-
1
-
-
79953881831
-
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
-
F. Anokye-Danso, C.M. Trivedi, D. Juhr, M. Gupta, Z. Cui, Y. Tian, Y. Zhang, W. Yang, P.J. Gruber, J.A. Epstein, and E.E. Morrisey Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency Cell Stem Cell 8 2011 376 388
-
(2011)
Cell Stem Cell
, vol.8
, pp. 376-388
-
-
Anokye-Danso, F.1
Trivedi, C.M.2
Juhr, D.3
Gupta, M.4
Cui, Z.5
Tian, Y.6
Zhang, Y.7
Yang, W.8
Gruber, P.J.9
Epstein, J.A.10
Morrisey, E.E.11
-
2
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
B.E. Bernstein, T.S. Mikkelsen, X. Xie, M. Kamal, D.J. Huebert, J. Cuff, B. Fry, A. Meissner, M. Wernig, and K. Plath et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells Cell 125 2006 315 326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
3
-
-
34548445454
-
Generation of induced pluripotent stem cells in the absence of drug selection
-
R. Blelloch, M. Venere, J. Yen, and M. Ramalho-Santos Generation of induced pluripotent stem cells in the absence of drug selection Cell Stem Cell 1 2007 245 247
-
(2007)
Cell Stem Cell
, vol.1
, pp. 245-247
-
-
Blelloch, R.1
Venere, M.2
Yen, J.3
Ramalho-Santos, M.4
-
4
-
-
84866369892
-
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
-
Y. Buganim, D.A. Faddah, A.W. Cheng, E. Itskovich, S. Markoulaki, K. Ganz, S.L. Klemm, A. van Oudenaarden, and R. Jaenisch Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase Cell 150 2012 1209 1222
-
(2012)
Cell
, vol.150
, pp. 1209-1222
-
-
Buganim, Y.1
Faddah, D.A.2
Cheng, A.W.3
Itskovich, E.4
Markoulaki, S.5
Ganz, K.6
Klemm, S.L.7
Van Oudenaarden, A.8
Jaenisch, R.9
-
5
-
-
82755185948
-
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells
-
B.W. Carey, S. Markoulaki, J.H. Hanna, D.A. Faddah, Y. Buganim, J. Kim, K. Ganz, E.J. Steine, J.P. Cassady, and M.P. Creyghton et al. Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells Cell Stem Cell 9 2011 588 598
-
(2011)
Cell Stem Cell
, vol.9
, pp. 588-598
-
-
Carey, B.W.1
Markoulaki, S.2
Hanna, J.H.3
Faddah, D.A.4
Buganim, Y.5
Kim, J.6
Ganz, K.7
Steine, E.J.8
Cassady, J.P.9
Creyghton, M.P.10
-
6
-
-
84881496104
-
Translatome analysis of CHO cells to identify key growth genes
-
F.C. Courtes, J. Lin, H.L. Lim, S.W. Ng, N.S. Wong, G. Koh, L. Vardy, M.G. Yap, B. Loo, and D.Y. Lee Translatome analysis of CHO cells to identify key growth genes J. Biotechnol. 167 2013 215 224
-
(2013)
J. Biotechnol.
, vol.167
, pp. 215-224
-
-
Courtes, F.C.1
Lin, J.2
Lim, H.L.3
Ng, S.W.4
Wong, N.S.5
Koh, G.6
Vardy, L.7
Yap, M.G.8
Loo, B.9
Lee, D.Y.10
-
7
-
-
2342489456
-
EIF-4E expression and its role in malignancies and metastases
-
A. De Benedetti, and J.R. Graff eIF-4E expression and its role in malignancies and metastases Oncogene 23 2004 3189 3199
-
(2004)
Oncogene
, vol.23
, pp. 3189-3199
-
-
De Benedetti, A.1
Graff, J.R.2
-
8
-
-
68549137933
-
Reprogramming and differentiation in mammals: Motifs and mechanisms
-
W.N. de Vries, A.V. Evsikov, L.J. Brogan, C.P. Anderson, J.H. Graber, B.B. Knowles, and D. Solter Reprogramming and differentiation in mammals: motifs and mechanisms Cold Spring Harb. Symp. Quant. Biol. 73 2008 33 38
-
(2008)
Cold Spring Harb. Symp. Quant. Biol.
