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Volumn 9, Issue , 2012, Pages

Susceptibility of juvenile and adult blood-brain barrier to endothelin-1: Regulation of P-glycoprotein and breast cancer resistance protein expression and transport activity

Author keywords

Brain to blood transport; Breast cancer resistance protein; Drug transport; Endothelin 1; Juvenile and adult blood brain barrier; Neuroinflammation; P glycoprotein

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; ENDOTHELIN 1; FRACTALKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

EID: 84871133567     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-273     Document Type: Article
Times cited : (32)

References (63)
  • 1
    • 23044500398 scopus 로고    scopus 로고
    • Drug resistance in brain diseases and the role of drug efflux transporters
    • Loscher W, Potschka H. Drug resistance in brain diseases and the role of drug efflux transporters. Nat Rev Neurosci 2005, 6:591-602.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 591-602
    • Loscher, W.1    Potschka, H.2
  • 2
    • 1642454475 scopus 로고    scopus 로고
    • ABC transporters and the blood-brain barrier
    • 10.2174/1381612043384844, 15134482
    • Begley DJ. ABC transporters and the blood-brain barrier. Curr Pharm Des 2004, 10:1295-1312. 10.2174/1381612043384844, 15134482.
    • (2004) Curr Pharm Des , vol.10 , pp. 1295-1312
    • Begley, D.J.1
  • 3
    • 22744440362 scopus 로고    scopus 로고
    • Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
    • 10.1016/j.pneurobio.2005.04.006, 16011870
    • Loscher W, Potschka H. Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases. Prog Neurobiol 2005, 76:22-76. 10.1016/j.pneurobio.2005.04.006, 16011870.
    • (2005) Prog Neurobiol , vol.76 , pp. 22-76
    • Loscher, W.1    Potschka, H.2
  • 5
    • 62949174356 scopus 로고    scopus 로고
    • Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation
    • 10.1128/AAC.00733-08, 2650525, 19075072
    • Bousquet L, Pruvost A, Guyot AC, Farinotti R, Mabondzo A. Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation. Antimicrob Agents Chemother 2009, 53:896-902. 10.1128/AAC.00733-08, 2650525, 19075072.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 896-902
    • Bousquet, L.1    Pruvost, A.2    Guyot, A.C.3    Farinotti, R.4    Mabondzo, A.5
  • 6
    • 80053900477 scopus 로고    scopus 로고
    • Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: multiplex quantification with path analysis
    • 10.1016/j.bbi.2011.06.006, 3389494, 21704698
    • Erickson MA, Banks WA. Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: multiplex quantification with path analysis. Brain Behav Immun 2011, 25:1637-1648. 10.1016/j.bbi.2011.06.006, 3389494, 21704698.
    • (2011) Brain Behav Immun , vol.25 , pp. 1637-1648
    • Erickson, M.A.1    Banks, W.A.2
  • 7
    • 55049099747 scopus 로고    scopus 로고
    • Endothelin-1 reduces p-glycoprotein transport activity in an in vitro model of human adult blood-brain barrier
    • 10.1007/s10571-008-9277-y, 18379872
    • Hembury A, Mabondzo A. Endothelin-1 reduces p-glycoprotein transport activity in an in vitro model of human adult blood-brain barrier. Cell Mol Neurobiol 2008, 28:915-921. 10.1007/s10571-008-9277-y, 18379872.
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 915-921
    • Hembury, A.1    Mabondzo, A.2
  • 8
    • 77953687856 scopus 로고    scopus 로고
    • Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier
    • 10.1016/j.tips.2010.03.003, 2882496, 20417575
    • Miller DS. Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier. Trends Pharmacol Sci 2010, 31:246-254. 10.1016/j.tips.2010.03.003, 2882496, 20417575.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 246-254
    • Miller, D.S.1
  • 9
    • 67649097117 scopus 로고    scopus 로고
    • Lipopolysaccharide impairs blood brain barrier P-glycoprotein function in mice through prostaglandin- and nitric oxide independent pathways
    • Salkeni MA, Lynch JL, Price TO, Banks WA. Lipopolysaccharide impairs blood brain barrier P-glycoprotein function in mice through prostaglandin- and nitric oxide independent pathways. J Neuroimmune Pharmacology 2009, 4:276-282.
