Enhanced M1 and impaired M2 macrophage polarization and reduced mitochondrial biogenesis via inhibition of AMP kinase in chronic kidney disease

Cellular Physiology and Biochemistry

Volumn 36, Issue 1, 2015, Pages 358-372

  Li, Cong ^a   Ding, Xiao Yan ^a   Xiang, Dong Mei ^a   Xu, Jie ^a   Huang, Xiang Lan ^a   Hou, Fan Fan ^a   Zhou, Qiu Gen ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Chronic inflammation; Chronic kidney disease; Macrophage; Mitochondrial biogenesis; Polarization

Indexed keywords

ADENOSINE PHOSPHATE; ADENYLATE KINASE; CD206 ANTIGEN; CREATININE; INOSINATE DEHYDROGENASE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LYMPHOCYTE ANTIGEN; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; BONE MARROW DERIVED MACROPHAGE; CHRONIC KIDNEY DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME INHIBITION; EX VIVO STUDY; MALE; MITOCHONDRION; NONHUMAN; PERITONEUM MACROPHAGE; POLARIZATION; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CHRONIC KIDNEY FAILURE; DISEASE MODEL; METABOLISM; OSTEOCLAST;

RATTUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BIOMARKERS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; MACROPHAGES, PERITONEAL; MALE; MITOCHONDRIA; OSTEOCLASTS; RATS; RENAL INSUFFICIENCY, CHRONIC;

EID: 84929930195     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430106     Document Type: Article

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