Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Kelley, Laura C ^a   Hayes, Karen E ^a   Ammer, Amanda Gatesman ^a   Martin, Karen H ^a   Weed, Scott A ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CORTACTIN; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SERINE; TYROSINE; CTTN PROTEIN, HUMAN; GREEN FLUORESCENT PROTEIN; MAPK1 PROTEIN, HUMAN; WISKOTT ALDRICH SYNDROME PROTEIN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; CANCER INVASION; CARCINOMA CELL; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LAMELLIPODIUM; MICROSCOPY; NONHUMAN; POINT MUTATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; WESTERN BLOTTING; CELL MOTION; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; MOLECULAR DYNAMICS; NEOPLASM; PATHOLOGY; PHOSPHORYLATION; PROTEIN CONFORMATION; PSEUDOPODIUM; RNA INTERFERENCE; TUMOR CELL LINE;

ACTINS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CORTACTIN; EPIDERMAL GROWTH FACTOR; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR DYNAMICS SIMULATION; NEOPLASMS; PHOSPHORYLATION; PROTEIN CONFORMATION; PSEUDOPODIA; RNA INTERFERENCE; SERINE; TYROSINE; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 78649696631     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013847     Document Type: Article

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