Voltage-gated sodium channel Nav1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na+/Ca2+ exchange

GLIA

Volumn 62, Issue 7, 2014, Pages 1162-1175

  Pappalardo, Laura W ^a,b   Samad, Omar A ^a,b   Black, Joel A ^a,b   Waxman, Stephen G ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Glial scar; Migration; Proliferation; Sodium channels; Sodium calcium exchanger

Indexed keywords

2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; SMALL INTERFERING RNA; SODIUM CHANNEL NAV1.5; TETRODOTOXIN; 2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; CALCIUM; MESSENGER RNA; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CHANNEL BLOCKING AGENT; SODIUM-CALCIUM EXCHANGER 1; THIOUREA;

ANIMAL CELL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL DAMAGE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; GENE SILENCING; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM CALCIUM EXCHANGE; TREATMENT RESPONSE; WOUND CLOSURE; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CORTEX; CELL CULTURE; CELL MOTION; DRUG EFFECTS; GENETICS; GLIOSIS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STIMULATION; WOUND HEALING; WOUNDS AND INJURIES;

ANIMALS; ASTROCYTES; CALCIUM; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL CORTEX; GENE KNOCKDOWN TECHNIQUES; GLIOSIS; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PHYSICAL STIMULATION; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SODIUM CHANNEL BLOCKERS; SODIUM-CALCIUM EXCHANGER; TETRODOTOXIN; THIOUREA; WOUND HEALING; WOUNDS AND INJURIES;

EID: 84900821848     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22671     Document Type: Article

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