-
1
-
-
34247348182
-
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia
-
DOI 10.1182/blood-2006-08-040147
-
Agrawal S, et al. (2007) The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. Blood 109:3895-3905. (Pubitemid 46641742)
-
(2007)
Blood
, vol.109
, Issue.9
, pp. 3895-3905
-
-
Agrawal, S.1
Hofmann, W.-K.2
Tidow, N.3
Ehrich, M.4
Van Den Boom, D.5
Koschmieder, S.6
Berdel, W.E.7
Serve, H.8
Muller-Tidow, C.9
-
2
-
-
57649221599
-
Epigenetic silencing of CCAAT/ enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex
-
Ko CY, Hsu HC, Shen MR, Chang WC, Wang JM (2008) Epigenetic silencing of CCAAT/ enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. J Biol Chem 283:30919-30932.
-
(2008)
J Biol Chem
, vol.283
, pp. 30919-30932
-
-
Ko, C.Y.1
Hsu, H.C.2
Shen, M.R.3
Chang, W.C.4
Wang, J.M.5
-
3
-
-
0037361170
-
Molecular markers in ductal carcinoma in situ of the breast
-
Porter D, et al. (2003) Molecular markers in ductal carcinoma in situ of the breast. Mol Cancer Res 1:362-375. (Pubitemid 36437922)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.5
, pp. 362-375
-
-
Porter, D.1
Lahti-Domenici, J.2
Keshaviah, A.3
Bae, Y.K.4
Argani, P.5
Marks, J.6
Richardson, A.7
Cooper, A.8
Strausberg, R.9
Riggins, G.J.10
Schnitt, S.11
Gabrielson, E.12
Gelman, R.13
Polyak, K.14
-
4
-
-
33645223741
-
Promoter methylation reduces C/EBPdelta (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors
-
Tang D, Sivko GS, DeWille JW (2006) Promoter methylation reduces C/EBPdelta (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors. Breast Cancer Res Treat 95:161-170.
-
(2006)
Breast Cancer Res Treat
, vol.95
, pp. 161-170
-
-
Tang, D.1
Sivko, G.S.2
Dewille, J.W.3
-
5
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, et al. (2006) A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10:515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
-
6
-
-
0033523116
-
0 growth arrest and apoptosis
-
O'Rourke JP, Newbound GC, Hutt JA, DeWille J (1999) CCAAT/enhancer- binding protein delta regulates mammary epithelial cell G0 growth arrest and apoptosis. J Biol Chem 274:16582-16589. (Pubitemid 129526418)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.23
, pp. 16582-16589
-
-
O'Rourke, J.P.1
Newbound, G.C.2
Hutt, J.A.3
Dewille, J.4
-
7
-
-
14944358752
-
C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation
-
DOI 10.1038/sj.onc.1208393
-
Gery S, Tanosaki S, Hofmann WK, Koppel A, Koeffler HP (2005) C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation. Oncogene 24:1589-1597. (Pubitemid 40396088)
-
(2005)
Oncogene
, vol.24
, Issue.9
, pp. 1589-1597
-
-
Gery, S.1
Tanosaki, S.2
Hofmann, W.-K.3
Koppel, A.4
Koeffler, H.P.5
-
8
-
-
19644365071
-
3 in androgen-responsive prostate cancer LNCaP cells
-
DOI 10.1158/0008-5472.CAN-03-3619
-
Ikezoe T, et al. (2005) CCAAT/enhancer-binding protein delta: A molecular target of 1,25-dihydroxyvitamin D3 in androgen-responsive prostate cancer LNCaP cells. Cancer Res 65:4762-4768. (Pubitemid 40740813)
-
(2005)
Cancer Research
, vol.65
, Issue.11
, pp. 4762-4768
-
-
Ikezoe, T.1
Gery, S.2
Yin, D.3
O'Kelly, J.4
Binderup, L.5
Lemp, N.6
Taguchi, H.7
Koeffler, H.P.8
-
9
-
-
1542636444
-
Loss of CCAAT/enhancer binding protein δ promotes chromosomal instability
-
Huang AM, et al. (2004) Loss of CCAAT/enhancer binding protein δ promotes chromosomal instability. Oncogene 23:1549-1557.
