-
1
-
-
84864425173
-
Old drugs, new purpose: Retooling existing drugs for optimized treatment of resistant tuberculosis
-
K. E. Dooley, C. D. Mitnick, M. A. De Groote, E. Obuku, V. Belitsky, C. D. Hamilton, M. Makhene, S. Shah, J. C M. Brust, N. Durakovic, E. Nuermberger, Old drugs, new purpose: Retooling existing drugs for optimized treatment of resistant tuberculosis. Clin. Infect. Dis. 55, 572-581 (2012).
-
(2012)
Clin. Infect. Dis.
, vol.55
, pp. 572-581
-
-
Dooley, K.E.1
Mitnick, C.D.2
De Groote, M.A.3
Obuku, E.4
Belitsky, V.5
Hamilton, C.D.6
Makhene, M.7
Shah, S.8
Brust, J.C.M.9
Durakovic, N.10
Nuermberger, E.11
-
2
-
-
2142760947
-
Antimicrobial pharmacodynamics: Critical interactions of "bug and drug"
-
G. L. Drusano, Antimicrobial pharmacodynamics: Critical interactions of "bug and drug". Nat. Rev. Microbiol. 2, 289-300 (2004).
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 289-300
-
-
Drusano, G.L.1
-
3
-
-
44449148293
-
The impact of medication regimen factors on adherence to chronic treatment: A review of literature
-
K. S. Ingersoll, J. Cohen, The impact of medication regimen factors on adherence to chronic treatment: A review of literature. J. Behav. Med. 31, 213-224 (2008).
-
(2008)
J. Behav. Med.
, vol.31
, pp. 213-224
-
-
Ingersoll, K.S.1
Cohen, J.2
-
4
-
-
70349634546
-
Effect of duration and intermittency of rifampin on tuberculosis treatment outcomes: A systematic review and meta-analysis
-
D. Menzies, A. Benedetti, A. Paydar, I. Martin, S. Royce, M. Pai, A. Vernon, C. Lienhardt, W. Burman, Effect of duration and intermittency of rifampin on tuberculosis treatment outcomes: A systematic review and meta-analysis. PLOS Med. 6, e1000146 (2009).
-
(2009)
PLOS Med.
, vol.6
, pp. e1000146
-
-
Menzies, D.1
Benedetti, A.2
Paydar, A.3
Martin, I.4
Royce, S.5
Pai, M.6
Vernon, A.7
Lienhardt, C.8
Burman, W.9
-
5
-
-
80054123332
-
Treatment of tuberculosis and optimal dosing schedules
-
K. C. Chang, C. C. Leung, J. Grosset, W. W. Yew, Treatment of tuberculosis and optimal dosing schedules. Thorax 66, 997-1007 (2011).
-
(2011)
Thorax
, vol.66
, pp. 997-1007
-
-
Chang, K.C.1
Leung, C.C.2
Grosset, J.3
Yew, W.W.4
-
6
-
-
84903756577
-
Intermittent versus daily therapy for treating tuberculosis in children
-
A. Bose, S. Kalita, W. Rose, P. Tharyan, Intermittent versus daily therapy for treating tuberculosis in children. Cochrane Database Syst. Rev. 1, CD007953 (2014).
-
(2014)
Cochrane Database Syst. Rev.
, vol.1
, pp. CD007953
-
-
Bose, A.1
Kalita, S.2
Rose, W.3
Tharyan, P.4
-
7
-
-
84862530678
-
Malachite green interferes with postantibiotic recovery of mycobacteria
-
E. Gelman, J. D. McKinney, N. Dhar, Malachite green interferes with postantibiotic recovery of mycobacteria. Antimicrob. Agents Chemother. 56, 3610-3614 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 3610-3614
-
-
Gelman, E.1
McKinney, J.D.2
Dhar, N.3
-
8
-
-
0027236995
-
Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem
-
I. Odenholt-Tornqvist, Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem. J. Antimicrob. Chemother. 31, 881-892 (1993).
-
(1993)
J. Antimicrob. Chemother.
, vol.31
, pp. 881-892
-
-
Odenholt-Tornqvist, I.1
-
9
-
-
84877267006
-
Advances in the development of new tuberculosis drugs and treatment regimens
-
A. Zumla, P. Nahid, S. T. Cole, Advances in the development of new tuberculosis drugs and treatment regimens. Nat. Rev. Drug Discov. 12, 388-404 (2013).
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 388-404
-
-
Zumla, A.1
Nahid, P.2
Cole, S.T.3
-
10
-
-
84897414453
-
DALI: Defining antibiotic levels in intensive care unit patients: Are current β-lactam antibiotic doses sufficient for critically ill patients?
-
J. A. Roberts, S. K. Paul, M. Akova, M. Bassetti, J. J. De Waele, G. Dimopoulos, K. M. Kaukonen, D. Koulenti, C. Martin, P. Montravers, DALI: Defining antibiotic levels in intensive care unit patients: Are current β-lactam antibiotic doses sufficient for critically ill patients? Clin. Infect. Dis. 58, 1072-1083 (2014).
