메뉴 건너뛰기




Volumn 157, Issue 3, 2014, Pages 539-548

Molecular mechanisms underlying bacterial persisters

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC RESISTANCE; BACTERIAL CELL; BACTERIAL GENE; MICROFLUIDIC ANALYSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REPORTER GENE; REVIEW;

EID: 84899505083     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.02.050     Document Type: Review
Times cited : (509)

References (100)
  • 1
    • 0000123301 scopus 로고
    • An Enzyme from Bacteria able to Destroy Penicillin
    • E.P. Abraham, and E. Chain An Enzyme from Bacteria able to Destroy Penicillin Nature 146 1940 837
    • (1940) Nature , vol.146 , pp. 837
    • Abraham, E.P.1    Chain, E.2
  • 2
    • 0034939217 scopus 로고    scopus 로고
    • The ratio between CcdA and CcdB modulates the transcriptional repression of the ccd poison-antidote system
    • H. Afif, N. Allali, M. Couturier, and L. Van Melderen The ratio between CcdA and CcdB modulates the transcriptional repression of the ccd poison-antidote system Mol. Microbiol. 41 2001 73 82
    • (2001) Mol. Microbiol. , vol.41 , pp. 73-82
    • Afif, H.1    Allali, N.2    Couturier, M.3    Van Melderen, L.4
  • 4
    • 79955886933 scopus 로고    scopus 로고
    • Metabolite-enabled eradication of bacterial persisters by aminoglycosides
    • K.R. Allison, M.P. Brynildsen, and J.J. Collins Metabolite-enabled eradication of bacterial persisters by aminoglycosides Nature 473 2011 216 220
    • (2011) Nature , vol.473 , pp. 216-220
    • Allison, K.R.1    Brynildsen, M.P.2    Collins, J.J.3
  • 5
    • 84878204775 scopus 로고    scopus 로고
    • Metabolic control of persister formation in Escherichia coli
    • S.M. Amato, M.A. Orman, and M.P. Brynildsen Metabolic control of persister formation in Escherichia coli Mol. Cell 50 2013 475 487
    • (2013) Mol. Cell , vol.50 , pp. 475-487
    • Amato, S.M.1    Orman, M.A.2    Brynildsen, M.P.3
  • 7
    • 33646032683 scopus 로고    scopus 로고
    • Bacterially speaking
    • B.L. Bassler, and R. Losick Bacterially speaking Cell 125 2006 237 246
    • (2006) Cell , vol.125 , pp. 237-246
    • Bassler, B.L.1    Losick, R.2
  • 8
    • 0345827436 scopus 로고    scopus 로고
    • SOS response promotes horizontal dissemination of antibiotic resistance genes
    • J.W. Beaber, B. Hochhut, and M.K. Waldor SOS response promotes horizontal dissemination of antibiotic resistance genes Nature 427 2004 72 74
    • (2004) Nature , vol.427 , pp. 72-74
    • Beaber, J.W.1    Hochhut, B.2    Waldor, M.K.3
  • 9
    • 0026728290 scopus 로고
    • Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes
    • P. Bernard, and M. Couturier Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes J. Mol. Biol. 226 1992 735 745
    • (1992) J. Mol. Biol. , vol.226 , pp. 735-745
    • Bernard, P.1    Couturier, M.2
  • 11
    • 50349141358 scopus 로고
    • Treatment of staphyloccal infections with penicillin by intermittent sterilisation
    • J.W. Bigger Treatment of staphyloccal infections with penicillin by intermittent sterilisation Lancet ii 1944 497 500
    • (1944) Lancet , vol.II , pp. 497-500
    • Bigger, J.W.1
  • 12
    • 0025940779 scopus 로고
    • Structure and organization of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis
    • D.S. Black, A.J. Kelly, M.J. Mardis, and H.S. Moyed Structure and organization of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis J. Bacteriol. 173 1991 5732 5739
    • (1991) J. Bacteriol. , vol.173 , pp. 5732-5739
    • Black, D.S.1    Kelly, A.J.2    Mardis, M.J.3    Moyed, H.S.4
  • 13
    • 0028270774 scopus 로고
    • Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis
    • D.S. Black, B. Irwin, and H.S. Moyed Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis J. Bacteriol. 176 1994 4081 4091
    • (1994) J. Bacteriol. , vol.176 , pp. 4081-4091
    • Black, D.S.1    Irwin, B.2    Moyed, H.S.3
  • 16
    • 84864950352 scopus 로고    scopus 로고
    • Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery
    • I. Cataudella, A. Trusina, K. Sneppen, K. Gerdes, and N. Mitarai Conditional cooperativity in toxin-antitoxin regulation prevents random toxin activation and promotes fast translational recovery Nucleic Acids Res. 40 2012 6424 6434
    • (2012) Nucleic Acids Res. , vol.40 , pp. 6424-6434
