Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells

ACS Nano

Volumn 5, Issue 4, 2011, Pages 2756-2769

  Zhang, Haiyuan ^a   Xia, Tian ^a   Meng, Huan ^a   Xue, Min ^a   George, Saji ^a   Ji, Zhaoxia ^a   Wang, Xiang ^a   Liu, Rong ^a   Wang, Meiying ^a   France, Bryan ^a   Rallo, Robert ^a   Damoiseaux, Robert ^a   Cohen, Yoram ^a   Bradley, Kenneth A ^a   Zink, Jeffrey I ^a   Nel, Andre E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cationic nanoparticles; differentiation; polyethyleneimine (PEI); primary epithelial cells; toxicity

Indexed keywords

CATIONIC NANOPARTICLES; CELL SURFACES; CELLULAR DIFFERENTIATION; CYTOTOXIC; DIFFERENTIAL EXPRESSIONS; DIFFERENTIATED CELLS; DIFFERENTIATION; ENGINEERED NANOMATERIALS; HEPARIN SULFATES; HIGH MOLECULAR WEIGHT; HUMAN BRONCHIAL EPITHELIAL CELLS; IN-VITRO; IN-VIVO; MESOPOROUS SILICA NANOPARTICLES; POLYETHYLENEIMINE; POLYETHYLENEIMINE (PEI); PRE-TREATMENT; PRIMARY CELLS; PRIMARY EPITHELIAL CELLS; PROTEOGLYCANS; SIDE CHAINS; SYNDECAN-1;

CELL MEMBRANES; CYTOTOXICITY; MOLECULAR WEIGHT; NANOPARTICLES; POLYMERS; SILICA; TOXIC MATERIALS;

PLASTIC COATINGS;

CATION; NANOPARTICLE; SYNDECAN 1;

ARTICLE; BRONCHUS; CELL CULTURE; CELL DIFFERENTIATION; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; ERYTHROCYTE; HEMOLYSIS; HUMAN; METABOLISM; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

BLOTTING, WESTERN; BRONCHI; CATIONS; CELL DIFFERENTIATION; CELLS, CULTURED; EPITHELIAL CELLS; ERYTHROCYTES; HEMOLYSIS; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; SYNDECAN-1;

EID: 79955366583     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn200328m     Document Type: Article

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