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Volumn 111, Issue 3, 2008, Pages 1448-1455

LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G1; LATENT MEMBRANE PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 38949216060     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-10-117655     Document Type: Article
Times cited : (93)

References (31)
  • 1
    • 0035496101 scopus 로고    scopus 로고
    • Epstein-Barr virus: Exploiting the immune system
    • Thorley-Lawson DA. Epstein-Barr virus: exploiting the immune system. Nat Rev Immunol. 2001;1:75-82.
    • (2001) Nat Rev Immunol , vol.1 , pp. 75-82
    • Thorley-Lawson, D.A.1
  • 2
    • 0037209628 scopus 로고    scopus 로고
    • CD40 and its viral mimic, LMP1: Similar means to different ends
    • Lam N, Sugden B. CD40 and its viral mimic, LMP1: similar means to different ends. Cell Signal. 2003;15:9-16.
    • (2003) Cell Signal , vol.15 , pp. 9-16
    • Lam, N.1    Sugden, B.2
  • 3
    • 0028447437 scopus 로고
    • The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
    • Kawabe T, Naka T, Yoshida K, et al. The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity. 1994;1:167-178.
    • (1994) Immunity , vol.1 , pp. 167-178
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3
  • 4
    • 0028486131 scopus 로고
    • Mice deficient for the CD40 ligand
    • Xu J, Foy TM, Laman JD, et al. Mice deficient for the CD40 ligand. Immunity. 1994;1:423-431.
    • (1994) Immunity , vol.1 , pp. 423-431
    • Xu, J.1    Foy, T.M.2    Laman, J.D.3
  • 5
    • 0026427043 scopus 로고
    • Growing human B lymphocytes in the CD40 system
    • Banchereau J, Rousset F. Growing human B lymphocytes in the CD40 system. Nature. 1991;353:678-679.
    • (1991) Nature , vol.353 , pp. 678-679
    • Banchereau, J.1    Rousset, F.2
  • 6
    • 0030465535 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival
    • Zimber-Strobl U, Kempkes B, Marschall G, et al. Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival. EMBO J. 1996;15:7070-7078.
    • (1996) EMBO J , vol.15 , pp. 7070-7078
    • Zimber-Strobl, U.1    Kempkes, B.2    Marschall, G.3
  • 7
    • 10544243364 scopus 로고    scopus 로고
    • Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region
    • Ishida T, Mizushima S, Azuma S, et al. Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J Biol Chem. 1996;271:28745-28748.
    • (1996) J Biol Chem , vol.271 , pp. 28745-28748
    • Ishida, T.1    Mizushima, S.2    Azuma, S.3
  • 8
    • 0032750932 scopus 로고    scopus 로고
    • The residues between the two transformation effector sites of Epstein-Barr virus latent membrane protein 1 are not critical for Blymphocyte growth transformation
    • Izumi KM, Cahir McFarland ED, Riley EA, Rizzo D, Chen Y, Kieff E. The residues between the two transformation effector sites of Epstein-Barr virus latent membrane protein 1 are not critical for Blymphocyte growth transformation. J Virol. 1999;73:9908-9916.
    • (1999) J Virol , vol.73 , pp. 9908-9916
    • Izumi, K.M.1    Cahir McFarland, E.D.2    Riley, E.A.3    Rizzo, D.4    Chen, Y.5    Kieff, E.6
  • 9
    • 0033522511 scopus 로고    scopus 로고
    • LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2
    • Kieser A, Kaiser C, Hammerschmidt W. LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2. EMBO J. 1999;18:2511-2521.
    • (1999) EMBO J , vol.18 , pp. 2511-2521
    • Kieser, A.1    Kaiser, C.2    Hammerschmidt, W.3
  • 10
    • 0030728946 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade
    • Kieser A, Kilger E, Gires O, Ueffing M, Kolch W, Hammerschmidt W. Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade. EMBO J. 1997;16:6478-6485.
