Glutamate-mediated down-regulation of the multidrug-resistance protein BCRP/ABCG2 in porcine and human brain capillaries

Molecular Pharmaceutics

Volumn 12, Issue 6, 2015, Pages 2049-2060

  Salvamoser, Josephine D ^a   Avemary, Janine ^a   Luna Munguia, Hiram ^a   Pascher, Bettina ^b   Getzinger, Thekla ^b   Pieper, Tom ^b   Kudernatsch, Manfred ^c   Kluger, Gerhard ^b,d   Potschka, Heidrun ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Epilepsy Center for Children and Adolescents   (Germany)

^c Schon Klinik Vogtareuth   (Germany)

^d PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

ABCG2; blood brain barrier; breast cancer resistance protein; drug resistance; glutamate; multidrug transporter; NMDA receptor

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; ARACHIDONIC ACID; BREAST CANCER RESISTANCE PROTEIN; CELECOXIB; CYCLOOXYGENASE 2; DIZOCILPINE; GLUTAMIC ACID; INDOMETACIN; MULTIDRUG RESISTANCE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; VERLUKAST; ABC TRANSPORTER; GLUCOSE TRANSPORTER 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CAPILLARY; BRAIN ISCHEMIA; CHILD; CONTROLLED STUDY; DOWN REGULATION; EPILEPSY; FEMALE; HUMAN; HUMAN TISSUE; MALE; NONHUMAN; PIG; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; ANIMAL; BRAIN; CAPILLARY; IN VITRO STUDY; METABOLISM;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BRAIN; CAPILLARIES; FEMALE; GLUCOSE TRANSPORTER TYPE 1; GLUTAMIC ACID; HUMANS; IN VITRO TECHNIQUES; MALE; SWINE;

EID: 84930662570     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500841w     Document Type: Article

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