-
(2014)
Clin. Infect. Dis.
, vol.58
, pp. 1072-1083
-
-
Roberts, J.A.1
Paul, S.K.2
Akova, M.3
Bassetti, M.4
De Waele, J.J.5
Dimopoulos, G.6
Kaukonen, K.M.7
Koulenti, D.8
Martin, C.9
Montravers, P.10
-
11
-
-
62549089300
-
Functional relationship between bacterial cell density and the efficacy of antibiotics
-
K. I. Udekwu, N. Parrish, P. Ankomah, F. Baquero, B. R. Levin, Functional relationship between bacterial cell density and the efficacy of antibiotics. J. Antimicrob. Chemother. 63, 745-757 (2009).
-
(2009)
J. Antimicrob. Chemother.
, vol.63
, pp. 745-757
-
-
Udekwu, K.I.1
Parrish, N.2
Ankomah, P.3
Baquero, F.4
Levin, B.R.5
-
12
-
-
1542317089
-
Quorum sensing in Staphylococcus aureus biofilms
-
J. M. Yarwood, D. J. Bartels, E. M. Volper, E. P. Greenberg, Quorum sensing in Staphylococcus aureus biofilms. J. Bacteriol. 186, 1838-1850 (2004).
-
(2004)
J. Bacteriol.
, vol.186
, pp. 1838-1850
-
-
Yarwood, J.M.1
Bartels, D.J.2
Volper, E.M.3
Greenberg, E.P.4
-
13
-
-
0016789374
-
Effect of inoculum and of beta-lactamase on the anti-staphylococcal activity of thirteen penicillins and cephalosporins
-
L. D. Sabath, C. Garner, C. Wilcox, M. Finland, Effect of inoculum and of beta-lactamase on the anti-staphylococcal activity of thirteen penicillins and cephalosporins. Antimicrob. Agents Chemother. 8, 344-349 (1975).
-
(1975)
Antimicrob. Agents Chemother.
, vol.8
, pp. 344-349
-
-
Sabath, L.D.1
Garner, C.2
Wilcox, C.3
Finland, M.4
-
14
-
-
0027285367
-
Penicillin-binding protein expression at different growth stages determines penicillin efficacy in vitro and in vivo: An explanation for the inoculum effect
-
D. L. Stevens, S. Yan, A. E. Bryant, Penicillin-binding protein expression at different growth stages determines penicillin efficacy in vitro and in vivo: An explanation for the inoculum effect. J. Infect. Dis. 167, 1401-1405 (1993).
-
(1993)
J. Infect. Dis.
, vol.167
, pp. 1401-1405
-
-
Stevens, D.L.1
Yan, S.2
Bryant, A.E.3
-
15
-
-
79952032570
-
Population biological principles of drug-resistance evolution in infectious diseases
-
P. A. Zur Wiesch, R. Kouyos, J. Engelstädter, R. R. Regoes, S. Bonhoeffer, Population biological principles of drug-resistance evolution in infectious diseases. Lancet Infect. Dis. 11, 236-247 (2011).
-
(2011)
Lancet Infect. Dis.
, vol.11
, pp. 236-247
-
-
Zur Wiesch, P.A.1
Kouyos, R.2
Engelstädter, J.3
Regoes, R.R.4
Bonhoeffer, S.5
-
17
-
-
84903279007
-
A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents: Investigating practice gaps and potential cost-savings
-
Y. H. Lee, G. Liu, D. M. Thiboutot, D. L. Leslie, J. S. Kirby, A retrospective analysis of the duration of oral antibiotic therapy for the treatment of acne among adolescents: Investigating practice gaps and potential cost-savings. J. Am. Acad. Dermatol. 71, 70-76 (2014).
-
(2014)
J. Am. Acad. Dermatol.
, vol.71
, pp. 70-76
-
-
Lee, Y.H.1
Liu, G.2
Thiboutot, D.M.3
Leslie, D.L.4
Kirby, J.S.5
-
18
-
-
84900296078
-
Comparing short to standard duration of antibiotic therapy for patients hospitalized with cellulitis (DANCE): Study protocol for a randomized controlled trial
-
D. R. Cranendonk, B. C. Opmeer, J. M. Prins, W. J. Wiersinga, Comparing short to standard duration of antibiotic therapy for patients hospitalized with cellulitis (DANCE): Study protocol for a randomized controlled trial. BMC Infect. Dis. 14, 235 (2014).
-
(2014)
BMC Infect. Dis.
, vol.14
, pp. 235
-
-
Cranendonk, D.R.1
Opmeer, B.C.2
Prins, J.M.3
Wiersinga, W.J.4
-
19
-
-
84875895689
-
Procalcitoninguided algorithm to reduce length of antibiotic therapy in patients with severe sepsis and septic shock
-
A. Hohn, S. Schroeder, A. Gehrt, K. Bernhardt, B. Bein, K. Wegscheider, M. Hochreiter, Procalcitoninguided algorithm to reduce length of antibiotic therapy in patients with severe sepsis and septic shock. BMC Infect. Dis. 13, 158 (2013).