    • (1997) EMBO J , vol.16 , pp. 6478-6485
    • Kieser, A.1    Kilger, E.2    Gires, O.3    Ueffing, M.4    Kolch, W.5    Hammerschmidt, W.6
  • 11
    • 0035887040 scopus 로고    scopus 로고
    • TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1
    • Schultheiss U, Puschner S, Kremmer E, et al. TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1. EMBO J. 2001;20:5678-5691.
    • (2001) EMBO J , vol.20 , pp. 5678-5691
    • Schultheiss, U.1    Puschner, S.2    Kremmer, E.3
  • 12
    • 0032788548 scopus 로고    scopus 로고
    • The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation
    • Izumi KM, Cahir McFarland ED, Ting AT, Riley EA, Seed B, Kieff ED. The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation. Mol Cell Biol. 1999;19:5759-5767.
    • (1999) Mol Cell Biol , vol.19 , pp. 5759-5767
    • Izumi, K.M.1    Cahir McFarland, E.D.2    Ting, A.T.3    Riley, E.A.4    Seed, B.5    Kieff, E.D.6
  • 13
    • 0030716307 scopus 로고    scopus 로고
    • Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule
    • Gires O, Zimber-Strobl U, Gonnella R, et al. Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule. EMBO J. 1997;16:6131-6140.
    • (1997) EMBO J , vol.16 , pp. 6131-6140
    • Gires, O.1    Zimber-Strobl, U.2    Gonnella, R.3
  • 14
    • 0033536591 scopus 로고    scopus 로고
    • Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses
    • Uchida J, Yasui T, Takaoka-Shichijo Y, et al. Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses. Science. 1999;286:300-303.
    • (1999) Science , vol.286 , pp. 300-303
    • Uchida, J.1    Yasui, T.2    Takaoka-Shichijo, Y.3
  • 15
    • 8644232546 scopus 로고    scopus 로고
    • Comparative analysis of signal transduction by CD40 and the Epstein-Barr virus oncoprotein LMP1 in vivo
    • Panagopoulos D, Victoratos P, Alexiou M, Kollias G, Mosialos G. Comparative analysis of signal transduction by CD40 and the Epstein-Barr virus oncoprotein LMP1 in vivo. J Virol. 2004;78:13253-13261.
    • (2004) J Virol , vol.78 , pp. 13253-13261
    • Panagopoulos, D.1    Victoratos, P.2    Alexiou, M.3    Kollias, G.4    Mosialos, G.5
  • 16
    • 0030818183 scopus 로고    scopus 로고
    • B lymphocyte-specific, Cre-mediated mutagenesis in mice
    • Rickert RC, Roes J, Rajewsky K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 1997;25:1317-1318.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1317-1318
    • Rickert, R.C.1    Roes, J.2    Rajewsky, K.3
  • 17
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999;21:70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 18
    • 0026638820 scopus 로고
    • Targeted oncogene activation by site-specific recombination in transgenic mice
    • Lakso M, Sauer B, Mosinger B Jr, et al. Targeted oncogene activation by site-specific recombination in transgenic mice. Proc Natl Acad Sci U S A. 1992;89:6232-6236.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 6232-6236
    • Lakso, M.1    Sauer, B.2    Mosinger Jr, B.3
  • 19
    • 0030845386 scopus 로고    scopus 로고
    • Rapid methods for the analysis of immunoglobulin gene hypermutation: Application to transgenic and gene targeted mice
    • Jolly CJ, Klix N, Neuberger MS. Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice. Nucleic Acids Res. 1997;25:1913-1919.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1913-1919
    • Jolly, C.J.1    Klix, N.2    Neuberger, M.S.3
  • 20
    • 0242495542 scopus 로고    scopus 로고
    • EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching
    • He B, Raab-Traub N, Casali P, Cerutti A. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J Immunol. 2003;171:5215-5224.
    • (2003) J Immunol , vol.171 , pp. 5215-5224
    • He, B.1    Raab-Traub, N.2    Casali, P.3    Cerutti, A.4
  • 21
    • 4143124227 scopus 로고    scopus 로고
    • Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture
    • Stunz LL, Busch LK, Munroe ME, et al. Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. Immunity. 2004;21:255-266.