-
(2004)
Oncogene
, vol.23
, pp. 1549-1557
-
-
Huang, A.M.1
-
10
-
-
77950457650
-
The cell growth inhibitory transcription factor C/EBPdelta is expressed in human meningiomas in association with low histological grade and proliferation index
-
Barresi V, Vitarelli E, Cerasoli S, Barresi G (2010) The cell growth inhibitory transcription factor C/EBPdelta is expressed in human meningiomas in association with low histological grade and proliferation index. J Neurooncol 97:233-240.
-
(2010)
J Neurooncol
, vol.97
, pp. 233-240
-
-
Barresi, V.1
Vitarelli, E.2
Cerasoli, S.3
Barresi, G.4
-
11
-
-
33847348449
-
A gene-expression signature to predict survival in breast cancer across independent data sets
-
DOI 10.1038/sj.onc.1209920, PII 1209920
-
Naderi A, et al. (2007) A gene-expression signature to predict survival in breast cancer across independent data sets. Oncogene 26:1507-1516. (Pubitemid 46340809)
-
(2007)
Oncogene
, vol.26
, Issue.10
, pp. 1507-1516
-
-
Naderi, A.1
Teschendorff, A.E.2
Barbosa-Morais, N.L.3
Pinder, S.E.4
Green, A.R.5
Powe, D.G.6
Robertson, J.F.R.7
Aparicio, S.8
Ellis, I.O.9
Brenton, J.D.10
Caldas, C.11
-
12
-
-
28044433647
-
C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution
-
DOI 10.1242/dev.02050
-
Thangaraju M, et al. (2005) C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution. Development 132:4675-4685. (Pubitemid 41685278)
-
(2005)
Development
, vol.132
, Issue.21
, pp. 4675-4685
-
-
Thangaraju, M.1
Rudelius, M.2
Bierie, B.3
Raffeld, M.4
Sharan, S.5
Hennighausen, L.6
Huang, A.-M.7
Sterneck, E.8
-
13
-
-
33751182887
-
Cyclin D1 and breast cancer
-
Roy PG, Thompson AM (2006) Cyclin D1 and breast cancer. Breast 15:718-727.
-
(2006)
Breast
, vol.15
, pp. 718-727
-
-
Roy, P.G.1
Thompson, A.M.2
-
14
-
-
0028243879
-
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
-
DOI 10.1038/369669a0
-
Wang TC, et al. (1994) Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369:669-671. (Pubitemid 24199473)
-
(1994)
Nature
, vol.369
, Issue.6482
, pp. 669-671
-
-
Wang, T.C.1
Cardiff, R.D.2
Zukerberg, L.3
Lees, E.4
Arnold, A.5
Schmidt, E.V.6
-
15
-
-
0035963435
-
Specific protection against breast cancers by cyclin D1 ablation
-
DOI 10.1038/35082500
-
Yu Q, Geng Y, Sicinski P (2001) Specific protection against breast cancers by cyclin D1 ablation. Nature 411:1017-1021. (Pubitemid 32612319)
-
(2001)
Nature
, vol.411
, Issue.6841
, pp. 1017-1021
-
-
Yu, Q.1
Geng, Y.2
Sicinski, P.3
-
16
-
-
33645278944
-
Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: Effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression
-
Grillo M, et al. (2006) Validation of cyclin D1/CDK4 as an anticancer drug target in MCF-7 breast cancer cells: Effect of regulated overexpression of cyclin D1 and siRNA-mediated inhibition of endogenous cyclin D1 and CDK4 expression. Breast Cancer Res Treat 95:185-194.
-
(2006)
Breast Cancer Res Treat
, vol.95
, pp. 185-194
-
-
Grillo, M.1
-
17
-
-
0038350876
-
Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein α
-
DOI 10.1074/jbc.M300417200
-
Miller M, Shuman JD, Sebastian T, Dauter Z, Johnson PF (2003) Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/ enhancer-binding protein alpha. J Biol Chem 278:15178-15184. (Pubitemid 36799852)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.17
, pp. 15178-15184
-
-
Miller, M.1
Shuman, J.D.2
Sebastian, T.3
Dauter, Z.4
Johnson, P.F.5
-
18
-
-
57349191639
-
Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability
-
Pontano LL, et al. (2008) Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability. Mol Cell Biol 28:7245-7258.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7245-7258
-
-
Pontano, L.L.1
-
19
-
-
48449090686
-
DNA replication stalling attenuates tyrosine kinase signaling to suppress S phase progression
-
Shields BJ, Hauser C, Bukczynska PE, Court NW, Tiganis T (2008) DNA replication stalling attenuates tyrosine kinase signaling to suppress S phase progression. Cancer Cell 14:166-179.