-
(2013)
BMC Infect. Dis.
, vol.13
, pp. 158
-
-
Hohn, A.1
Schroeder, S.2
Gehrt, A.3
Bernhardt, K.4
Bein, B.5
Wegscheider, K.6
Hochreiter, M.7
-
20
-
-
84896455574
-
New antituberculosis drugs, regimens, and adjunct therapies: Needs, advances, and future prospects
-
A. I. Zumla, S. H. Gillespie, M. Hoelscher, P. P. J. Philips, S. T. Cole, I. Abubakar, T. D. McHugh, M. Schito, M. Maeurer, A. J. Nunn, New antituberculosis drugs, regimens, and adjunct therapies: Needs, advances, and future prospects. Lancet Infect. Dis. 14, 327-340 (2014).
-
(2014)
Lancet Infect. Dis.
, vol.14
, pp. 327-340
-
-
Zumla, A.I.1
Gillespie, S.H.2
Hoelscher, M.3
Philips, P.P.J.4
Cole, S.T.5
Abubakar, I.6
McHugh, T.D.7
Schito, M.8
Maeurer, M.9
Nunn, A.J.10
-
21
-
-
84890257761
-
Short-vs long-duration antibiotic regimens for ventilator-associated pneumonia: A systematic review and meta-analysis
-
G. Dimopoulos, G. Poulakou, I. A. Pneumatikos, A. Armaganidis, M. H. Kollef, D. K. Matthaiou, Short-vs long-duration antibiotic regimens for ventilator-associated pneumonia: A systematic review and meta-analysis. Chest 144, 1759-1767 (2013).
-
(2013)
Chest
, vol.144
, pp. 1759-1767
-
-
Dimopoulos, G.1
Poulakou, G.2
Pneumatikos, I.A.3
Armaganidis, A.4
Kollef, M.H.5
Matthaiou, D.K.6
-
22
-
-
0032481410
-
Low dosage and long treatment duration of β-lactam: Risk factors for carriage of penicillin-resistant Streptococcus pneumoniae
-
D. Guillemot, C. Carbon, B. Balkau, P. Geslin, H. Lecoeur, F. Vauzelle-Kervroëdan, G. Bouvenot, E. Eschwége, Low dosage and long treatment duration of β-lactam: Risk factors for carriage of penicillin-resistant Streptococcus pneumoniae. JAMA 279, 365-370 (1998).
-
(1998)
JAMA
, vol.279
, pp. 365-370
-
-
Guillemot, D.1
Carbon, C.2
Balkau, B.3
Geslin, P.4
Lecoeur, H.5
Vauzelle-Kervroëdan, F.6
Bouvenot, G.7
Eschwége, E.8
-
23
-
-
4644343922
-
Bacterial persistence as a phenotypic switch
-
N. Q. Balaban, J. Merrin, R. Chait, L. Kowalik, S. Leibler, Bacterial persistence as a phenotypic switch. Science 305, 1622-1625 (2004).
-
(2004)
Science
, vol.305
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
24
-
-
84880428168
-
A problem of persistence: Still more questions than answers?
-
N. Q. Balaban, K. Gerdes, K. Lewis, J. D. McKinney, A problem of persistence: Still more questions than answers? Nat. Rev. Microbiol. 11, 587-591 (2013).
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 587-591
-
-
Balaban, N.Q.1
Gerdes, K.2
Lewis, K.3
McKinney, J.D.4
-
25
-
-
84879072389
-
Microbial persistence and the road to drug resistance
-
N. R. Cohen, M. A. Lobritz, J. J. Collins, Microbial persistence and the road to drug resistance. Cell Host Microbe 13, 632-642 (2013).
-
(2013)
Cell Host Microbe
, vol.13
, pp. 632-642
-
-
Cohen, N.R.1
Lobritz, M.A.2
Collins, J.J.3
-
26
-
-
74249107300
-
SOS response induces persistence to fluoroquinolones in Escherichia coli
-
T. Dörr, K. Lewis, M. Vulic, SOS response induces persistence to fluoroquinolones in Escherichia coli. PLOS Genet. 5, e1000760 (2009).
-
(2009)
PLOS Genet.
, vol.5
, pp. e1000760
-
-
Dörr, T.1
Lewis, K.2
Vulic, M.3
-
27
-
-
84891926324
-
Growth feedback as a basis for persister bistability
-
J. Feng, D. A. Kessler, E. Ben-Jacob, H. Levine, Growth feedback as a basis for persister bistability. Proc. Natl. Acad. Sci. U. S. A. 111, 544-549 (2014).
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 544-549
-
-
Feng, J.1
Kessler, D.A.2
Ben-Jacob, E.3
Levine, H.4
-
28
-
-
84864349736
-
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals
-
S. S. Grant, B. B. Kaufmann, N. S. Chand, N. Haseley, D. T. Hung, Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. Proc. Natl. Acad. Sci. U. S. A. 109, 12147-12152 (2012).
