-
1
-
-
33644955272
-
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
-
Anstee, Q.M. & Goldin, R.D. (2006) Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int. J. Exp. Pathol. 87, 1-16.
-
(2006)
Int. J. Exp. Pathol.
, vol.87
, pp. 1-16
-
-
Anstee, Q.M.1
Goldin, R.D.2
-
2
-
-
84858216481
-
Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function
-
Beigi, F., Gonzalez, D.R., Minhas, K.M., Sun, Q.A., Foster, M.W., Khan, S.A., Treuer, A.V., Dulce, R.A., Harrison, R.W., Saraiva, R.M., Premer, C., Schulman, I.H., Stamler, J.S. & Hare, J.M. (2012) Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function. Proc. Natl Acad. Sci. USA 109, 4314-4319.
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 4314-4319
-
-
Beigi, F.1
Gonzalez, D.R.2
Minhas, K.M.3
Sun, Q.A.4
Foster, M.W.5
Khan, S.A.6
Treuer, A.V.7
Dulce, R.A.8
Harrison, R.W.9
Saraiva, R.M.10
Premer, C.11
Schulman, I.H.12
Stamler, J.S.13
Hare, J.M.14
-
3
-
-
41849123475
-
Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment
-
Carter-Kent, C., Zein, N.N. & Feldstein, A.E. (2008) Cytokines in the pathogenesis of fatty liver and disease progression to steatohepatitis: implications for treatment. Am. J. Gastroenterol. 103, 1036-1042.
-
(2008)
Am. J. Gastroenterol.
, vol.103
, pp. 1036-1042
-
-
Carter-Kent, C.1
Zein, N.N.2
Feldstein, A.E.3
-
4
-
-
72649103895
-
Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis
-
Chowdhry, S., Nazmy, M.H., Meakin, P.J., Dinkova-Kostova, A.T., Walsh, S.V., Tsujita, T., Dillon, J.F., Ashford, M.L.J. & Hayes, J.D. (2010) Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis. Free Radic. Biol. Med. 48, 357-371.
-
(2010)
Free Radic. Biol. Med.
, vol.48
, pp. 357-371
-
-
Chowdhry, S.1
Nazmy, M.H.2
Meakin, P.J.3
Dinkova-Kostova, A.T.4
Walsh, S.V.5
Tsujita, T.6
Dillon, J.F.7
Ashford, M.L.J.8
Hayes, J.D.9
-
5
-
-
84892496207
-
S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury
-
Cox, A.G., Saunders, D.C., Kelsey, P.B. Jr, Conway, A.A., Tesmenitsky, Y., Marchini, J.F., Brown, K.K., Stamler, J.S., Colagiovanni, D.B., Rosenthal, G.J., Croce, K.J., North, T.E. & Goessling, W. (2014) S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury. Cell Rep. 6, 56-69.
-
(2014)
Cell Rep.
, vol.6
, pp. 56-69
-
-
Cox, A.G.1
Saunders, D.C.2
Kelsey Jr, P.B.3
Conway, A.A.4
Tesmenitsky, Y.5
Marchini, J.F.6
Brown, K.K.7
Stamler, J.S.8
Colagiovanni, D.B.9
Rosenthal, G.J.10
Croce, K.J.11
North, T.E.12
Goessling, W.13
-
6
-
-
0033546155
-
Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid
-
Deltour, L., Foglio, M.H. & Duester, G. (1999) Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid. J. Biol. Chem. 274, 16796-16801.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16796-16801
-
-
Deltour, L.1
Foglio, M.H.2
Duester, G.3
-
7
-
-
84859570178
-
Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition
-
Foster, M.W., Yang, Z., Gooden, D.M., Thompson, J.W., Ball, C.H., Turner, M.E., Hou, Y., Pi, J., Moseley, M.A. & Que, L.G. (2012) Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition. J. Proteome Res. 11, 2480-2491.
