-
1
-
-
84901677114
-
Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma
-
Kakiuchi M, Nishizawa T, Ueda H, et al. Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma. Nat Genet 2014; 46: 583-7.
-
(2014)
Nat Genet
, vol.46
, pp. 583-587
-
-
Kakiuchi, M.1
Nishizawa, T.2
Ueda, H.3
-
2
-
-
84901680089
-
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
-
Wang K, Yuen ST, Xu J, et al. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Nat Genet 2014; 46: 573-82.
-
(2014)
Nat Genet
, vol.46
, pp. 573-582
-
-
Wang, K.1
Yuen, S.T.2
Xu, J.3
-
3
-
-
82255183148
-
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
-
Wang K, Kan J, Yuen ST, et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat Genet 2011; 43: 1219-23.
-
(2011)
Nat Genet
, vol.43
, pp. 1219-1223
-
-
Wang, K.1
Kan, J.2
Yuen, S.T.3
-
4
-
-
82255192291
-
A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1
-
Shi Y, Hu Z, Wu C, et al. A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. Nat Genet 2011; 43: 1215-8.
-
(2011)
Nat Genet
, vol.43
, pp. 1215-1218
-
-
Shi, Y.1
Hu, Z.2
Wu, C.3
-
5
-
-
84860327480
-
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
-
Zang ZJ, Cutcutache I, Poon SL, et al. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat Genet 2012.
-
(2012)
Nat Genet
-
-
Zang, Z.J.1
Cutcutache, I.2
Poon, S.L.3
-
6
-
-
84870875221
-
Whole-genome reconstruction and mutational signatures in gastric cancer
-
Nagarajan N, Bertrand D, Hillmer AM, et al. Whole-genome reconstruction and mutational signatures in gastric cancer. Genome Biol 2012; 13: R115.
-
(2012)
Genome Biol
, vol.13
, pp. R115
-
-
Nagarajan, N.1
Bertrand, D.2
Hillmer, A.M.3
-
7
-
-
79955555195
-
Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes
-
Hillmer AM, Yao F, Inaki K, et al. Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes. Genome Res 2011; 21: 665-75.
-
(2011)
Genome Res
, vol.21
, pp. 665-675
-
-
Hillmer, A.M.1
Yao, F.2
Inaki, K.3
-
8
-
-
74949138753
-
Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
-
Drmanac R, Sparks AB, Callow MJ, et al. Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science 2010; 327: 78-81.
-
(2010)
Science
, vol.327
, pp. 78-81
-
-
Drmanac, R.1
Sparks, A.B.2
Callow, M.J.3
-
9
-
-
77955405475
-
Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor
-
McLaren W, Pritchard B, Rios D, et al. Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor. Bioinformatics 2010; 26: 2069-70.
-
(2010)
Bioinformatics
, vol.26
, pp. 2069-2070
-
-
McLaren, W.1
Pritchard, B.2
Rios, D.3
-
10
-
-
84930416067
-
-
UCSC
-
UCSC. http://hgdownload.cse.ucsc.edu/goldenPath/hg19/gc5Base/hg19.gc5Base.txt.gz.
-
-
-
-
11
-
-
34147104969
-
A faster circular binary segmentation algorithm for the analysis of array CGH data
-
Venkatraman ES, Olshen AB,. A faster circular binary segmentation algorithm for the analysis of array CGH data. Bioinformatics 2007; 23: 657-63.
-
(2007)
Bioinformatics
, vol.23
, pp. 657-663
-
-
Venkatraman, E.S.1
Olshen, A.B.2
-
12
-
-
79952356464
-
An integrated transcriptomic and computational analysis for biomarker identification in gastric cancer
-
Cui J, Chen Y, Chou WC, et al. An integrated transcriptomic and computational analysis for biomarker identification in gastric cancer. Nucleic Acids Res 2011; 39: 1197-207.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1197-1207
-
-
Cui, J.1
Chen, Y.2
Chou, W.C.3
-
13
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger MF, Lawrence MS, Demichelis F, et al. The genomic complexity of primary human prostate cancer. Nature 2011; 470: 214-20.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
Lawrence, M.S.2
Demichelis, F.3
-
14
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z, Jaiswal BS, Stinson J, et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 2010; 466: 869-73.