, vol.73
, pp. 33-38
-
-
De Vries, W.N.1
Evsikov, A.V.2
Brogan, L.J.3
Anderson, C.P.4
Graber, J.H.5
Knowles, B.B.6
Solter, D.7
-
9
-
-
71249114806
-
Quantification of transforming capacity and cooperation of defined genetic alterations in myeloid malignancies
-
Y. Dogan, A. Ganser, M. Scherr, and M. Eder Quantification of transforming capacity and cooperation of defined genetic alterations in myeloid malignancies Exp. Hematol. 38 2010 11 19
-
(2010)
Exp. Hematol.
, vol.38
, pp. 11-19
-
-
Dogan, Y.1
Ganser, A.2
Scherr, M.3
Eder, M.4
-
10
-
-
77952967459
-
MTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
-
R.J. Dowling, I. Topisirovic, T. Alain, M. Bidinosti, B.D. Fonseca, E. Petroulakis, X. Wang, O. Larsson, A. Selvaraj, and Y. Liu et al. mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs Science 328 2010 1172 1176
-
(2010)
Science
, vol.328
, pp. 1172-1176
-
-
Dowling, R.J.1
Topisirovic, I.2
Alain, T.3
Bidinosti, M.4
Fonseca, B.D.5
Petroulakis, E.6
Wang, X.7
Larsson, O.8
Selvaraj, A.9
Liu, Y.10
-
11
-
-
77949383744
-
Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1
-
M.J. Edel, C. Menchon, S. Menendez, A. Consiglio, A. Raya, and J.C. Izpisua Belmonte Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1 Genes Dev. 24 2010 561 573
-
(2010)
Genes Dev.
, vol.24
, pp. 561-573
-
-
Edel, M.J.1
Menchon, C.2
Menendez, S.3
Consiglio, A.4
Raya, A.5
Izpisua Belmonte, J.C.6
-
13
-
-
84882291342
-
Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity
-
K. Feoktistova, E. Tuvshintogs, A. Do, and C.S. Fraser Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity Proc. Natl. Acad. Sci. USA 110 2013 13339 13344
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 13339-13344
-
-
Feoktistova, K.1
Tuvshintogs, E.2
Do, A.3
Fraser, C.S.4
-
14
-
-
77954386733
-
Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells
-
Y. Ge, F. Zhou, H. Chen, C. Cui, D. Liu, Q. Li, Z. Yang, G. Wu, S. Sun, and J. Gu et al. Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells Biochem. Biophys. Res. Commun. 397 2010 711 717
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.397
, pp. 711-717
-
-
Ge, Y.1
Zhou, F.2
Chen, H.3
Cui, C.4
Liu, D.5
Li, Q.6
Yang, Z.7
Wu, G.8
Sun, S.9
Gu, J.10
-
15
-
-
84868202020
-
Epigenetic obstacles encountered by transcription factors: Reprogramming against all odds
-
C.A. Gifford, and A. Meissner Epigenetic obstacles encountered by transcription factors: reprogramming against all odds Curr. Opin. Genet. Dev. 22 2012 409 415
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 409-415
-
-
Gifford, C.A.1
Meissner, A.2
-
16
-
-
0032520009
-
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway
-
A.C. Gingras, S.G. Kennedy, M.A. O'Leary, N. Sonenberg, and N. Hay 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway Genes Dev. 12 1998 502 513
-
(1998)
Genes Dev.
, vol.12
, pp. 502-513
-
-
Gingras, A.C.1
Kennedy, S.G.2
O'Leary, M.A.3
Sonenberg, N.4
Hay, N.5
-
17
-
-
0033153166
-
Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism
-
A.C. Gingras, S.P. Gygi, B. Raught, R.D. Polakiewicz, R.T. Abraham, M.F. Hoekstra, R. Aebersold, and N. Sonenberg Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism Genes Dev. 13 1999 1422 1437
-
(1999)
Genes Dev.
, vol.13
, pp. 1422-1437
-
-
Gingras, A.C.1
Gygi, S.P.2
Raught, B.3
Polakiewicz, R.D.4
Abraham, R.T.5
Hoekstra, M.F.6
Aebersold, R.7
Sonenberg, N.8
-
18
-
-
38849180436
-
Targeting the eukaryotic translation initiation factor 4E for cancer therapy
-
J.R. Graff, B.W. Konicek, J.H. Carter, and E.G. Marcusson Targeting the eukaryotic translation initiation factor 4E for cancer therapy Cancer Res. 68 2008 631 634
-
(2008)
Cancer Res.