-
(2012)
J. Proteome Res.
, vol.11
, pp. 2480-2491
-
-
Foster, M.W.1
Yang, Z.2
Gooden, D.M.3
Thompson, J.W.4
Ball, C.H.5
Turner, M.E.6
Hou, Y.7
Pi, J.8
Moseley, M.A.9
Que, L.G.10
-
8
-
-
84908239975
-
Characterizing genetic variation of adrenergic signalling pathways in Takotsubo (stress) cardiomyopathy exomes
-
Goodloe, A.H., Evans, J.M., Middha, S., Prasad, A. & Olson, T.M. (2014) Characterizing genetic variation of adrenergic signalling pathways in Takotsubo (stress) cardiomyopathy exomes. Eur. J. Heart Fail. 16, 942-949.
-
(2014)
Eur. J. Heart Fail.
, vol.16
, pp. 942-949
-
-
Goodloe, A.H.1
Evans, J.M.2
Middha, S.3
Prasad, A.4
Olson, T.M.5
-
9
-
-
84863237651
-
Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase
-
Green, L.S., Chun, L.E., Patton, A.K., Sun, X., Rosenthal, G.J. & Richards, J.P. (2012) Mechanism of inhibition for N6022, a first-in-class drug targeting S-nitrosoglutathione reductase. Biochemistry 51, 2157-2168.
-
(2012)
Biochemistry
, vol.51
, pp. 2157-2168
-
-
Green, L.S.1
Chun, L.E.2
Patton, A.K.3
Sun, X.4
Rosenthal, G.J.5
Richards, J.P.6
-
10
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., Yamamoto, M. & Nabeshima, Y. (1997) An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236, 313-322.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
11
-
-
27644581598
-
Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans
-
Kohlmeier, M., de Costa, K.A., Fischer, L.M. & Zeisel, S.H. (2005) Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc. Natl Acad. Sci. USA 102, 16025-16030.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 16025-16030
-
-
Kohlmeier, M.1
de Costa, K.A.2
Fischer, L.M.3
Zeisel, S.H.4
-
12
-
-
33646121972
-
The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis
-
Li, Z., Agellon, L.B., Allen, T.M., Umeda, M., Jewell, L., Mason, A. & Vance, D.E. (2006) The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metab. 3, 321-331.
-
(2006)
Cell Metab.
, vol.3
, pp. 321-331
-
-
Li, Z.1
Agellon, L.B.2
Allen, T.M.3
Umeda, M.4
Jewell, L.5
Mason, A.6
Vance, D.E.7
-
13
-
-
0035932413
-
A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans
-
Liu, L., Hausladen, A., Zeng, M., Que, L., Heitman, J. & Stamler, J.S. (2001) A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature 410, 490-494.
-
(2001)
Nature
, vol.410
, pp. 490-494
-
-
Liu, L.1
Hausladen, A.2
Zeng, M.3
Que, L.4
Heitman, J.5
Stamler, J.S.6
-
14
-
-
10744230465
-
Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock
-
Liu, L., Yan, Y., Zeng, M., Zhang, J., Hanes, M.A., Ahearn, G., McMahon, T.J., Dickfeld, T., Marshall, H.E., Que, L.G. & Stamler, J.S. (2004) Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell 116, 617-628.
-
(2004)
Cell
, vol.116
, pp. 617-628
-
-
Liu, L.1
Yan, Y.2
Zeng, M.3
Zhang, J.4
Hanes, M.A.5
Ahearn, G.6
McMahon, T.J.7
Dickfeld, T.8
Marshall, H.E.9
Que, L.G.10
Stamler, J.S.11
-
15
-
-
0037382786
-
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
-
Marchesini, G., Bugianesi, E., Forlani, G., Cerrelli, F., Lenzi, M., Manini, R., Natale, S., Vanni, E., Villanova, N., Melchionda, N. & Rizzetto, M. (2003) Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 37, 917-923.
-
(2003)
Hepatology
, vol.37
, pp. 917-923
-
-
Marchesini, G.1
Bugianesi, E.2
Forlani, G.3
Cerrelli, F.4
Lenzi, M.5
Manini, R.6
Natale, S.7
Vanni, E.8
Villanova, N.9
Melchionda, N.10
Rizzetto, M.11
-
16
-
-
48749091560
-
Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements
-
Maruyama, A., Tsukamoto, S., Nishikawa, K., Yoshida, A., Harada, N., Motojima, K., Ishii, T., Nakane, A., Yamamoto, M. & Itoh, K. (2008) Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements. Arch. Biochem. Biophys. 477, 139-145.
