메뉴 건너뛰기




Volumn 49, Issue 2, 2005, Pages 220-229

Sodium channels contribute to microglia/macrophage activation and function in EAE and MS

Author keywords

EAE; Macrophages; Microglia; MS; Nav1.6

Indexed keywords

PHENYTOIN; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

EID: 13244258365     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.20112     Document Type: Article
Times cited : (224)

References (55)
  • 3
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
    • Barnett MH, Prineas JW. 2004. Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion. Ann Neurol 55:458-468.
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 4
    • 0033104019 scopus 로고    scopus 로고
    • Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor
    • Batchelor PE, Liberatore GT, Wong JY, Porritt MJ, Frerichs F, Donnan GA, Howells DW. 1999. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J Neurosci 19:1708-1716.
    • (1999) J Neurosci , vol.19 , pp. 1708-1716
    • Batchelor, P.E.1    Liberatore, G.T.2    Wong, J.Y.3    Porritt, M.J.4    Frerichs, F.5    Donnan, G.A.6    Howells, D.W.7
  • 5
    • 0029451821 scopus 로고
    • The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis
    • Bauer J, Huitinga I, Zhao W, Lassmann H, Hickey WF, Dijkstra CD. 1995. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia 15:437-446.
    • (1995) Glia , vol.15 , pp. 437-446
    • Bauer, J.1    Huitinga, I.2    Zhao, W.3    Lassmann, H.4    Hickey, W.F.5    Dijkstra, C.D.6
  • 6
    • 2142760098 scopus 로고    scopus 로고
    • Axonal protection mediated by flecainide therapy in experimental inflammatory demyelinating disease
    • Bechtold DA, Kapoor R, Smith KJ. 2004. Axonal protection mediated by flecainide therapy in experimental inflammatory demyelinating disease. Ann Neurol 55:607-616.
    • (2004) Ann Neurol , vol.55 , pp. 607-616
    • Bechtold, D.A.1    Kapoor, R.2    Smith, K.J.3
  • 8
    • 0027583585 scopus 로고
    • Spinal cord astrocytes in vitro: Phenotypic diversity and sodium channel immunoreactivity
    • Black JA, Sontheimer H, Waxman SG. 1993. Spinal cord astrocytes in vitro: phenotypic diversity and sodium channel immunoreactivity. Glia 7:272-285.
    • (1993) Glia , vol.7 , pp. 272-285
    • Black, J.A.1    Sontheimer, H.2    Waxman, S.G.3
  • 10
    • 0038233014 scopus 로고    scopus 로고
    • Nitric oxide-mediated mitochondrial damage in the brain: Mechanisms and implications for neurodegenerative diseases
    • Bolanos JP, Almeida A, Stewart V, Peuchen S, Land JM, Clark JB, Heales SJ. 1997. Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases. J Neurochem 68:2227-2240.
    • (1997) J Neurochem , vol.68 , pp. 2227-2240
    • Bolanos, J.P.1    Almeida, A.2    Stewart, V.3    Peuchen, S.4    Land, J.M.5    Clark, J.B.6    Heales, S.J.7
  • 11
    • 0019468319 scopus 로고
    • The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis
    • Brosnan CF, Bornstein MB, Bloom BR. 1981. The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis. J Immunol 126:614-620.
    • (1981) J Immunol , vol.126 , pp. 614-620
    • Brosnan, C.F.1    Bornstein, M.B.2    Bloom, B.R.3
  • 12
    • 0027970495 scopus 로고
    • + T lymphocytes in the central nervous system
    • + T lymphocytes in the central nervous system. Clin Exp Immunol 98:313-318.
    • (1994) Clin Exp Immunol , vol.98 , pp. 313-318
    • Cash, E.1    Rott, O.2
  • 13
    • 0029051044 scopus 로고
    • + current of mammalian CNS neurones
    • + current of mammalian CNS neurones. NeuroReport 6:1778-1780.
    • (1995) NeuroReport , vol.6 , pp. 1778-1780
    • Chao, T.I.1    Alzheimer, C.2
  • 15
    • 0742305831 scopus 로고    scopus 로고
    • v1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE
    • v1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain 127(Pt 2):294-303.
    • (2004) Brain , vol.127 , Issue.PART 2 , pp. 294-303
    • Craner, M.J.1    Hains, B.C.2    Lo, A.C.3    Black, J.A.4    Waxman, S.G.5
  • 17
    • 0034648738 scopus 로고    scopus 로고