, vol.68
, pp. 631-634
-
-
Graff, J.R.1
Konicek, B.W.2
Carter, J.H.3
Marcusson, E.G.4
-
19
-
-
84862777308
-
Direct reprogramming of fibroblasts into neural stem cells by defined factors
-
D.W. Han, N. Tapia, A. Hermann, K. Hemmer, S. Höing, M.J. Araúzo-Bravo, H. Zaehres, G. Wu, S. Frank, and S. Moritz et al. Direct reprogramming of fibroblasts into neural stem cells by defined factors Cell Stem Cell 10 2012 465 472
-
(2012)
Cell Stem Cell
, vol.10
, pp. 465-472
-
-
Han, D.W.1
Tapia, N.2
Hermann, A.3
Hemmer, K.4
Höing, S.5
Araúzo-Bravo, M.J.6
Zaehres, H.7
Wu, G.8
Frank, S.9
Moritz, S.10
-
20
-
-
41949098160
-
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
-
J. Hanna, S. Markoulaki, P. Schorderet, B.W. Carey, C. Beard, M. Wernig, M.P. Creyghton, E.J. Steine, J.P. Cassady, and R. Foreman et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency Cell 133 2008 250 264
-
(2008)
Cell
, vol.133
, pp. 250-264
-
-
Hanna, J.1
Markoulaki, S.2
Schorderet, P.3
Carey, B.W.4
Beard, C.5
Wernig, M.6
Creyghton, M.P.7
Steine, E.J.8
Cassady, J.P.9
Foreman, R.10
-
21
-
-
84866256464
-
An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors
-
J. He, L. Kang, T. Wu, J. Zhang, H. Wang, H. Gao, Y. Zhang, B. Huang, W. Liu, and Z. Kou et al. An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors Stem Cells Dev. 21 2012 2630 2641
-
(2012)
Stem Cells Dev.
, vol.21
, pp. 2630-2641
-
-
He, J.1
Kang, L.2
Wu, T.3
Zhang, J.4
Wang, H.5
Gao, H.6
Zhang, Y.7
Huang, B.8
Liu, W.9
Kou, Z.10
-
22
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
H. Hong, K. Takahashi, T. Ichisaka, T. Aoi, O. Kanagawa, M. Nakagawa, K. Okita, and S. Yamanaka Suppression of induced pluripotent stem cell generation by the p53-p21 pathway Nature 460 2009 1132 1135
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
Aoi, T.4
Kanagawa, O.5
Nakagawa, M.6
Okita, K.7
Yamanaka, S.8
-
23
-
-
84881256653
-
Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds
-
P. Hou, Y. Li, X. Zhang, C. Liu, J. Guan, H. Li, T. Zhao, J. Ye, W. Yang, and K. Liu et al. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds Science 341 2013 651 654
-
(2013)
Science
, vol.341
, pp. 651-654
-
-
Hou, P.1
Li, Y.2
Zhang, X.3
Liu, C.4
Guan, J.5
Li, H.6
Zhao, T.7
Ye, J.8
Yang, W.9
Liu, K.10
-
24
-
-
84862777192
-
The translational landscape of mTOR signalling steers cancer initiation and metastasis
-
A.C. Hsieh, Y. Liu, M.P. Edlind, N.T. Ingolia, M.R. Janes, A. Sher, E.Y. Shi, C.R. Stumpf, C. Christensen, and M.J. Bonham et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis Nature 485 2012 55 61
-
(2012)
Nature
, vol.485
, pp. 55-61
-
-
Hsieh, A.C.1
Liu, Y.2
Edlind, M.P.3
Ingolia, N.T.4
Janes, M.R.5
Sher, A.6
Shi, E.Y.7
Stumpf, C.R.8
Christensen, C.9
Bonham, M.J.10
-
25
-
-
75149196287
-
The mechanism of eukaryotic translation initiation and principles of its regulation
-
R.J. Jackson, C.U. Hellen, and T.V. Pestova The mechanism of eukaryotic translation initiation and principles of its regulation Nat. Rev. Mol. Cell Biol. 11 2010 113 127
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 113-127
-
-
Jackson, R.J.1
Hellen, C.U.2
Pestova, T.V.3
-
26
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
R. Jaenisch, and R. Young Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming Cell 132 2008 567 582
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
27
-
-
66149160608
-
Embryonic stem cell-specific microRNAs promote induced pluripotency
-