    • (2009) J Neuroimmune Pharmacology , vol.4 , pp. 276-282
    • Salkeni, M.A.1    Lynch, J.L.2    Price, T.O.3    Banks, W.A.4
  • 10
    • 79956194621 scopus 로고    scopus 로고
    • Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study
    • 10.1186/1742-2094-8-55, 3121616, 21599903
    • Brochu ME, Girard S, Lavoie K, Sébire G. Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study. J Neuroinflammation 2011, 8:55. 10.1186/1742-2094-8-55, 3121616, 21599903.
    • (2011) J Neuroinflammation , vol.8 , pp. 55
    • Brochu, M.E.1    Girard, S.2    Lavoie, K.3    Sébire, G.4
  • 11
    • 33747604377 scopus 로고    scopus 로고
    • HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein
    • 10.1124/mol.106.025973, 16790532
    • Ronaldson PT, Bendayan R. HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein. Mol Pharmacol 2006, 70:1087-1098. 10.1124/mol.106.025973, 16790532.
    • (2006) Mol Pharmacol , vol.70 , pp. 1087-1098
    • Ronaldson, P.T.1    Bendayan, R.2
  • 12
    • 0142071056 scopus 로고    scopus 로고
    • Influence of tumor necrosis factor-alpha on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT
    • 10.1016/S0006-2952(03)00340-X, 12906922
    • Theron D, Barraud de Lagerie S, Tardivel S, Pelerin H, Demeuse P, Mercier C, Mabondzo A, Farinotti R, Lacour B, Roux F, Gimenez F. Influence of tumor necrosis factor-alpha on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT. Biochem Pharmacol 2003, 66:579-587. 10.1016/S0006-2952(03)00340-X, 12906922.
    • (2003) Biochem Pharmacol , vol.66 , pp. 579-587
    • Theron, D.1    Barraud de Lagerie, S.2    Tardivel, S.3    Pelerin, H.4    Demeuse, P.5    Mercier, C.6    Mabondzo, A.7    Farinotti, R.8    Lacour, B.9    Roux, F.10    Gimenez, F.11
  • 13
    • 0037716531 scopus 로고    scopus 로고
    • Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin
    • 10.1038/sj.bjp.0705227, 1573825, 12746221
    • Goralski KB, Hartmann G, Piquette-Miller M, Renton KW. Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin. Br J Pharmacol 2003, 139:35-48. 10.1038/sj.bjp.0705227, 1573825, 12746221.
    • (2003) Br J Pharmacol , vol.139 , pp. 35-48
    • Goralski, K.B.1    Hartmann, G.2    Piquette-Miller, M.3    Renton, K.W.4
  • 14
    • 0023805236 scopus 로고
    • Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats
    • 10.1016/0014-2999(88)90425-6, 2907490
    • Wright CE, Fozard JR. Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats. Eur J Pharmacol 1988, 155:201-203. 10.1016/0014-2999(88)90425-6, 2907490.
    • (1988) Eur J Pharmacol , vol.155 , pp. 201-203
    • Wright, C.E.1    Fozard, J.R.2
  • 15
    • 0029112769 scopus 로고
    • Therapeutic effects of endothelin receptor antagonists in stroke
    • Barone FC, Willette RN, Yue TL, Feurestein G. Therapeutic effects of endothelin receptor antagonists in stroke. Neurol Res 1995, 17:259-264.
    • (1995) Neurol Res , vol.17 , pp. 259-264
    • Barone, F.C.1    Willette, R.N.2    Yue, T.L.3    Feurestein, G.4
  • 16
    • 4744368925 scopus 로고    scopus 로고
    • Effects of HIV drug combinations on endothelin-1 and vascular cell proliferation
    • 10.1385/CT:4:2:117, 15371629
    • Hebert VY, Crenshaw BL, Romanoff RL, Ekshyyan VP, Dugas TR. Effects of HIV drug combinations on endothelin-1 and vascular cell proliferation. Cardiovasc Toxicol 2004, 4:117-131. 10.1385/CT:4:2:117, 15371629.
