Overexpression of human amyloidogenic light chains causes heart failure in embryonic zebrafish: A preliminary report

Amyloid

Volumn 19, Issue 4, 2012, Pages 191-196

  Shin, Jordan T ^a   Ward, Jennifer E ^b   Collins, Patricia A ^a   Dai, Matthew ^a   Semigran, Hannah L ^a   Semigran, Marc J ^a   Seldin, David C ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloidosis; Animal models; Heart failure; Zebrafish

Indexed keywords

AMYLOID; AMYLOID PROTEIN; MESSENGER RNA;

ANIMAL TISSUE; AQUACULTURE; ARTICLE; CARDIOMYOPATHY; CARDIOTOXICITY; CLINICAL FEATURE; EDEMA; EMBRYO; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART DISEASE; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIGHT CHAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; ZEBRA FISH;

AMYLOIDOGENIC PROTEINS; AMYLOIDOSIS; ANIMALS; CARDIOMYOPATHIES; DISEASE MODELS, ANIMAL; EMBRYO, NONMAMMALIAN; GENE EXPRESSION; HEART FAILURE; HEART VENTRICLES; HUMANS; MICROINJECTIONS; MYOCARDIUM; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RNA, MESSENGER; ZEBRAFISH; ZYGOTE;

EID: 84868358491     PISSN: 13506129     EISSN: 17442818     Source Type: Journal    
DOI: 10.3109/13506129.2012.733741     Document Type: Article

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