Elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus

Epilepsy Research

Volumn 54, Issue 1, 2003, Pages 73-79

  Thomas, P M ^a,b   Phillips, J P ^a   Delanty, N ^a   O'Connor, W T ^b  

^a BEAUMONT HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Aspartate; Gamma aminobutyric acid; Glutamate; Hippocampus; Microdialysis; Temporal lobe epilepsy surgery

Indexed keywords

4 AMINOBUTYRIC ACID; ASPARTIC ACID; GLUTAMIC ACID;

ADULT; ARTICLE; BRAIN SURGERY; CASE REPORT; CELL LEVEL; DIALYSATE LEVEL; ELECTROCORTICOGRAPHY; EPILEPTIC DISCHARGE; EXTRACELLULAR SPACE; FEMALE; HIPPOCAMPUS; HUMAN; INTRAOPERATIVE PERIOD; MALE; MICRODIALYSIS; PRIORITY JOURNAL; TEMPORAL LOBE EPILEPSY; TISSUE LEVEL;

EID: 0038059134     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(03)00035-4     Document Type: Article

References (28)

1. Amberg G., Lindefors N. Intracerebral microdialysis: II. Mathematical studies of diffusion kinetics. J. Pharmacol. 22:1989;157-183.
2. Benveniste H. Brain microdialysis. J. Neurochem. 52:1989;1667-1679.
3. Carreño, M., Lüders, H.O., 2001. General principles of presurgical evaluation. In: Lüders, H.O., Comair, Y.G. (Eds.), Epilepsy Surgery. Lippincott Williams and Wilkins, Philadelphia, pp. 185-199.
4. Chatrian, G.-E., Quesney, L.F., 1997. Intraoperative electrocorticography. In: Engel, J. Jr., Pedley, T.A. (Eds.), Epilepsy: A Comprehensive Textbook. Lippincott-Raven, Philadelphia, pp. 1749-1765.
5. Chen G., Ewing A.G. Chemical analysis of single cells and exocytosis. Crit. Rev. Neurobiol. 11:1997;59-90.
6. Dingledine, R., McBain, C.J., 1999. Glutamate and aspartate. In: Siegel, G.J., Agranoff, B.W., Albers, R.W., Fisher, S.K., Uhler, M.D. (Eds.), Basic Neurochemistry: Molecular, Cellular and Medical Aspects. Lippincott-Raven, Philadelphia, pp. 315-333.
7. During, M.J., 1991. In vivo neurochemistry of the conscious human brain: intrahippocampal microdialysis in epilepsy. In: Robinson, T.E., Justice, J.B. (Eds.), Microdialysis in the Neurosciences. Elsevier, Amsterdam, pp. 425-442.
8. During M.J., Spencer D.D. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet. 341:1993;1607-1610.
9. Fried I., Wilson C., Maidment N.T., Engel J. Jr., Behnke E., Fields T.A., MacDonald K.A., Morrow J.W., Ackerson L. Cerebral microdialysis combined with single-neuron and electroencephalographic recording in neurosurgical patients. J. Neurosurg. 91:1999;697-705.
10. Gloor, P., 1975. Contributions of electroencephalography and electrocorticography to the neurosurgical treatment of the epilepsies. In: Purpura, D., Penry, J., Walter, R. (Eds.), Neurosurgical Management of the Epilepsies. Raven Press, New York, pp. 59-105.
11. Hillered L., Persson L. Theory and practice of microdialysis - prospects for future clinical use. Acta Neurochir. 75(Suppl):1999a;3-6.
12. Hillered L., Persson L. Neurochemical monitoring of the acutely injured human brain. Scand. J. Clin. Lab. Invest. 59(Suppl. 229):1999b;9-18.
13. Kim, R., Spencer, D., 2001. Surgery for mesial temporal sclerosis. In: Lüders, H.O., Comair, Y.G. (Eds.), Epilepsy Surgery. Lippincott Williams and Wilkins, Philadelphia, pp. 643-652.
14. Kulagina N.V., Shankar L., Michael A.C. Monitoring glutamate and ascorbate in the extracellular space of brain tissue with electrochemical microsensors. Anal. Chem. 71:1999;5093-5100.
15. Lazarewicz J.W., Hagberg H., Hamberger A. Extracellular calcium in the hippocampus of unanesthetized rabbits monitored with dialysis-perfusion. J. Neurosci. Methods. 15:1986;317-328.
16. Longman M.J., Budygin E., Gainetdinov R.R., Wightman R.M. Quantitation of in vivo measurements with carbon fibre microelectrodes. J. Neurosci. Methods. 95:2000;95-102.
17. McKhann G.M. II, Schoenfeld-McNeill J., Born D.E., Haglund M.M., Ojemann G.A. Intraoperative hippocampal electrocorticography to predict the extent of hippocampal resection in temporal lobe epilepsy surgery. J. Neurosurg. 93:2000;44-52.
18. Meyerson B.A., Linderoth B., Karlsson H., Ungerstedt U. Extracellular measurements in the thalamus of parkinsonian patients. Life Sci. 46:1990;301-308.
19. Morari M., O'Connor W.T., Ungerstedt U., Fuxe K. Dopamine D1 and D2 receptor antagonism differentially modulates stimulation of striatal neurotransmitter levels by N-methyl-D-aspartic acid. Eur. J. Pharmacol. 256:1994;23-30.
20. Niemeyer, P., 1958. The transventricular amygdala-hippocampectomy in temporal lobe epilepsy. In: Baldwin, M., Bailey, P. (Eds.), Temporal Lobe Epilepsy. Thomas, Springfield, pp. 461-482.
21. Olsen, R.W., DeLorey, T.M., 1999. GABA and glycine. In: Siegel, G.J., Agranoff, B.W., Albers, R.W., Fisher, S.K., Uhler, M.D. (Eds.), Basic Neurochemistry: Molecular, Cellular and Medical Aspects. Lippincott-Raven, Philadelphia, pp. 335-346.
22. Reinstrup P., Ståhl N., Mellegård P., Uski T., Ungerstedt U., Nordström C.-H. Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery. Neurosurgery. 47:2000;701-710.
23. Ronne-Engström E., Hillered L., Flink R., Spännare B., Ungerstedt U., Carlson H. Intracerebral microdialysis of extracellular amino acids in the human epileptic focus. J. Cereb. Blood Flow Metab. 12:1992;873-876.
24. Schubert, A., 2001. Anesthesia for epilepsy surgery. In: Lüders, H.O., Comair, Y.G. (Eds.), Epilepsy Surgery. Lippincott Williams and Wilkins, Philadelphia, pp. 623-631.
25. Wennberg R., Quesney F., Villemure J.-G. Epileptiform and non-epileptiform paroxysmal activity from isolated cortex after functional hemispherectomy. Electroencephalogr. Clin. Neurophysiol. 102:1997;437-442.
26. Wilson C.L., Maidment N.T., Shomer M.H., Behnke E.J., Ackerson L., Fried I., Engel J. Jr. Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic kainite rat model of hippocampal epilepsy. Epilepsy Res. 26:1996;245-254.
27. Wyler A.R., Dohan F.C. Jr., Sshweitzer J.B., Berry A.D. III A grading system for mesial temporal pathology (hippocampal sclerosis) from anterior temporal lobectomy. J. Epilepsy. 5:1992;220-225.
28. Zhou M., Peterson C.L., Lu Y.B., Nadler J.V. Release of glutamate and aspartate from CA1 synaptosomes: selective modulation of aspartate release by ionotropic glutamate receptor ligands. J. Neurochem. 64:1995;1556-1566.