    • (2004) Cardiovasc Toxicol , vol.4 , pp. 117-131
    • Hebert, V.Y.1    Crenshaw, B.L.2    Romanoff, R.L.3    Ekshyyan, V.P.4    Dugas, T.R.5
  • 17
    • 33745893549 scopus 로고    scopus 로고
    • Antiretrovirals induce direct endothelial dysfunction in vivo
    • 10.1097/01.qai.0000228790.40235.0c, 16810107
    • Jiang B, Hebert VY, Zavecz JH, Dugas TR. Antiretrovirals induce direct endothelial dysfunction in vivo. J Acquir Immune Defic Syndr 2006, 42:391-395. 10.1097/01.qai.0000228790.40235.0c, 16810107.
    • (2006) J Acquir Immune Defic Syndr , vol.42 , pp. 391-395
    • Jiang, B.1    Hebert, V.Y.2    Zavecz, J.H.3    Dugas, T.R.4
  • 18
    • 0028284251 scopus 로고
    • Endothelin-1 in cerebrospinal fluid in elderly patients with hypertension and dementia
    • 10.1161/01.HYP.24.1.97, 8021015
    • Nakajima M, Morimoto S, Takamoto S, Kitano S, Fukuo K, Onishi T, Ogihara T. Endothelin-1 in cerebrospinal fluid in elderly patients with hypertension and dementia. Hypertension 1994, 24:97-100. 10.1161/01.HYP.24.1.97, 8021015.
    • (1994) Hypertension , vol.24 , pp. 97-100
    • Nakajima, M.1    Morimoto, S.2    Takamoto, S.3    Kitano, S.4    Fukuo, K.5    Onishi, T.6    Ogihara, T.7
  • 19
    • 0029858109 scopus 로고    scopus 로고
    • Endothelin peptides in brain diseases
    • Nie XJ, Olsson Y. Endothelin peptides in brain diseases. Rev Neurosci 1996, 7:177-186.
    • (1996) Rev Neurosci , vol.7 , pp. 177-186
    • Nie, X.J.1    Olsson, Y.2
  • 20
    • 0032881899 scopus 로고    scopus 로고
    • Endothelin-1 is elevated in the cerebrospinal fluid of HIV-infected patients with encephalopathy
    • 10.1007/s150100050020, 10885834
    • Rolinski B, Heigermoser A, Lederer E, Bogner JR, Loch O, Goebel FD. Endothelin-1 is elevated in the cerebrospinal fluid of HIV-infected patients with encephalopathy. Infection 1999, 27:244-247. 10.1007/s150100050020, 10885834.
    • (1999) Infection , vol.27 , pp. 244-247
    • Rolinski, B.1    Heigermoser, A.2    Lederer, E.3    Bogner, J.R.4    Loch, O.5    Goebel, F.D.6
  • 22
    • 33645960685 scopus 로고    scopus 로고
    • Pharmacology and physiopathology of the brain endothelin system: an overview
    • 10.2174/092986706776055652, 16529555
    • Schinelli S. Pharmacology and physiopathology of the brain endothelin system: an overview. Curr Med Chem 2006, 13:627-638. 10.2174/092986706776055652, 16529555.
    • (2006) Curr Med Chem , vol.13 , pp. 627-638
    • Schinelli, S.1
  • 24
    • 0026755699 scopus 로고
    • The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage
    • 10.3171/jns.1992.77.1.0096, 1607979
    • Suzuki R, Masaoka H, Hirata Y, Marumo F, Isotani E, Hirakawa K. The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg 1992, 77:96-100. 10.3171/jns.1992.77.1.0096, 1607979.
    • (1992) J Neurosurg , vol.77 , pp. 96-100
    • Suzuki, R.1    Masaoka, H.2    Hirata, Y.3    Marumo, F.4    Isotani, E.5    Hirakawa, K.6
  • 25
    • 0026708624 scopus 로고
    • Increased plasma endothelin-1 in acute ischemic stroke
    • 10.1161/01.STR.23.7.1014, 1615534
    • Ziv I, Fleminger G, Djaldetti R, Achiron A, Melamed E, Sokolovsky M. Increased plasma endothelin-1 in acute ischemic stroke. Stroke 1992, 23:1014-1016. 10.1161/01.STR.23.7.1014, 1615534.