-
(2008)
Arch. Biochem. Biophys.
, vol.477
, pp. 139-145
-
-
Maruyama, A.1
Tsukamoto, S.2
Nishikawa, K.3
Yoshida, A.4
Harada, N.5
Motojima, K.6
Ishii, T.7
Nakane, A.8
Yamamoto, M.9
Itoh, K.10
-
17
-
-
34347392512
-
Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury
-
Marzec, J.M., Christie, J.D., Reddy, S.P., Jedlicka, A.E., Vuong, H., Lanken, P.N., Aplenc, R., Yamamoto, T., Yamamoto, M., Cho, H.Y. & Kleeberger, S.R. (2007) Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. FASEB J. 21, 2237-2246.
-
(2007)
FASEB J.
, vol.21
, pp. 2237-2246
-
-
Marzec, J.M.1
Christie, J.D.2
Reddy, S.P.3
Jedlicka, A.E.4
Vuong, H.5
Lanken, P.N.6
Aplenc, R.7
Yamamoto, T.8
Yamamoto, M.9
Cho, H.Y.10
Kleeberger, S.R.11
-
18
-
-
78650509515
-
Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals
-
McMahon, M., Lamont, D.J., Beattie, K.A. & Hayes, J.D. (2010) Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals. Proc. Natl Acad. Sci. USA 107, 18838-18843.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 18838-18843
-
-
McMahon, M.1
Lamont, D.J.2
Beattie, K.A.3
Hayes, J.D.4
-
19
-
-
78751682729
-
Molecular determinants for small Maf protein control of platelet production
-
Motohashi, H., Fujita, R., Takayama, M., Inoue, A., Katsuoka, F., Bresnick, E.H. & Yamamoto, M. (2011) Molecular determinants for small Maf protein control of platelet production. Mol. Cell. Biol. 31, 151-162.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 151-162
-
-
Motohashi, H.1
Fujita, R.2
Takayama, M.3
Inoue, A.4
Katsuoka, F.5
Bresnick, E.H.6
Yamamoto, M.7
-
20
-
-
2342511435
-
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
-
Motohashi, H., Katsuoka, F., Engel, J.D. & Yamamoto, M. (2004) Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. Proc. Natl Acad. Sci. USA 101, 6379-6384.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 6379-6384
-
-
Motohashi, H.1
Katsuoka, F.2
Engel, J.D.3
Yamamoto, M.4
-
21
-
-
33745030048
-
MafG sumoylation is required for active transcriptional repression
-
Motohashi, H., Katsuoka, F., Miyoshi, C., Uchimura, Y., Saitoh, H., Francastel, C., Engel, J.D. & Yamamoto, M. (2006) MafG sumoylation is required for active transcriptional repression. Mol. Cell. Biol. 26, 4652-4663.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 4652-4663
-
-
Motohashi, H.1
Katsuoka, F.2
Miyoshi, C.3
Uchimura, Y.4
Saitoh, H.5
Francastel, C.6
Engel, J.D.7
Yamamoto, M.8
-
22
-
-
64449087605
-
Homocysteine and lipids: S-adenosyl methionine as a key intermediate
-
Obeid, R. & Herrmann, W. (2009) Homocysteine and lipids: S-adenosyl methionine as a key intermediate. FEBS Lett. 583, 1215-1225.
-
(2009)
FEBS Lett.
, vol.583
, pp. 1215-1225
-
-
Obeid, R.1
Herrmann, W.2
-
23
-
-
28144445947
-
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity
-
Okawa, H., Motohashi, H., Kobayashi, A., Aburatani, H., Kensler, T.W. & Yamamoto, M. (2006) Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. Biochem. Biophys. Res. Commun. 339, 79-88.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, pp. 79-88
-
-
Okawa, H.1
Motohashi, H.2
Kobayashi, A.3
Aburatani, H.4
Kensler, T.W.5
Yamamoto, M.6
-
24
-
-
18244385511
-
Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association
-
Pagano, G., Pacini, G., Musso, G., Gambino, R., Mecca, F., Depetris, N., Cassader, M., David, E., Cavallo-Perin, P. & Rizzetto, M. (2002) Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association. Hepatology 35, 367-372.