R.L. Judson, J.E. Babiarz, M. Venere, and R. Blelloch Embryonic stem cell-specific microRNAs promote induced pluripotency Nat. Biotechnol. 27 2009 459 461
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 459-461
-
-
Judson, R.L.1
Babiarz, J.E.2
Venere, M.3
Blelloch, R.4
-
28
-
-
40049108316
-
Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids
-
P. Kannan-Thulasiraman, B. Dolniak, S. Kaur, A. Sassano, D.V. Kalvakolanu, N. Hay, and L.C. Platanias Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids Biochem. Biophys. Res. Commun. 368 2008 983 989
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.368
, pp. 983-989
-
-
Kannan-Thulasiraman, P.1
Dolniak, B.2
Kaur, S.3
Sassano, A.4
Kalvakolanu, D.V.5
Hay, N.6
Platanias, L.C.7
-
29
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
T. Kawamura, J. Suzuki, Y.V. Wang, S. Menendez, L.B. Morera, A. Raya, G.M. Wahl, and J.C. Izpisúa Belmonte Linking the p53 tumour suppressor pathway to somatic cell reprogramming Nature 460 2009 1140 1144
-
(2009)
Nature
, vol.460
, pp. 1140-1144
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
Menendez, S.4
Morera, L.B.5
Raya, A.6
Wahl, G.M.7
Izpisúa Belmonte, J.C.8
-
30
-
-
33846581017
-
Histocompatible embryonic stem cells by parthenogenesis
-
K. Kim, P. Lerou, A. Yabuuchi, C. Lengerke, K. Ng, J. West, A. Kirby, M.J. Daly, and G.Q. Daley Histocompatible embryonic stem cells by parthenogenesis Science 315 2007 482 486
-
(2007)
Science
, vol.315
, pp. 482-486
-
-
Kim, K.1
Lerou, P.2
Yabuuchi, A.3
Lengerke, C.4
Ng, K.5
West, J.6
Kirby, A.7
Daly, M.J.8
Daley, G.Q.9
-
31
-
-
34548440698
-
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer
-
K. Kim, K. Ng, P.J. Rugg-Gunn, J.H. Shieh, O. Kirak, R. Jaenisch, T. Wakayama, M.A. Moore, R.A. Pedersen, and G.Q. Daley Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer Cell Stem Cell 1 2007 346 352
-
(2007)
Cell Stem Cell
, vol.1
, pp. 346-352
-
-
Kim, K.1
Ng, K.2
Rugg-Gunn, P.J.3
Shieh, J.H.4
Kirak, O.5
Jaenisch, R.6
Wakayama, T.7
Moore, M.A.8
Pedersen, R.A.9
Daley, G.Q.10
-
32
-
-
66049143859
-
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
-
D. Kim, C.H. Kim, J.I. Moon, Y.G. Chung, M.Y. Chang, B.S. Han, S. Ko, E. Yang, K.Y. Cha, R. Lanza, and K.S. Kim Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins Cell Stem Cell 4 2009 472 476
-
(2009)
Cell Stem Cell
, vol.4
, pp. 472-476
-
-
Kim, D.1
Kim, C.H.2
Moon, J.I.3
Chung, Y.G.4
Chang, M.Y.5
Han, B.S.6
Ko, S.7
Yang, E.8
Cha, K.Y.9
Lanza, R.10
Kim, K.S.11
-
33
-
-
70349687407
-
Direct reprogramming of human neural stem cells by OCT4
-
649-3
-
J.B. Kim, B. Greber, M.J. Araúzo-Bravo, J. Meyer, K.I. Park, H. Zaehres, and H.R. Schöler Direct reprogramming of human neural stem cells by OCT4 Nature 461 2009 649-3
-
(2009)
Nature
, vol.461
-
-
Kim, J.B.1
Greber, B.2
Araúzo-Bravo, M.J.3
Meyer, J.4
Park, K.I.5
Zaehres, H.6
Schöler, H.R.7
-
34
-
-
59349108302
-
Oct4-induced pluripotency in adult neural stem cells
-
J.B. Kim, V. Sebastiano, G. Wu, M.J. Araúzo-Bravo, P. Sasse, L. Gentile, K. Ko, D. Ruau, M. Ehrich, and D. van den Boom et al. Oct4-induced pluripotency in adult neural stem cells Cell 136 2009 411 419
-
(2009)
Cell
, vol.136
, pp. 411-419
-
-
Kim, J.B.1
Sebastiano, V.2
Wu, G.3
Araúzo-Bravo, M.J.4
Sasse, P.5
Gentile, L.6
Ko, K.7
Ruau, D.8
Ehrich, M.9
Van Den Boom, D.10
-
35
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