    • (2004) Immunity , vol.21 , pp. 255-266
    • Stunz, L.L.1    Busch, L.K.2    Munroe, M.E.3
  • 22
    • 0035230221 scopus 로고    scopus 로고
    • Bipotential B-macrophage progenitors are present in adult bone marrow
    • Montecino-Rodriguez E, Leathers H, Dorshkind K. Bipotential B-macrophage progenitors are present in adult bone marrow. Nat Immunol. 2001;2:83-88.
    • (2001) Nat Immunol , vol.2 , pp. 83-88
    • Montecino-Rodriguez, E.1    Leathers, H.2    Dorshkind, K.3
  • 23
    • 4043092238 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
    • Munn DH, Sharma MD, Hou D, et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest. 2004;114:280-290.
    • (2004) J Clin Invest , vol.114 , pp. 280-290
    • Munn, D.H.1    Sharma, M.D.2    Hou, D.3
  • 24
    • 0030221688 scopus 로고    scopus 로고
    • Promotion of IL8, IL10, TNF alpha and TNF beta production by EBV infection
    • Klein SC, Kube D, Abts H, Diehl V, Tesch H. Promotion of IL8, IL10, TNF alpha and TNF beta production by EBV infection. Leuk Res. 1996;20:633-636.
    • (1996) Leuk Res , vol.20 , pp. 633-636
    • Klein, S.C.1    Kube, D.2    Abts, H.3    Diehl, V.4    Tesch, H.5
  • 25
    • 0011444474 scopus 로고
    • Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constantregion genes
    • Stavnezer J, Radcliffe G, Lin YC, et al. Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constantregion genes. Proc Natl Acad Sci U S A. 1988;85:7704-7708.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 7704-7708
    • Stavnezer, J.1    Radcliffe, G.2    Lin, Y.C.3
  • 26
    • 0031859134 scopus 로고    scopus 로고
    • STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination
    • Linehan LA, Warren WD, Thompson PA, Grusby MJ, Berton MT. STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. J Immunol. 1998;161:302-310.
    • (1998) J Immunol , vol.161 , pp. 302-310
    • Linehan, L.A.1    Warren, W.D.2    Thompson, P.A.3    Grusby, M.J.4    Berton, M.T.5
  • 27
    • 0033153426 scopus 로고    scopus 로고
    • Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins
    • Gires O, Kohlhuber F, Kilger E, et al. Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins. EMBO J. 1999;18:3064-3073.
    • (1999) EMBO J , vol.18 , pp. 3064-3073
    • Gires, O.1    Kohlhuber, F.2    Kilger, E.3
  • 29
    • 0033696976 scopus 로고    scopus 로고
    • The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell
    • Babcock GJ, Hochberg D, Thorley-Lawson AD. The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell. Immunity. 2000;13:497-506.
    • (2000) Immunity , vol.13 , pp. 497-506
    • Babcock, G.J.1    Hochberg, D.2    Thorley-Lawson, A.D.3
  • 30
    • 0033680735 scopus 로고    scopus 로고
    • EBV-infected B cells in infectious mononucleosis: Viral strategies for spreading in the B cell compartment and establishing latency
    • Kurth J, Spieker T, Wustrow J, et al. EBV-infected B cells in infectious mononucleosis: viral strategies for spreading in the B cell compartment and establishing latency. Immunity. 2000;13:485-495.
    • (2000) Immunity , vol.13 , pp. 485-495
    • Kurth, J.1    Spieker, T.2    Wustrow, J.3
  • 31
    • 34247392757 scopus 로고    scopus 로고
    • IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta
    • Waisman A, Kraus M, Seagal J, et al. IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta. J Exp Med. 2007;204:747-758.
    • (2007) J Exp Med , vol.204 , pp. 747-758
    • Waisman, A.1    Kraus, M.2    Seagal, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.