-
(2002)
Hepatology
, vol.35
, pp. 367-372
-
-
Pagano, G.1
Pacini, G.2
Musso, G.3
Gambino, R.4
Mecca, F.5
Depetris, N.6
Cassader, M.7
David, E.8
Cavallo-Perin, P.9
Rizzetto, M.10
-
25
-
-
27644441867
-
Effect of oral creatine supplementation on urinary methylamine, formaldehyde, and formate
-
Poortmans, J.R., Kumps, A., Duez, P., Fofonka, A., Carpentier, A. & Francaux, M. (2005) Effect of oral creatine supplementation on urinary methylamine, formaldehyde, and formate. Med. Sci. Sports Exerc. 37, 1717-1720.
-
(2005)
Med. Sci. Sports Exerc.
, vol.37
, pp. 1717-1720
-
-
Poortmans, J.R.1
Kumps, A.2
Duez, P.3
Fofonka, A.4
Carpentier, A.5
Francaux, M.6
-
26
-
-
20444410779
-
Protection from experimental asthma by an endogenous bronchodilator
-
Que, L.G., Liu, L., Yan, Y., Whitehead, G.S., Gavett, S.H., Schwartz, D.A. & Stamler, J.S. (2005) Protection from experimental asthma by an endogenous bronchodilator. Science 308, 1618-1621.
-
(2005)
Science
, vol.308
, pp. 1618-1621
-
-
Que, L.G.1
Liu, L.2
Yan, Y.3
Whitehead, G.S.4
Gavett, S.H.5
Schwartz, D.A.6
Stamler, J.S.7
-
27
-
-
33645828659
-
Lipid metabolism and liver inflammation. II. Fatty liver diseases and fatty acid oxidation
-
Reddy, J.K. & Rao, M.S. (2006) Lipid metabolism and liver inflammation. II. Fatty liver diseases and fatty acid oxidation. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G852-G858.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
, pp. G852-G858
-
-
Reddy, J.K.1
Rao, M.S.2
-
28
-
-
82955235602
-
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway
-
Rosado, I.V., Langevin, F., Crossan, G.P., Takata, M. & Patel, K.J. (2011) Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway. Nat. Struct. Mol. Biol. 18, 1432-1434.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1432-1434
-
-
Rosado, I.V.1
Langevin, F.2
Crossan, G.P.3
Takata, M.4
Patel, K.J.5
-
29
-
-
35348941210
-
Protein S-guanylation by the biological signal 8-nitroguanosine 3',5'-cyclic monophosphate
-
Sawa, T., Zaki, M.H., Okamoto, T., Akuta, T., Tokutomi, Y., Kim-Mitsuyama, S., Ihara, H., Kobayashi, A., Yamamoto, M., Fujii, S., Arimoto, H. & Akaike, T. (2007) Protein S-guanylation by the biological signal 8-nitroguanosine 3', 5'-cyclic monophosphate. Nat. Chem. Biol. 3, 727-735.
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 727-735
-
-
Sawa, T.1
Zaki, M.H.2
Okamoto, T.3
Akuta, T.4
Tokutomi, Y.5
Kim-Mitsuyama, S.6
Ihara, H.7
Kobayashi, A.8
Yamamoto, M.9
Fujii, S.10
Arimoto, H.11
Akaike, T.12
-
30
-
-
84902544544
-
Novel insights on interactions between folate and lipid metabolism
-
da Silva, R.P., Kelly, K.B., Rajabi, A.A. & Jacobs, R.L. (2014) Novel insights on interactions between folate and lipid metabolism. BioFactors 40, 277-283.
-
(2014)
BioFactors
, vol.40
, pp. 277-283
-
-
da Silva, R.P.1
Kelly, K.B.2
Rajabi, A.A.3
Jacobs, R.L.4
-
31
-
-
84878434034
-
Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression
-
Sips, P.Y., Irie, T., Shinozaki, S., Sakai, M., Shimizu, N., Nguyen, R., Stamler, J.S., Chao, W., Kaneki, M. & Ichinose, F. (2013) Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression. Am. J. Physiol. Heart Circ. Physiol. 304, H1134-H1146.
