Molecular determinants for small maf protein control of platelet production

Molecular and Cellular Biology

Volumn 31, Issue 1, 2011, Pages 151-162

  Motohashi, Hozumi ^a   Fujita, Rie ^a   Takayama, Mariko ^a   Inoue, Ai ^a   Katsuoka, Fumiki ^a   Bresnick, Emery H ^b   Yamamoto, Masayuki ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR MAF; TRANSCRIPTION FACTOR NF E2 P45 SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASIC LEUCINE ZIPPER MOTIF; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS MATRIX; CONTROLLED STUDY; HISTOPATHOLOGY; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; SPLENOMEGALY; THROMBOCYTE ACTIVATION; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; BLOOD PLATELETS; CELL LINE; CONSERVED SEQUENCE; DNA PRIMERS; HUMANS; MAF TRANSCRIPTION FACTORS, SMALL; MAFG TRANSCRIPTION FACTOR; MEGAKARYOCYTES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; THROMBOPOIESIS; TRANSCRIPTIONAL ACTIVATION;

MUS; MUS MUSCULUS;

EID: 78751682729     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00798-10     Document Type: Article

References (52)

1. Blencowe, B. J., J. A. Nickerson, R. Issner, S. Penman, and P. A. Sharp. 1994. Association of nuclear matrix antigens with exon-containing splicing complex. J. Cell Biol. 127:593-607.
2. Chen, Z., M. Hu, and R. A. Shivdasani. 2007. Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stagespecific molecular markers and a novel transcriptional target of NF-E2. Blood 109:1451-1459.
3. Choi, J.-Y., J. Pratap, A. Javed, S. K. Zaidi, L. Xing, E. Balint, S. Dalamangas, B. Boyce, A. J. van Wijnen, J. B. Lian, J. L. Stein, S. N. Jones, and G. S. Stein. 2001. Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development. Proc. Natl. Acad. Sci. U. S. A. 98:8650-8655.
4. Dahmcke, C. M., S. Buchmann-Moller, N. A. Jensen, and C. Mitchelmore. 2008. Altered splicing in exon 8 of the DNA replication factor CIZ1 affects subnuclear distribution and is associated with Alzheimer's disease. Mol. Cell. Neurosci. 38:589-594.
5. Demers, C., C.-P. Chaturvedi, J. A. Ranishi, G. Juban, P. Lai, F. Morle, R. Aebersold, F. J. Dilworth, M. Groudine, and M. Brand. 2007. Activatormediated recruitment of the MLL2 methyltransferase complex to the β-globinlocus. Mol. Cell 27:573-584.
6. Deveaux, S., S. Cohen-Kaminsky, R. A. Shivdasani, N. C. Andrews, A. Filipe, I. Kuzniak, S. H. Orkin, P. H. Roméo, and V. Mignotte. 1997. p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes. EMBO J. 16:5654-5661.
7. Fey, E. G., K. M. Wan, and S. Penman. 1984. Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three dimensional organization and protein composition. J. Cell Biol. 98:1973-1984.
8. Francastel, C., D. Schubeler, D. I. Martin, and M. Groudine. 2000. Nuclear compartmentalization and gene activity. Nat. Rev. Mol. Cell Biol. 1:137-143.
9. Francastel, C., W. Magis, and M. Groudine. 2001. Nuclear relocation of a transactivator subunit precedes target gene activation. Proc. Natl. Acad. Sci. U. S. A. 98:12120-12125.
10. Grandori, C., S. M. Cowley, L. P. James, and R. N. Eisenman. 2000. The Myc/Max/Mad network and the transcriptional control of cell behavior. Annu. Rev. Cell Dev. Biol. 16:653-699.
11. Hecker, C.-M., M. Rabiller, K. Haglund, P. Bayer, and I. Dikic. 2006. Specification of SUMO1- and SUMO2-interacting motifs. J. Biol. Chem. 281:16117-16127.
12. Holaska, J. M., and K. L. Wilson. 2007. An emerin "proteome": purification of distinct emerin-containing complex from Hela cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechano-sensing and nuclear architecture. Biochemistry 46:8897-8908.