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 12147-12152
-
-
Grant, S.S.1
Kaufmann, B.B.2
Chand, N.S.3
Haseley, N.4
Hung, D.T.5
-
29
-
-
84873485631
-
Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus
-
P. J. T. Johnson, B. R. Levin, Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus. PLOS Genet. 9, e1003123 (2013).
-
(2013)
PLOS Genet.
, vol.9
, pp. e1003123
-
-
Johnson, P.J.T.1
Levin, B.R.2
-
31
-
-
84871859996
-
Dynamic persistence of antibiotic-stressed mycobacteria
-
Y. Wakamoto, N. Dhar, R. Chait, K. Schneider, F. Signorino-Gelo, S. Leibler, J. D. McKinney, Dynamic persistence of antibiotic-stressed mycobacteria. Science 339, 91-95 (2013).
-
(2013)
Science
, vol.339
, pp. 91-95
-
-
Wakamoto, Y.1
Dhar, N.2
Chait, R.3
Schneider, K.4
Signorino-Gelo, F.5
Leibler, S.6
McKinney, J.D.7
-
32
-
-
77649174212
-
Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli
-
T. Dörr, M. Vulic, K. Lewis, Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli. PLOS Biol. 8, e1000317 (2010).
-
(2010)
PLOS Biol.
, vol.8
, pp. e1000317
-
-
Dörr, T.1
Vulic, M.2
Lewis, K.3
-
33
-
-
33845607284
-
Persister cells, dormancy and infectious disease
-
K. Lewis, Persister cells, dormancy and infectious disease. Nat. Rev. Microbiol. 5, 48-56 (2007).
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 48-56
-
-
Lewis, K.1
-
34
-
-
84907879368
-
Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations
-
O. Fridman, A. Goldberg, I. Ronin, N. Shoresh, N. Q. Balaban, Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations. Nature 513, 418-421 (2014).
-
(2014)
Nature
, vol.513
, pp. 418-421
-
-
Fridman, O.1
Goldberg, A.2
Ronin, I.3
Shoresh, N.4
Balaban, N.Q.5
-
36
-
-
84905403724
-
Antagonism between bacteriostatic and bactericidal antibiotics is prevalent
-
P. S. Ocampo, V. Lázár, B. Papp, M. Arnoldini, P. Abel Zur Wiesch, R. Busa-Fekete, G. Fekete, C. Pál, M. Ackermann, S. Bonhoeffer, Antagonism between bacteriostatic and bactericidal antibiotics is prevalent. Antimicrob. Agents Chemother. 58, 4573-4582 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4573-4582
-
-
Ocampo, P.S.1
Lázár, V.2
Papp, B.3
Arnoldini, M.4
Abel Zur Wiesch, P.5
Busa-Fekete, R.6
Fekete, G.7
Pál, C.8
Ackermann, M.9
Bonhoeffer, S.10
-
37
-
-
78449268845
-
Interdependence of cell growth and gene expression: Origins and consequences
-
M. Scott, C. W. Gunderson, E. M. Mateescu, Z. Zhang, T. Hwa, Interdependence of cell growth and gene expression: Origins and consequences. Science 330, 1099-1102 (2010).
-
(2010)
Science
, vol.330
, pp. 1099-1102
-
-
Scott, M.1
Gunderson, C.W.2
Mateescu, E.M.3
Zhang, Z.4
Hwa, T.5
-
38
-
-
0027230031
-
The postantibiotic effect of antimicrobial combinations in a neutropenic murine thigh infection model
-
S. Gudmundsson, S. Einarsson, H. Erlendsdottir, J. Moffat, W. Bayer, W. A. Craig, The postantibiotic effect of antimicrobial combinations in a neutropenic murine thigh infection model. J. Antimicrob. Chemother. 31(Suppl. D), 177-191 (1993).
-
(1993)
J. Antimicrob. Chemother.
, vol.31
, pp. 177-191
-
-
Gudmundsson, S.1
Einarsson, S.2
Erlendsdottir, H.3
Moffat, J.4
Bayer, W.5
Craig, W.A.6
-
39
-
-
0021344577
-
The postantibiotic effect in the treatment of experimental meningitis caused by Streptococcus pneumoniae in rabbits
-
M. G. Täuber, O. Zak, W. M. Scheld, B. Hengstler, M. A. Sande, The postantibiotic effect in the treatment of experimental meningitis caused by Streptococcus pneumoniae in rabbits. J. Infect. Dis. 149, 575-583 (1984).
-
(1984)
J. Infect. Dis.
, vol.149
, pp. 575-583
-
-
Täuber, M.G.1
Zak, O.2
Scheld, W.M.3
Hengstler, B.4
Sande, M.A.5
-
40
-
-
0027154004
-
Post-antibiotic effects in experimental infection models: Relationship to in-vitro phenomena and to treatment of infections in man
-
W. A. Craig, Post-antibiotic effects in experimental infection models: Relationship to in-vitro phenomena and to treatment of infections in man. J. Antimicrob. Chemother. 31(Suppl. D), 149-158 (1993).