-
(2013)
Am. J. Physiol. Heart Circ. Physiol.
, vol.304
, pp. H1134-H1146
-
-
Sips, P.Y.1
Irie, T.2
Shinozaki, S.3
Sakai, M.4
Shimizu, N.5
Nguyen, R.6
Stamler, J.S.7
Chao, W.8
Kaneki, M.9
Ichinose, F.10
-
32
-
-
0034654337
-
Amino acid analysis by capillary electrophoresis electrospray ionization mass spectrometry
-
Soga, T. & Heiger, D.N. (2000) Amino acid analysis by capillary electrophoresis electrospray ionization mass spectrometry. Anal. Chem. 72, 1236-1241.
-
(2000)
Anal. Chem.
, vol.72
, pp. 1236-1241
-
-
Soga, T.1
Heiger, D.N.2
-
33
-
-
76749149157
-
Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice
-
Sugimoto, H., Okada, K., Shoda, J., Warabi, E., Ishige, K., Ueda, T., Taguchi, K., Yanagawa, T., Nakahara, A., Hyodo, I., Ishii, T. & Yamamoto, M. (2010a) Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 298, 283-294.
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.298
, pp. 283-294
-
-
Sugimoto, H.1
Okada, K.2
Shoda, J.3
Warabi, E.4
Ishige, K.5
Ueda, T.6
Taguchi, K.7
Yanagawa, T.8
Nakahara, A.9
Hyodo, I.10
Ishii, T.11
Yamamoto, M.12
-
34
-
-
77954744279
-
Prediction of metabolite identity from accurate mass, migration time prediction and isotopic pattern information in CE-TOFMS data
-
Sugimoto, M., Hirayama, A., Robert, M., Abe, S., Soga, T. & Tomita, M. (2010b) Prediction of metabolite identity from accurate mass, migration time prediction and isotopic pattern information in CE-TOFMS data. Electrophoresis 31, 2311-2318.
-
(2010)
Electrophoresis
, vol.31
, pp. 2311-2318
-
-
Sugimoto, M.1
Hirayama, A.2
Robert, M.3
Abe, S.4
Soga, T.5
Tomita, M.6
-
35
-
-
77949297718
-
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles
-
Sugimoto, M., Wong, D.T., Hirayama, A., Soga, T. & Tomita, M. (2010c) Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics 6, 78-95.
-
(2010)
Metabolomics
, vol.6
, pp. 78-95
-
-
Sugimoto, M.1
Wong, D.T.2
Hirayama, A.3
Soga, T.4
Tomita, M.5
-
36
-
-
84878620505
-
Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels
-
Suzuki, T., Shibata, T., Takaya, K., Shiraishi, K., Kohno, T., Kunitoh, H., Tsuta, K., Furuta, K., Goto, K., Hosoda, F., Sakamoto, H., Motohashi, H. & Yamamoto, M. (2013) Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels. Mol. Cell. Biol. 33, 2402-2412.
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 2402-2412
-
-
Suzuki, T.1
Shibata, T.2
Takaya, K.3
Shiraishi, K.4
Kohno, T.5
Kunitoh, H.6
Tsuta, K.7
Furuta, K.8
Goto, K.9
Hosoda, F.10
Sakamoto, H.11
Motohashi, H.12
Yamamoto, M.13
-
37
-
-
77953460849
-
Genetic analysis of cytoprotective functions supported by graded expression of Keap1
-
Taguchi, K., Maher, J.M., Suzuki, T., Kawatani, Y., Motohashi, H. & Yamamoto, M. (2010) Genetic analysis of cytoprotective functions supported by graded expression of Keap1. Mol. Cell. Biol. 30, 3016-3026.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 3016-3026
-
-
Taguchi, K.1
Maher, J.M.2
Suzuki, T.3
Kawatani, Y.4
Motohashi, H.5
Yamamoto, M.6
-
38
-
-
84889658736
-
Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice
-
Tang, C.H., Seeley, E.J., Huang, X., Wolters, P.J. & Liu, L. (2013a) Increased susceptibility to Klebsiella pneumonia and mortality in GSNOR-deficient mice. Biochem. Biophys. Res. Commun. 442, 122-126.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.442
, pp. 122-126
-
-
Tang, C.H.1
Seeley, E.J.2
Huang, X.3
Wolters, P.J.4
Liu, L.5
-
39
-
-
84877739715
-
Hepatocarcinogenesis driven by GSNOR deficiency is prevented by iNOS inhibition
-
Tang, C.H., Wei, W., Hanes, M.A. & Liu, L. (2013b) Hepatocarcinogenesis driven by GSNOR deficiency is prevented by iNOS inhibition. Cancer Res. 73, 2897-2904.
