Interaction of functionalized superparamagnetic iron oxide nanoparticles with brain structures

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 1, 2006, Pages 108-116

  Cengelli, Feride ^a   Maysinger, Dusica ^b   Tschudi Monnet, Florianne ^c   Montet, Xavier ^d   Corot, Claire ^e   Petri Fink, Alke ^f   Hofmann, Heinrich ^f   Juillerat Jeanneret, Lucienne ^a  

^a UNIVERSITY INSTITUTE OF PATHOLOGY   (Switzerland)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e Laboratoire Guerbet   (France)

^f EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN; IRON OXIDE; NANOPARTICLE; NITRIC OXIDE; POLYVINYL ALCOHOL; SUPERPARAMAGNETIC IRON OXIDE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BRAIN; BRAIN CELL; CELL ACTIVATION; CELL AGGREGATION; CELL INTERACTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG UPTAKE; EMBRYO; ENDOTHELIUM CELL; FLUORESCENCE; INFLAMMATION; MAGNET; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; CELLS, CULTURED; FERRIC COMPOUNDS; MAGNETIC RESONANCE IMAGING; MICE; MICE, INBRED C57BL; NANOSTRUCTURES; RATS;

EID: 33745245298     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.101915     Document Type: Article

References (40)

1. Alexiou C, Arnold W, Klein RJ, Parak FG, Hulin P, Bergemann C, Erhardt W, Wagenpfeil S, and Lübbe AS (2000) Locoregional cancer treatment with magnetic drug targeting. Cancer Res 60:6641-6648.
2. Borm PJ and Kreyling W (2004) Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery. J Nanosci Nanotechnol 4:521-531.
3. Brigger I, Dubernet C, and Couvreur P (2002) Nanoparticles in cancer therapy and diagnosis. Adv Drug Deliv Rev 54:631-651.
4. Chastellain M, Petri A, and Hofmann H (2004) Particle size investigations on a multi-step synthesis of PVA coated superparamagnetic nanoparticles. J Colloid Interface Sci 278:353-360.
5. Chellat F, Merhi Y, Moreau A, and Yahia L (2005) Therapeutic potential of nanoparticulate systems for macrophage targeting. Biomaterials 26:7260-7275.
6. Colvin VL (2003) The potential environmental impact of engineered nanomaterials. Nat Biotech 21:1166-1170.
7. Corot C, Petry KG, Trivedi R, Saleh A, Jonkmanns C, Le Bas JF, Blezer E, Rausch M, Brochet B, Foster-Gareau P, et al. (2004) Macrophage imaging in central nervous system and in carotid atherosclerotic plaque using ultrasmall superparamagnetic iron oxide in magnetic resonance imaging. Investig Radiol 39:619-625.
8. Daldrup-Link HE, Rudelius M, Piontek G, Metz S, Brauer R, Debus G, Corot C, Schlegel J, Link TM, Peschel C, et al. (2005) Migration of iron oxide-labeled human hematopoietic progenitor cells in a mouse model: in vivo monitoring with 1.5-T MR imaging equipment. Radiology 234:197-205.
9. Hoehn M, Kustermann E, Blunk J, Wiedermann D, Trapp T, Wecker S, Focking M, Arnold H, Hescheler J, Fleischmann BK, et al. (2002) Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci USA 99:16267-16272.
10. Hoet PHM, Brüske-Hohlfeld I, and Salata OV (2004) Nanoparticles - known and unknown health risks. J Nanobiotechnol 2:12-27.
11. Honegger P and Tschudi-Monnet F (2000) Aggregating neural cell cultures, in Protocols for Neural Cell Culture (Fedoroff S and Richardson A eds) pp 199-218, Humana Press, Inc., Totowa, NJ.
12. Juillerat-Jeanneret L, Aguzzi A, Wiestler OD, Darekar P, and Janzer RC (1992) Dexamethasone regulates the activity of enzymatic markers of cerebral endothelial cell lines. In Vitro Cell Dev Biol 28A:537-543.
13. Juillerat-Jeanneret L, Monnet-Tschudi F, Zürich MG, Lohm S, Duijvestijn AM, and Honegger P (2003) Regulation of peptidase activity in a three-dimensional aggregate model of brain tumor vasculature. Cell Tissue Res 311:53-59.
14. Kandimalla KK and Donovan MD (2005) Carrier mediated transport of chlorpheniramine and chlorcyclizine across bovine olfactory mucosa: implications on noseto-brain transport. J Pharm Sci 94:613-624.
15. Kircher MF, Mahmood U, King RS, Weissleder R, and Josephson L (2003) A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. Cancer Res 63:8122-8125.
16. Koch AM, Reynolds F, Merkle HP, Weissleder R, and Josephson L (2005) Transport of surface-modified nanoparticles through cell monolayers. Chem Biol Chem 6:337-345.
17. Kreuter J (2004) Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain. J Nanosci Nanotechnol 4:484-488.
