-
1
-
-
67650874081
-
Cancer statistics 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J and Thun MJ: Cancer statistics, 2009. CA Cancer J Clin 59: 225-249, 2009.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
67649440886
-
The biology of ovarian cancer: New opportunities for translation
-
Bast RC Jr, Hennessy B and Mills GB: The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer 9: 415-428, 2009.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 415-428
-
-
Bast Jr., R.C.1
Hennessy, B.2
Mills, G.B.3
-
3
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
DOI 10.1126/science.1099993
-
Shintani T and Klionsky DJ: Autophagy in health and disease: a double-edged sword. Science 306: 990-995, 2004. (Pubitemid 39482894)
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
4
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B and Kroemer G: Autophagy in the pathogenesis of disease. Cell 132: 27-42, 2008.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
5
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fghts disease through cellular self-digestion. Nature 451: 1069-1075, 2008. (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
6
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
DOI 10.1038/nrm2239, PII NRM2239
-
Maiuri MC, Zalckvar E, Kimchi A and Kroemer G: Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752, 2007. (Pubitemid 47312826)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
7
-
-
56749170677
-
Autophagic cell death: The story of a misnomer
-
Kroemer G and Levine B: Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 9: 1004-1010, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
8
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
DOI 10.1038/nrc1692, PII N1692
-
Kondo Y, Kanzawa T, Sawaya R and Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5: 726-734, 2005. (Pubitemid 41486365)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.9
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
9
-
-
0030049234
-
A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation
-
DOI 10.1097/00007890-199601270-00006
-
Suzuki S, Enosawa S, Kakefuda T, Shinomiya T, Amari M, Naoe S, Hoshino Y and Chiba K: A novel immunosup-pressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation. Transplantation 61: 200-205, 1996. (Pubitemid 26046580)
-
(1996)
Transplantation
, vol.61
, Issue.2
, pp. 200-205
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
Shinomiya, T.4
Amari, M.5
Naoe, S.6
Hoshino, Y.7
Chiba, K.8
-
10
-
-
0030248747
-
Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats
-
Suzuki S, Enosawa S, Kakefuda T, Li XK, Mitsusada M, Takahara S and Amemiya H: Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats. Transpl Immunol 4: 252-455, 1996.
-
(1996)
Transpl Immunol
, vol.4
, pp. 252-455
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
Li, X.K.4
Mitsusada, M.5
Takahara, S.6
Amemiya, H.7
-
11
-
-
20544456156
-
FTY720, a novel immunomodulator: Efficacy and safety results from the first phase 2a study in de novo renal transplantation
-
DOI 10.1097/01.TP.0000121761.02129.A6
-
Tedesco-Silva H, Mourad G, Kahan BD, Boira JG, Weimar W, Mulgaonkar S, Nashan B, Madsen S, Charpentier B, Pellet P and Vanrenterghem Y: FTY720, a novel immunomodulator: effcacy and safety results from the frst phase 2A study in de novo renal transplantation. Transplantation 77: 1826-1833, 2004. (Pubitemid 38822204)
-
(2004)
Transplantation
, vol.77
, Issue.12
, pp. 1826-1833
-
-
Tedesco-Silva, H.1
Mourad, G.2
Kahan, B.D.3
Boira, J.G.4
Weimar, W.5
Mulgaonkar, S.6
Nashan, B.7
Madsen, S.8
Charpentier, B.9
Pellet, P.10
Vanrenterghem, Y.11
-
12
-
-
84856249964
-
Fingolimod for multiple sclerosis
-
Pelletier D and Hafer DA: Fingolimod for multiple sclerosis. N Engl J Med 366: 339-347, 2012.
-
(2012)
N Engl J Med
, vol.366
, pp. 339-347
-
-
Pelletier, D.1
Hafer, D.A.2
-
13
-
-
51749100808
-
The role of sphin-gosine kinase 1 in cancer: Oncogene or non-oncogene addiction?
-
Vadas M, Xia P, McCaughan G and Gamble J: The role of sphin-gosine kinase 1 in cancer: oncogene or non-oncogene addiction? Biochim Biophys Acta 1781: 442-447, 2008.
-
(2008)
Biochim Biophys Acta
, vol.1781
, pp. 442-447
-
-
Vadas, M.1
Xia, P.2
McCaughan, G.3
Gamble, J.4
-
14
-
-
78649305851
-
FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy
-
Zhang N, Qi Y, Wadham C, Wang L, Warren A, Di W and Xia P: FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy. Autophagy 6: 1157-1167, 2010.
