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Volumn 183, Issue 11, 2007, Pages 593-599

The role of survivin for radiation therapy: Prognostic and predictive factor and therapeutic target

Author keywords

Apoptosis; Radiooncology; Survivin; Therapeutic target

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; RIBOZYME; SMALL INTERFERING RNA; SURVIVIN;

EID: 36248971578     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00066-007-1800-4     Document Type: Review
Times cited : (62)

References (65)
  • 1
    • 0037267333 scopus 로고    scopus 로고
    • Validating survivin as a cancer therapeutic target
    • Altieri DC. Validating survivin as a cancer therapeutic target. Nat Rev Cancer 2003;3:46-54.
    • (2003) Nat Rev Cancer , vol.3 , pp. 46-54
    • Altieri, D.C.1
  • 2
    • 0030746636 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
    • Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997;3:917-21.
    • (1997) Nat Med , vol.3 , pp. 917-921
    • Ambrosini, G.1    Adida, C.2    Altieri, D.C.3
  • 3
    • 0033637762 scopus 로고    scopus 로고
    • Survivin as a radioresistance factor in pancreatic cancer
    • Asanuma K, Moriai R, Yajima T, et al. Survivin as a radioresistance factor in pancreatic cancer. Jpn J Cancer Res 2000;91:1204-9.
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1204-1209
    • Asanuma, K.1    Moriai, R.2    Yajima, T.3
  • 4
    • 33846020971 scopus 로고    scopus 로고
    • Survivin protein expression and hypoxia in advanced cervical carcinoma of patients treated by radiotherapy
    • Bache M, Holzapfel D, Kappler M, et al. Survivin protein expression and hypoxia in advanced cervical carcinoma of patients treated by radiotherapy. Gynecol Oncol 2007;104:139-44.
    • (2007) Gynecol Oncol , vol.104 , pp. 139-144
    • Bache, M.1    Holzapfel, D.2    Kappler, M.3
  • 5
    • 1642578958 scopus 로고    scopus 로고
    • Identification of a novel splice variant of the human anti-apoptopsis gene survivin
    • Badran A, Yoshida A, Ishikawa K, et al. Identification of a novel splice variant of the human anti-apoptopsis gene survivin. Biochem Biophys Res Commun 2004;314:902-7.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 902-907
    • Badran, A.1    Yoshida, A.2    Ishikawa, K.3
  • 6
    • 33747067724 scopus 로고    scopus 로고
    • Combined effect of tumor necrosis factor-alpha and ionizing radiation on the induction of apoptosis in 5637 bladder carcinoma cells
    • Baierlein SA, Distel L, Sieber R, et al. Combined effect of tumor necrosis factor-alpha and ionizing radiation on the induction of apoptosis in 5637 bladder carcinoma cells. Strahlenther Onkol 2006;182:467-72.
    • (2006) Strahlenther Onkol , vol.182 , pp. 467-472
    • Baierlein, S.A.1    Distel, L.2    Sieber, R.3
  • 7
    • 0034554738 scopus 로고    scopus 로고
    • Survivin does not inhibit caspase-3 activity
    • Banks DP, Plescia J, Altieri DC, et al. Survivin does not inhibit caspase-3 activity. Blood 2000;96:4002-3.
    • (2000) Blood , vol.96 , pp. 4002-4003
    • Banks, D.P.1    Plescia, J.2    Altieri, D.C.3
  • 8
    • 17044372038 scopus 로고    scopus 로고
    • Radiosensitivity of Tumor Cell Lines after Pretreatment with the EGFR Tyrosine Kinase Inhibitor ZD1839 (Iressa®)
    • Burdak-Rothkamm S, Rube CE, Nguyen TP, et al. Radiosensitivity of Tumor Cell Lines after Pretreatment with the EGFR Tyrosine Kinase Inhibitor ZD1839 (Iressa®). Strahlenther Onkol 2005;181:197-204.