-
(1993)
J. Antimicrob. Chemother.
, vol.31
, pp. 149-158
-
-
Craig, W.A.1
-
41
-
-
4644287346
-
Pharmacodynamic functions: A multiparameter approach to the design of antibiotic treatment regimens
-
R. R. Regoes, C. Wiuff, R. M. Zappala, K. N. Garner, F. Baquero, B. R. Levin, Pharmacodynamic functions: A multiparameter approach to the design of antibiotic treatment regimens. Antimicrob. Agents Chemother. 48, 3670-3676 (2004).
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 3670-3676
-
-
Regoes, R.R.1
Wiuff, C.2
Zappala, R.M.3
Garner, K.N.4
Baquero, F.5
Levin, B.R.6
-
42
-
-
84862765893
-
Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells
-
S. Bakshi, A. Siryaporn, M. Goulian, J. C. Weisshaar, Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells. Mol. Microbiol. 85, 21-38 (2012).
-
(2012)
Mol. Microbiol.
, vol.85
, pp. 21-38
-
-
Bakshi, S.1
Siryaporn, A.2
Goulian, M.3
Weisshaar, J.C.4
-
43
-
-
0018399333
-
The curve doses vs survival time in the evaluation of acute toxicity
-
L. Molinengo, The curve doses vs survival time in the evaluation of acute toxicity. J. Pharm. Pharmacol. 31, 343-344 (1979).
-
(1979)
J. Pharm. Pharmacol.
, vol.31
, pp. 343-344
-
-
Molinengo, L.1
-
44
-
-
14844348264
-
Molecular insights into aminoglycoside action and resistance
-
S. Magnet, J. S. Blanchard, Molecular insights into aminoglycoside action and resistance. Chem. Rev. 105, 477-498 (2005).
-
(2005)
Chem. Rev.
, vol.105
, pp. 477-498
-
-
Magnet, S.1
Blanchard, J.S.2
-
45
-
-
0019218755
-
In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae
-
R. Williamson, R. Hakenbeck, A. Tomasz, In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 18, 629-637 (1980).
-
(1980)
Antimicrob. Agents Chemother.
, vol.18
, pp. 629-637
-
-
Williamson, R.1
Hakenbeck, R.2
Tomasz, A.3
-
46
-
-
0028305362
-
Kinetics of penicillin binding to penicillinbinding proteins of Staphylococcus aureus
-
H. F. Chambers, M. J. Sachdeva, C. J. Hackbarth, Kinetics of penicillin binding to penicillinbinding proteins of Staphylococcus aureus. Biochem. J. 301(Pt. 1), 139-144 (1994).
-
(1994)
Biochem. J.
, vol.301
, pp. 139-144
-
-
Chambers, H.F.1
Sachdeva, M.J.2
Hackbarth, C.J.3
-
47
-
-
0029956443
-
Direct quantitation of the number of individual penicillin-binding proteins per cell in Escherichia coli
-
T. J. Dougherty, K. Kennedy, R. E. Kessler, M. J. Pucci, Direct quantitation of the number of individual penicillin-binding proteins per cell in Escherichia coli. J. Bacteriol. 178, 6110-6115 (1996).
-
(1996)
J. Bacteriol.
, vol.178
, pp. 6110-6115
-
-
Dougherty, T.J.1
Kennedy, K.2
Kessler, R.E.3
Pucci, M.J.4
-
48
-
-
0029817142
-
Simultaneous pharmacodynamic analysis of the lag and bactericidal phases exhibited by beta-lactams against Escherichia coli
-
R. C. Li, Simultaneous pharmacodynamic analysis of the lag and bactericidal phases exhibited by beta-lactams against Escherichia coli. Antimicrob. Agents Chemother. 40, 2306-2310 (1996).
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 2306-2310
-
-
Li, R.C.1
-
49
-
-
58149147307
-
A simple screen to identify promoters conferring high levels of phenotypic noise
-
N. E. Freed, O. K. Silander, B. Stecher, A. Böhm, W. D. Hardt, M. Ackermann, A simple screen to identify promoters conferring high levels of phenotypic noise. PLOS Genet. 4, e1000307 (2008).
-
(2008)
PLOS Genet.
, vol.4
, pp. e1000307
-
-
Freed, N.E.1
Silander, O.K.2
Stecher, B.3
Böhm, A.4
Hardt, W.D.5
Ackermann, M.6
-
50
-
-
84857480997
-
A genomewide analysis of promoter-mediated phenotypic noise in Escherichia coli
-
O. K. Silander, N. Nikolic, A. Zaslaver, A. Bren, I. Kikoin, U. Alon, M. Ackermann, A genomewide analysis of promoter-mediated phenotypic noise in Escherichia coli. PLOS Genet. 8, e1002443 (2012).
-
(2012)
PLOS Genet.
