Iron oxide nanoparticle toxicity testing using high-throughput analysis and high-content imaging

Nanotoxicology

Volumn 9, Issue S1, 2015, Pages 87-94

  Harris, Georgina ^a   Palosaari, Taina ^a   Magdolenova, Zuzana ^b   Mennecozzi, Milena ^a   Gineste, Jean Michel ^a   Saavedra, Luis ^a   Milcamps, Anne ^a   Huk, Anna ^b   Collins, Andrew Richard ^c   Dusinska, Maria ^b   Whelan, Maurice ^a  

^a JOINT RESEARCH CENTRE   (Italy)

^b NORWEGIAN INSTITUTE FOR AIR RESEARCH   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

DNA damage; High content imaging; High throughput nanotoxicology; Iron oxide nanoparticles; Oxidative stress

Indexed keywords

8 HYDROXYGUANINE; DNA; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; IRON OXIDE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; ROTENONE; STAUROSPORINE; FERRIC ION; FERRIC OXIDE; MAGNETITE NANOPARTICLE;

3T3 CELL LINE; ANIMAL CELL; ARTICLE; AUTOMATION; CELL VIABILITY; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COS 1 CELL LINE; CYTOTOXICITY; CYTOTOXICITY TEST; DNA DAMAGE; DNA STRAND BREAKAGE; FENTON REACTION; FIBROBLAST; FLUORESCENCE; GENOTOXICITY; HIGH THROUGHPUT SCREENING; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY CHAIN; ANIMAL; CELL LINE; CELL SURVIVAL; CHLOROCEBUS AETHIOPS; DOSE RESPONSE; DRUG EFFECTS; PROCEDURES; TOXICITY TESTING;

MAMMALIA;

ANIMALS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; COMET ASSAY; DOSE-RESPONSE RELATIONSHIP, DRUG; FERRIC COMPOUNDS; HIGH-THROUGHPUT SCREENING ASSAYS; MAGNETITE NANOPARTICLES; MICE; OXIDATIVE STRESS; TOXICITY TESTS;

EID: 84930001498     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2013.816797     Document Type: Article

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