K. Kim, A. Doi, B. Wen, K. Ng, R. Zhao, P. Cahan, J. Kim, M.J. Aryee, H. Ji, and L.I. Ehrlich et al. Epigenetic memory in induced pluripotent stem cells Nature 467 2010 285 290
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
Ng, K.4
Zhao, R.5
Cahan, P.6
Kim, J.7
Aryee, M.J.8
Ji, H.9
Ehrlich, L.I.10
-
36
-
-
79957613988
-
Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors
-
J. Kim, C.J. Lengner, O. Kirak, J. Hanna, J.P. Cassady, M.A. Lodato, S. Wu, D.A. Faddah, E.J. Steine, and Q. Gao et al. Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors Stem Cells 29 2011 992 1000
-
(2011)
Stem Cells
, vol.29
, pp. 992-1000
-
-
Kim, J.1
Lengner, C.J.2
Kirak, O.3
Hanna, J.4
Cassady, J.P.5
Lodato, M.A.6
Wu, S.7
Faddah, D.A.8
Steine, E.J.9
Gao, Q.10
-
37
-
-
0026723117
-
MRNAs containing extensive secondary structure in their 5′ non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E
-
A.E. Koromilas, A. Lazaris-Karatzas, and N. Sonenberg mRNAs containing extensive secondary structure in their 5′ non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E EMBO J. 11 1992 4153 4158
-
(1992)
EMBO J.
, vol.11
, pp. 4153-4158
-
-
Koromilas, A.E.1
Lazaris-Karatzas, A.2
Sonenberg, N.3
-
38
-
-
0025915957
-
Quantitative analysis of protein synthesis in mouse embryos. I. Extensive reprogramming at the one- and two-cell stages
-
K.E. Latham, J.I. Garrels, C. Chang, and D. Solter Quantitative analysis of protein synthesis in mouse embryos. I. Extensive reprogramming at the one- and two-cell stages Development 112 1991 921 932
-
(1991)
Development
, vol.112
, pp. 921-932
-
-
Latham, K.E.1
Garrels, J.I.2
Chang, C.3
Solter, D.4
-
39
-
-
70450160004
-
Systems-level dynamic analyses of fate change in murine embryonic stem cells
-
R. Lu, F. Markowetz, R.D. Unwin, J.T. Leek, E.M. Airoldi, B.D. MacArthur, A. Lachmann, R. Rozov, A. Ma'ayan, and L.A. Boyer et al. Systems-level dynamic analyses of fate change in murine embryonic stem cells Nature 462 2009 358 362
-
(2009)
Nature
, vol.462
, pp. 358-362
-
-
Lu, R.1
Markowetz, F.2
Unwin, R.D.3
Leek, J.T.4
Airoldi, E.M.5
Macarthur, B.D.6
Lachmann, A.7
Rozov, R.8
Ma'Ayan, A.9
Boyer, L.A.10
-
40
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
R.M. Marión, K. Strati, H. Li, M. Murga, R. Blanco, S. Ortega, O. Fernandez-Capetillo, M. Serrano, and M.A. Blasco A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity Nature 460 2009 1149 1153
-
(2009)
Nature
, vol.460
, pp. 1149-1153
-
-
Marión, R.M.1
Strati, K.2
Li, H.3
Murga, M.4
Blanco, R.5
Ortega, S.6
Fernandez-Capetillo, O.7
Serrano, M.8
Blasco, M.A.9
-
42
-
-
55849117368
-
Generation of mouse induced pluripotent stem cells without viral vectors
-
K. Okita, M. Nakagawa, H. Hyenjong, T. Ichisaka, and S. Yamanaka Generation of mouse induced pluripotent stem cells without viral vectors Science 322 2008 949 953
-
(2008)
Science
, vol.322
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
43
-
-
0028034233
-
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function
-
A. Pause, G.J. Belsham, A.C. Gingras, O. Donzé, T.A. Lin, J.C. Lawrence Jr., and N. Sonenberg Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5′-cap function Nature 371 1994 762 767
-
(1994)
Nature
, vol.371
, pp. 762-767
-
-
Pause, A.1
Belsham, G.J.2
Gingras, A.C.3
Donzé, O.4
Lin, T.A.5
Lawrence Jr., J.C.6
Sonenberg, N.7
-
44
-
-
70350494540
-
P53-dependent translational control of senescence and transformation via 4E-BPs
-