    • (1992) Stroke , vol.23 , pp. 1014-1016
    • Ziv, I.1    Fleminger, G.2    Djaldetti, R.3    Achiron, A.4    Melamed, E.5    Sokolovsky, M.6
  • 26
    • 33847408485 scopus 로고    scopus 로고
    • Molecular programming of endothelin-1 in HIV-infected brain: role of Tat in up-regulation of ET-1 and its inhibition by statins
    • 10.1096/fj.06-7054com, 17197385
    • Chauhan A, Hahn S, Gartner S, Pardo CA, Netesan SK, McArthur J, Nath A. Molecular programming of endothelin-1 in HIV-infected brain: role of Tat in up-regulation of ET-1 and its inhibition by statins. FASEB J 2007, 21:777-789. 10.1096/fj.06-7054com, 17197385.
    • (2007) FASEB J , vol.21 , pp. 777-789
    • Chauhan, A.1    Hahn, S.2    Gartner, S.3    Pardo, C.A.4    Netesan, S.K.5    McArthur, J.6    Nath, A.7
  • 27
    • 0037007826 scopus 로고    scopus 로고
    • HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier
    • 10.1097/00001756-200207020-00022, 12151765
    • Didier N, Banks WA, Creminon C, Reuddre-Bosquet N, Mabondzo A. HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier. Neuroreport 2002, 13:1179-1183. 10.1097/00001756-200207020-00022, 12151765.
    • (2002) Neuroreport , vol.13 , pp. 1179-1183
    • Didier, N.1    Banks, W.A.2    Creminon, C.3    Reuddre-Bosquet, N.4    Mabondzo, A.5
  • 28
    • 0037971138 scopus 로고    scopus 로고
    • Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability
    • Didier N, Romero IA, Creminon C, Wijkhuisen A, Grassi J, Mabondzo A. Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability. J Neurochem 2003, 86:246-254.
    • (2003) J Neurochem , vol.86 , pp. 246-254
    • Didier, N.1    Romero, I.A.2    Creminon, C.3    Wijkhuisen, A.4    Grassi, J.5    Mabondzo, A.6
  • 30
    • 0037794389 scopus 로고    scopus 로고
    • The brain endothelin system as potential target for brain-related Pathologies
    • Schinelli S. The brain endothelin system as potential target for brain-related Pathologies. Curr Drug Targets CNS Neurol Disord 2002, 6:543-553.
    • (2002) Curr Drug Targets CNS Neurol Disord , vol.6 , pp. 543-553
    • Schinelli, S.1
  • 31
    • 33847094700 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier
    • Bauer B, Hartz AM, Miller DS. Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Mol Pharmacol 2007, 71:667-675.
    • (2007) Mol Pharmacol , vol.71 , pp. 667-675
    • Bauer, B.1    Hartz, A.M.2    Miller, D.S.3
  • 32
    • 0037320253 scopus 로고    scopus 로고
    • Molecular insights on the cerebral innate immune system
    • 10.1016/S0889-1591(02)00055-7, 12615045
    • Rivest S. Molecular insights on the cerebral innate immune system. Brain Behav Immun 2003, 17:13-19. 10.1016/S0889-1591(02)00055-7, 12615045.
    • (2003) Brain Behav Immun , vol.17 , pp. 13-19
    • Rivest, S.1
  • 33
    • 0142185061 scopus 로고    scopus 로고
    • Inflammation in central nervous system injury
    • 10.1098/rstb.2003.1358, 1693261, 14561325
    • Allan SM, Rothwell NJ. Inflammation in central nervous system injury. Philos Trans R Soc Lond B Biol Sci 2003, 358:1669-1677. 10.1098/rstb.2003.1358, 1693261, 14561325.
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , pp. 1669-1677
    • Allan, S.M.1    Rothwell, N.J.2
  • 34
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • Farina C, Aloisi F, Meinl E. Astrocytes are active players in cerebral innate immunity. Trends Immunol 2007, 3:138-145.
    • (2007) Trends Immunol , vol.3 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 35
    • 0026509439 scopus 로고
    • Transcriptional regulation of the endothelin-1 gene by TNF-alpha
    • Marsden PA, Brenner BM. Transcriptional regulation of the endothelin-1 gene by TNF-alpha. Am J Physiol 1992, 262:C854-C861.