    • (2005) Strahlenther Onkol , vol.181 , pp. 197-204
    • Burdak-Rothkamm, S.1    Rube, C.E.2    Nguyen, T.P.3
  • 9
    • 22144438181 scopus 로고    scopus 로고
    • Survivin 2alpha: A novel Survivin splice variant expressed in human malignancies
    • Caldas H, Honsey LE , Altura RA. Survivin 2alpha: a novel Survivin splice variant expressed in human malignancies. Mol Cancer 2005;4:11.
    • (2005) Mol Cancer , vol.4 , pp. 11
    • Caldas, H.1    Honsey, L.E.2    Altura, R.A.3
  • 10
    • 4844231863 scopus 로고    scopus 로고
    • XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer
    • Cao C, Mu Y, Hallahan DE, et al. XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer. Oncogene 2004;23:7047-52.
    • (2004) Oncogene , vol.23 , pp. 7047-7052
    • Cao, C.1    Mu, Y.2    Hallahan, D.E.3
  • 11
    • 6344261577 scopus 로고    scopus 로고
    • Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms
    • Chakravarti A, Zhai GG, Zhang M, et al. Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms. Oncogene 2004;23:7494-506.
    • (2004) Oncogene , vol.23 , pp. 7494-7506
    • Chakravarti, A.1    Zhai, G.G.2    Zhang, M.3
  • 12
    • 9144247196 scopus 로고    scopus 로고
    • Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth
    • Chen J, Wu W, Tahir SK, et al. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia 2000;2:235-41.
    • (2000) Neoplasia , vol.2 , pp. 235-241
    • Chen, J.1    Wu, W.2    Tahir, S.K.3
  • 13
    • 33845929217 scopus 로고    scopus 로고
    • Separating the anti-apoptotic and mitotic roles of survivin
    • Colnaghi R, Connell CM, Barrett RM, et al. Separating the anti-apoptotic and mitotic roles of survivin. J Biol Chem 2006;281:33450-06.
    • (2006) J Biol Chem , vol.281 , pp. 33450-33406
    • Colnaghi, R.1    Connell, C.M.2    Barrett, R.M.3
  • 14
    • 4544261227 scopus 로고    scopus 로고
    • An IAP-IAP complex inhibits apoptosis
    • Dohi T, Okada K, Xia F, et al. An IAP-IAP complex inhibits apoptosis. J Biol Chem 2004;279:34087-90.
    • (2004) J Biol Chem , vol.279 , pp. 34087-34090
    • Dohi, T.1    Okada, K.2    Xia, F.3
  • 15
    • 0036472994 scopus 로고    scopus 로고
    • Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function
    • Fortugno P, Wall NR, Giodini A, et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci 2002;115:575-85.
    • (2002) J Cell Sci , vol.115 , pp. 575-585
    • Fortugno, P.1    Wall, N.R.2    Giodini, A.3
  • 17
    • 33846630796 scopus 로고    scopus 로고
    • High survivin expression is associated with favorable outcome in advanced primary oral squamous cell carcinoma after radiation therapy
    • Freier K, Pungs S, Sticht C, et al. High survivin expression is associated with favorable outcome in advanced primary oral squamous cell carcinoma after radiation therapy. Int J Cancer 2007;120:942-6.
    • (2007) Int J Cancer , vol.120 , pp. 942-946
    • Freier, K.1    Pungs, S.2    Sticht, C.3
  • 18
    • 0035496913 scopus 로고    scopus 로고
    • Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: Implication of survivin expression in normal hematopoiesis
    • Fukuda S, Pelus LM. Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis. Blood 2001;98:2091-100.
    • (2001) Blood , vol.98 , pp. 2091-2100
    • Fukuda, S.1    Pelus, L.M.2
  • 19
    • 33745087154 scopus 로고    scopus 로고
    • Survivin, a cancer target with an emerging role in normal adult tissues
    • Fukuda S , Pelus LM. Survivin, a cancer target with an emerging role in normal adult tissues. Mol Cancer Ther 2006;5:1087-98.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1087-1098
    • Fukuda, S.1    Pelus, L.M.2
  • 20
    • 30344487247 scopus 로고    scopus 로고
    • Reoxygenation of human coronary smooth muscle cells suppresses HIF-1alpha gene expression and augments radiation-induced growth delay and apoptosis
    • Grumann T, Arab A, Bode C, et al. Reoxygenation of human coronary smooth muscle cells suppresses HIF-1alpha gene expression and augments radiation-induced growth delay and apoptosis. Strahlenther Onkol 2006;182:16-21.