    • Neuropeptides in hippocampus and cortex in transgenic mice overexpressing V717F beta-amyloid precursor protein - Initial observations
    • Diez M, Koistinaho J, Kahn K, Games D, Hokfelt T. 2000. Neuropeptides in hippocampus and cortex in transgenic mice overexpressing V717F beta-amyloid precursor protein-initial observations. Neuroscience 100:259-286.
    • (2000) Neuroscience , vol.100 , pp. 259-286
    • Diez, M.1    Koistinaho, J.2    Kahn, K.3    Games, D.4    Hokfelt, T.5
  • 18
    • 0033460317 scopus 로고    scopus 로고
    • Morphological, immunophenotypical and electrophysiological properties of resting microglia in vitro
    • Eder C, Schilling T, Heinemann U, Haas D, Hailer N, Nitsch R. 1999. Morphological, immunophenotypical and electrophysiological properties of resting microglia in vitro. Eur J Neurosci 11:4251-4261.
    • (1999) Eur J Neurosci , vol.11 , pp. 4251-4261
    • Eder, C.1    Schilling, T.2    Heinemann, U.3    Haas, D.4    Hailer, N.5    Nitsch, R.6
  • 19
    • 0020541216 scopus 로고
    • Concanavalin A causes an increase in sodium permeability and intracellular sodium content of pig lymphocytes
    • Felber SM, Brand MD. 1983. Concanavalin A causes an increase in sodium permeability and intracellular sodium content of pig lymphocytes. Biochem J 210:893-897.
    • (1983) Biochem J , vol.210 , pp. 893-897
    • Felber, S.M.1    Brand, M.D.2
  • 20
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, Esiri MM, Perry VH. 1997. Axonal damage in acute multiple sclerosis lesions. Brain 120:393-399.
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 23
    • 0037110631 scopus 로고    scopus 로고
    • Primary motor neurons fail to up-regulate voltage-gated sodium channel Na(v)1.3/brain type III following axotomy resulting from spinal cord injury
    • Hains BC, Black JA, Waxman SG. 2002. Primary motor neurons fail to up-regulate voltage-gated sodium channel Na(v)1.3/brain type III following axotomy resulting from spinal cord injury. J Neurosci Res 70:546-552.
    • (2002) J Neurosci Res , vol.70 , pp. 546-552
    • Hains, B.C.1    Black, J.A.2    Waxman, S.G.3
  • 25
    • 0038795206 scopus 로고    scopus 로고
    • Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): Suppression of receptor-evoked calcium signaling and control of release function
    • Hoffmann A, Kann O, Ohlemeyer C, Hanisch UK, Kettenmann H. 2003. Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function. J Neurosci 23:4410-4419.
    • (2003) J Neurosci , vol.23 , pp. 4410-4419
    • Hoffmann, A.1    Kann, O.2    Ohlemeyer, C.3    Hanisch, U.K.4    Kettenmann, H.5
  • 26
    • 0030982181 scopus 로고    scopus 로고
    • Mitochondrial regulation of store-operated calcium signaling in T lymphocytes
    • Hoth M, Fanger CM, Lewis RS. 1997. Mitochondrial regulation of store-operated calcium signaling in T lymphocytes. J Cell Biol 137:633-648.
    • (1997) J Cell Biol , vol.137 , pp. 633-648
    • Hoth, M.1    Fanger, C.M.2    Lewis, R.S.3
  • 28
    • 0037309442 scopus 로고    scopus 로고
    • Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration
    • Kapoor R, Davies M, Blaker PA, Hall SM, Smith KJ. 2003. Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration. Ann Neurol 53:174-180.
    • (2003) Ann Neurol , vol.53 , pp. 174-180
    • Kapoor, R.1    Davies, M.2    Blaker, P.A.3    Hall, S.M.4    Smith, K.J.5
  • 29
    • 0030015959 scopus 로고    scopus 로고
    • Mutation detection in the med and medJ alleles of the sodium channel Scn8a. Unusual splicing due to a minor class AT-AC intron
    • Kohrman DC, Harris JB, Meisler MH. 1996. Mutation detection in the med and medJ alleles of the sodium channel Scn8a. Unusual splicing due to a minor class AT-AC intron. J Biol Chem 271:17576-17581.
    • (1996) J Biol Chem , vol.271 , pp. 17576-17581
    • Kohrman, D.C.1    Harris, J.B.2    Meisler, M.H.3
  • 30
    • 0033870097 scopus 로고    scopus 로고
    • Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
