Heparan sulfate proteoglycans are important for islet amyloid formation and islet amyloid polypeptide-induced apoptosis

Journal of Biological Chemistry

Volumn 290, Issue 24, 2015, Pages 15121-15132

  Oskarsson, Marie E ^a   Singh, Kailash ^a   Wang, Jian ^a,b   Vlodavsky, Israel ^c   Li, Jin Ping ^a   Westermark, Gunilla T ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Ningxia People's Hospital   (China)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; CELLS; CYTOLOGY; ENZYME ACTIVITY; HYDRAULIC STRUCTURES; MAMMALS; MOBILE SECURITY; SULFUR COMPOUNDS;

AMYLOID DEPOSITS; AMYLOID FORMATION; CASPASE-3 ACTIVATION; CONFORMATIONAL CHANGE; HEPARAN SULFATE PROTEOGLYCANS; INDUCED APOPTOSIS; ISLET AMYLOID POLYPEPTIDES; THERAPEUTIC TARGETS;

GLYCOPROTEINS;

AMYLIN; CASPASE 3; PROTEOHEPARAN SULFATE; AMYLOID; BETA GLUCURONIDASE; HEPARANASE; PRIMER DNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHO CELL LINE; CRICETULUS; ENZYMOLOGY; HAMSTER; METABOLISM; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

MUS MUSCULUS;

AMYLOID; ANIMALS; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; DNA PRIMERS; GLUCURONIDASE; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; ISLET AMYLOID POLYPEPTIDE; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84931260240     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.631697     Document Type: Article

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