Contribution of sodium channels to lamellipodial protrusion and Rac1 and ERK1/2 activation in ATP-stimulated microglia

GLIA

Volumn 62, Issue 12, 2014, Pages 2080-2095

  Persson, Anna Karin ^a,b   Estacion, Mark ^a,b   Ahn, Hyesook ^a,b   Liu, Shujun ^a,b   Stamboulian Platel, Severine ^a,b   Waxman, Stephen G ^a,b   Black, Joel A ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Lamellipodia; Membrane ruffling; Microglia; Neuroinflammation; Sodium channels

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHALLOIDIN; RAC1 PROTEIN; SODIUM CHANNEL; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.6; ENZYME INHIBITOR; SCN8A PROTEIN, MOUSE; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOCYTOCHEMISTRY; LAMELLIPODIUM; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; ANIMAL; BRAIN; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MEMBRANE POTENTIAL; METABOLISM; MOUSE; NEWBORN; PHYSIOLOGY; PSEUDOPODIUM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TRANSGENIC MOUSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL MOVEMENT; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE 3; NAV1.6 VOLTAGE-GATED SODIUM CHANNEL; PSEUDOPODIA; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SODIUM CHANNEL BLOCKERS;

EID: 84931084606     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22728     Document Type: Article

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