-
1
-
-
2342496710
-
Instruction of distinct CD4T helper cell fates by different notch ligands on antigen-presenting cells
-
Amsen D., Blander J.M., Lee G.R., Tanigaki K., Honjo T., Flavell R.A. Instruction of distinct CD4T helper cell fates by different notch ligands on antigen-presenting cells. Cell 2004, 117:515-526.
-
(2004)
Cell
, vol.117
, pp. 515-526
-
-
Amsen, D.1
Blander, J.M.2
Lee, G.R.3
Tanigaki, K.4
Honjo, T.5
Flavell, R.A.6
-
2
-
-
34447634411
-
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
-
Amsen D., Antov A., Jankovic D., Sher A., Radtke F., Souabni A., Busslinger M., McCright B., Gridley T., Flavell R.A. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007, 27:89-99.
-
(2007)
Immunity
, vol.27
, pp. 89-99
-
-
Amsen, D.1
Antov, A.2
Jankovic, D.3
Sher, A.4
Radtke, F.5
Souabni, A.6
Busslinger, M.7
McCright, B.8
Gridley, T.9
Flavell, R.A.10
-
3
-
-
58849099058
-
The different faces of Notch in T-helper-cell differentiation
-
Amsen D., Antov A., Flavell R.A. The different faces of Notch in T-helper-cell differentiation. Nat. Rev. Immunol. 2009, 9:116-124.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 116-124
-
-
Amsen, D.1
Antov, A.2
Flavell, R.A.3
-
4
-
-
0037108366
-
Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation
-
Artis D., Shapira S., Mason N., Speirs K.M., Goldschmidt M., Caamaño J., Liou H.C., Hunter C.A., Scott P. Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. J.Immunol. 2002, 169:4481-4487.
-
(2002)
J.Immunol.
, vol.169
, pp. 4481-4487
-
-
Artis, D.1
Shapira, S.2
Mason, N.3
Speirs, K.M.4
Goldschmidt, M.5
Caamaño, J.6
Liou, H.C.7
Hunter, C.A.8
Scott, P.9
-
5
-
-
0033796150
-
Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1
-
Aster J.C., Xu L., Karnell F.G., Patriub V., Pui J.C., Pear W.S. Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1. Mol. Cell. Biol. 2000, 20:7505-7515.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7505-7515
-
-
Aster, J.C.1
Xu, L.2
Karnell, F.G.3
Patriub, V.4
Pui, J.C.5
Pear, W.S.6
-
6
-
-
84863598267
-
Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major
-
Auderset F., Schuster S., Coutaz M., Koch U., Desgranges F., Merck E., MacDonald H.R., Radtke F., Tacchini-Cottier F. Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major. PLoS Pathog. 2012, 8:e1002560.
-
(2012)
PLoS Pathog.
, vol.8
-
-
Auderset, F.1
Schuster, S.2
Coutaz, M.3
Koch, U.4
Desgranges, F.5
Merck, E.6
MacDonald, H.R.7
Radtke, F.8
Tacchini-Cottier, F.9
-
7
-
-
77954903767
-
Modular utilization of distal cis-regulatory elements controls Ifng gene expression in Tcells activated by distinct stimuli
-
Balasubramani A., Shibata Y., Crawford G.E., Baldwin A.S., Hatton R.D., Weaver C.T. Modular utilization of distal cis-regulatory elements controls Ifng gene expression in Tcells activated by distinct stimuli. Immunity 2010, 33:35-47.
-
(2010)
Immunity
, vol.33
, pp. 35-47
-
-
Balasubramani, A.1
Shibata, Y.2
Crawford, G.E.3
Baldwin, A.S.4
Hatton, R.D.5
Weaver, C.T.6
-
8
-
-
0035024482
-
B cells and antibodies are required for resistance to the parasitic gastrointestinal nematode Trichuris muris
-
Blackwell N.M., Else K.J. B cells and antibodies are required for resistance to the parasitic gastrointestinal nematode Trichuris muris. Infect. Immun. 2001, 69:3860-3868.
-
(2001)
Infect. Immun.
