-
1
-
-
70449529433
-
Structure and function of the blood-brain barrier
-
Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ. Structure and function of the blood-brain barrier. Neurobiol Dis 2010; 37: 13-25.
-
(2010)
Neurobiol Dis
, vol.37
, pp. 13-25
-
-
Abbott, N.J.1
Patabendige, A.A.2
Dolman, D.E.3
Yusof, S.R.4
Begley, D.J.5
-
2
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic BV. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 2008; 57: 178-201.
-
(2008)
Neuron
, vol.57
, pp. 178-201
-
-
Zlokovic, B.V.1
-
3
-
-
80055014830
-
Central nervous system pericytes in health and disease
-
Winkler EA, Bell RD, Zlokovic BV. Central nervous system pericytes in health and disease. Nat Neurosci 2011; 14: 1398-405.
-
(2011)
Nat Neurosci
, vol.14
, pp. 1398-1405
-
-
Winkler, E.A.1
Bell, R.D.2
Zlokovic, B.V.3
-
4
-
-
78649487239
-
Pericytes are required for blood-brain barrier integrity during embryogenesis
-
Daneman R, Zhou L, Kebede AA, Barres BA. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 2010; 468: 562-6.
-
(2010)
Nature
, vol.468
, pp. 562-566
-
-
Daneman, R.1
Zhou, L.2
Kebede, A.A.3
Barres, B.A.4
-
5
-
-
79961175318
-
The neurovascular link in health and disease: Molecular mechanisms and therapeutic implications
-
Quaegebeur A, Lange C, Carmeliet P. The neurovascular link in health and disease: molecular mechanisms and therapeutic implications. Neuron 2011; 71: 406-24.
-
(2011)
Neuron
, vol.71
, pp. 406-424
-
-
Quaegebeur, A.1
Lange, C.2
Carmeliet, P.3
-
6
-
-
78651376221
-
Evolution of ABC transporters by gene duplication and their role in human disease
-
Moitra K, Dean M. Evolution of ABC transporters by gene duplication and their role in human disease. Biol Chem 2011; 392: 29-37.
-
(2011)
Biol Chem
, vol.392
, pp. 29-37
-
-
Moitra, K.1
Dean, M.2
-
7
-
-
77954920933
-
Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 downregulates blood-brain barrier breast cancer resistance protein
-
Hartz AM, Madole EK, Miller DS, Bauer B. Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 downregulates blood-brain barrier breast cancer resistance protein. J Pharmacol Exp Ther 2010; 334: 467-76.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 467-476
-
-
Hartz, A.M.1
Madole, E.K.2
Miller, D.S.3
Bauer, B.4
-
8
-
-
0030001001
-
Clinical trials of P-glycoprotein reversal in solid tumours
-
Ferry DR, Traunecker H, Kerr DJ. Clinical trials of P-glycoprotein reversal in solid tumours. Eur J Cancer 1996; 32A: 1070-81.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 1070-1081
-
-
Ferry, D.R.1
Traunecker, H.2
Kerr, D.J.3
-
9
-
-
33747202180
-
Multidrug transporters as drug targets
-
Liang XJ, Aszalos A. Multidrug transporters as drug targets. Curr Drug Targets 2006; 7: 911-21.
-
(2006)
Curr Drug Targets
, vol.7
, pp. 911-921
-
-
Liang, X.J.1
Aszalos, A.2
-
10
-
-
0345504156
-
Increased intracellular drug accumulation and complete chemosensitization achieved in multidrug-resistant solid tumors by co-administering valspodar (PSC 833) with sterically stabilized liposomal doxorubicin
-
Krishna R, St-Louis M, Mayer LD. Increased intracellular drug accumulation and complete chemosensitization achieved in multidrug-resistant solid tumors by co-administering valspodar (PSC 833) with sterically stabilized liposomal doxorubicin. Int J Cancer 2000; 85: 131-41.
-
(2000)
Int J Cancer
, vol.85
, pp. 131-141
-
-
Krishna, R.1
St-Louis, M.2
Mayer, L.D.3
-
11
-
-
81555200043
-
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
-
Zlokovic BV. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 2011; 12: 723-38.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 723-738
-
-
Zlokovic, B.V.1
-
12
-
-
80053538365
-
Breast cancer resistance protein and P-glycoprotein in brain cancer: Two gatekeepers team up
-
Agarwal S, Hartz AM, Elmquist WF, Bauer B. Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up. Curr Pharm Des 2011; 17: 2793-802.