, vol.8
, pp. e1002443
-
-
Silander, O.K.1
Nikolic, N.2
Zaslaver, A.3
Bren, A.4
Kikoin, I.5
Alon, U.6
Ackermann, M.7
-
51
-
-
0038628994
-
Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days
-
A. Jindani, C. J. Doré, D. A. Mitchison, Bactericidal and sterilizing activities of antituberculosis drugs during the first 14 days. Am. J. Respir. Crit. Care Med. 167, 1348-1354 (2003).
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
, pp. 1348-1354
-
-
Jindani, A.1
Doré, C.J.2
Mitchison, D.A.3
-
52
-
-
0036919977
-
Rifampicin concentrations in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum following a single 600 mg oral dose in patients undergoing fibre-optic bronchoscopy
-
H. M. Ziglam, Rifampicin concentrations in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum following a single 600 mg oral dose in patients undergoing fibre-optic bronchoscopy. J. Antimicrob. Chemother. 50, 1011-1015 (2002).
-
(2002)
J. Antimicrob. Chemother.
, vol.50
, pp. 1011-1015
-
-
Ziglam, H.M.1
-
53
-
-
44449128516
-
Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption
-
J. J. Wilkins, R. M. Savic, M. O. Karlsson, G. Langdon, H. McIlleron, G. Pillai, P. J. Smith, U. S. Simonsson, Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption. Antimicrob. Agents Chemother. 52, 2138-2148 (2008).
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 2138-2148
-
-
Wilkins, J.J.1
Savic, R.M.2
Karlsson, M.O.3
Langdon, G.4
McIlleron, H.5
Pillai, G.6
Smith, P.J.7
Simonsson, U.S.8
-
54
-
-
33747436591
-
Persisters: A distinct physiological state of E
-
D. Shah, Z. Zhang, A. Khodursky, N. Kaldalu, K. Kurg, K. Lewis, Persisters: A distinct physiological state of E. coli. BMC Microbiol. 6, 53 (2006).
-
(2006)
Coli. BMC Microbiol.
, vol.6
, pp. 53
-
-
Shah, D.1
Zhang, Z.2
Khodursky, A.3
Kaldalu, N.4
Kurg, K.5
Lewis, K.6
-
55
-
-
84899505083
-
Molecular mechanisms underlying bacterial persisters
-
E. Maisonneuve, K. Gerdes, Molecular mechanisms underlying bacterial persisters. Cell 157, 539-548 (2014).
-
(2014)
Cell
, vol.157
, pp. 539-548
-
-
Maisonneuve, E.1
Gerdes, K.2
-
56
-
-
84892928454
-
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
-
B. Javid, F. Sorrentino, M. Toosky, W. Zheng, J. T. Pinkham, N. Jain, M. Pan, F. Deighan, E. J. Rubin, Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance. Proc. Natl. Acad. Sci. U. S. A. 111, 1132-1137 (2014).
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 1132-1137
-
-
Javid, B.1
Sorrentino, F.2
Toosky, M.3
Zheng, W.4
Pinkham, J.T.5
Jain, N.6
Pan, M.7
Deighan, F.8
Rubin, E.J.9
-
57
-
-
84920880232
-
Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms
-
G. Manina, N. Dhar, J. D. McKinney, Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms. Cell Host Microbe 17, 32-46 (2015).
-
(2015)
Cell Host Microbe
, vol.17
, pp. 32-46
-
-
Manina, G.1
Dhar, N.2
McKinney, J.D.3
-
58
-
-
66249136447
-
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
-
S. L. Spencer, S. Gaudet, J. G. Albeck, J. M. Burke, P. K. Sorger, Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 459, 428-432 (2009).
-
(2009)
Nature
, vol.459
, pp. 428-432
-
-
Spencer, S.L.1
Gaudet, S.2
Albeck, J.G.3
Burke, J.M.4
Sorger, P.K.5
-
59
-
-
33745189789
-
Non-inherited antibiotic resistance
-
B. R. Levin, D. E. Rozen, Non-inherited antibiotic resistance. Nat. Rev. Microbiol. 4, 556-562 (2006).
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 556-562
-
-
Levin, B.R.1
Rozen, D.E.2
-
62
-
-
33846814925
-
Intracellular growth and drug susceptibility of Mycobacterium tuberculosis in macrophages
-
S. Chanwong, N. Maneekarn, L. Makonkawkeyoon, S. Makonkawkeyoon, Intracellular growth and drug susceptibility of Mycobacterium tuberculosis in macrophages. Tuberculosis 87, 130-133 (2007).