, vol.69
, pp. 3860-3868
-
-
Blackwell, N.M.1
Else, K.J.2
-
9
-
-
7044245719
-
The Trichuris muris system: a paradigm of resistance and susceptibility to intestinal nematode infection
-
Cliffe L.J., Grencis R.K. The Trichuris muris system: a paradigm of resistance and susceptibility to intestinal nematode infection. Adv. Parasitol. 2004, 57:255-307.
-
(2004)
Adv. Parasitol.
, vol.57
, pp. 255-307
-
-
Cliffe, L.J.1
Grencis, R.K.2
-
10
-
-
20344379481
-
Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion
-
Cliffe L.J., Humphreys N.E., Lane T.E., Potten C.S., Booth C., Grencis R.K. Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion. Science 2005, 308:1463-1465.
-
(2005)
Science
, vol.308
, pp. 1463-1465
-
-
Cliffe, L.J.1
Humphreys, N.E.2
Lane, T.E.3
Potten, C.S.4
Booth, C.5
Grencis, R.K.6
-
11
-
-
79953123445
-
Effector CD4+ Tcells, the cytokines they generate, and GVHD: something old and something new
-
Coghill J.M., Sarantopoulos S., Moran T.P., Murphy W.J., Blazar B.R., Serody J.S. Effector CD4+ Tcells, the cytokines they generate, and GVHD: something old and something new. Blood 2011, 117:3268-3276.
-
(2011)
Blood
, vol.117
, pp. 3268-3276
-
-
Coghill, J.M.1
Sarantopoulos, S.2
Moran, T.P.3
Murphy, W.J.4
Blazar, B.R.5
Serody, J.S.6
-
12
-
-
0028006251
-
Cytokine-mediated regulation of chronic intestinal helminth infection
-
Else K.J., Finkelman F.D., Maliszewski C.R., Grencis R.K. Cytokine-mediated regulation of chronic intestinal helminth infection. J.Exp. Med. 1994, 179:347-351.
-
(1994)
J.Exp. Med.
, vol.179
, pp. 347-351
-
-
Else, K.J.1
Finkelman, F.D.2
Maliszewski, C.R.3
Grencis, R.K.4
-
13
-
-
34447642439
-
Notch directly regulates Gata3 expression during T helper 2 cell differentiation
-
Fang T.C., Yashiro-Ohtani Y., Del Bianco C., Knoblock D.M., Blacklow S.C., Pear W.S. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 2007, 27:100-110.
-
(2007)
Immunity
, vol.27
, pp. 100-110
-
-
Fang, T.C.1
Yashiro-Ohtani, Y.2
Del Bianco, C.3
Knoblock, D.M.4
Blacklow, S.C.5
Pear, W.S.6
-
14
-
-
84857398262
-
The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper Tcells
-
Harada Y., Tanaka S., Motomura Y., Harada Y., Ohno S., Ohno S., Yanagi Y., Inoue H., Kubo M. The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper Tcells. Immunity 2012, 36:188-200.
-
(2012)
Immunity
, vol.36
, pp. 188-200
-
-
Harada, Y.1
Tanaka, S.2
Motomura, Y.3
Harada, Y.4
Ohno, S.5
Ohno, S.6
Yanagi, Y.7
Inoue, H.8
Kubo, M.9
-
15
-
-
33846208370
-
A distal conserved sequence element controls Ifng gene expression by Tcells and NK cells
-
Hatton R.D., Harrington L.E., Luther R.J., Wakefield T., Janowski K.M., Oliver J.R., Lallone R.L., Murphy K.M., Weaver C.T. A distal conserved sequence element controls Ifng gene expression by Tcells and NK cells. Immunity 2006, 25:717-729.