    • (2006) Strahlenther Onkol , vol.182 , pp. 16-21
    • Grumann, T.1    Arab, A.2    Bode, C.3
  • 21
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D , Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 22
    • 34547126428 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) as cancer targets
    • Hunter AM, Lacasse EC , Korneluk RG. The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 2007;12:1543-68.
    • (2007) Apoptosis , vol.12 , pp. 1543-1568
    • Hunter, A.M.1    Lacasse, E.C.2    Korneluk, R.G.3
  • 23
    • 34249941557 scopus 로고    scopus 로고
    • Purvalanol A enhances cell killing by inhibiting up-regulation of CDC2 kinase activity in tumor cells irradiated with high doses of X rays
    • Iizuka D, Inanami O, Kashiwakura I, et al. Purvalanol A enhances cell killing by inhibiting up-regulation of CDC2 kinase activity in tumor cells irradiated with high doses of X rays. Radiat Res 2007;167:563-71.
    • (2007) Radiat Res , vol.167 , pp. 563-571
    • Iizuka, D.1    Inanami, O.2    Kashiwakura, I.3
  • 24
    • 24344482906 scopus 로고    scopus 로고
    • Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells
    • Kami K, Doi R, Koizumi M, et al. Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells. Surgery 2005;138:299-305.
    • (2005) Surgery , vol.138 , pp. 299-305
    • Kami, K.1    Doi, R.2    Koizumi, M.3
  • 25
    • 10744227367 scopus 로고    scopus 로고
    • Knockdown of survivin expression by small interfering RNA reduces the clonogenic survival of human sarcoma cell lines independently of p53
    • Kappler M, Bache M, Bartel F, et al. Knockdown of survivin expression by small interfering RNA reduces the clonogenic survival of human sarcoma cell lines independently of p53. Cancer Gene Ther 2004;11:186-93.
    • (2004) Cancer Gene Ther , vol.11 , pp. 186-193
    • Kappler, M.1    Bache, M.2    Bartel, F.3
  • 26
    • 21644488884 scopus 로고    scopus 로고
    • Radiosensitization, after a combined treatment of survivin siRNA and irradiation, is correlated with the activation of caspases 3 and 7 in a wt-p53 sarcoma cell line, but not in a mt-p53 sarcoma cell line
    • Kappler M, Taubert H, Bartel F, et al. Radiosensitization, after a combined treatment of survivin siRNA and irradiation, is correlated with the activation of caspases 3 and 7 in a wt-p53 sarcoma cell line, but not in a mt-p53 sarcoma cell line. Oncol Rep 2005;13:167-72.
    • (2005) Oncol Rep , vol.13 , pp. 167-172
    • Kappler, M.1    Taubert, H.2    Bartel, F.3
  • 27
    • 36248944451 scopus 로고    scopus 로고
    • Knock down of survivin, survivin-2B or survivin-delta 3 in combination with irradiation affects clonogenic survival in a soft tissue sarcoma cell line under normoxic and hypoxic conditions
    • in press
    • Kappler M, Rot S, Taubert H, et al. Knock down of survivin, survivin-2B or survivin-delta 3 in combination with irradiation affects clonogenic survival in a soft tissue sarcoma cell line under normoxic and hypoxic conditions. Cancer Gene Ther 2007, in press.
    • (2007) Cancer Gene Ther
    • Kappler, M.1    Rot, S.2    Taubert, H.3
  • 28
    • 33947535689 scopus 로고    scopus 로고
    • Inhibition of survivin and aurora B kinase sensitizes mesothelioma cells by enhancing mitotic arrests
    • Kim KW, Mutter RW, Willey CD, et al. Inhibition of survivin and aurora B kinase sensitizes mesothelioma cells by enhancing mitotic arrests. Int J Radiat Oncol Biol Phys 2007;67:1519-25.