-
(2011)
Curr Pharm Des
, vol.17
, pp. 2793-2802
-
-
Agarwal, S.1
Hartz, A.M.2
Elmquist, W.F.3
Bauer, B.4
-
13
-
-
59649115878
-
An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethy l]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016)
-
Polli JW, Olson KL, Chism JP, et al. An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethy l]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016). Drug Metab Dispos 2009; 37: 439-42.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 439-442
-
-
Polli, J.W.1
Olson, K.L.2
Chism, J.P.3
-
14
-
-
84862084237
-
Quantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout mice
-
Agarwal S, Uchida Y, Mittapalli RK, Sane R, Terasaki T, Elmquist WF. Quantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout mice. Drug Metab Dispos 2012; 40: 1164-9.
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 1164-1169
-
-
Agarwal, S.1
Uchida, Y.2
Mittapalli, R.K.3
Sane, R.4
Terasaki, T.5
Elmquist, W.F.6
-
15
-
-
79961096875
-
Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels
-
Shawahna R, Uchida Y, Decleves X, et al. Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels. Mol Pharm 2011; 8: 1332-41.
-
(2011)
Mol Pharm
, vol.8
, pp. 1332-1341
-
-
Shawahna, R.1
Uchida, Y.2
Decleves, X.3
-
16
-
-
4944230477
-
Pregnane X receptor upregulation of P-glycoprotein expression and transport function at the blood-brain barrier
-
Bauer B, Hartz AM, Fricker G, Miller DS. Pregnane X receptor upregulation of P-glycoprotein expression and transport function at the blood-brain barrier. Mol Pharmacol 2004; 66: 413-9.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 413-419
-
-
Bauer, B.1
Hartz, A.M.2
Fricker, G.3
Miller, D.S.4
-
17
-
-
33748950454
-
In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation
-
Bauer B, Yang X, Hartz AM, et al. In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation. Mol Pharmacol 2006; 70: 1212-9.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1212-1219
-
-
Bauer, B.1
Yang, X.2
Hartz, A.M.3
-
18
-
-
77956237647
-
Constitutive androstane receptormediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier
-
Wang X, Sykes DB, Miller DS. Constitutive androstane receptormediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. Mol Pharmacol 2010; 78: 376-83.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 376-383
-
-
Wang, X.1
Sykes, D.B.2
Miller, D.S.3
-
19
-
-
79551639774
-
Aryl hydrocarbon receptormediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier
-
Wang X, Hawkins BT, Miller DS. Aryl hydrocarbon receptormediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. FASEB J 2011; 25: 644-52.
-
(2011)
FASEB J
, vol.25
, pp. 644-652
-
-
Wang, X.1
Hawkins, B.T.2
Miller, D.S.3
-
20
-
-
79956223783
-
1Alpha, 25-dihydroxyvitamin D3 up-regulates P-glycoprotein via the vitamin D receptor and not farnesoid X receptor in both fxr(-/-) and fxr(+/+) mice and increased renal and brain efflux of digoxin in mice in vivo
-
Chow EC, Durk MR, Cummins CL, Pang KS. 1Alpha, 25-dihydroxyvitamin D3 up-regulates P-glycoprotein via the vitamin D receptor and not farnesoid X receptor in both fxr(-/-) and fxr(+/+) mice and increased renal and brain efflux of digoxin in mice in vivo. J Pharmacol Exp Ther 2011; 337: 846-59.
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 846-859
-
-
Chow, E.C.1
Durk, M.R.2
Cummins, C.L.3
Pang, K.S.4
-
21
-
-
55949099344
-
Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier
-
Narang VS, Fraga C, Kumar N, et al. Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier. Am J Physiol Cell Physiol 2008; 295: C440-50.
-
(2008)
Am J Physiol Cell Physiol
, vol.295
-
-
Narang, V.S.1
Fraga, C.2
Kumar, N.3
-
22
-
-
0036605677
-
Functional expression and localization of P-glycoprotein at the blood brain barrier
-
Bendayan R, Lee G, Bendayan M. Functional expression and localization of P-glycoprotein at the blood brain barrier. Microsc Res Tech 2002; 57: 365-80.