-
(2006)
Immunity
, vol.25
, pp. 717-729
-
-
Hatton, R.D.1
Harrington, L.E.2
Luther, R.J.3
Wakefield, T.4
Janowski, K.M.5
Oliver, J.R.6
Lallone, R.L.7
Murphy, K.M.8
Weaver, C.T.9
-
16
-
-
84861893409
-
Notch controls the magnitude of T helper cell responses by promoting cellular longevity
-
Helbig C., Gentek R., Backer R.A., de Souza Y., Derks I.A., Eldering E., Wagner K., Jankovic D., Gridley T., Moerland P.D., et al. Notch controls the magnitude of T helper cell responses by promoting cellular longevity. Proc. Natl. Acad. Sci. USA 2012, 109:9041-9046.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 9041-9046
-
-
Helbig, C.1
Gentek, R.2
Backer, R.A.3
de Souza, Y.4
Derks, I.A.5
Eldering, E.6
Wagner, K.7
Jankovic, D.8
Gridley, T.9
Moerland, P.D.10
-
17
-
-
79960544098
-
Notch signaling regulates mouse and human Th17 differentiation
-
Keerthivasan S., Suleiman R., Lawlor R., Roderick J., Bates T., Minter L., Anguita J., Juncadella I., Nickoloff B.J., Le Poole I.C., et al. Notch signaling regulates mouse and human Th17 differentiation. J.Immunol. 2011, 187:692-701.
-
(2011)
J.Immunol.
, vol.187
, pp. 692-701
-
-
Keerthivasan, S.1
Suleiman, R.2
Lawlor, R.3
Roderick, J.4
Bates, T.5
Minter, L.6
Anguita, J.7
Juncadella, I.8
Nickoloff, B.J.9
Le Poole, I.C.10
-
18
-
-
64249172203
-
The canonical Notch signaling pathway: unfolding the activation mechanism
-
Kopan R., Ilagan M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009, 137:216-233.
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
19
-
-
34447628669
-
Notch: filling a hole in T helper 2 cell differentiation
-
Kubo M. Notch: filling a hole in T helper 2 cell differentiation. Immunity 2007, 27:3-5.
-
(2007)
Immunity
, vol.27
, pp. 3-5
-
-
Kubo, M.1
-
20
-
-
84869508434
-
The CD46-Jagged1 interaction is critical for human TH1 immunity
-
Le Friec G., Sheppard D., Whiteman P., Karsten C.M., Shamoun S.A., Laing A., Bugeon L., Dallman M.J., Melchionna T., Chillakuri C., et al. The CD46-Jagged1 interaction is critical for human TH1 immunity. Nat. Immunol. 2012, 13:1213-1221.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1213-1221
-
-
Le Friec, G.1
Sheppard, D.2
Whiteman, P.3
Karsten, C.M.4
Shamoun, S.A.5
Laing, A.6
Bugeon, L.7
Dallman, M.J.8
Melchionna, T.9
Chillakuri, C.10
-
21
-
-
0142157141
-
Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ Tcells
-
Maekawa Y., Tsukumo S., Chiba S., Hirai H., Hayashi Y., Okada H., Kishihara K., Yasutomo K. Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ Tcells. Immunity 2003, 19:549-559.
-
(2003)
Immunity
, vol.19
, pp. 549-559
-
-
Maekawa, Y.1
Tsukumo, S.2
Chiba, S.3
Hirai, H.4
Hayashi, Y.5
Okada, H.6
Kishihara, K.7
Yasutomo, K.8
-
22
-
-
22144492615
-
Inhibitors of gamma-secretase block invivo and invitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
-
Minter L.M., Turley D.M., Das P., Shin H.M., Joshi I., Lawlor R.G., Cho O.H., Palaga T., Gottipati S., Telfer J.C., et al. Inhibitors of gamma-secretase block invivo and invitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nat. Immunol. 2005, 6:680-688.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 680-688
-
-
Minter, L.M.1
Turley, D.M.2
Das, P.3
Shin, H.M.4
Joshi, I.5
Lawlor, R.G.6
Cho, O.H.7
Palaga, T.8
Gottipati, S.9
Telfer, J.C.10
-
23
-
-
67649216137
-
Regulation of Tcell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation
-
Mukherjee S., Schaller M.A., Neupane R., Kunkel S.L., Lukacs N.W. Regulation of Tcell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation. J.Immunol. 2009, 182:7381-7388.
-
(2009)
J.Immunol.
