-
1
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992; 11: 3887-3895.
-
(1992)
EMBO J
, vol.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
2
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192: 1027-1034.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
-
3
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
DOI 10.1038/85330
-
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001; 2: 261-268. (Pubitemid 33706004)
-
(2001)
Nature Immunology
, vol.2
, Issue.3
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
Greenfield, E.A.11
Bourque, K.12
Boussiotis, V.A.13
Carter, L.L.14
Carreno, B.M.15
Malenkovich, N.16
Nishimura, H.17
Okazaki, T.18
Honjo, T.19
Sharpe, A.H.20
Freeman, G.J.21
more..
-
4
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
DOI 10.1038/nature04444, PII NATURE04444
-
Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006; 439: 682-687. (Pubitemid 43237609)
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
5
-
-
34249711903
-
+ T-cell exhaustion in typical progressors but not in long-term nonprogressors
-
DOI 10.1182/blood-2006-09-044826
-
Zhang JY, Zhang Z, Wang X, Fu JL, Yao J, Jiao Y et al. PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors. Blood 2007; 109: 4671-4678. (Pubitemid 46827757)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4671-4678
-
-
Zhang, J.-Y.1
Zhang, Z.2
Wang, X.3
Fu, J.-L.4
Yao, J.5
Jiao, Y.6
Chen, L.7
Zhang, H.8
Wei, J.9
Jin, L.10
Shi, M.11
Gao, G.F.12
Wu, H.13
Wang, F.-S.14
-
6
-
-
44649188658
-
Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization
-
Nakamoto N, Kaplan DE, Coleclough J, Li Y, Valiga ME, Kaminski M et al. Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization. Gastroenterology 2008; 134: 37e1-2.
-
(2008)
Gastroenterology
, vol.134
-
-
Nakamoto, N.1
Kaplan, D.E.2
Coleclough, J.3
Li, Y.4
Valiga, M.E.5
Kaminski, M.6
-
7
-
-
33749338938
-
+ T cell survival in HIV infection
-
DOI 10.1084/jem.20061496
-
Petrovas C, Casazza JP, Brenchley JM, Price DA, Gostick E, Adams WC et al. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med 2006; 203: 2281-2292. (Pubitemid 44498363)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.10
, pp. 2281-2292
-
-
Petrovas, C.1
Casazza, J.P.2
Brenchley, J.M.3
Price, D.A.4
Gostick, E.5
Adams, W.C.6
Precopio, M.L.7
Schacker, T.8
Roederer, M.9
Douek, D.C.10
Koup, R.A.11
-
8
-
-
33749009709
-
+ T cells leads to reversible immune dysfunction
-
DOI 10.1038/nm1482, PII NM1482
-
Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med 2006; 12: 1198-1202. (Pubitemid 44527357)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
Boulassel, M.-R.7
Delwart, E.8
Sepulveda, H.9
Balderas, R.S.10
Routy, J.-P.11
Haddad, E.K.12
Sekaly, R.-P.13
-
9
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
DOI 10.1016/S1074-7613(00)80089-8
-
Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999; 11: 141-151. (Pubitemid 29428807)
-
(1999)
Immunity
, vol.11
, Issue.2
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
10
-
-
0037477605
-
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
-
DOI 10.1084/jem.20022125
-
Ansari MJ, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med 2003; 198: 63-69. (Pubitemid 36870186)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.1
, pp. 63-69
-
-
Ansari, M.J.I.1
Salama, A.D.2
Chitnis, T.3
Smith, R.N.4
Yagita, H.5
Akiba, H.6
Yamazaki, T.7
Azuma, M.8
Iwai, H.9
Khoury, S.J.10
Auchincloss Jr., H.11
Sayegh, M.H.12
-
11
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife BT, Pauken KE, Eagar TN, Obu T, Wu J, Tang Q et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol 2009; 10: 1185-1192.
-
(2009)
Nat Immunol
, vol.10
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
Obu, T.4
Wu, J.5
Tang, Q.6
-
12
-
-
58149314579
-
NFATc1 regulates PD-1 expression upon T cell activation
-
Oestreich KJ, Yoon H, Ahmed R, Boss JM. NFATc1 regulates PD-1 expression upon T cell activation. J Immunol 2008; 181: 4832-4839.
-
(2008)
J Immunol
, vol.181
, pp. 4832-4839
-
-
Oestreich, K.J.1
Yoon, H.2
Ahmed, R.3
Boss, J.M.4
-
13
-
-
79952767536
-
IFN-alpha directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity
-
Terawaki S, Chikuma S, Shibayama S, Hayashi T, Yoshida T, Okazaki T et al. IFN-alpha directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity. J Immunol 2011; 186: 2772-2779.