-
(2002)
Microsc Res Tech
, vol.57
, pp. 365-380
-
-
Bendayan, R.1
Lee, G.2
Bendayan, M.3
-
23
-
-
77956268005
-
Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay
-
Hawkins BT, Rigor RR, Miller DS. Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay. J Cereb Blood Flow Metab 2010; 30: 1593-7.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1593-1597
-
-
Hawkins, B.T.1
Rigor, R.R.2
Miller, D.S.3
-
24
-
-
0035831541
-
Transporters on demand: Intrahepatic pools of canalicular ATP binding cassette transporters in rat liver
-
Kipp H, Pichetshote N, Arias IM. Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver. J Biol Chem 2001; 276: 7218-24.
-
(2001)
J Biol Chem
, vol.276
, pp. 7218-7224
-
-
Kipp, H.1
Pichetshote, N.2
Arias, I.M.3
-
25
-
-
33947279373
-
Modulation of pglycoprotein function by caveolin-1 phosphorylation
-
Barakat S, Demeule M, Pilorget A, et al. Modulation of pglycoprotein function by caveolin-1 phosphorylation. J Neurochem 2007; 101: 1-8.
-
(2007)
J Neurochem
, vol.101
, pp. 1-8
-
-
Barakat, S.1
Demeule, M.2
Pilorget, A.3
-
26
-
-
44749088919
-
Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction
-
Barakat S, Turcotte S, Demeule M, et al. Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction. Biochem Biophys Res Commun 2008; 372: 440-6.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 440-446
-
-
Barakat, S.1
Turcotte, S.2
Demeule, M.3
-
27
-
-
84897398839
-
Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells
-
Zhong Y, Hennig B, Toborek M. Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells. J Cereb Blood Flow Metab 2009.
-
(2009)
J Cereb Blood Flow Metab
-
-
Zhong, Y.1
Hennig, B.2
Toborek, M.3
-
28
-
-
34548843672
-
Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro
-
Storch CH, Ehehalt R, Haefeli WE, Weiss J. Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. J Pharmacol Exp Ther 2007; 323: 257-64.
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 257-264
-
-
Storch, C.H.1
Ehehalt, R.2
Haefeli, W.E.3
Weiss, J.4
-
29
-
-
84865346007
-
Pglycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia
-
McCaffrey G, Staatz WD, Sanchez-Covarrubias L, et al. Pglycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia. J Neurochem 2012; 122: 962-75.
-
(2012)
J Neurochem
, vol.122
, pp. 962-975
-
-
McCaffrey, G.1
Staatz, W.D.2
Sanchez-Covarrubias, L.3
-
30
-
-
79952001112
-
Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier
-
Ronaldson PT, Finch JD, Demarco KM, Quigley CE, Davis TP. Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier. J Pharmacol Exp Ther 2011; 336: 827-39.
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 827-839
-
-
Ronaldson, P.T.1
Finch, J.D.2
Demarco, K.M.3
Quigley, C.E.4
Davis, T.P.5
-
31
-
-
84856414098
-
Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain
-
Lochhead JJ, McCaffrey G, Sanchez-Covarrubias L, et al. Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain. Am J Physiol Heart Circ Physiol 2012; 302: H582-93.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
Lochhead, J.J.1
McCaffrey, G.2
Sanchez-Covarrubias, L.3
-
32
-
-
77954920933
-
Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 downregulates blood-brain barrier breast cancer resistance protein
-
Hartz AM, Madole EK, Miller DS, Bauer B. Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 downregulates blood-brain barrier breast cancer resistance protein. J Pharmacol Exp Ther 2010; 334: 467-76.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 467-476
-
-
Hartz, A.M.1
Madole, E.K.2
Miller, D.S.3
Bauer, B.4
-
34
-
-
77957727364
-
BCRP at the Blood-Brain Barrier: Genomic Regulation by 17beta-Estradiol
-
Mahringer A, Fricker G. BCRP at the Blood-Brain Barrier: Genomic Regulation by 17beta-Estradiol. Mol Pharm 2010.
-
(2010)
Mol Pharm
-
-
Mahringer, A.1
Fricker, G.2
-
35
-
-
30744477950
-
From angiogenesis to neuropathology
-
Greenberg DA, Jin K. From angiogenesis to neuropathology. Nature 2005; 438: 954-9.