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 1519-1525
    • Kim, K.W.1    Mutter, R.W.2    Willey, C.D.3
  • 29
    • 0038498213 scopus 로고    scopus 로고
    • Survivin and molecular pathogenesis of colorectal cancer
    • Kim PJ, Plescia J, Clevers H, et al. Survivin and molecular pathogenesis of colorectal cancer. Lancet 2003;362:205-9.
    • (2003) Lancet , vol.362 , pp. 205-209
    • Kim, P.J.1    Plescia, J.2    Clevers, H.3
  • 30
    • 34548084157 scopus 로고    scopus 로고
    • The survivin isoform survivin-3B is cytoprotective and can function as a chromosomal passenger complex protein
    • Knauer SK, Bier C, Schlag P, et al. The survivin isoform survivin-3B is cytoprotective and can function as a chromosomal passenger complex protein. Cell Cycle 2007;6:1502-9.
    • (2007) Cell Cycle , vol.6 , pp. 1502-1509
    • Knauer, S.K.1    Bier, C.2    Schlag, P.3
  • 31
    • 33845971510 scopus 로고    scopus 로고
    • Nuclear export is essential for the tumor-promoting activity of survivin
    • Knauer SK, Kramer OH, Knosel T, et al. Nuclear export is essential for the tumor-promoting activity of survivin. Faseb J 2007;21:207-16.
    • (2007) Faseb J , vol.21 , pp. 207-216
    • Knauer, S.K.1    Kramer, O.H.2    Knosel, T.3
  • 32
    • 33947311353 scopus 로고    scopus 로고
    • Survivin's dual role: An export's view
    • Knauer SK, Mann W, Stauber RH. Survivin's dual role: an export's view. Cell Cycle 2007;6:518-21.
    • (2007) Cell Cycle , vol.6 , pp. 518-521
    • Knauer, S.K.1    Mann, W.2    Stauber, R.H.3
  • 33
    • 4444361250 scopus 로고    scopus 로고
    • Survivin expression is an independent prognostic factor in rectal cancer patients with and without preoperative radiotherapy
    • Knutsen A, Adell G , Sun XF. Survivin expression is an independent prognostic factor in rectal cancer patients with and without preoperative radiotherapy. Int J Radiat Oncol Biol Phys 2004;60:149-55.
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 149-155
    • Knutsen, A.1    Adell, G.2    Sun, X.F.3
  • 34
    • 0033573905 scopus 로고    scopus 로고
    • Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation
    • Kobayashi K, Hatano M, Otaki M, et al. Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc Natl Acad Sci U S A 1999;96:1457-62.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 1457-1462
    • Kobayashi, K.1    Hatano, M.2    Otaki, M.3
  • 35
    • 0032410818 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) and their emerging role in cancer
    • LaCasse EC, Baird S, Korneluk RG, et al. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 1998;17:3247-59.
    • (1998) Oncogene , vol.17 , pp. 3247-3259
    • LaCasse, E.C.1    Baird, S.2    Korneluk, R.G.3
  • 37
    • 0033258543 scopus 로고    scopus 로고
    • Pleiotropic cell-division defects and apoptosis induced by interference with survivin function
    • Li F, Ackermann EJ, Bennett CF, et al. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol 1999;1:461-66.
    • (1999) Nat Cell Biol , vol.1 , pp. 461-466
    • Li, F.1    Ackermann, E.J.2    Bennett, C.F.3
  • 38
    • 0033436285 scopus 로고    scopus 로고
    • Transcriptional analysis of human survivin gene expression
    • Li F , Altieri DC. Transcriptional analysis of human survivin gene expression. Biochem J 1999;344:305-11.
    • (1999) Biochem J , vol.344 , pp. 305-311
    • Li, F.1    Altieri, D.C.2
  • 39
    • 0033168929 scopus 로고    scopus 로고
    • The cancer antiapoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell cycledependent expression
    • Li F , Altieri DC. The cancer antiapoptosis mouse survivin gene: characterization of locus and transcriptional requirements of basal and cell cycledependent expression. Cancer Res 1999;59:3143-51.