    • (1992) Am J Physiol , vol.262
    • Marsden, P.A.1    Brenner, B.M.2
  • 36
    • 0035341326 scopus 로고    scopus 로고
    • Endothelin-1 and monocyte chemoattractant protein-1 modulation in ischemia and human brain-derived endothelial cell cultures
    • 10.1016/S0165-5728(01)00280-6, 11311331
    • Chen P, Shibata M, Zidovetzki R, Fisher M, Zlokovic BV, Hofman FM. Endothelin-1 and monocyte chemoattractant protein-1 modulation in ischemia and human brain-derived endothelial cell cultures. J Neuroimmunol 2001, 116:62-73. 10.1016/S0165-5728(01)00280-6, 11311331.
    • (2001) J Neuroimmunol , vol.116 , pp. 62-73
    • Chen, P.1    Shibata, M.2    Zidovetzki, R.3    Fisher, M.4    Zlokovic, B.V.5    Hofman, F.M.6
  • 37
    • 4944230261 scopus 로고    scopus 로고
    • Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1
    • 10.1124/mol.104.001503, 15322229
    • Hartz AM, Bauer B, Fricker G, Miller DS. Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1. Mol Pharmacol 2004, 66:387-394. 10.1124/mol.104.001503, 15322229.
    • (2004) Mol Pharmacol , vol.66 , pp. 387-394
    • Hartz, A.M.1    Bauer, B.2    Fricker, G.3    Miller, D.S.4
  • 38
    • 21144451475 scopus 로고    scopus 로고
    • Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding
    • 10.1124/jpet.104.079319, 15743928
    • Liu X, Smith BJ, Chen C, Callegari E, Becker SL, Chen X, Cianfrogna J, Doran AC, Doran SD, Gibbs JP, Hosea N, Liu J, Nelson FR, Szewc MA, Van DJ. Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue binding. J Pharmacol Exp Ther 2005, 313:1254-1262. 10.1124/jpet.104.079319, 15743928.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 1254-1262
    • Liu, X.1    Smith, B.J.2    Chen, C.3    Callegari, E.4    Becker, S.L.5    Chen, X.6    Cianfrogna, J.7    Doran, A.C.8    Doran, S.D.9    Gibbs, J.P.10    Hosea, N.11    Liu, J.12    Nelson, F.R.13    Szewc, M.A.14    Van, D.J.15
  • 39
    • 45949107902 scopus 로고    scopus 로고
    • On the rate and extent of drug delivery to the brain
    • 10.1007/s11095-007-9502-2, 2469271, 18058202
    • Hammarlund-Udenaes M, Friden M, Syvanen S, Gupta A. On the rate and extent of drug delivery to the brain. Pharm Res 2008, 25:1737-1750. 10.1007/s11095-007-9502-2, 2469271, 18058202.
    • (2008) Pharm Res , vol.25 , pp. 1737-1750
    • Hammarlund-Udenaes, M.1    Friden, M.2    Syvanen, S.3    Gupta, A.4
  • 40
    • 0003099568 scopus 로고    scopus 로고
    • Neurocellular anatomy
    • Lippincott Williams and Wilkins, Philadelphia, Siegel GJ, Agranoff BW, Albers RW, Fisher SK, Uhler MD, 6
    • Raine CS. Neurocellular anatomy. Basic Neurochemistry: molecular, cellular and medical aspects 1999, 3-30. Lippincott Williams and Wilkins, Philadelphia, Siegel GJ, Agranoff BW, Albers RW, Fisher SK, Uhler MD, 6.
    • (1999) Basic Neurochemistry: molecular, cellular and medical aspects , pp. 3-30
    • Raine, C.S.1
  • 41
    • 0019404014 scopus 로고
    • Evaluation of the dye-protein tracers in pathophysiology of the blood-brain barrier
    • 10.1007/BF00691332, 7234328
    • Wolman M, Klatzo I, Chui E, Wilmes F, Nishimoto K, Fujiwara K, Spatz M. Evaluation of the dye-protein tracers in pathophysiology of the blood-brain barrier. Acta Neuropathol 1981, 54:55-61. 10.1007/BF00691332, 7234328.