-
(2011)
J Immunol
, vol.186
, pp. 2772-2779
-
-
Terawaki, S.1
Chikuma, S.2
Shibayama, S.3
Hayashi, T.4
Yoshida, T.5
Okazaki, T.6
-
14
-
-
79959375167
-
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virusspecific CD8+ T cell responses during chronic infection
-
Kao C, Oestreich KJ, Paley MA, Crawford A, Angelosanto JM, Ali MA et al. Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virusspecific CD8+ T cell responses during chronic infection. Nat Immunol 2011; 12: 663-671.
-
(2011)
Nat Immunol
, vol.12
, pp. 663-671
-
-
Kao, C.1
Oestreich, K.J.2
Paley, M.A.3
Crawford, A.4
Angelosanto, J.M.5
Ali, M.A.6
-
16
-
-
0032524325
-
Nuclear access and action of Notch in vivo
-
DOI 10.1016/S0092-8674(00)81193-9
-
Struhl G, Adachi A. Nuclear access and action of notch in vivo. Cell 1998; 93: 649-660. (Pubitemid 28240725)
-
(1998)
Cell
, vol.93
, Issue.4
, pp. 649-660
-
-
Struhl, G.1
Adachi, A.2
-
17
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS et al. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 1999; 398: 518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
-
18
-
-
0033561365
-
Hes1 and Hes5 as notch effecters in mammalian neuronal differentiation
-
Ohtsuka T, Ishibashi M, Gradwohl G, Nakanishi S, Guillemot F, Kageyama R. Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J 1999; 18: 2196-2207. (Pubitemid 29179176)
-
(1999)
EMBO Journal
, vol.18
, Issue.8
, pp. 2196-2207
-
-
Ohtsuka, T.1
Ishibashi, M.2
Gradwohl, G.3
Nakanishi, S.4
Guillemot, F.5
Kageyama, R.6
-
19
-
-
0035977003
-
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor
-
Yamamoto N, Yamamoto S, Inagaki F, Kawaichi M, Fukamizu A, Kishi N et al. Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J Biol Chem 2001; 276: 45031-45040.
-
(2001)
J Biol Chem
, vol.276
, pp. 45031-45040
-
-
Yamamoto, N.1
Yamamoto, S.2
Inagaki, F.3
Kawaichi, M.4
Fukamizu, A.5
Kishi, N.6
-
20
-
-
65449183749
-
Notch regulates cytolytic effector function in CD8+ T cells
-
Cho OH, Shin HM, Miele L, Golde TE, Fauq A, Minter LM et al. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol 2009; 182: 3380-3389.
-
(2009)
J Immunol
, vol.182
, pp. 3380-3389
-
-
Cho, O.H.1
Shin, H.M.2
Miele, L.3
Golde, T.E.4
Fauq, A.5
Minter, L.M.6
-
21
-
-
52549130987
-
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
-
Maekawa Y, Minato Y, Ishifune C, Kurihara T, Kitamura A, Kojima H et al. Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat Immunol 2008; 9: 1140-1147.
-
(2008)
Nat Immunol
, vol.9
, pp. 1140-1147
-
-
Maekawa, Y.1
Minato, Y.2
Ishifune, C.3
Kurihara, T.4
Kitamura, A.5
Kojima, H.6
-
22
-
-
40349100486
-
Activity of γ-secretase on substrates other than APP
-
DOI 10.2174/156802608783334060
-
Lleo A. Activity of gamma-secretase on substrates other than APP. Curr Top Med Chem 2008; 8: 9-16. (Pubitemid 351791042)
-
(2008)
Current Topics in Medicinal Chemistry
, vol.8
, Issue.1
, pp. 9-16
-
-
Lleo, A.1
-
23
-
-
33645742986
-
Gamma-secretase-dependent proteolysis of CD44 promotes neoplastic transformation of rat fibroblastic cells
-
Pelletier L, Guillaumot P, Freche B, Luquain C, Christiansen D, Brugiere S et al. Gamma-secretase-dependent proteolysis of CD44 promotes neoplastic transformation of rat fibroblastic cells. Cancer Res 2006; 66: 3681-3687.
-
(2006)
Cancer Res
, vol.66
, pp. 3681-3687
-
-
Pelletier, L.1
Guillaumot, P.2
Freche, B.3
Luquain, C.4
Christiansen, D.5
Brugiere, S.6
-
24
-
-
70449671729
-
Direct inhibition of the NOTCH transcription factor complex
-
Moellering RE, Cornejo M, Davis TN, Del Bianco C, Aster JC, Blacklow SC et al. Direct inhibition of the NOTCH transcription factor complex. Nature 2009; 462: 182-188.