    • (1999) Cancer Res , vol.59 , pp. 3143-3151
    • Li, F.1    Altieri, D.C.2
  • 40
    • 4844227693 scopus 로고    scopus 로고
    • Survivin as a therapeutic target for radiation sensitization in lung cancer
    • Lu B, Mu Y, Cao C, et al. Survivin as a therapeutic target for radiation sensitization in lung cancer. Cancer Res 2004;64:2840-45.
    • (2004) Cancer Res , vol.64 , pp. 2840-2845
    • Lu, B.1    Mu, Y.2    Cao, C.3
  • 41
    • 0033571983 scopus 로고    scopus 로고
    • Survivin-deltaEx3 and survivin-2B: Two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties
    • Mahotka C, Wenzel M, Springer E, et al. Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties. Cancer Res 1999;59:6097-102.
    • (1999) Cancer Res , vol.59 , pp. 6097-6102
    • Mahotka, C.1    Wenzel, M.2    Springer, E.3
  • 42
    • 0038182537 scopus 로고    scopus 로고
    • HBXIP functions as a cofactor of survivin in apoptosis suppression
    • Marusawa H, Matsuzawa S, Welsh K, et al. HBXIP functions as a cofactor of survivin in apoptosis suppression. Embo J 2003;22:2729-40.
    • (2003) Embo J , vol.22 , pp. 2729-2740
    • Marusawa, H.1    Matsuzawa, S.2    Welsh, K.3
  • 43
    • 0035024053 scopus 로고    scopus 로고
    • Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting
    • Mesri M, Morales-Ruiz M, Ackermann EJ, et al. Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting. Am J Pathol 2001;158:1757-65.
    • (2001) Am J Pathol , vol.158 , pp. 1757-1765
    • Mesri, M.1    Morales-Ruiz, M.2    Ackermann, E.J.3
  • 44
    • 33750482558 scopus 로고    scopus 로고
    • Acceleration of normal-tissue damage expression by early stimulation of cell proliferation in rat spinal cord
    • Nieder C, Andratschke N, Price RE, et al. Acceleration of normal-tissue damage expression by early stimulation of cell proliferation in rat spinal cord. Strahlenther Onkol 2006;182:680-84.
    • (2006) Strahlenther Onkol , vol.182 , pp. 680-684
    • Nieder, C.1    Andratschke, N.2    Price, R.E.3
  • 45
    • 0034700154 scopus 로고    scopus 로고
    • Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin
    • O'Connor DS, Grossman D, Plescia J, et al. Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin. Proc Natl Acad Sci USA 2000;97:13103-07.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13103-13107
    • O'Connor, D.S.1    Grossman, D.2    Plescia, J.3
  • 46
    • 0037379377 scopus 로고    scopus 로고
    • Radiosensitization of human melanoma cells by ribozyme-mediated inhibition of survivin expression
    • Pennati M, Binda M, Colella G, et al. Radiosensitization of human melanoma cells by ribozyme-mediated inhibition of survivin expression. J Invest Dermatol 2003;120:648-54.
    • (2003) J Invest Dermatol , vol.120 , pp. 648-654
    • Pennati, M.1    Binda, M.2    Colella, G.3
  • 47
    • 34447315861 scopus 로고    scopus 로고
    • Targeting survivin in cancer therapy: Fulfilled promises and open questions
    • Pennati M, Folini M, Zaffaroni N. Targeting survivin in cancer therapy: fulfilled promises and open questions. Carcinogenesis 2007;28:1133-39.
    • (2007) Carcinogenesis , vol.28 , pp. 1133-1139
    • Pennati, M.1    Folini, M.2    Zaffaroni, N.3
  • 48
    • 0037376549 scopus 로고    scopus 로고
    • Spontaneous and radiation-induced apoptosis in colorectal carcinoma cells with different intrinsic radiosensitivities: Survivin as a radioresistance factor
    • Rödel C, Haas J, Groth A, et al. Spontaneous and radiation-induced apoptosis in colorectal carcinoma cells with different intrinsic radiosensitivities: survivin as a radioresistance factor. Int J Radiat Oncol Biol Phys 2003;55:1341-7.
