NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity

Nature Communications

Volumn 4, Issue , 2013, Pages

  Byeon, In Ja L ^a   Ahn, Jinwoo ^a   Mitra, Mithun ^b   Byeon, Chang Hyeock ^a   Hercík, Kamil ^b,c   Hritz, Jozef ^a,d   Charlton, Lisa M ^a   Levin, Judith G ^b   Gronenborn, Angela M ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^d MASARYK UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

APOBEC3A PROTEIN; CYTIDINE DEAMINASE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

CATALYSIS; ENZYME ACTIVITY; IMMUNE RESPONSE; MITOCHONDRIAL DNA; MOLECULAR ANALYSIS; NUCLEAR MAGNETIC RESONANCE; PATHOGEN; REAL TIME; SUBSTRATE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DEAMINATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PROTEIN DNA INTERACTION;

AMINO ACID SEQUENCE; BASE SEQUENCE; BIOCATALYSIS; CYTIDINE DEAMINASE; DEAMINATION; DEOXYCYTOSINE NUCLEOTIDES; DNA; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEINS; RNA; SOLUTIONS; SUBSTRATE SPECIFICITY; URIDINE TRIPHOSPHATE;

EID: 84878677763     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2883     Document Type: Article

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