-
(2009)
Nature
, vol.462
, pp. 182-188
-
-
Moellering, R.E.1
Cornejo, M.2
Davis, T.N.3
Del Bianco, C.4
Aster, J.C.5
Blacklow, S.C.6
-
25
-
-
0041331708
-
TCR-mediated Notch signaling regulates proliferation and IFN-γ production in peripheral T cells
-
Palaga T, Miele L, Golde TE, Osborne BA. TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells. J Immunol 2003; 171: 3019-3024. (Pubitemid 37093525)
-
(2003)
Journal of Immunology
, vol.171
, Issue.6
, pp. 3019-3024
-
-
Palaga, T.1
Miele, L.2
Golde, T.E.3
Osborne, B.A.4
-
26
-
-
84861893409
-
Notch controls the magnitude of T helper cell responses by promoting cellular longevity
-
Helbig C, Gentek R, Backer RA, de Souza Y, Derks IA, Eldering E et al. Notch controls the magnitude of T helper cell responses by promoting cellular longevity. Proc Natl Acad Sci USA 2012; 109: 9041-9046.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 9041-9046
-
-
Helbig, C.1
Gentek, R.2
Backer, R.A.3
De Souza, Y.4
Derks, I.A.5
Eldering, E.6
-
27
-
-
34447642439
-
Notch Directly Regulates Gata3 Expression during T Helper 2 Cell Differentiation
-
DOI 10.1016/j.immuni.2007.04.018, PII S107476130700338X
-
Fang TC, Yashiro-Ohtani Y, Del Bianco C, Knoblock DM, Blacklow SC, Pear WS. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 2007; 27: 100-110. (Pubitemid 47096803)
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 100-110
-
-
Fang, T.C.1
Yashiro-Ohtani, Y.2
Del Bianco, C.3
Knoblock, D.M.4
Blacklow, S.C.5
Pear, W.S.6
-
28
-
-
80053137239
-
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigenspecific CD8(+) T cells
-
Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE et al. Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigenspecific CD8(+) T cells. Immunity 2011; 35: 400-412.
-
(2011)
Immunity
, vol.35
, pp. 400-412
-
-
Youngblood, B.1
Oestreich, K.J.2
Ha, S.J.3
Duraiswamy, J.4
Akondy, R.S.5
West, E.E.6
-
29
-
-
17844402720
-
Integration of notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control
-
DOI 10.1016/j.devcel.2005.02.016, PII S1534580705000948
-
Mammucari C, Tommasi di Vignano A, Sharov AA, Neilson J, Havrda MC, Roop DR et al. Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Dev Cell 2005; 8: 665-676. (Pubitemid 40585290)
-
(2005)
Developmental Cell
, vol.8
, Issue.5
, pp. 665-676
-
-
Mammucari, C.1
Di Vignano, A.T.2
Sharov, A.A.3
Neilson, J.4
Havrda, M.C.5
Roop, D.R.6
Botchkarev, V.A.7
Crabtree, G.R.8
Dotto, G.P.9
-
30
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
DOI 10.1016/0092-8674(94)90169-4
-
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. T cell receptor antagonist peptides induce positive selection. Cell 1994; 76: 17-27. (Pubitemid 24035278)
-
(1994)
Cell
, vol.76
, Issue.1
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
31
-
-
0035348246
-
Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
-
van Stipdonk MJ, Lemmens EE, Schoenberger SP. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat Immunol 2001; 2: 423-429. (Pubitemid 33706140)
-
(2001)
Nature Immunology
, vol.2
, Issue.5
, pp. 423-429
-
-
Van Stipdonk, M.J.B.1
Lemmens, E.E.2
Schoenberger, S.P.3
-
32
-
-
36348991440
-
+ memory T cell accumulation
-
DOI 10.1002/eji.200637017
-
Allard EL, Hardy MP, Leignadier J, Marquis M, Rooney J, Lehoux D et al. Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation. Eur J Immunol 2007; 37: 3069-3077. (Pubitemid 350138977)
-
(2007)
European Journal of Immunology
, vol.37
, Issue.11
, pp. 3069-3077
-
-
Allard, E.-L.1
Hardy, M.-P.2
Leignadier, J.3
Marquis, M.4
Rooney, J.5
Lehoux, D.6
Labrecque, N.7
-
33
-
-
78149420281
-
Epitope density influences CD8 memory T cell differentiation
-
Leignadier J, Labrecque N. Epitope density influences CD8 memory T cell differentiation. PLoS One 2010; 5: E13740.
-
(2010)
PLoS One
, vol.5
-
-
Leignadier, J.1
Labrecque, N.2
|