-
(2010)
Nature
, vol.466
, pp. 869-873
-
-
Kan, Z.1
Jaiswal, B.S.2
Stinson, J.3
-
15
-
-
74449085934
-
A small-cell lung cancer genome with complex signatures of tobacco exposure
-
Pleasance ED, Stephens PJ, O'Meara S, et al. A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature 2010; 463: 184-90.
-
(2010)
Nature
, vol.463
, pp. 184-190
-
-
Pleasance, E.D.1
Stephens, P.J.2
O'Meara, S.3
-
16
-
-
74449093973
-
A comprehensive catalogue of somatic mutations from a human cancer genome
-
Pleasance ED, Cheetham RK, Stephens PJ, et al. A comprehensive catalogue of somatic mutations from a human cancer genome. Nature 2010; 463: 191-6.
-
(2010)
Nature
, vol.463
, pp. 191-196
-
-
Pleasance, E.D.1
Cheetham, R.K.2
Stephens, P.J.3
-
17
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C, Stephens P, Smith R, et al. Patterns of somatic mutation in human cancer genomes. Nature 2007; 446: 153-8.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
-
18
-
-
3843084078
-
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
-
Bamford S, Dawson E, Forbes S, et al. The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer 2004; 91: 355-8.
-
(2004)
Br J Cancer
, vol.91
, pp. 355-358
-
-
Bamford, S.1
Dawson, E.2
Forbes, S.3
-
19
-
-
0037474527
-
A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle
-
Yang JJ,. A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle. Biochem Biophys Res Commun 2003; 301: 71-7.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 71-77
-
-
Yang, J.J.1
-
20
-
-
77954156988
-
ZAK inhibits human lung cancer cell growth via ERK and JNK activation in an AP-1-dependent manner
-
Yang JJ, Lee YJ, Hung HH, et al. ZAK inhibits human lung cancer cell growth via ERK and JNK activation in an AP-1-dependent manner. Cancer Sci 2010; 101: 1374-81.
-
(2010)
Cancer Sci
, vol.101
, pp. 1374-1381
-
-
Yang, J.J.1
Lee, Y.J.2
Hung, H.H.3
-
21
-
-
77950551052
-
Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays
-
Wang J, Ramakrishnan R, Tang Z, et al. Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays. Clin Chem 2010; 56: 623-32.
-
(2010)
Clin Chem
, vol.56
, pp. 623-632
-
-
Wang, J.1
Ramakrishnan, R.2
Tang, Z.3
-
22
-
-
0032542697
-
Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: Association with human papillomavirus type
-
Muller CY, O'Boyle JD, Fong KM, et al. Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: association with human papillomavirus type. J Natl Cancer Inst 1998; 90: 433-9.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 433-439
-
-
Muller, C.Y.1
O'Boyle, J.D.2
Fong, K.M.3
-
24
-
-
59249105978
-
A microhomology-mediated break-induced replication model for the origin of human copy number variation
-
Hastings PJ, Ira G, Lupski JR,. A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet 2009; 5: e1000327.
-
(2009)
PLoS Genet
, vol.5
, pp. e1000327
-
-
Hastings, P.J.1
Ira, G.2
Lupski, J.R.3
-
25
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
Stephens PJ, McBride DJ, Lin ML, et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009; 462: 1005-10.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
McBride, D.J.2
Lin, M.L.3
-
26
-
-
70349873824
-
Comprehensive mapping of long-range interactions reveals folding principles of the human genome
-
Lieberman-Aiden E, van Berkum NL, Williams L, et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009; 326: 289-93.
-
(2009)
Science
, vol.326
, pp. 289-293
-
-
Lieberman-Aiden, E.1
Van Berkum, N.L.2
Williams, L.3
-
27
-
-
84861095603
-
Topological domains in mammalian genomes identified by analysis of chromatin interactions
-
Dixon JR, Selvaraj S, Yue F, et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 2012; 485: 376-80.
-
(2012)
Nature
, vol.485
, pp. 376-380
-
-
Dixon, J.R.1
Selvaraj, S.2
Yue, F.3
-
28
-
-
83255174075
-
Genomic rearrangement in three dimensions
-
Hastings PJ, Rosenberg SM,. Genomic rearrangement in three dimensions. Nat Biotechnol 2011; 29: 1096-8.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 1096-1098
-
-
Hastings, P.J.1
Rosenberg, S.M.2
-
30
-
-
30144439370
-
Common fragile sites
-
Glover TW,. Common fragile sites. Cancer Lett 2006; 232: 4-12.