18. Lockman PR, Koziara JM, Mumper RJ, and Allen DD (2004) Nanoparticle surface charges alter blood-brain barrier integrity and permeability. J Drug Target 12:635-641.
19. Lockman PR, Oyewumi MO, Koziara JM, Roder KE, Mumper RJ, and Allen DD (2003) Brain uptake of thiamine-coated nanoparticles. J Control Rel 93:271-282.
20. Lubbe AS, Bergemann C, Huhnt W, Fricke T, Riess H, Brock JW, and Huhn D (1996) Preclinical experiences with magnetic drug targeting: tolerance and efficacy. Cancer Res 56:4694-4701.
21. Massart R, Dubois E, Cabuil V, and Hasmonay E (1995) Preparation and properties of monodisperse magnetic fluids. J Magn Magn Mater 149:1-5.
22. Muldoon LL, Pagel MA, Kroll RA, Roman-Goldstein S, Jones RS, and Neuwelt EA (1999) A physiological barrier distal to the anatomic blood-brain barrier in a model of transvascular delivery. Am J Neuroradiol 20:217-222.
23. Muller RH and Keck CM (2004) Drug delivery to the brain: realization by novel drug carriers. J Nanosci Nanotechnol 4:471-483.
24. Murata JI, Betz Corradin S, Janzer RC, and Juillerat-Jeanneret L (1994) Tumor cells suppress cytokine-induced nitric oxide (NO) production in cerebral endothelial cells. Int J Cancer 59:699-705.
25. Murata JI, Ricciardi-Castagnoli P, Dessous L'Eglise Mange P, Martin F, and Juillerat-Jeanneret L (1997) Microglial cells induce cytotoxic effects towards colon carcinoma cells: measurement of tumor cytotoxicity with a g-glutamyl transpeptidase assay. Int J Cancer 70:169-174.
26. Neuwelt EA, Varallyay P, Bago AG, Muldoon LL, Nesbit G, and Nixon R (2004) Imaging of iron oxide nanoparticles by MR and light microscopy in patients with malignant brain tumors. Neuropathol Appl Neurobiol 30:456-471.
27. Obersdörster G, Sharp Z, Atudorei V, Elder A, Gelein R, Kreyling W, and Cox C (2004) Translocation of inhaled ultrafine particles to the brain. Inhalation Toxicol 16:437-445.
28. Perry VH, Andersson PB, and Gordon S (1993) Macrophages and inflammation in the central nervous system. Trends Neurol Sci 16:268-273.
29. Petri-Fink A, Chastellain M, Juillerat-Jeanneret L, Ferrari A, and Hofmann H (2005) Development of functionalized superparamagnetic iron oxide nanoparticles for interaction with human cancer cells. Biomaterials 26:639-646.
30. Raynal I, Rrigent P, Peyramaure S, Najid A, Rebuzzi C, and Corot C (2004) Macrophage endocytosis of superparamagnetic iron oxide nanoparticles: mechanisms and comparison of ferumoxides and ferumoxtran-10. Investig Radiol 39:56-63.
31. Risau W and Wolburg W (1990) Development of blood-brain barrier. Trends Neurol Sci 13:174-178.
32. Rudge S, Peterson C, Vessely C, Koda J, Stevens S, and Catterall L (2001) Adsorption and desorption of chemotherapeutic drugs from a magnetically targeted carrier (MTC). J Control Rel 74:335-340.
33. Ruehm SG, Corot C, Vogt P, Kolb S, and Debatin JF (2001) Magnetic resonance imaging of atherosclerotic plaque with ultrasmall superparamagnetic particles of iron oxide in hyperlipidemic rabbits. Circulation 103:415-422.
34. Savic R, Luo L, Eisenberg A, and Maysinger D (2003) Micellar nanocontainers distribute to defined cytoplasmic organelles. Science (Wash DC) 300:615-618.
35. Sundstrom JB, Mao H, Santoianni R, Villinger F, Little DM, Huynh TT, Mayne AE, Hao E, and Ansari AA (2004) Magnetic resonance imaging of activated proliferating rhesus macaque T cells labeled with superparamagnetic monocrystalline iron oxide nanoparticles. J Acquir Immune Defic Syndr 35:9-21.
36. Triverdi RA, U-King-Im JM, Graves MJ, Cross JJ, Horsley J, Goddard MJ, Skepper JN, Quartey G, Warburton E, Joubert I, et al. (2004) In vivo detection of macrophages in human carotid atheroma: temporal dependence of ultrasmall superparamagnetic particles of iron oxide-enhanced MRI. Stroke 35:1631-1635.
37. van Ewijk GA, Vroege GJ, and Philipse AP (1999) Convenient preparation methods for magnetic colloids. J Magn Magn Mater 201:31-33.
38. Weissleder R, Cheng HC, Bogdanova A, and Bogdanov A (1997) Magnetically-labeled cells can be detected by MR imaging. J Magn Reson Imaging 7:258-263.
39. Wilhelm C, Billotey C, Roger J, Pons JN, Bacri JC, and Gazeau F (2003) Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating. Biomaterials 24:1001-1011.
40. Zhang Y, Kohler N, and Zhang M (2002) Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake. Biomaterials 23:1553-1561.