Involvement of caspase-3 activity and survivin downregulation in cinobufocini-induced apoptosis in A 549 cells

Experimental Biology and Medicine

Volumn 234, Issue 5, 2009, Pages 566-572

  Wang, Juyong ^a   Jin, Ye ^b   Xu, Zhenye ^a   Zheng, Zhan ^a   Wan, Su ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b SHANGHAI UNIVERSITY   (China)

Author keywords

A 549 cell; Apoptosis; Caspase 3; Cinobufocini injection; Survivin

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CINOBUFOCINI; MESSENGER RNA; SURVIVIN; UNCLASSIFIED DRUG; BIRC5 PROTEIN, HUMAN; BUFADIENOLIDE DERIVATIVE; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL LINE; CELL PROLIFERATION; CELL STRAIN A 549; CELL STRUCTURE; COLORIMETRY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FETUS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG FIBROBLAST; NITROBLUE TETRAZOLIUM TEST; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPE; STAINING; TUMOR GROWTH; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; CHAN SU; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; TUMOR CELL LINE;

ANURA;

APOPTOSIS; BUFANOLIDES; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG SCREENING ASSAYS, ANTITUMOR; G1 PHASE; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; S PHASE; UP-REGULATION;

EID: 66149145921     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0811-RM-326     Document Type: Article

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