-
(2010)
Autophagy
, vol.6
, pp. 1157-1167
-
-
Zhang, N.1
Qi, Y.2
Wadham, C.3
Wang, L.4
Warren Di A, W.5
Xia, P.6
-
15
-
-
70349333252
-
Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway
-
Sukocheva O, Wang L, Verrier E, Vadas MA and Xia P: Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway. Endocrinology 150: 4484-4492, 2009.
-
(2009)
Endocrinology
, vol.150
, pp. 4484-4492
-
-
Sukocheva, O.1
Wang, L.2
Verrier, E.3
Vadas, M.A.4
Xia, P.5
-
16
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou TC and Talalay P: Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22: 27-55, 1984.
-
(1984)
Adv Enzyme Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
17
-
-
33748794547
-
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
-
Chou TC: Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58: 621-681, 2006.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 621-681
-
-
Chou, T.C.1
-
18
-
-
70649107674
-
Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: Therapeutic potential for ovarian cancer
-
Zhang N, Wu ZM, McGowan E, Shi J, Hong ZB, Ding CW, Xia P and Di W: Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: therapeutic potential for ovarian cancer. Cancer Sci 100: 2459-2464, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 2459-2464
-
-
Zhang, N.1
Wu, Z.M.2
McGowan, E.3
Shi, J.4
Hong, Z.B.5
Ding, C.W.6
Xia, P.7
Di, W.8
-
19
-
-
0043240182
-
Ovarian cancer: Strategies for overcoming resistance to chemotherapy
-
Agarwal R and Kaye SB: Ovarian cancer: strategies for overcoming resistance to chemotherapy. Nat Rev Cancer 3: 502-516, 2003. (Pubitemid 37328838)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.7
, pp. 502-516
-
-
Agarwal, R.1
Kaye, S.B.2
-
20
-
-
57649101120
-
Platinum compounds 30 years after the introduction of cisplatin: Implications for the treatment of ovarian cancer
-
Muggia F: Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer. Gynecol Oncol 112: 275-281, 2009.
-
(2009)
Gynecol Oncol
, vol.112
, pp. 275-281
-
-
Muggia, F.1
-
22
-
-
0347986620
-
12 myotubes
-
DOI 10.1042/BJ20030826
-
Tassa A, Roux MP, Attaix D and Bechet DM: Class III phos-phoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes. Biochem J 376: 577-586, 2003. (Pubitemid 38058057)
-
(2003)
Biochemical Journal
, vol.376
, Issue.3
, pp. 577-586
-
-
Tassa, A.1
Roux, M.P.2
Attaix, D.3
Bechet, D.M.4
-
23
-
-
84255176452
-
FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death
-
Alinari L, Mahoney E, Patton J, Zhang X, Huynh L, Earl CT, Mani R, Mao Y, Yu B, Quinion C, Towns WH, Chen CS, Goldenberg DM, Blum KA, Byrd JC, Muthusamy N, Praetorius-Ibba M and Baiocchi RA: FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death. Blood 118: 6893-6903, 2011.
-
(2011)
Blood
, vol.118
, pp. 6893-6903
-
-
Alinari, L.1
Mahoney, E.2
Patton, J.3
Zhang, X.4
Huynh, L.5
Earl, C.T.6
Mani, R.7
Mao, Y.8
Yu, B.9
Quinion, C.10
Towns, W.H.11
Chen, C.S.12
Goldenberg, D.M.13
Blum, K.A.14
Byrd, J.C.15
Muthusamy, N.16
Praetorius-Ibba, M.17
Baiocchi, R.A.18
-
24
-
-
80053259864
-
Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins
-
Romero Rosales K, Singh G, Wu K, Chen J, Janes MR, Lilly MB, Peralta ER, Siskind LJ, Bennett MJ, Fruman DA and Edinger AL: Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins. Biochem J 439: 299-311, 2011.
-
(2011)
Biochem J
, vol.439
, pp. 299-311
-
-
Romero Rosales, K.1
Singh, G.2
Wu, K.3
Chen, J.4
Janes, M.R.5
Lilly, M.B.6
Peralta, E.R.7
Siskind, L.J.8
Bennett, M.J.9
Fruman, D.A.10
Edinger, A.L.11
-
25
-
-
79959948518
-
FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells
-
Wallington-Beddoe CT, Hewson J, Bradstock KF and Bendall LJ: FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells. Autophagy 7: 707-715, 2011.
