Catalytic pocket inaccessibility of activation-induced cytidine deaminase is a safeguard against excessive mutagenic activity

Structure

Volumn 23, Issue 4, 2015, Pages 615-627

  King, Justin J ^a   Manuel, Courtney A ^a   Barrett, Crystal V ^a   Raber, Susanne ^a   Lucas, Heather ^a   Sutter, Patricia ^a   Larijani, Mani ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE; CYTIDINE DEAMINASE; DNA; PROTEIN BINDING;

AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR GENETICS; MOUSE; MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CYTIDINE; CYTIDINE DEAMINASE; DNA; HUMANS; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN BINDING;

EID: 84930190209     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2015.01.016     Document Type: Article

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