E. Petroulakis, A. Parsyan, R.J. Dowling, O. LeBacquer, Y. Martineau, M. Bidinosti, O. Larsson, T. Alain, L. Rong, and Y. Mamane et al. p53-dependent translational control of senescence and transformation via 4E-BPs Cancer Cell 16 2009 439 446
-
(2009)
Cancer Cell
, vol.16
, pp. 439-446
-
-
Petroulakis, E.1
Parsyan, A.2
Dowling, R.J.3
Lebacquer, O.4
Martineau, Y.5
Bidinosti, M.6
Larsson, O.7
Alain, T.8
Rong, L.9
Mamane, Y.10
-
45
-
-
0032577691
-
4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family
-
F. Poulin, A.C. Gingras, H. Olsen, S. Chevalier, and N. Sonenberg 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family J. Biol. Chem. 273 1998 14002 14007
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14002-14007
-
-
Poulin, F.1
Gingras, A.C.2
Olsen, H.3
Chevalier, S.4
Sonenberg, N.5
-
46
-
-
45749141224
-
Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs
-
L. Rong, M. Livingstone, R. Sukarieh, E. Petroulakis, A.C. Gingras, K. Crosby, B. Smith, R.D. Polakiewicz, J. Pelletier, M.A. Ferraiuolo, and N. Sonenberg Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs RNA 14 2008 1318 1327
-
(2008)
RNA
, vol.14
, pp. 1318-1327
-
-
Rong, L.1
Livingstone, M.2
Sukarieh, R.3
Petroulakis, E.4
Gingras, A.C.5
Crosby, K.6
Smith, B.7
Polakiewicz, R.D.8
Pelletier, J.9
Ferraiuolo, M.A.10
Sonenberg, N.11
-
47
-
-
0027365517
-
Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E
-
I.B. Rosenwald, A. Lazaris-Karatzas, N. Sonenberg, and E.V. Schmidt Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E Mol. Cell. Biol. 13 1993 7358 7363
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7358-7363
-
-
Rosenwald, I.B.1
Lazaris-Karatzas, A.2
Sonenberg, N.3
Schmidt, E.V.4
-
48
-
-
42649126705
-
A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation
-
P. Sampath, D.K. Pritchard, L. Pabon, H. Reinecke, S.M. Schwartz, D.R. Morris, and C.E. Murry A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation Cell Stem Cell 2 2008 448 460
-
(2008)
Cell Stem Cell
, vol.2
, pp. 448-460
-
-
Sampath, P.1
Pritchard, D.K.2
Pabon, L.3
Reinecke, H.4
Schwartz, S.M.5
Morris, D.R.6
Murry, C.E.7
-
49
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
B. Schwanhäusser, D. Busse, N. Li, G. Dittmar, J. Schuchhardt, J. Wolf, W. Chen, and M. Selbach Global quantification of mammalian gene expression control Nature 473 2011 337 342
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanhäusser, B.1
Busse, D.2
Li, N.3
Dittmar, G.4
Schuchhardt, J.5
Wolf, J.6
Chen, W.7
Selbach, M.8
-
50
-
-
77952172633
-
Dynamic single-cell imaging of direct reprogramming reveals an early specifying event
-
Z.D. Smith, I. Nachman, A. Regev, and A. Meissner Dynamic single-cell imaging of direct reprogramming reveals an early specifying event Nat. Biotechnol. 28 2010 521 526
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 521-526
-
-
Smith, Z.D.1
Nachman, I.2
Regev, A.3
Meissner, A.4
-
51
-
-
60149091189
-
Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
-
N. Sonenberg, and A.G. Hinnebusch Regulation of translation initiation in eukaryotes: mechanisms and biological targets Cell 136 2009 731 745
-
(2009)
Cell
, vol.136
, pp. 731-745
-
-
Sonenberg, N.1
Hinnebusch, A.G.2
-
52
-
-
39149115929
-
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
-
M. Stadtfeld, N. Maherali, D.T. Breault, and K. Hochedlinger Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse Cell Stem Cell 2 2008 230 240
-
(2008)
Cell Stem Cell
, vol.2
, pp. 230-240
-
-
Stadtfeld, M.1
Maherali, N.2
Breault, D.T.3
Hochedlinger, K.4
-
53
-
-
84890275857
-
Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells
-
T. Stoyanova, A.R. Cooper, J.M. Drake, X. Liu, A.J. Armstrong, K.J. Pienta, H. Zhang, D.B. Kohn, J. Huang, O.N. Witte, and A.S. Goldstein Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells Proc. Natl. Acad. Sci. USA 110 2013 20111 20116
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20111-20116
-
-
Stoyanova, T.1
Cooper, A.R.2
Drake, J.M.3
Liu, X.4
Armstrong, A.J.5
Pienta, K.J.6
Zhang, H.7
Kohn, D.B.8
Huang, J.9
Witte, O.N.10
Goldstein, A.S.11
-
54
-
-
79955780736
-
Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
-
D. Subramanyam, S. Lamouille, R.L. Judson, J.Y. Liu, N. Bucay, R. Derynck, and R. Blelloch Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells Nat. Biotechnol. 29 2011 443 448
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 443-448
-
-
Subramanyam, D.1
Lamouille, S.2
Judson, R.L.3
Liu, J.Y.4
Bucay, N.5
Derynck, R.6
Blelloch, R.7
-
55
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
56
-
-
84880651864
-
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts
-
K. Tanabe, M. Nakamura, M. Narita, K. Takahashi, and S. Yamanaka Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts Proc. Natl. Acad. Sci. USA 110 2013 12172 12179
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 12172-12179
-
-
Tanabe, K.1
Nakamura, M.2
Narita, M.3
Takahashi, K.4
Yamanaka, S.5
-
57
-
-
84860527756
-
A unifying model for mTORC1-mediated regulation of mRNA translation
-
C.C. Thoreen, L. Chantranupong, H.R. Keys, T. Wang, N.S. Gray, and D.M. Sabatini A unifying model for mTORC1-mediated regulation of mRNA translation Nature 485 2012 109 113
-
(2012)
Nature
, vol.485
, pp. 109-113
-
-
Thoreen, C.C.1
Chantranupong, L.2
Keys, H.R.3
Wang, T.4
Gray, N.S.5
Sabatini, D.M.6
-
58
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
J. Utikal, J.M. Polo, M. Stadtfeld, N. Maherali, W. Kulalert, R.M. Walsh, A. Khalil, J.G. Rheinwald, and K. Hochedlinger Immortalization eliminates a roadblock during cellular reprogramming into iPS cells Nature 460 2009 1145 1148
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
Maherali, N.4
Kulalert, W.5
Walsh, R.M.6
Khalil, A.7
Rheinwald, J.G.8
Hochedlinger, K.9
-
60
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
L. Warren, P.D. Manos, T. Ahfeldt, Y.H. Loh, H. Li, F. Lau, W. Ebina, P.K. Mandal, Z.D. Smith, and A. Meissner et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA Cell Stem Cell 7 2010 618 630
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
Ebina, W.7
Mandal, P.K.8
Smith, Z.D.9
Meissner, A.10
-
61
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
J. Yu, M.A. Vodyanik, K. Smuga-Otto, J. Antosiewicz-Bourget, J.L. Frane, S. Tian, J. Nie, G.A. Jonsdottir, V. Ruotti, and R. Stewart et al. Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
-
62
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
H. Zhou, S. Wu, J.Y. Joo, S. Zhu, D.W. Han, T. Lin, S. Trauger, G. Bien, S. Yao, and Y. Zhu et al. Generation of induced pluripotent stem cells using recombinant proteins Cell Stem Cell 4 2009 381 384
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
Zhu, S.4
Han, D.W.5
Lin, T.6
Trauger, S.7
Bien, G.8
Yao, S.9
Zhu, Y.10
-
63
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
R. Zoncu, A. Efeyan, and D.M. Sabatini mTOR: from growth signal integration to cancer, diabetes and ageing Nat. Rev. Mol. Cell Biol. 12 2011 21 35
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
|