-
(2011)
Autophagy
, vol.7
, pp. 707-715
-
-
Wallington-Beddoe, C.T.1
Hewson, J.2
Bradstock, K.F.3
Bendall, L.J.4
-
26
-
-
84862829250
-
Autophagy induced by FTY720 promotes apoptosis in U266 cells
-
Liao A, Hu R, Zhao Q, Li J, Li Y, Yao K, Zhang R, Wang H, Yang W and Liu Z: Autophagy induced by FTY720 promotes apoptosis in U266 cells. Eur J Pharm Sci 45: 600-605, 2012.
-
(2012)
Eur J Pharm Sci
, vol.45
, pp. 600-605
-
-
Liao, A.1
Hu, R.2
Zhao, Q.3
Li, J.4
Li, Y.5
Yao, K.6
Zhang, R.7
Wang, H.8
Yang, W.9
Liu, Z.10
-
27
-
-
0035863399
-
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
-
Paglin S, Hollister T, Delohery T, Hackett N, McMahill M, Sphicas E, Domingo D and Yahalom J: A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 61: 439-444, 2001. (Pubitemid 32128593)
-
(2001)
Cancer Research
, vol.61
, Issue.2
, pp. 439-444
-
-
Paglin, S.1
Hollister, T.2
Delohery, T.3
Hackett, N.4
McMahill, M.5
Sphicas, E.6
Domingo, D.7
Yahalom, J.8
-
28
-
-
1842865745
-
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
-
DOI 10.1038/sj.cdd.4401359
-
Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y and Kondo S: Role of autophagy in temozolomide-induced cyto-toxicity for malignant glioma cells. Cell Death Differ 11: 448-457, 2004. (Pubitemid 38489422)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 448-457
-
-
Kanzawa, T.1
Germano, I.M.2
Komata, T.3
Ito, H.4
Kondo, Y.5
Kondo, S.6
-
29
-
-
35448980704
-
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
-
DOI 10.1158/0008-5472.CAN-07-1462
-
Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, Ueno T, Ochiai A and Esumi H: Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res 67: 9677-9684, 2007. (Pubitemid 47621214)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9677-9684
-
-
Sato, K.1
Tsuchihara, K.2
Fujii, S.3
Sugiyama, M.4
Goya, T.5
Atomi, Y.6
Ueno, T.7
Ochiai, A.8
Esumi, H.9
-
30
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
DOI 10.1172/JCI28833
-
Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, Thomas-Tikhonenko A and Thompson CB: Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 117: 326-336, 2007. (Pubitemid 46203961)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.2
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
Evan, G.I.6
Thomas-Tikhonenko, A.7
Thompson, C.B.8
-
31
-
-
40449086885
-
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy
-
DOI 10.1158/0008-5472.CAN-07-0562
-
Apel A, Herr I, Schwarz H, Rodemann HP and Mayer A: Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy. Cancer Res 68: 1485-1494, 2008. (Pubitemid 351346857)
-
(2008)
Cancer Research
, vol.68
, Issue.5
, pp. 1485-1494
-
-
Apel, A.1
Herr, I.2
Schwarz, H.3
Rodemann, H.P.4
Mayer, A.5
-
32
-
-
66449122303
-
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
-
Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, Galavotti S, Young KW, Selmi T, Yacobi R, Van Etten RA, Donato N, Hunter A, Dinsdale D, Tirrò E, Vigneri P, Nicotera P, Dyer MJ, Holyoake T, Salomoni P and Calabretta B: Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 119: 1109-1123, 2009.
-
(2009)
J Clin Invest
, vol.119
, pp. 1109-1123
-
-
Bellodi, C.1
Lidonnici, M.R.2
Hamilton, A.3
Helgason, G.V.4
Soliera, A.R.5
Ronchetti, M.6
Galavotti, S.7
Young, K.W.8
Selmi, T.9
Yacobi, R.10
Van Etten, R.A.11
Donato, N.12
Hunter, A.13
Dinsdale, D.14
Tirrò, E.15
Vigneri, P.16
Nicotera, P.17
Dyer, M.J.18
Holyoake, T.19
Salomoni, P.20
Calabretta, B.21
more..
|