    • (1981) Acta Neuropathol , vol.54 , pp. 55-61
    • Wolman, M.1    Klatzo, I.2    Chui, E.3    Wilmes, F.4    Nishimoto, K.5    Fujiwara, K.6    Spatz, M.7
  • 45
    • 61849149792 scopus 로고    scopus 로고
    • Review: role of developmental inflammation and blood-brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases
    • 10.1111/j.1365-2990.2008.01005.x, 19077110
    • Stolp HB, Dziegielewska KM. Review: role of developmental inflammation and blood-brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases. Neuropathol Appl Neurobiol 2009, 35:132-146. 10.1111/j.1365-2990.2008.01005.x, 19077110.
    • (2009) Neuropathol Appl Neurobiol , vol.35 , pp. 132-146
    • Stolp, H.B.1    Dziegielewska, K.M.2
  • 46
    • 0036847816 scopus 로고    scopus 로고
    • Microglia as neuroprotective, immunocompetent cells of the CNS
    • 10.1002/glia.10154, 12379901
    • Streit WJ. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 2002, 40:133-139. 10.1002/glia.10154, 12379901.
    • (2002) Glia , vol.40 , pp. 133-139
    • Streit, W.J.1
  • 47
    • 0036849018 scopus 로고    scopus 로고
    • Microglia as a source and target of cytokines
    • 10.1002/glia.10161, 12379902
    • Hanisch UK. Microglia as a source and target of cytokines. Glia 2002, 40:140-155. 10.1002/glia.10161, 12379902.
    • (2002) Glia , vol.40 , pp. 140-155
    • Hanisch, U.K.1
  • 48
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • 10.1016/0166-2236(96)10049-7, 8843599
    • Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996, 19:312-318. 10.1016/0166-2236(96)10049-7, 8843599.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 49
    • 0031957224 scopus 로고    scopus 로고
    • Microglia, scavenger receptors, and the pathogenesis of Alzheimer's disease
    • 10.1016/S0197-4580(98)00036-0, 9562474
    • El Khoury J, Hickman SE, Thomas CA, Loike JD, Silverstein SC. Microglia, scavenger receptors, and the pathogenesis of Alzheimer's disease. Neurobiol Aging 1998, 19:S81-S84. 10.1016/S0197-4580(98)00036-0, 9562474.
    • (1998) Neurobiol Aging , vol.19
    • El Khoury, J.1    Hickman, S.E.2    Thomas, C.A.3    Loike, J.D.4    Silverstein, S.C.5
  • 50
    • 0035152836 scopus 로고    scopus 로고
    • Immune function of microglia
    • 10.1002/glia.1106, 11596125
    • Aloisi F. Immune function of microglia. Glia 2001, 36:165-179. 10.1002/glia.1106, 11596125.
    • (2001) Glia , vol.36 , pp. 165-179
    • Aloisi, F.1
  • 51
    • 0031024047 scopus 로고    scopus 로고
    • Differential production of and migratory response to beta chemokines by human microglia and astrocytes
    • 10.1093/infdis/175.2.478, 9203678
    • Peterson K, Hu S, Salak-Johnson J, Molitor TW, Chao CC. Differential production of and migratory response to beta chemokines by human microglia and astrocytes. J Infect Dis 1997, 175:478-481. 10.1093/infdis/175.2.478, 9203678.
    • (1997) J Infect Dis , vol.175 , pp. 478-481
    • Peterson, K.1    Hu, S.2    Salak-Johnson, J.3    Molitor, T.W.4    Chao, C.C.5
  • 53
    • 0038348526 scopus 로고    scopus 로고
    • Microglial functions and proteases
    • 10.1385/MN:27:2:163, 12777686
    • Nakanishi H. Microglial functions and proteases. Mol Neurobiol 2003, 27:163-176. 10.1385/MN:27:2:163, 12777686.
    • (2003) Mol Neurobiol , vol.27 , pp. 163-176
    • Nakanishi, H.1
  • 54
    • 0034802570 scopus 로고    scopus 로고
    • Immunological aspects of microglia: relevance to Alzheimer's disease
    • 10.1016/S0197-0186(01)00045-6, 11578773
    • Benveniste EN, Nguyen VT, O'Keefe GM. Immunological aspects of microglia: relevance to Alzheimer's disease. Neurochem Int 2001, 39:381-391. 10.1016/S0197-0186(01)00045-6, 11578773.