-
(2013)
Cancer Res.
, vol.73
, pp. 2897-2904
-
-
Tang, C.H.1
Wei, W.2
Hanes, M.A.3
Liu, L.4
-
40
-
-
80051545287
-
The Keap1-Nrf2 system as an in vivo sensor for electrophiles
-
Uruno, A. & Motohashi, H. (2011) The Keap1-Nrf2 system as an in vivo sensor for electrophiles. Nitric Oxide 25, 153-160.
-
(2011)
Nitric Oxide
, vol.25
, pp. 153-160
-
-
Uruno, A.1
Motohashi, H.2
-
41
-
-
43249108174
-
Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis
-
Vance, D.E. (2008) Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis. Curr. Opin. Lipidol. 19, 229-234.
-
(2008)
Curr. Opin. Lipidol.
, vol.19
, pp. 229-234
-
-
Vance, D.E.1
-
42
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi, N., Itoh, K., Wakabayashi, J., Motohashi, H., Noda, S., Takahashi, S., Imakado, S., Kotsuji, T., Otsuka, F., Roop, D.R., Harada, T., Engel, J.D. & Yamamoto, M. (2003) Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat. Genet. 35, 238-245.
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otsuka, F.9
Roop, D.R.10
Harada, T.11
Engel, J.D.12
Yamamoto, M.13
-
43
-
-
77952963414
-
S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis
-
19ra13
-
Wei, W., Li, B., Hanes, M.A., Kakar, S., Chen, X. & Liu, L. (2010) S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis. Sci. Transl. Med. 2, 19ra13.
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Wei, W.1
Li, B.2
Hanes, M.A.3
Kakar, S.4
Chen, X.5
Liu, L.6
-
44
-
-
79960030755
-
Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine
-
Wei, W., Yang, Z., Tang, C.H. & Liu, L. (2011) Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. Carcinogenesis 32, 973-977.
-
(2011)
Carcinogenesis
, vol.32
, pp. 973-977
-
-
Wei, W.1
Yang, Z.2
Tang, C.H.3
Liu, L.4
-
45
-
-
0023833533
-
The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes
-
Yao, Z. & Vance, S.E. (1988) The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes. J. Biol. Chem. 263, 2998-3004.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 2998-3004
-
-
Yao, Z.1
Vance, S.E.2
-
46
-
-
84906498641
-
Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice
-
Yi, H.S., Lee, Y.S., Byun, J.S., Seo, W., Jeong, J.M., Park, O., Duester, G., Haseba, T., Kim, S.C., Park, K.G., Gao, B. & Jeong, W.I. (2014) Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice. Hepatology 60, 1044-1053.
-
(2014)
Hepatology
, vol.60
, pp. 1044-1053
-
-
Yi, H.S.1
Lee, Y.S.2
Byun, J.S.3
Seo, W.4
Jeong, J.M.5
Park, O.6
Duester, G.7
Haseba, T.8
Kim, S.C.9
Park, K.G.10
Gao, B.11
Jeong, W.I.12
-
47
-
-
77952952816
-
Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet
-
Zhang, Y.-K.J., Yeager, R.L., Tanaka, Y. & Klaassen, C.D. (2010) Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet. Toxicol. Appl. Pharmacol. 245, 326-334.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.245
, pp. 326-334
-
-
Zhang, Y.-K.1
Yeager, R.L.2
Tanaka, Y.3
Klaassen, C.D.4
|