-
(2007)
Tuberculosis
, vol.87
, pp. 130-133
-
-
Chanwong, S.1
Maneekarn, N.2
Makonkawkeyoon, L.3
Makonkawkeyoon, S.4
-
63
-
-
77956197501
-
Isonicotinic acid hydrazide conversion to isonicotinyl-NAD by catalase-peroxidases
-
B. Wiseman, X. Carpena, M. Feliz, L. J. Donald, M. Pons, I. Fita, P. C. Loewen, Isonicotinic acid hydrazide conversion to isonicotinyl-NAD by catalase-peroxidases. J. Biol. Chem. 285, 26662-26673 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 26662-26673
-
-
Wiseman, B.1
Carpena, X.2
Feliz, M.3
Donald, L.J.4
Pons, M.5
Fita, I.6
Loewen, P.C.7
-
64
-
-
18344417541
-
Use of flow field-flow fractionation for the rapid quantitation of ribosome and ribosomal subunits in Escherichia coli at different protein production conditions
-
M. Nilsson, L. Bülow, K. G. Wahlund, Use of flow field-flow fractionation for the rapid quantitation of ribosome and ribosomal subunits in Escherichia coli at different protein production conditions. Biotechnol. Bioeng. 54, 461-467 (1997).
-
(1997)
Biotechnol. Bioeng.
, vol.54
, pp. 461-467
-
-
Nilsson, M.1
Bülow, L.2
Wahlund, K.G.3
-
65
-
-
0000640710
-
-
F. C. Neidhardt, Ed. American Society for Microbiology, Washington, DC
-
H. Bremer, P. P. Dennis, in In Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology, F. C. Neidhardt, Ed. (American Society for Microbiology, Washington, DC, 1987), pp. 1553-1569.
-
(1987)
In Escherichia Coli and Salmonella Typhimurium: Cellular and Molecular Biology
, pp. 1553-1569
-
-
Bremer, H.1
Dennis, P.P.2
-
66
-
-
0021298678
-
The binding of 6-demethylchlortetracycline to 70S, 50S and 30S ribosomal particles: A quantitative study by fluorescence anisotropy
-
B. Epe, P. Woolley, The binding of 6-demethylchlortetracycline to 70S, 50S and 30S ribosomal particles: A quantitative study by fluorescence anisotropy. EMBO J. 3, 121-126 (1984).
-
(1984)
EMBO J.
, vol.3
, pp. 121-126
-
-
Epe, B.1
Woolley, P.2
-
67
-
-
42149157706
-
Chemical biology of tetracycline antibiotics
-
B. Zakeri, G. D. Wright, Chemical biology of tetracycline antibiotics. Biochem. Cell Biol. 86, 124-136 (2008).
-
(2008)
Biochem. Cell Biol.
, vol.86
, pp. 124-136
-
-
Zakeri, B.1
Wright, G.D.2
-
68
-
-
17744377418
-
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
-
M. Pioletti, F. Schlünzen, J. Harms, R. Zarivach, M. Glühmann, H. Avila, A. Bashan, H. Bartels, T. Auerbach, C. Jacobi, T. Hartsch, A. Yonath, F. Franceschi, Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J. 20, 1829-1839 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 1829-1839
-
-
Pioletti, M.1
Schlünzen, F.2
Harms, J.3
Zarivach, R.4
Glühmann, M.5
Avila, H.6
Bashan, A.7
Bartels, H.8
Auerbach, T.9
Jacobi, C.10
Hartsch, T.11
Yonath, A.12
Franceschi, F.13
-
69
-
-
0017671181
-
Ribosome-tetracycline interactions
-
T. R. Tritton, Ribosome-tetracycline interactions. Biochemistry 16, 4133-4138 (1977).
-
(1977)
Biochemistry
, vol.16
, pp. 4133-4138
-
-
Tritton, T.R.1
-
70
-
-
0021992123
-
Mechanism of action of gentamicin components. Characteristics of their binding to Escherichia coli ribosomes
-
F. Tangy, M. Moukkadem, E. Vindimian, M. L. Capmau, F. Le Goffic, Mechanism of action of gentamicin components. Characteristics of their binding to Escherichia coli ribosomes. Eur. J. Biochem. 147, 381-386 (1985).
-
(1985)
Eur. J. Biochem.
, vol.147
, pp. 381-386
-
-
Tangy, F.1
Moukkadem, M.2
Vindimian, E.3
Capmau, M.L.4
Le Goffic, F.5
-
71
-
-
67651002917
-
Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding
-
B. Llano-Sotelo, R. P. Hickerson, L. Lancaster, H. F. Noller, A. S. Mankin, Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding. RNA 15, 1597-1604 (2009).
-
(2009)
RNA
, vol.15
, pp. 1597-1604
-
-
Llano-Sotelo, B.1
Hickerson, R.P.2
Lancaster, L.3
Noller, H.F.4
Mankin, A.S.5
-
72
-
-
0015417692
-
Binding of dihydrostreptomycin to Escherichia coli ribosomes: Kinetics of the reaction
-
F. N. Chang, J. G. Flaks, Binding of dihydrostreptomycin to Escherichia coli ribosomes: Kinetics of the reaction. Antimicrob. Agents Chemother. 2, 308-319 (1972).
-
(1972)
Antimicrob. Agents Chemother.