    • Kornek B, Storch MK, Weissert R, Wallstroem E, Stefferl A, Olsson T, Linington C, Schmidbauer M, Lassmann H. 2000. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am J Pathol 157:267-276.
    • (2000) Am J Pathol , vol.157 , pp. 267-276
    • Kornek, B.1    Storch, M.K.2    Weissert, R.3    Wallstroem, E.4    Stefferl, A.5    Olsson, T.6    Linington, C.7    Schmidbauer, M.8    Lassmann, H.9
  • 31
    • 0026685350 scopus 로고
    • Voltage-gated currents expressed by rat microglia in culture
    • Korotzer AR, Cotman CW. 1992. Voltage-gated currents expressed by rat microglia in culture. Glia 6:81-88.
    • (1992) Glia , vol.6 , pp. 81-88
    • Korotzer, A.R.1    Cotman, C.W.2
  • 32
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 33
    • 0029948229 scopus 로고    scopus 로고
    • Microglia-derived macrophages in early multiple sclerosis plaques
    • Li H, Cuzner ML, Newcombe J. 1996. Microglia-derived macrophages in early multiple sclerosis plaques. Neuropathol Appl Neurobiol 22:207-215.
    • (1996) Neuropathol Appl Neurobiol , vol.22 , pp. 207-215
    • Li, H.1    Cuzner, M.L.2    Newcombe, J.3
  • 34
    • 0037191415 scopus 로고    scopus 로고
    • Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis
    • Lo AC, Black JA, Waxman SG. 2002. Neuroprotection of axons with phenytoin in experimental allergic encephalomyelitis. NeuroReport 13:1909-1912.
    • (2002) NeuroReport , vol.13 , pp. 1909-1912
    • Lo, A.C.1    Black, J.A.2    Waxman, S.G.3
  • 35
    • 0242508548 scopus 로고    scopus 로고
    • Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo
    • Lo AC, Saab CY, Black JA, Waxman SG. 2003. Phenytoin protects spinal cord axons and preserves axonal conduction and neurological function in a model of neuroinflammation in vivo. J Neurophysiol 90:3566-3571.
    • (2003) J Neurophysiol , vol.90 , pp. 3566-3571
    • Lo, A.C.1    Saab, C.Y.2    Black, J.A.3    Waxman, S.G.4
  • 36
    • 0026628844 scopus 로고
    • Immune regulation by brain cells in the central nervous system: Microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions
    • Matsumoto Y, Ohmori K, Fujiwara M. 1992. Immune regulation by brain cells in the central nervous system: microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions. Immunology 76:209-216.
    • (1992) Immunology , vol.76 , pp. 209-216
    • Matsumoto, Y.1    Ohmori, K.2    Fujiwara, M.3
  • 37
    • 0028061167 scopus 로고
    • Nitric oxide as a potential pathological mechanism in demyelination: Its differential effects on primary glial cells in vitro
    • Mitrovic B, Ignarro LJ, Montestruque S, Smoll A, Merrill JE. 1994. Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro. Neuroscience 61:575-585.
    • (1994) Neuroscience , vol.61 , pp. 575-585
    • Mitrovic, B.1    Ignarro, L.J.2    Montestruque, S.3    Smoll, A.4    Merrill, J.E.5
  • 38
    • 0027337420 scopus 로고
    • Organization and research applications of the U.K.
    • Multiple Sclerosis Society Tissue Bank
    • Newcombe J, Cuzner ML. 1993. Organization and research applications of the U.K. Multiple Sclerosis Society Tissue Bank. J Neural Transm 39(suppl):155-163.
    • (1993) J Neural Transm , vol.39 , Issue.SUPPL. , pp. 155-163
    • Newcombe, J.1    Cuzner, M.L.2
  • 39
    • 0028397869 scopus 로고
    • Sodium channels in isolated human brain macrophages (microglia)
    • Norenberg W, Illes P, Gebicke-Haerter PJ. 1994. Sodium channels in isolated human brain macrophages (microglia). Glia 10:165-172.
    • (1994) Glia , vol.10 , pp. 165-172
    • Norenberg, W.1    Illes, P.2    Gebicke-Haerter, P.J.3
  • 40
    • 0023145148 scopus 로고
    • Sodium ion influx in proliferating lymphocytes: An early component of the mitogenic signal
    • Prasad KV, Severini A, Kaplan JG. 1987. Sodium ion influx in proliferating lymphocytes: an early component of the mitogenic signal. Arch Biochem Biophys 252:515-525.
    • (1987) Arch Biochem Biophys , vol.252 , pp. 515-525
    • Prasad, K.V.1    Severini, A.2    Kaplan, J.G.3
  • 41
