CYTOLOGY; FLOW CYTOMETRY; GENETIC TRANSDUCTION; IMMUNOLOGY; INFLUENZA VIRUS A; LYMPHOCYTE ACTIVATION; ORTHOMYXOVIRUS INFECTION; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ADAPTIVE IMMUNITY; ADOPTIVE TRANSFER; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL SEPARATION; FLOW CYTOMETRY; INFLUENZA A VIRUS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORTHOMYXOVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; T-LYMPHOCYTE SUBSETS; TRANSCRIPTOME; TRANSDUCTION, GENETIC;

EID: 84911171912     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3027     Document Type: Article

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