, vol.2
, pp. 308-319
-
-
Chang, F.N.1
Flaks, J.G.2
-
73
-
-
0017188238
-
Paromomycin and dihydrostreptomycin binding to Escherichia coli ribosomes
-
D. Lando, M. A. Cousin, T. Ojasoo, J. P. Raymond, Paromomycin and dihydrostreptomycin binding to Escherichia coli ribosomes. Eur. J. Biochem. 66, 597-606 (1976).
-
(1976)
Eur. J. Biochem.
, vol.66
, pp. 597-606
-
-
Lando, D.1
Cousin, M.A.2
Ojasoo, T.3
Raymond, J.P.4
-
74
-
-
0013096299
-
Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12
-
B. G. Spratt, Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. Proc. Natl. Acad. Sci. U. S. A. 72, 2999-3003 (1975).
-
(1975)
Proc. Natl. Acad. Sci. U. S. A.
, vol.72
, pp. 2999-3003
-
-
Spratt, B.G.1
-
75
-
-
0032874101
-
The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli
-
M. Terrak, T. K. Ghosh, J. Van Heijenoort, J. Van Beeumen, M. Lampilas, J. Aszodi, J. A. Ayala, J. M. Ghuysen, M. Nguyen-Distèche, The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli. Mol. Microbiol. 34, 350-364 (1999).
-
(1999)
Mol. Microbiol.
, vol.34
, pp. 350-364
-
-
Terrak, M.1
Ghosh, T.K.2
Van Heijenoort, J.3
Van Beeumen, J.4
Lampilas, M.5
Aszodi, J.6
Ayala, J.A.7
Ghuysen, J.M.8
Nguyen-Distèche, M.9
-
76
-
-
79960578471
-
Quantification of mRNA and protein and integration with protein turnover in a bacterium
-
T. Maier, A. Schmidt, M. Güell, S. Kühner, A. C. Gavin, R. Aebersold, L. Serrano, Quantification of mRNA and protein and integration with protein turnover in a bacterium. Mol. Syst. Biol. 7, 511 (2011).
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 511
-
-
Maier, T.1
Schmidt, A.2
Güell, M.3
Kühner, S.4
Gavin, A.C.5
Aebersold, R.6
Serrano, L.7
-
77
-
-
68449102172
-
Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans
-
J. Malmström, M. Beck, A. Schmidt, V. Lange, E. W. Deutsch, R. Aebersold, Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature 460, 762-765 (2009).
-
(2009)
Nature
, vol.460
, pp. 762-765
-
-
Malmström, J.1
Beck, M.2
Schmidt, A.3
Lange, V.4
Deutsch, E.W.5
Aebersold, R.6
-
78
-
-
0017663729
-
Kinetic studies of the interaction between rifampicin and DNA-dependent RNA polymerase of Escherichia coli
-
W. Wehrli, Kinetic studies of the interaction between rifampicin and DNA-dependent RNA polymerase of Escherichia coli. Eur. J. Biochem. 80, 325-330 (1977).
-
(1977)
Eur. J. Biochem.
, vol.80
, pp. 325-330
-
-
Wehrli, W.1
-
79
-
-
68049100110
-
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
-
B. D. Bennett, E. H. Kimball, M. Gao, R. Osterhout, S. J. Van Dien, J. D. Rabinowitz, Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nat. Chem. Biol. 5, 593-599 (2009).
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 593-599
-
-
Bennett, B.D.1
Kimball, E.H.2
Gao, M.3
Osterhout, R.4
Van Dien, S.J.5
Rabinowitz, J.D.6
-
80
-
-
77955102352
-
Quantifying E.coli proteome and transcriptome with single-molecule sensitivity in single cells
-
Y. Taniguchi, P. J. Choi, G. W. Li, H. Chen, M. Babu, J. Hearn, A. Emili, X. S. Xie, Quantifying E.coli proteome and transcriptome with single-molecule sensitivity in single cells. Science 329, 533-538 (2010).
-
(2010)
Science
, vol.329
, pp. 533-538
-
-
Taniguchi, Y.1
Choi, P.J.2
Li, G.W.3
Chen, H.4
Babu, M.5
Hearn, J.6
Emili, A.7
Xie, X.S.8
-
81
-
-
0033520469
-
Spontaneous formation of the bioactive form of the tuberculosis drug isoniazid
-
M. Wilming, K. Johnsson, Spontaneous formation of the bioactive form of the tuberculosis drug isoniazid. Angew. Chem. Int. Ed. Engl. 38, 2588-2590 (1999).
-
(1999)
Angew. Chem. Int. Ed. Engl.
, vol.38
, pp. 2588-2590
-
-
Wilming, M.1
Johnsson, K.2
-
82
-
-
0345133299
-
The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: Adduct affinity and drug resistance
-
R. Rawat, A. Whitty, P. J. Tonge, The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: Adduct affinity and drug resistance. Proc. Natl. Acad. Sci. U. S. A. 100, 13881-13886 (2003).
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13881-13886
-
-
Rawat, R.1
Whitty, A.2
Tonge, P.J.3
|