Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

Journal of Cell Science

Volumn 126, Issue 20, 2013, Pages 4572-4588

  Steffen, Anika ^a   Ladwein, Markus ^b   Dimchev, Georgi A ^a   Hein, Anke ^a   Schwenkmezger, Lisa ^a   Arens, Stefan ^c   Ladwein, Kathrin I ^b   Holleboom, J Margit ^a,b   Schur, Florian ^d   Small, J Victor ^d   Schwarz, Janett ^e   Gerhard, Ralf ^e   Faix, Jan ^e   Stradal, Theresia E B ^b,c   Brakebusch, Cord ^f   Rottner, Klemens ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Actin; Adhesion; CAAX; Chemotaxis; Filopodia; Lamellipodia; Migration; Rac1

Indexed keywords

RAC PROTEIN; RAC1 PROTEIN; RAC2 PROTEIN; RAC3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL SPREADING; CONTROLLED STUDY; EMBRYO; FIBROBLAST CULTURE; FILOPODIUM; FOCAL ADHESION; LAMELLIPODIUM; MOUSE; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; WOUND CLOSURE;

ACTIN; ADHESION; CAAX; CHEMOTAXIS; FILOPODIA; LAMELLIPODIA; MIGRATION; RAC1;

ACTINS; ANIMALS; CELL MOVEMENT; FIBROBLASTS; FOCAL ADHESIONS; MICE, TRANSGENIC; NEUROPEPTIDES; PSEUDOPODIA; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84885454469     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.118232     Document Type: Article

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