-
(2005)
Nature
, vol.438
, pp. 954-959
-
-
Greenberg, D.A.1
Jin, K.2
-
36
-
-
75349108100
-
Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor
-
Hawkins BT, Sykes DB, Miller DS. Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor. J Neurosci 2010; 30: 1417-25.
-
(2010)
J Neurosci
, vol.30
, pp. 1417-1425
-
-
Hawkins, B.T.1
Sykes, D.B.2
Miller, D.S.3
-
37
-
-
77956268005
-
Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay
-
Hawkins BT, Rigor RR, Miller DS. Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay. J Cereb Blood Flow Metab 2010; 30: 1593-7.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1593-1597
-
-
Hawkins, B.T.1
Rigor, R.R.2
Miller, D.S.3
-
38
-
-
0036019498
-
Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants--a case of molecular hijacking
-
Miller DS. Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants--a case of molecular hijacking. J Biochem Mol Toxicol 2002; 16: 121-7.
-
(2002)
J Biochem Mol Toxicol
, vol.16
, pp. 121-127
-
-
Miller, D.S.1
-
39
-
-
4944230261
-
Rapid regulation of Pglycoprotein at the blood-brain barrier by endothelin-1
-
Hartz AM, Bauer B, Fricker G, Miller DS. Rapid regulation of Pglycoprotein at the blood-brain barrier by endothelin-1. Mol Pharmacol 2004; 66: 387-94.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 387-394
-
-
Hartz, A.M.1
Bauer, B.2
Fricker, G.3
Miller, D.S.4
-
40
-
-
31044447881
-
Rapid modulation of Pglycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide
-
Hartz AM, Bauer B, Fricker G, Miller DS. Rapid modulation of Pglycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide. Mol Pharmacol 2006; 69: 462-70.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 462-470
-
-
Hartz, A.M.1
Bauer, B.2
Fricker, G.3
Miller, D.S.4
-
41
-
-
84866844026
-
Targeting Blood-Brain Barrier Sphingolipid Signaling Reduces Basal PGlycoprotein Activity and Improves Drug Delivery to the Brain
-
Cannon RE PJ, Hawkins BT, Campos CR, Miller DS. Targeting Blood-Brain Barrier Sphingolipid Signaling Reduces Basal PGlycoprotein Activity and Improves Drug Delivery to the Brain. Pric Nat Acad Sci 2012.
-
(2012)
Pric Nat Acad Sci
-
-
Cannon, R.E.P.J.1
Hawkins, B.T.2
Campos, C.R.3
Miller, D.S.4
-
42
-
-
33847094700
-
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier
-
Bauer B, Hartz AM, Miller DS. Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Mol Pharmacol 2007; 71: 667-75.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 667-675
-
-
Bauer, B.1
Hartz, A.M.2
Miller, D.S.3
-
43
-
-
77954242152
-
Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain
-
Rigor RR, Hawkins BT, Miller DS. Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain. J Cereb Blood Flow Metab 2010; 30: 1373-83.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1373-1383
-
-
Rigor, R.R.1
Hawkins, B.T.2
Miller, D.S.3
-
44
-
-
78049502852
-
Extracellular and intracellular actions of sphingosine-1-phosphate
-
Strub GM, Maceyka M, Hait NC, Milstien S, Spiegel S. Extracellular and intracellular actions of sphingosine-1-phosphate. Adv Exp Med Biol 2010; 688: 141-55.
-
(2010)
Adv Exp Med Biol
, vol.688
, pp. 141-155
-
-
Strub, G.M.1
Maceyka, M.2
Hait, N.C.3
Milstien, S.4
Spiegel, S.5
-
45
-
-
79551674537
-
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
-
Choi JW, Gardell SE, Herr DR, et al. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation. Proc Natl Acad Sci U S A 2011; 108: 751-6.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 751-756
-
-
Choi, J.W.1
Gardell, S.E.2
Herr, D.R.3
-
46
-
-
79955455801
-
Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis
-
Cohen JA, Chun J. Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. Ann Neurol 2011; 69: 759-77.