13. Hu, Q., Y.-S. Kwon, E. Nunez, M. D. Cardamone, K. R. Hutt, K. A. Ohgi, I. Garcia-Bassets, D. W. Rose, C. K. Glass, M. G. Rosenfeld, and X.-D. Fu. 2008. Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc. Natl. Acad. Sci. U. S. A. 105:19199-19204.
14. Igarashi, K., K. Kataoka, K. Itoh, N. Hayashi, M. Nishizawa, and M. Yamamoto. 1994. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367:568-572. (Pubitemid 24055517)
15. Ishii, T., K. Itoh, S. Takahashi, H. Sato, T. Yanagawa, Y. Katoh, S. Bannai, and M. Yamamoto. 2000. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J. Biol. Chem. 275:16023-16029.
16. Itoh, K., T. Chiba, S. Takahashi, T. Ishii, K. Igarashi, Y. Katoh, T. Oyake, N. Hayashi, K. Satoh, I. Hatayama, M. Yamamoto, and Y. Nabeshima. 1997. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236:313-322.
17. Jackson, P. K. 2001. A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Genes Dev. 15:3053-3058.
18. Katsuoka, F., H. Motohashi, Y. Tamagawa, S. Kure, K. Igarashi, J. D. Engel, and M. Yamamoto. 2003. Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response. Mol. Cell. Biol. 23:1163-1174.
19. Katsuoka, F., H. Motohashi, T. Ishii, H. Aburatani, J. D. Engel, and M. Yamamoto. 2005. Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes. Mol. Cell. Biol. 25:8044-8051.
20. Kiekhaefer, C. M., J. A. Grass, K. D. Johnson, M. E. Boyer, and E. H. Bresnick. 2002. Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain. Proc. Natl. Acad. Sci. U. S. A. 99:14309-14314.
21. Kimura, M., T. Yamamoto, J. Zhang, K. Itoh, M. Kyo, T. Kamiya, H. Aburatani, F. Katsuoka, H. Kurokawa, T. Tanaka, H. Motohashi, and M. Yamamoto. 2007. Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer. J. Biol. Chem. 282:33681-33690.
22. Kliewer, S. A., K. Umesono, D. J. Mangelsdorf, and R. M. Evans. 1992. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signaling. Nature 355:446-449.
23. Kyo, M., T. Yamamoto, H. Motohashi, T. Kamiya, T. Kuroita, T. Tanaka, J. D. Engel, B. Kawakami, and M. Yamamoto. 2004. Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique. Genes Cells 9:153-164.
24. Lecine, P., J.-L. Villeval, P. Vyas, B. Swencki, Y. Xu, and R. A. Shivdasani. 1998. Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes. Blood 92:1608-1616.
25. Levin, J., J.-P. Peng, G. R. Baker, J.-L. Villeval, P. Lecine, S. A. Burstein, and R. A. Shivdasani. 1999. Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2. Blood 94:3037-3047.
26. Massari, M. E., and C. Murre. 2000. Helix-loop-helix proteins: regulators of transcription in eukaryotic organisms. Mol. Cell. Biol. 20:429-440.
27. Misteli, T. 2007. Beyond the sequence: cellular organization of genome function. Cell 128:787-800. (Pubitemid 46273571)
28. Mosser, E. A., J. D. Kasanov, E. C. Forsberg, B. K. Kay, P. A. Ney, and E. H. Bresnick. 1998. Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domains. Biochemistry 37:13686-13695.
29. Motohashi, H., K. Igarashi, K. Onodera, S. Takahashi, H. Ohtani, M. Nakafuku, M. Nishizawa, J. D. Engel, and M. Yamamoto. 1996. Mesodermal-vs. neuronal-specific expression of MafK is elicited by different promoters. Genes Cells 1:223-238.
30. Motohashi, H., F. Katsuoka, J. A. Shavit, J. D. Engel, and M. Yamamoto. 2000. Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins. Cell 103:865-875.
31. Motohashi, H., T. O'Connor, F. Katsuoka, J. D. Engel, and M. Yamamoto. 2002. Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors. Gene 294:1-12. (Pubitemid 35291008)
32. Motohashi, H., F. Katsuoka, J. D. Engel, and M. Yamamoto. 2004. Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. Proc. Natl. Acad. Sci. U. S. A. 101:6379-6384.
33. Motohashi, H., F. Katsuoka, C. Miyoshi, Y. Uchimura, H. Saitoh, C. Francastel, J. D. Engel, and M. Yamamoto. 2006. MafG sumoylation is required for active transcriptional repression. Mol. Cell. Biol. 26:4652-4663.
