Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 8, 2013, Pages

  Sips, Patrick Y ^a   Irie, Tomoya ^a   Zou, Lin ^a   Shinozaki, Shohei ^a   Sakai, Michihiro ^a   Shimizu, Nobuyuki ^a   Nguyen, Rebecca ^a   Stamler, Jonathan S ^b   Chao, Wei ^a   Kaneki, Masao ^a   Ichinose, Fumito ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Genetically modified mice; GSNOR; Myocardial depression; S nitrosylation; Sepsis

Indexed keywords

CALCIUM; GLUTATHIONE REDUCTASE; NITRIC OXIDE SYNTHASE; S NITROSOGLUTATHIONE REDUCTASE; UNCLASSIFIED DRUG; LIPOPOLYSACCHARIDE; NITRIC OXIDE; S NITROSOGLUTATHIONE REDUCTASE, MOUSE; S-NITROSOGLUTATHIONE REDUCTASE, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; GENOTYPE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; IN VIVO STUDY; MALE; MOUSE; MYOCARDIAL DEPRESSION; MYOCARDIAL DISEASE; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPTIC SHOCK; ANIMAL; C57BL MOUSE; CARDIOMYOPATHY; GENETICS; HEART CONTRACTION; HEART MUSCLE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; CALCIUM; CARDIOMYOPATHIES; GLUTATHIONE REDUCTASE; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SHOCK, SEPTIC;

MLCS; MLOWN;

EID: 84878434034     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00887.2012     Document Type: Article

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