-
(2011)
Ann Neurol
, vol.69
, pp. 759-777
-
-
Cohen, J.A.1
Chun, J.2
-
47
-
-
42449149172
-
Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling
-
Bauer B, Hartz AM, Pekcec A, Toellner K, Miller DS, Potschka H. Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling. Mol Pharmacol 2008; 73: 1444-53.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1444-1453
-
-
Bauer, B.1
Hartz, A.M.2
Pekcec, A.3
Toellner, K.4
Miller, D.S.5
Potschka, H.6
-
48
-
-
70349336797
-
Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases
-
Edwards LJ, Constantinescu CS. Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases. Inflamm Allergy Drug Targets 2009; 8: 182-90.
-
(2009)
Inflamm Allergy Drug Targets
, vol.8
, pp. 182-190
-
-
Edwards, L.J.1
Constantinescu, C.S.2
-
49
-
-
0035425507
-
Multidrug-resistance Pglycoprotein (MDR1) secretes platelet-activating factor
-
Raggers RJ, Vogels I, van Meer G. Multidrug-resistance Pglycoprotein (MDR1) secretes platelet-activating factor. Biochem J 2001; 357: 859-65.
-
(2001)
Biochem J
, vol.357
, pp. 859-865
-
-
Raggers, R.J.1
Vogels, I.2
van Meer, G.3
-
50
-
-
0032709624
-
Secretion of platelet-activating factor is mediated by MDR1 P-glycoprotein in cultured human mesangial cells
-
Ernest S, Bello-Reuss E. Secretion of platelet-activating factor is mediated by MDR1 P-glycoprotein in cultured human mesangial cells. J Am Soc Nephrol 1999; 10: 2306-13.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 2306-2313
-
-
Ernest, S.1
Bello-Reuss, E.2
-
51
-
-
79953187904
-
Absence of PAF receptor alters cellular infiltrate but not rolling and adhesion of leukocytes in experimental autoimmune encephalomyelitis
-
Rodrigues DH, Lacerda-Queiroz N, de Miranda AS, et al. Absence of PAF receptor alters cellular infiltrate but not rolling and adhesion of leukocytes in experimental autoimmune encephalomyelitis. Brain Res 2011; 1385: 298-306.
-
(2011)
Brain Res
, vol.1385
, pp. 298-306
-
-
Rodrigues, D.H.1
Lacerda-Queiroz, N.2
de Miranda, A.S.3
-
52
-
-
0033081106
-
Platelet activating factor is elevated in cerebral spinal fluid and plasma of patients with relapsing-remitting multiple sclerosis
-
Callea L, Arese M, Orlandini A, Bargnani C, Priori A, Bussolino F. Platelet activating factor is elevated in cerebral spinal fluid and plasma of patients with relapsing-remitting multiple sclerosis. J Neuroimmunol 1999; 94: 212-21.
-
(1999)
J Neuroimmunol
, vol.94
, pp. 212-221
-
-
Callea, L.1
Arese, M.2
Orlandini, A.3
Bargnani, C.4
Priori, A.5
Bussolino, F.6
-
53
-
-
77954012943
-
P-glycoprotein acts as an immunomodulator during neuroinflammation
-
Kooij G, Backer R, Koning JJ, et al. P-glycoprotein acts as an immunomodulator during neuroinflammation. PLoS One 2009; 4: e8212.
-
(2009)
PLoS One
, vol.4
-
-
Kooij, G.1
Backer, R.2
Koning, J.J.3
-
54
-
-
77952240450
-
T lymphocytes impair P-glycoprotein function during neuroinflammation
-
Kooij G, van Horssen J, de Lange EC, et al. T lymphocytes impair P-glycoprotein function during neuroinflammation. J Autoimmun 2010; 34: 416-25.
-
(2010)
J Autoimmun
, vol.34
, pp. 416-425
-
-
Kooij, G.1
van Horssen, J.2
de Lange, E.C.3
-
55
-
-
79957947154
-
Activating PKC-beta1 at the blood-brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS
-
Wang X, Hawkins BT, Miller DS. Activating PKC-beta1 at the blood-brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS. J Cereb Blood Flow Metab 2011; 31: 1371-5.
-
(2011)
J Cereb Blood Flow Metab
, vol.31
, pp. 1371-1375
-
-
Wang, X.1
Hawkins, B.T.2
Miller, D.S.3
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