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 1341-1347
    • Rödel, C.1    Haas, J.2    Groth, A.3
  • 49
    • 0036338868 scopus 로고    scopus 로고
    • High survivin expression is associated with reduced apoptosis in rectal cancer and may predict disease-free survival after preoperative radiochemotherapy and surgical resection
    • Rödel F, Hoffmann J, Grabenbauer GG, et al. High survivin expression is associated with reduced apoptosis in rectal cancer and may predict disease-free survival after preoperative radiochemotherapy and surgical resection. Strahlenther Onkol 2002;178:426-35.
    • (2002) Strahlenther Onkol , vol.178 , pp. 426-435
    • Rödel, F.1    Hoffmann, J.2    Grabenbauer, G.G.3
  • 50
    • 19644370614 scopus 로고    scopus 로고
    • Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer
    • Rödel F, Hoffmann J, Distel L, et al. Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer. Cancer Res 2005;65:4881-7.
    • (2005) Cancer Res , vol.65 , pp. 4881-4887
    • Rödel, F.1    Hoffmann, J.2    Distel, L.3
  • 51
    • 36249030342 scopus 로고    scopus 로고
    • Der Apotoseinhibitor Survivin beeinflusst als Radioresistenzfaktor auch den Zellzyklus und DNA-Reparatur-Mechanismen
    • Sondernr 1:77
    • Rödel F, Müller B, Sieber R, et al. Der Apotoseinhibitor Survivin beeinflusst als Radioresistenzfaktor auch den Zellzyklus und DNA-Reparatur-Mechanismen. Strahlenther Onkol 2005;181 (Sondernr 1):77.
    • (2005) Strahlenther Onkol , pp. 181
    • Rödel, F.1    Müller, B.2    Sieber, R.3
  • 52
    • 36249029041 scopus 로고    scopus 로고
    • Steigerung der Apoptoserate und Strahlensensibilisierung kolorektaler Karzinomzellen durch eine Antisense-Oligonukleotid (Lilly LY2181308) vermittele Inhibition von Survivin
    • Sondernr 1:90
    • Rödel F, Müller B, Sieber R, et al. Steigerung der Apoptoserate und Strahlensensibilisierung kolorektaler Karzinomzellen durch eine Antisense-Oligonukleotid (Lilly LY2181308) vermittele Inhibition von Survivin. Strahlenther Onkol 2006;182 (Sondernr 1):90.
    • (2006) Strahlenther Onkol , pp. 182
    • Rödel, F.1    Müller, B.2    Sieber, R.3
  • 53
    • 36249000441 scopus 로고    scopus 로고
    • Rödel F, Knauer S, Mann W, et al. Ein nukleärer Export ist essentiell für die antiapoptotische Wirksamkeit von Survivin. Strahlenther Onkol 2007;183(Sondernr 1):60.
    • Rödel F, Knauer S, Mann W, et al. Ein nukleärer Export ist essentiell für die antiapoptotische Wirksamkeit von Survivin. Strahlenther Onkol 2007;183(Sondernr 1):60.
  • 54
    • 5644259587 scopus 로고    scopus 로고
    • Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice
    • Schimmer AD. Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice. Cancer Res 2004;64:7183-90.
    • (2004) Cancer Res , vol.64 , pp. 7183-7190
    • Schimmer, A.D.1
  • 55
    • 33749628166 scopus 로고    scopus 로고
    • Multiple dysregulated pathways in nasopharyngeal carcinoma revealed by gene expression profiling
    • Shi W, Bastianutto C, Li A, et al. Multiple dysregulated pathways in nasopharyngeal carcinoma revealed by gene expression profiling. Int J Cancer 2006;119:2467-75.
    • (2006) Int J Cancer , vol.119 , pp. 2467-2475
    • Shi, W.1    Bastianutto, C.2    Li, A.3
  • 56
    • 0035969963 scopus 로고    scopus 로고
    • An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7
    • Shin S, Sung BJ, Cho YS, et al. An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7. Biochemistry 2001;40:1117-23.
    • (2001) Biochemistry , vol.40 , pp. 1117-1123
    • Shin, S.1    Sung, B.J.2    Cho, Y.S.3
  • 57
    • 0037663452 scopus 로고    scopus 로고
    • Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis
    • Song Z, Yao X , Wu M. Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis. J Biol Chem 2003;278:23130-40.
