Processing and activation of latent heparanase occurs in lysosomes

Journal of Cell Science

Volumn 117, Issue 11, 2004, Pages 2249-2258

  Zetser, Anna ^a   Levy Adam, Flonia ^a   Kaplan, Victoria ^a   Gingis Velitski, Svetlana ^a   Bashenko, Yulia ^a   Schubert, Shay ^a   Flugelman, Moshe Y ^b   Vlodavsky, Israel ^a   Ilan, Neta ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b CARMEL MEDICAL CENTER   (Israel)

Author keywords

Antibody; Heparanase; Localization; Lysosome; Processing; Uptake

Indexed keywords

BAFILOMYCIN A1; CHLOROQUINE; ENZYME ANTIBODY; ENZYME PRECURSOR; GLYCOSIDASE; HEPARAN SULFATE; HEPARANASE; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; PROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DEGRADATION; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME LOCALIZATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LYSOSOME; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TRANSPORT;

ANIMALS; ANTIBODIES; CELL LINE, TUMOR; CHLOROQUINE; CHO CELLS; CRICETINAE; ENZYME ACTIVATION; GLUCURONIDASE; HUMANS; HYDROLYSIS; LYSOSOMES; MACROLIDES; PROTEASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; TRANSFECTION;

ANIMALIA;

EID: 3042637381     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01068     Document Type: Article

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