AMP-activated protein kinase activation by 5-aminoimidazole-4-carbox-amide- 1-β-d-ribofuranoside (aicar) reduces lipoteichoic acid-induced lung inflammation

Journal of Biological Chemistry

Volumn 288, Issue 10, 2013, Pages 7047-7052

  Hoogendijk, Arie J ^a,b   Pinhanços, Sandra S ^a,b   Van Der Poll, Tom ^a,b   Wieland, Catharina W ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b Center for Experimental Molecular Medicine   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALVEOLAR MACROPHAGES; AMP-ACTIVATED PROTEIN KINASE; CYTOKINE PRODUCTION; CYTOKINES; IN-VITRO; IN-VIVO; LUNG INFLAMMATION;

BIOLOGICAL ORGANS; CELL CULTURE; CHEMICAL ACTIVATION;

PATHOLOGY;

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYL COENZYME A CARBOXYLASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACETYL-COA CARBOXYLASE; AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CHEMOKINES; ENZYME ACTIVATION; FEMALE; HYPOGLYCEMIC AGENTS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; NEUTROPHILS; PHOSPHORYLATION; PNEUMONIA; RIBONUCLEOTIDES; TEICHOIC ACIDS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874822756     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.413138     Document Type: Article

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