-
(2008)
Cancer Cell
, vol.14
, pp. 166-179
-
-
Shields, B.J.1
Hauser, C.2
Bukczynska, P.E.3
Court, N.W.4
Tiganis, T.5
-
20
-
-
57149136324
-
GammaH2AX and cancer
-
Bonner WM, et al. (2008) GammaH2AX and cancer. Nat Rev Cancer 8:957-967.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 957-967
-
-
Bonner, W.M.1
-
21
-
-
77950961695
-
GammaH2AX: A sensitive molecular marker of DNA damage and repair
-
Mah LJ, El-Osta A, Karagiannis TC (2010) gammaH2AX: A sensitive molecular marker of DNA damage and repair. Leukemia 24:679-686.
-
(2010)
Leukemia
, vol.24
, pp. 679-686
-
-
Mah, L.J.1
El-Osta, A.2
Karagiannis, T.C.3
-
22
-
-
34247149015
-
The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention
-
Alao JP (2007) The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention. Mol Cancer 6:24.
-
(2007)
Mol Cancer
, vol.6
, pp. 24
-
-
Alao, J.P.1
-
23
-
-
0042354669
-
A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer
-
Lamb J, et al. (2003) A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer. Cell 114:323-334.
-
(2003)
Cell
, vol.114
, pp. 323-334
-
-
Lamb, J.1
-
24
-
-
0034616913
-
Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage
-
Agami R, Bernards R (2000) Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage. Cell 102:55-66.
-
(2000)
Cell
, vol.102
, pp. 55-66
-
-
Agami, R.1
Bernards, R.2
-
25
-
-
0029004815
-
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
-
King RW, et al. (1995) A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81:279-288.
-
(1995)
Cell
, vol.81
, pp. 279-288
-
-
King, R.W.1
-
26
-
-
39149123492
-
E3 ubiquitin ligases and mitosis: Embracing the complexity
-
Sumara I, Maerki S, Peter M (2008) E3 ubiquitin ligases and mitosis: Embracing the complexity. Trends Cell Biol 18:84-94.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 84-94
-
-
Sumara, I.1
Maerki, S.2
Peter, M.3
-
27
-
-
33747589184
-
The anaphase promoting complex/cyclosome: A machine designed to destroy
-
Peters JM (2006) The anaphase promoting complex/cyclosome: A machine designed to destroy. Nat Rev Mol Cell Biol 7:644-656.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 644-656
-
-
Peters, J.M.1
-
28
-
-
57349143530
-
Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy
-
Luo J (2009) Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. Cancer Lett 273:194-200.
-
(2009)
Cancer Lett
, vol.273
, pp. 194-200
-
-
Luo, J.1
-
29
-
-
73849129220
-
The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression
-
Wäsch R, Robbins JA, Cross FR (2010) The emerging role of APC/CCdh1 in controlling differentiation, genomic stability and tumor suppression. Oncogene 29:1-10.
-
(2010)
Oncogene
, vol.29
, pp. 1-10
-
-
Wäsch, R.1
Robbins, J.A.2
Cross, F.R.3
-
30
-
-
0042971664
-
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation
-
Wang C, et al. (2003) Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Mol Cell Biol 23:6159-6173.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6159-6173
-
-
Wang, C.1
-
31
-
-
0031937638
-
Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase- independent mechanism
-
InoueK, Sherr CJ (1998)Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism. Mol Cell Biol 18:1590-1600.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1590-1600
-
-
Inoue, K.1
Sherr, C.J.2
-
32
-
-
13244256871
-
A central domain of cyclin D1 mediates nuclear receptor corepressor activity
-
Petre-Draviam CE, et al. (2005) A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene 24:431-444.
-
(2005)
Oncogene
, vol.24
, pp. 431-444
-
-
Petre-Draviam, C.E.1
-
33
-
-
70549105793
-
Control of cell growth by the SCF and APC/C ubiquitin ligases
-
Skaar JR, Pagano M (2009) Control of cell growth by the SCF and APC/C ubiquitin ligases. Curr Opin Cell Biol 21:816-824.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 816-824
-
-
Skaar, J.R.1
Pagano, M.2
-
34
-
-
33750460897
-
Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF (FBX4-alphaB crystallin) complex
-
Lin DI, et al. (2006) Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF (FBX4-alphaB crystallin) complex. Mol Cell 24:355-366.