, vol.182
, pp. 7381-7388
-
-
Mukherjee, S.1
Schaller, M.A.2
Neupane, R.3
Kunkel, S.L.4
Lukacs, N.W.5
-
24
-
-
77954948735
-
Effector Tcell plasticity: flexibility in the face of changing circumstances
-
Murphy K.M., Stockinger B. Effector Tcell plasticity: flexibility in the face of changing circumstances. Nat. Immunol. 2010, 11:674-680.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 674-680
-
-
Murphy, K.M.1
Stockinger, B.2
-
25
-
-
70349238800
-
Jagged1 on dendritic cells and Notch on CD4+ Tcells initiate lung allergic responsiveness by inducing IL-4 production
-
Okamoto M., Matsuda H., Joetham A., Lucas J.J., Domenico J., Yasutomo K., Takeda K., Gelfand E.W. Jagged1 on dendritic cells and Notch on CD4+ Tcells initiate lung allergic responsiveness by inducing IL-4 production. J.Immunol. 2009, 183:2995-3003.
-
(2009)
J.Immunol.
, vol.183
, pp. 2995-3003
-
-
Okamoto, M.1
Matsuda, H.2
Joetham, A.3
Lucas, J.J.4
Domenico, J.5
Yasutomo, K.6
Takeda, K.7
Gelfand, E.W.8
-
26
-
-
50949091487
-
Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition
-
Ong C.T., Sedy J.R., Murphy K.M., Kopan R. Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS ONE 2008, 3:e2823.
-
(2008)
PLoS ONE
, vol.3
-
-
Ong, C.T.1
Sedy, J.R.2
Murphy, K.M.3
Kopan, R.4
-
27
-
-
33645896155
-
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract
-
Owyang A.M., Zaph C., Wilson E.H., Guild K.J., McClanahan T., Miller H.R., Cua D.J., Goldschmidt M., Hunter C.A., Kastelein R.A., Artis D. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J.Exp. Med. 2006, 203:843-849.
-
(2006)
J.Exp. Med.
, vol.203
, pp. 843-849
-
-
Owyang, A.M.1
Zaph, C.2
Wilson, E.H.3
Guild, K.J.4
McClanahan, T.5
Miller, H.R.6
Cua, D.J.7
Goldschmidt, M.8
Hunter, C.A.9
Kastelein, R.A.10
Artis, D.11
-
29
-
-
65549118531
-
Sequential polarization and imprinting of type 1T helper lymphocytes by interferon-gamma and interleukin-12
-
Schulz E.G., Mariani L., Radbruch A., Höfer T. Sequential polarization and imprinting of type 1T helper lymphocytes by interferon-gamma and interleukin-12. Immunity 2009, 30:673-683.
-
(2009)
Immunity
, vol.30
, pp. 673-683
-
-
Schulz, E.G.1
Mariani, L.2
Radbruch, A.3
Höfer, T.4
-
30
-
-
34447254518
-
CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS
-
Skokos D., Nussenzweig M.C. CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS. J.Exp. Med. 2007, 204:1525-1531.
-
(2007)
J.Exp. Med.
, vol.204
, pp. 1525-1531
-
-
Skokos, D.1
Nussenzweig, M.C.2
-
31
-
-
63449112387
-
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis
-
Taylor B.C., Zaph C., Troy A.E., Du Y., Guild K.J., Comeau M.R., Artis D. TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis. J.Exp. Med. 2009, 206:655-667.
-
(2009)
J.Exp. Med.
, vol.206
, pp. 655-667
-
-
Taylor, B.C.1
Zaph, C.2
Troy, A.E.3
Du, Y.4
Guild, K.J.5
Comeau, M.R.6
Artis, D.7
-
32
-
-
13844320399
-
T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site
-
Tong Y., Aune T., Boothby M. T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site. Proc. Natl. Acad. Sci. USA 2005, 102:2034-2039.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2034-2039
-
-
Tong, Y.1
Aune, T.2
Boothby, M.3
-
33
-
-
26844538164
-
Notch signaling is an important regulator of type 2 immunity
-
Tu L., Fang T.C., Artis D., Shestova O., Pross S.E., Maillard I., Pear W.S. Notch signaling is an important regulator of type 2 immunity. J.Exp. Med. 2005, 202:1037-1042.
