Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection

Journal of Experimental Medicine

Volumn 209, Issue 1, 2012, Pages 77-91

  Wang, Chao ^a   McPherson, Ann J ^a   Jones, R Brad ^a   Kawamura, Kim S ^d   Lin, Gloria H Y ^a   Lang, Philipp A ^a,d   Ambagala, Thanuja ^a   Pellegrini, Marc ^d,j   Calzascia, Thomas ^d,k   Aidarus, Nasra ^a   Elford, Alisha R ^d   Yue, Feng Yun ^b   Kremmer, Elisabeth ^e   Kovacs, Colin M ^f   Benko, Erika ^f   Tremblay, Cecile ^g   Routy, Jean Pierre ^h   Bernard, Nicole F ⁱ   Ostrowski, Mario A ^a,b,c   Ohashi, Pamela S ^a,d   Watts, Tania H ^a   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

^f MAPLE LEAF MEDICAL CLINIC   (Canada)

^g UNIVERSITÉ DE MONTRÉAL   (Canada)

^h ROYAL VICTORIA HOSPITAL   (Canada)

ⁱ RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^j WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^k NOVARTIS PHARMA AG   (Switzerland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 17; PROGRAMMED DEATH 1 LIGAND 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESENSITIZATION; EX VIVO STUDY; FLOW CYTOMETRY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOREGULATION; INFECTION CONTROL; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; T LYMPHOCYTE SUBPOPULATION; UPREGULATION; VIRUS LOAD;

4-1BB LIGAND; ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES; CD8-POSITIVE T-LYMPHOCYTES; CHLOROQUINE; CHRONIC DISEASE; DOWN-REGULATION; GENE EXPRESSION; HIV INFECTIONS; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-7; LYMPHOCYTIC CHORIOMENINGITIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROGRAMMED CELL DEATH 1 RECEPTOR; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; VIRAL LOAD;

EID: 84863116516     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110675     Document Type: Article

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