    • 0344407029 scopus 로고    scopus 로고
    • Microglial changes accompanying the promotion of retinal ganglion cell axonal regeneration into peripheral nerve grafts
    • Raibon E, Sauve Y, Carter DA, Gaillard F. 2002. Microglial changes accompanying the promotion of retinal ganglion cell axonal regeneration into peripheral nerve grafts. J Neurocytol 31:57-71.
    • (2002) J Neurocytol , vol.31 , pp. 57-71
    • Raibon, E.1    Sauve, Y.2    Carter, D.A.3    Gaillard, F.4
  • 42
    • 0028983573 scopus 로고
    • TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines
    • Renno T, Krakowski M, Piccirillo C, Lin JY, Owens T. 1995. TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines. J Immunol 154:944-953.
    • (1995) J Immunol , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.Y.4    Owens, T.5
  • 43
    • 0033565856 scopus 로고    scopus 로고
    • Effects of the sodium channel blocker tetrodotoxin on acute white matter pathology after experimental contusive spinal cord injury
    • Rosenberg LJ, Teng YD, Wrathall JR. 1999. Effects of the sodium channel blocker tetrodotoxin on acute white matter pathology after experimental contusive spinal cord injury. J Neurosci 19:6122-6133.
    • (1999) J Neurosci , vol.19 , pp. 6122-6133
    • Rosenberg, L.J.1    Teng, Y.D.2    Wrathall, J.R.3
  • 44
    • 0344013138 scopus 로고    scopus 로고
    • High-yield isolation of murine microglia by mild trypsinization
    • Saura J, Tusell JM, Serratosa J. 2003. High-yield isolation of murine microglia by mild trypsinization. Glia 44:183-189.
    • (2003) Glia , vol.44 , pp. 183-189
    • Saura, J.1    Tusell, J.M.2    Serratosa, J.3
  • 45
    • 0028675515 scopus 로고
    • Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: Membrane currents
    • Schmidtmayer J, Jacobsen C, Miksch G, Sievers J. 1994. Blood monocytes and spleen macrophages differentiate into microglia-like cells on monolayers of astrocytes: membrane currents. Glia 12:259-267.
    • (1994) Glia , vol.12 , pp. 259-267
    • Schmidtmayer, J.1    Jacobsen, C.2    Miksch, G.3    Sievers, J.4
  • 46
    • 0025900245 scopus 로고
    • Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system
    • Sedgwick JD, Schwender S, Imrich H, Dorries R, Butcher GW, ter Meulen V. 1991. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc Natl Acad Sci USA 88:7438-7442.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7438-7442
    • Sedgwick, J.D.1    Schwender, S.2    Imrich, H.3    Dorries, R.4    Butcher, G.W.5    Ter Meulen, V.6
  • 47
    • 0030857906 scopus 로고    scopus 로고
    • Late sodium channel openings underlying epileptiform activity are preferentially diminished by the anticonvulsant phenytoin
    • Segal MM, Douglas AF. 1997. Late sodium channel openings underlying epileptiform activity are preferentially diminished by the anticonvulsant phenytoin. J Neurophysiol 77:3021-3034.
    • (1997) J Neurophysiol , vol.77 , pp. 3021-3034
    • Segal, M.M.1    Douglas, A.F.2
  • 49
    • 0030966265 scopus 로고    scopus 로고
    • Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons
    • Stys PK, Lopachin RM. 1998. Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons. Neuroscience 82:21-32.
    • (1998) Neuroscience , vol.82 , pp. 21-32
    • Stys, P.K.1    Lopachin, R.M.2
  • 50
    • 0026599820 scopus 로고
    • Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability
    • Stys PK, Ransom BR, Waxman SG. 1992a. Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability. J Neurophysiol 67:236-240.
    • (1992) J Neurophysiol , vol.67 , pp. 236-240
    • Stys, P.K.1    Ransom, B.R.2    Waxman, S.G.3
  • 54
    • 0032576636 scopus 로고    scopus 로고
    • Demyelinating diseases - New pathological insights, new therapeutic targets
    • Waxman SG. 1998. Demyelinating diseases-new pathological insights, new therapeutic targets. N Engl J Med 338:323-325.
    • (1998) N Engl J Med , vol.338 , pp. 323-325
    • Waxman, S.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.