Cinobufacini induces the apoptosis of U937 cells and its mechanism

Tumor

Volumn 27, Issue 5, 2007, Pages 341-344

  Zhang, Li ^a   Li, Jun Ming ^a   Qian, Ying ^a   Wang, Yan ^a   Shen, Zhi Xiang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Apoptosis; Cinobufagin; Fas fas 1; Leukemia,experimental; Proto oncogene protein bcl 2; U937 cells

Indexed keywords

CINOBUFAGIN; DNA FRAGMENT; FAS 1 ANTIGEN; FAS ANTIGEN; MESSENGER RNA; PROTEIN BCL 2; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL ASSAY; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IMMUNOFLUORESCENCE; LEUKEMIA CELL; NICK END LABELING; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 66749170172     PISSN: 10007431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Chinese source.
2. MASUDA Y, KAWAZOE N, NAKAJO S, et al. Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells[J]. Leuk Res, 1995,19(8): 549-556.
3. WATABE M, MASUDA Y, NAKAJO S, et al. The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells[J]. J Biol Chem, 1996,271(24): 14067-14072.
4. HASHIMOTO S, JING Y, KAWAZOE N, et al. Bufalin reduces the level of topoisomerase II in human leukemia cells and affects the cytotoxicity of anticancer drugs[J]. Leuk Res, 1997, 21 (9): 875-883.
5. Chinese source.
6. Chinese source.
7. Chinese source.
8. Chinese source.
9. Chinese source.
10. Chinese source.
11. ZEYTUN A, HASSUNEH M, NAQARKATTI M, et al. Fas-fas ligand based interactions between tumor cells and tumor specific cytotoxic T lymphocytes: a lethal two way street[J]. Blood, 1997, 90 (5): 1952-1959.