    • (2001) Neurochem Int , vol.39 , pp. 381-391
    • Benveniste, E.N.1    Nguyen, V.T.2    O'Keefe, G.M.3
  • 55
    • 67650300497 scopus 로고    scopus 로고
    • Acquired immunodeficiency syndrome and the blood-brain barrier
    • 10.1080/13550280902769764, 2744422, 19306229
    • Ivey NS, MacLean AG, Lackner AA. Acquired immunodeficiency syndrome and the blood-brain barrier. J Neurovirol 2009, 15:111-122. 10.1080/13550280902769764, 2744422, 19306229.
    • (2009) J Neurovirol , vol.15 , pp. 111-122
    • Ivey, N.S.1    MacLean, A.G.2    Lackner, A.A.3
  • 56
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: cellular and molecular cues to biological function
    • 10.1016/S0166-2236(97)01139-9, 9416670
    • Ridet JL, Malhotra SK, Privat A, Gage FH. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 1997, 20:570-577. 10.1016/S0166-2236(97)01139-9, 9416670.
    • (1997) Trends Neurosci , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 58
    • 34547902120 scopus 로고    scopus 로고
    • Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P-glycoprotein
    • 10.1111/j.1471-4159.2007.04644.x, 17697052
    • Seelbach MJ, Brooks TA, Egleton RD, Davis TP. Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P-glycoprotein. J Neurochem 2007, 102:1677-1690. 10.1111/j.1471-4159.2007.04644.x, 17697052.
    • (2007) J Neurochem , vol.102 , pp. 1677-1690
    • Seelbach, M.J.1    Brooks, T.A.2    Egleton, R.D.3    Davis, T.P.4
  • 59
    • 0345688182 scopus 로고    scopus 로고
    • Transcriptional regulation of ABC drug transporters
    • 10.1038/sj.onc.1206950, 14576854
    • Scotto KW. Transcriptional regulation of ABC drug transporters. Oncogene 2003, 22:7496-7511. 10.1038/sj.onc.1206950, 14576854.
    • (2003) Oncogene , vol.22 , pp. 7496-7511
    • Scotto, K.W.1
  • 60
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: structural, cellular, and molecular biology
    • 10.1146/annurev.biochem.69.1.145, 10966456
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 2000, 69:145-182. 10.1146/annurev.biochem.69.1.145, 10966456.
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 61
    • 1442301504 scopus 로고    scopus 로고
    • Cyclooxygenase-2: potential role in regulation of drug efflux and multidrug resistance phenotype
    • Sorokin A. Cyclooxygenase-2: potential role in regulation of drug efflux and multidrug resistance phenotype. Curr Pharm 2004, 10:647-657.
    • (2004) Curr Pharm , vol.10 , pp. 647-657
    • Sorokin, A.1
  • 62
    • 0344393071 scopus 로고    scopus 로고
    • Signalling pathways influencing basal and H(2)O(2)-induced P-glycoprotein expression in endothelial cells derived from the blood-brain barrier
    • Nwaozuzu OM, Sellers LA, Barrand MA. Signalling pathways influencing basal and H(2)O(2)-induced P-glycoprotein expression in endothelial cells derived from the blood-brain barrier. J Neurochem 2003, 87:1043-1051.
    • (2003) J Neurochem , vol.87 , pp. 1043-1051
    • Nwaozuzu, O.M.1    Sellers, L.A.2    Barrand, M.A.3
  • 63
    • 33744483102 scopus 로고    scopus 로고
    • P-glycoprotein and 'lipid rafts': some ambiguous mutual relationships (floating on them, building them or meeting them by chance?)
    • 10.1007/s00018-005-5554-9, 16721513
    • Orlowski S, Martin S, Escargueil A. P-glycoprotein and 'lipid rafts': some ambiguous mutual relationships (floating on them, building them or meeting them by chance?). Cell Mol Life Sci 2006, 63:1038-1059. 10.1007/s00018-005-5554-9, 16721513.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 1038-1059
    • Orlowski, S.1    Martin, S.2    Escargueil, A.3


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