-
(2005)
J.Exp. Med.
, vol.202
, pp. 1037-1042
-
-
Tu, L.1
Fang, T.C.2
Artis, D.3
Shestova, O.4
Pross, S.E.5
Maillard, I.6
Pear, W.S.7
-
34
-
-
33645065358
-
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
-
Usui T., Preiss J.C., Kanno Y., Yao Z.J., Bream J.H., O'Shea J.J., Strober W. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J.Exp. Med. 2006, 203:755-766.
-
(2006)
J.Exp. Med.
, vol.203
, pp. 755-766
-
-
Usui, T.1
Preiss, J.C.2
Kanno, Y.3
Yao, Z.J.4
Bream, J.H.5
O'Shea, J.J.6
Strober, W.7
-
35
-
-
84863393256
-
Interleukin-4 production by follicular helper Tcells requires the conserved Il4 enhancer hypersensitivity site V
-
Vijayanand P., Seumois G., Simpson L.J., Abdul-Wajid S., Baumjohann D., Panduro M., Huang X., Interlandi J., Djuretic I.M., Brown D.R., et al. Interleukin-4 production by follicular helper Tcells requires the conserved Il4 enhancer hypersensitivity site V. Immunity 2012, 36:175-187.
-
(2012)
Immunity
, vol.36
, pp. 175-187
-
-
Vijayanand, P.1
Seumois, G.2
Simpson, L.J.3
Abdul-Wajid, S.4
Baumjohann, D.5
Panduro, M.6
Huang, X.7
Interlandi, J.8
Djuretic, I.M.9
Brown, D.R.10
-
36
-
-
33746546368
-
C-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
-
Weng A.P., Millholland J.M., Yashiro-Ohtani Y., Arcangeli M.L., Lau A., Wai C., Del Bianco C., Rodriguez C.G., Sai H., Tobias J., et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev. 2006, 20:2096-2109.
-
(2006)
Genes Dev.
, vol.20
, pp. 2096-2109
-
-
Weng, A.P.1
Millholland, J.M.2
Yashiro-Ohtani, Y.3
Arcangeli, M.L.4
Lau, A.5
Wai, C.6
Del Bianco, C.7
Rodriguez, C.G.8
Sai, H.9
Tobias, J.10
-
37
-
-
67650588402
-
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
-
Yashiro-Ohtani Y., He Y., Ohtani T., Jones M.E., Shestova O., Xu L., Fang T.C., Chiang M.Y., Intlekofer A.M., Blacklow S.C., et al. Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A. Genes Dev. 2009, 23:1665-1676.
-
(2009)
Genes Dev.
, vol.23
, pp. 1665-1676
-
-
Yashiro-Ohtani, Y.1
He, Y.2
Ohtani, T.3
Jones, M.E.4
Shestova, O.5
Xu, L.6
Fang, T.C.7
Chiang, M.Y.8
Intlekofer, A.M.9
Blacklow, S.C.10
-
38
-
-
69049088648
-
T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma
-
Yu Q., Sharma A., Oh S.Y., Moon H.G., Hossain M.Z., Salay T.M., Leeds K.E., Du H., Wu B., Waterman M.L., et al. T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma. Nat. Immunol. 2009, 10:992-999.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 992-999
-
-
Yu, Q.1
Sharma, A.2
Oh, S.Y.3
Moon, H.G.4
Hossain, M.Z.5
Salay, T.M.6
Leeds, K.E.7
Du, H.8
Wu, B.9
Waterman, M.L.10
-
39
-
-
78650996522
-
Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease
-
Zhang Y., Sandy A.R., Wang J., Radojcic V., Shan G.T., Tran I.T., Friedman A., Kato K., He S., Cui S., et al. Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease. Blood 2011, 117:299-308.
-
(2011)
Blood
, vol.117
, pp. 299-308
-
-
Zhang, Y.1
Sandy, A.R.2
Wang, J.3
Radojcic, V.4
Shan, G.T.5
Tran, I.T.6
Friedman, A.7
Kato, K.8
He, S.9
Cui, S.10
|