-
(2006)
Mol Cell
, vol.24
, pp. 355-366
-
-
Lin, D.I.1
-
35
-
-
35548946557
-
Structurally related TPR subunits contribute differently to the function of the anaphase-promoting complex in Drosophila melanogaster
-
Pál M, Nagy O, Ménesi D, Udvardy A, Deák P (2007) Structurally related TPR subunits contribute differently to the function of the anaphase-promoting complex in Drosophila melanogaster. J Cell Sci 120:3238-3248.
-
(2007)
J Cell Sci
, vol.120
, pp. 3238-3248
-
-
Pál, M.1
Nagy, O.2
Ménesi, D.3
Udvardy, A.4
Deák, P.5
-
36
-
-
33745613510
-
Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation
-
Fujii Y, et al. (2006) Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation. Cancer Sci 97:729-736.
-
(2006)
Cancer Sci
, vol.97
, pp. 729-736
-
-
Fujii, Y.1
-
37
-
-
0030888581
-
CCAAT/enhancer-binding protein-delta (C/EBP-delta) is induced in growth- Arrested mouse mammary epithelial cells
-
DOI 10.1074/jbc.272.10.6291
-
O'Rourke J, Yuan R, DeWille J (1997) CCAAT/enhancer-binding protein-delta (C/EBPdelta) is induced in growth-arrested mouse mammary epithelial cells. J Biol Chem 272: 6291-6296. (Pubitemid 27118102)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.10
, pp. 6291-6296
-
-
O'Rourke, J.1
Yuan, R.2
Dewille, J.3
-
38
-
-
0031438080
-
CCAAT/enhancer-binding protein delta activates insulin-like growth factor- I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone
-
DOI 10.1074/jbc.272.50.31793
-
Umayahara Y, Ji C, Centrella M, Rotwein P, McCarthy TL (1997) CCAAT/enhancer-binding protein delta activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone. J Biol Chem 272:31793-31800. (Pubitemid 28013330)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.50
, pp. 31793-31800
-
-
Umayahara, Y.1
Ji, C.2
Centrella, M.3
Rotwein, P.4
McCarthy, T.L.5
-
39
-
-
34250763743
-
C/EBPdelta regulates cell cycle and self-renewal of human limbal stem cells
-
DOI 10.1083/jcb.200703003
-
Barbaro V, et al. (2007) C/EBPdelta regulates cell cycle and self-renewal of human limbal stem cells. J Cell Biol 177:1037-1049. (Pubitemid 46955708)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.6
, pp. 1037-1049
-
-
Barbaro, V.1
Testa, A.2
Di Iorio, E.3
Mavilio, F.4
Pellegrini, G.5
De Luca, M.6
-
40
-
-
67649352637
-
Nuclear cyclin D1 An oncogenic driver in human cancer
-
Kim JK, Diehl JA (2009) Nuclear cyclin D1: An oncogenic driver in human cancer. J Cell Physiol 220:292-296.
-
(2009)
J Cell Physiol
, vol.220
, pp. 292-296
-
-
Kim, J.K.1
Diehl, J.A.2
-
41
-
-
35648964224
-
Cyclin degradation for cancer therapy and chemo-prevention
-
Freemantle SJ, et al. (2007) Cyclin degradation for cancer therapy and chemo-prevention. J Cell Biochem 102:869-877.
-
(2007)
J Cell Biochem
, vol.102
, pp. 869-877
-
-
Freemantle, S.J.1
-
42
-
-
39049107744
-
GSK-3beta regulates cyclin D1 expression: A new target for chemotherapy
-
DOI 10.1016/j.cellsig.2007.10.018, PII S089865680700321X
-
Takahashi-Yanaga F, Sasaguri T (2008) GSK-3beta regulates cyclin D1 expression: A new target for chemotherapy. Cell Signal 20:581-589. (Pubitemid 351241128)
-
(2008)
Cellular Signalling
, vol.20
, Issue.4
, pp. 581-589
-
-
Takahashi-Yanaga, F.1
Sasaguri, T.2
|