Glutamate-mediated upregulation of the multidrug resistance protein 2 in porcine and human brain capillaries

Journal of Pharmacology and Experimental Therapeutics

Volumn 352, Issue 2, 2015, Pages 368-378

  Luna Munguia, Hiram ^a   Salvamoser, Josephine D ^a   Pascher, Bettina ^b   Pieper, Tom ^b   Getzinger, Thekla ^b   Kudernatsch, Manfred ^c   Kluger, Gerhard ^b,d   Potschka, Heidrun ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Epilepsy Center for Children and Adolescents   (Germany)

^c Schon Klinik Vogtareuth   (Germany)

^d PARACELSUS MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

7 CHLORO 4 HYDROXY 3 (3 PHENOXYPHENYL) 2 QUINOLONE; CELECOXIB; CYCLOOXYGENASE 2; DIZOCILPINE; GLUCOSE TRANSPORTER 1; GLUTAMIC ACID; INDOMETACIN; MULTIDRUG RESISTANCE PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; MULTIDRUG RESISTANCE PROTEIN; P-GLYCOPROTEIN 2;

ANIMAL TISSUE; ARTICLE; BRAIN CAPILLARY; CONTROLLED STUDY; DOWN REGULATION; DRUG EXPOSURE; DRUG MIXTURE; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME INHIBITION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; ISOLATED ORGAN; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SWINE; TISSUE DISTRIBUTION; TRANSLATIONAL RESEARCH; UPREGULATION; ADOLESCENT; ANIMAL; BIOSYNTHESIS; BLOOD BRAIN BARRIER; BRAIN; CAPILLARY; CHILD; DOSE RESPONSE; DRUG EFFECTS; EPILEPSY; FEMALE; IN VITRO STUDY; MALE; METABOLISM; PIG; PRESCHOOL CHILD; TRANSPORT AT THE CELLULAR LEVEL; VASCULARIZATION;

ADOLESCENT; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARIES; CHILD; CHILD, PRESCHOOL; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY; FEMALE; GLUTAMIC ACID; HUMANS; IN VITRO TECHNIQUES; MALE; P-GLYCOPROTEINS; RECEPTORS, N-METHYL-D-ASPARTATE; SWINE; UP-REGULATION;

EID: 84921278525     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.218180     Document Type: Article

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