    • (2003) J Biol Chem , vol.278 , pp. 23130-23140
    • Song, Z.1    Yao, X.2    Wu, M.3
  • 58
    • 34447120194 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic survivin: Molecular mechanism, prognostic, and therapeutic potential
    • Stauber RH, Mann W, Knauer SK. Nuclear and cytoplasmic survivin: molecular mechanism, prognostic, and therapeutic potential. Cancer Res 2007;67:5999-6002.
    • (2007) Cancer Res , vol.67 , pp. 5999-6002
    • Stauber, R.H.1    Mann, W.2    Knauer, S.K.3
  • 59
    • 33846921574 scopus 로고    scopus 로고
    • Correlation between survivin expression and locoregional control in cervical squamous cell carcinomas treated with radiation therapy
    • Suzuki Y, Oka K, Yoshida D, et al. Correlation between survivin expression and locoregional control in cervical squamous cell carcinomas treated with radiation therapy. Gynecol Oncol 2007;104:642-46.
    • (2007) Gynecol Oncol , vol.104 , pp. 642-646
    • Suzuki, Y.1    Oka, K.2    Yoshida, D.3
  • 60
    • 7744222944 scopus 로고    scopus 로고
    • Chromosomal passengers: The four-dimensional regulation of mitotic events
    • Vagnarelli P, Earnshaw WC. Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma 2004;113:211-22.
    • (2004) Chromosoma , vol.113 , pp. 211-222
    • Vagnarelli, P.1    Earnshaw, W.C.2
  • 61
    • 24744467419 scopus 로고    scopus 로고
    • Overexpression of survivin mRNA is associated with a favorable prognosis following neoadjuvant radiochemotherapy in esophageal cancer
    • Warnecke-Eberz U, Hokita S, Xi H, et al. Overexpression of survivin mRNA is associated with a favorable prognosis following neoadjuvant radiochemotherapy in esophageal cancer. Oncol Rep 2005;13:1241-6.
    • (2005) Oncol Rep , vol.13 , pp. 1241-1246
    • Warnecke-Eberz, U.1    Hokita, S.2    Xi, H.3
  • 62
    • 17844373531 scopus 로고    scopus 로고
    • Combined-modality treatment and organ preservation in bladder cancer. Do molecular markers predict outcome?
    • Weiss C, Rödel F, Wolf I, et al. Combined-modality treatment and organ preservation in bladder cancer. Do molecular markers predict outcome? Strahlenther Onkol 2005;181:213-22.
    • (2005) Strahlenther Onkol , vol.181 , pp. 213-222
    • Weiss, C.1    Rödel, F.2    Wolf, I.3
  • 63
    • 33645748832 scopus 로고    scopus 로고
    • Mitosis-independent survivin gene expression in vivo and regulation by p53
    • Xia F, Altieri DC. Mitosis-independent survivin gene expression in vivo and regulation by p53. Cancer Res 2006;66:3392-5.
    • (2006) Cancer Res , vol.66 , pp. 3392-3395
    • Xia, F.1    Altieri, D.C.2
  • 64
    • 4243182684 scopus 로고    scopus 로고
    • Tumor-specific gene expression using the survivin promoter is further increased by hypoxia
    • Yang L, Cao Z, Li F, et al. Tumor-specific gene expression using the survivin promoter is further increased by hypoxia. Gene Ther 2004;11:1215-23.
    • (2004) Gene Ther , vol.11 , pp. 1215-1223
    • Yang, L.1    Cao, Z.2    Li, F.3
  • 65
    • 33750338001 scopus 로고    scopus 로고
    • Prognostic significance of the Epstein-Barr virus, p53, Bcl-2, and survivin in nasopharyngeal cancer
    • Yip KW, Shi W, Pintilie M, et al. Prognostic significance of the Epstein-Barr virus, p53, Bcl-2, and survivin in nasopharyngeal cancer. Clin Cancer Res 2006;12:5726-32.
    • (2006) Clin Cancer Res , vol.12 , pp. 5726-5732
    • Yip, K.W.1    Shi, W.2    Pintilie, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.