-
(2006)
Cancer Lett
, vol.232
, pp. 4-12
-
-
Glover, T.W.1
-
31
-
-
80052607184
-
Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells
-
Toller IM, Neelsen KJ, Steger M, et al. Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proc Natl Acad Sci USA 2011; 108: 14944-9.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14944-14949
-
-
Toller, I.M.1
Neelsen, K.J.2
Steger, M.3
-
32
-
-
69949170092
-
Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a
-
Fine B, Hodakoski C, Koujak S, et al. Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. Science 2009; 325: 1261-5.
-
(2009)
Science
, vol.325
, pp. 1261-1265
-
-
Fine, B.1
Hodakoski, C.2
Koujak, S.3
-
33
-
-
84861427327
-
Melanoma genome sequencing reveals frequent PREX2 mutations
-
Berger MF, Hodis E, Heffernan TP, et al. Melanoma genome sequencing reveals frequent PREX2 mutations. Nature 2012; 485: 502-6.
-
(2012)
Nature
, vol.485
, pp. 502-506
-
-
Berger, M.F.1
Hodis, E.2
Heffernan, T.P.3
-
35
-
-
0038322051
-
JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis
-
Chang NS, Doherty J, Ensign A,. JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis. J Biol Chem 2003; 278: 9195-202.
-
(2003)
J Biol Chem
, vol.278
, pp. 9195-9202
-
-
Chang, N.S.1
Doherty, J.2
Ensign, A.3
-
36
-
-
79953231260
-
Phosphorylation of the anaphase-promoting complex/Cdc27 is involved in TGF-beta signaling
-
Zhang L, Fujita T, Wu G, et al. Phosphorylation of the anaphase-promoting complex/Cdc27 is involved in TGF-beta signaling. J Biol Chem 2011; 286: 10041-50.
-
(2011)
J Biol Chem
, vol.286
, pp. 10041-10050
-
-
Zhang, L.1
Fujita, T.2
Wu, G.3
-
37
-
-
77952718207
-
C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression
-
Pawar SA, Sarkar TR, Balamurugan K, et al. C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression. Proc Natl Acad Sci USA 2010; 107: 9210-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9210-9215
-
-
Pawar, S.A.1
Sarkar, T.R.2
Balamurugan, K.3
-
39
-
-
77955819117
-
Significance of mucin expression in pancreatobiliary neoplasms
-
Yonezawa S, Higashi M, Yamada N, et al. Significance of mucin expression in pancreatobiliary neoplasms. J Hepatobiliary Pancreat Sci 2010; 17: 108-24.
-
(2010)
J Hepatobiliary Pancreat Sci
, vol.17
, pp. 108-124
-
-
Yonezawa, S.1
Higashi, M.2
Yamada, N.3
-
40
-
-
10644274393
-
Effects of pH on Helicobacter pylori binding to human gastric mucins: Identification of binding to non-MUC5AC mucins
-
Linden S, Mahdavi J, Hedenbro J, et al. Effects of pH on Helicobacter pylori binding to human gastric mucins: identification of binding to non-MUC5AC mucins. Biochem J 2004; 384: 263-70.
-
(2004)
Biochem J
, vol.384
, pp. 263-270
-
-
Linden, S.1
Mahdavi, J.2
Hedenbro, J.3
-
41
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA,. The hallmarks of cancer. Cell 2000; 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
42
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
Cancer Genome Atlas Research N.
-
Cancer Genome Atlas Research N,. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014; 513: 202-9.
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
43
-
-
0034051262
-
Helicobacter pylori causes DNA damage in gastric epithelial cells
-
Obst B, Wagner S, Sewing KF, Beil W,. Helicobacter pylori causes DNA damage in gastric epithelial cells. Carcinogenesis 2000; 21: 1111-5.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1111-1115
-
-
Obst, B.1
Wagner, S.2
Sewing, K.F.3
Beil, W.4
-
44
-
-
84861902303
-
Hypoxia and miscoupling between reduced energy efficiency and signaling to cell proliferation drive cancer to grow increasingly faster
-
Cui J, Mao X, Olman V, et al. Hypoxia and miscoupling between reduced energy efficiency and signaling to cell proliferation drive cancer to grow increasingly faster. J Mol Cell Biol 2012; 4: 174-6.
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 174-176
-
-
Cui, J.1
Mao, X.2
Olman, V.3
|