34. Motohashi, H., M. Kimura, R. Fujita, A. Inoue, X. Pan, M. Takayama, F. Katsuoka, H. Aburatani, E. H. Bresnick, and M. Yamamoto. 2010. NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation. Blood 115:677-686.
35. Nagai, T., K. Igarashi, J. Akasaka, K. Furuyama, H. Fujita, N. Hayashi, M. Yamamoto, and S. Sassa. 1998. Regulation of NF-E2 activity in erythroleukemia cell differentiation. J. Biol. Chem. 273:5358-5365.
36. Onodera, K., J. A. Shavit, H. Motohashi, F. Katsuoka, J. E. Akasaka, J. D. Engel, and M. Yamamoto. 1999. Characterization of the murine mafF gene. J. Biol. Chem. 274:21162-21169.
37. Onodera, K., J. A. Shavit, H. Motohashi, M. Yamamoto, and D. J. Engel. 2000. Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice. EMBO J. 19:1335-1345.
38. Patturajan, M., X. Wei, R. Berezney, and J. L. Corden. 1998. A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II. Mol. Cell. Biol. 18:2406-2415.
39. Reyes, J. C., C. Muchardt, and M. Yaniv. 1997. Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix. J. Cell Biol. 137:263-274.
40. Sachdev, S., L. Bruhn, H. Sieber, A. Lichler, F. Melchior, and R. Grosschedl. 2001. PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev. 15:3088-3103.
41. Saijo, M., T. Hirai, A. Ogawa, A. Kobayashi, S. Kamiuchi, and K. Tanaka. 2007. Functionl TFIIH is required for UV-induced translocation of CSA to the nuclear matrix. Mol. Cell. Biol. 27:2538-2547.
42. Schmid, M., G. Arib, C. Laemmli, J. Nishikawa, T. Durussel, and U. K. Laemmli. 2006. Nup-PI: the nucleopore-promoter interaction of genes in yeast. Mol. Cell 21:379-391.
43. Schoenfelder, S., T. Sexton, L. Chakalova, N. F. Cope, A. Horton, S. Andrews, S. Kurukuti, J. A. Mitchell, D. Umlauf, D. S. Dimitrova, C. H. Eskiw, Y. Luo, C.-L. Wei, Y. Ruan, J. J. Bieker, and P. Fraser. 2010. Preferential association between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat. Genet. 42:53-62.
44. Shavit, J. A., H. Motohashi, K. Onodera, J. Akasaka, M. Yamamoto, and J. D. Engel. 1998. Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. Genes Dev. 12:2164-2174.
45. Shivdasani, R. A., M. F. Rosenblatt, D. Zucker-Franklin, C. W. Jackson, P. Hunt, C. J. M. Saris, and S. H. Orkin. 1995. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell 81:695-704.
46. Stein, G. S., S. K. Zaidi, C. D. Braastad, M. Montecino, A. J. van Wijnen, J.-Y. Choi, J. L. Stein, J. B. Lian, and A. Javed. 2003. Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair. Trends Cell. Biol. 13:584-592.
47. Sun, J., H. Hoshino, K. Takaku, O. Nakajima, A. Muto, H. Suzuki, S. Tashiro, S. Takahashi, S. Shibahara, J. Alam, M. M. Taketo, M. Yamamoto, and K. Igarashi. 2002. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J. 21:5216-5224.
48. Tiwari, S., J. E. Italiano, Jr., D. C. Barral, E. H. Mules, E. K. Novak, R. T. Swank, M. C. Seabra, and R. A. Shivdasani. 2003. A role for Rab27b in NF-E2-dependent pathways of platelet formation. Blood 102:3970-3979.
49. Yamamoto, T., M. Kyo, T. Kamiya, T. Tanaka, J. D. Engel, H. Motohashi, and M. Yamamoto. 2006. Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements. Genes Cells 11:575-591.
50. Zaidi, S. K., A. Javed, J.-Y. Choi, A. J. van Wijnen, J. L. Stein, J. B. Lian, and G. S. Stein. 2001. A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene. J. Cell Sci. 114:3093-3102.
51. Zhang, C., D. R. Dowd, A. Staal, C. Gu, J. B. Lian, A. J. van Wijnen, G. S. Stein, and P. N. MacDonald. 2003. Nucelar coactivator-p62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing. J. Biol. Chem. 278:35325-35336.
52. Zhao, R., M. S. Bodnar, and D. L. Spector. 2009. Nuclear neighborhoods and gene expression. Curr. Opin. Genet. Dev. 19:172-179.