    • Cataudella, I.1    Trusina, A.2    Sneppen, K.3    Gerdes, K.4    Mitarai, N.5
  • 17
    • 84883401486 scopus 로고    scopus 로고
    • Conditional cooperativity of toxin - Antitoxin regulation can mediate bistability between growth and dormancy
    • I. Cataudella, K. Sneppen, K. Gerdes, and N. Mitarai Conditional cooperativity of toxin - antitoxin regulation can mediate bistability between growth and dormancy PLoS Comput. Biol. 9 2013 e1003174
    • (2013) PLoS Comput. Biol. , vol.9 , pp. 1003174
    • Cataudella, I.1    Sneppen, K.2    Gerdes, K.3    Mitarai, N.4
  • 18
    • 0038797797 scopus 로고    scopus 로고
    • RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA
    • S.K. Christensen, and K. Gerdes RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA Mol. Microbiol. 48 2003 1389 1400
    • (2003) Mol. Microbiol. , vol.48 , pp. 1389-1400
    • Christensen, S.K.1    Gerdes, K.2
  • 19
    • 33749178742 scopus 로고    scopus 로고
    • Two higBA loci in the Vibrio cholerae superintegron encode mRNA cleaving enzymes and can stabilize plasmids
    • M. Christensen-Dalsgaard, and K. Gerdes Two higBA loci in the Vibrio cholerae superintegron encode mRNA cleaving enzymes and can stabilize plasmids Mol. Microbiol. 62 2006 397 411
    • (2006) Mol. Microbiol. , vol.62 , pp. 397-411
    • Christensen-Dalsgaard, M.1    Gerdes, K.2
  • 20
    • 74349123303 scopus 로고    scopus 로고
    • Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses
    • M. Christensen-Dalsgaard, M.G. Jørgensen, and K. Gerdes Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses Mol. Microbiol. 75 2010 333 348
    • (2010) Mol. Microbiol. , vol.75 , pp. 333-348
    • Christensen-Dalsgaard, M.1    Jørgensen, M.G.2    Gerdes, K.3
  • 22
    • 33845428404 scopus 로고    scopus 로고
    • Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli
    • F.F. Correia, A. D'Onofrio, T. Rejtar, L. Li, B.L. Karger, K. Makarova, E.V. Koonin, and K. Lewis Kinase activity of overexpressed HipA is required for growth arrest and multidrug tolerance in Escherichia coli J. Bacteriol. 188 2006 8360 8367
    • (2006) J. Bacteriol. , vol.188 , pp. 8360-8367
    • Correia, F.F.1    D'Onofrio, A.2    Rejtar, T.3    Li, L.4    Karger, B.L.5    Makarova, K.6    Koonin, E.V.7    Lewis, K.8
  • 24
    • 84875802555 scopus 로고    scopus 로고
    • Salmonella enterica: A surprisingly well-adapted intracellular lifestyle
    • T. Dandekar, F. Astrid, P. Jasmin, and M. Hensel Salmonella enterica: a surprisingly well-adapted intracellular lifestyle Frontiers in microbiology 3 2012 164
    • (2012) Frontiers in Microbiology , vol.3 , pp. 164
    • Dandekar, T.1    Astrid, F.2    Jasmin, P.3    Hensel, M.4
  • 25
    • 33846796149 scopus 로고    scopus 로고
    • Microbial phenotypic heterogeneity and antibiotic tolerance
    • N. Dhar, and J.D. McKinney Microbial phenotypic heterogeneity and antibiotic tolerance Curr. Opin. Microbiol. 10 2007 30 38
    • (2007) Curr. Opin. Microbiol. , vol.10 , pp. 30-38
    • Dhar, N.1    McKinney, J.D.2
  • 26
    • 74249107300 scopus 로고    scopus 로고
    • SOS response induces persistence to fluoroquinolones in Escherichia coli
    • T. Dörr, K. Lewis, and M. Vulić SOS response induces persistence to fluoroquinolones in Escherichia coli PLoS Genet. 5 2009 e1000760
    • (2009) PLoS Genet. , vol.5 , pp. 1000760
    • Dörr, T.1    Lewis, K.2    Vulić, M.3
  • 27
    • 77649174212 scopus 로고    scopus 로고
    • Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli
    • T. Dörr, M. Vulić, and K. Lewis Ciprofloxacin causes persister formation by inducing the TisB toxin in Escherichia coli PLoS Biol. 8 2010 e1000317
    • (2010) PLoS Biol. , vol.8 , pp. 1000317
    • Dörr, T.1    Vulić, M.2    Lewis, K.3
  • 28
    • 33748058888 scopus 로고    scopus 로고
    • Bistability in bacteria
    • D. Dubnau, and R. Losick Bistability in bacteria Mol. Microbiol. 61 2006 564 572
    • (2006) Mol. Microbiol. , vol.61 , pp. 564-572
    • Dubnau, D.1    Losick, R.2
  • 29
    • 38649092391 scopus 로고    scopus 로고
    • Transcription profiling of the stringent response in Escherichia coli
    • T. Durfee, A.M. Hansen, H. Zhi, F.R. Blattner, and D.J. Jin Transcription profiling of the stringent response in Escherichia coli J. Bacteriol. 190 2008 1084 1096
    • (2008) J. Bacteriol. , vol.190 , pp. 1084-1096
    • Durfee, T.1    Hansen, A.M.2    Zhi, H.3    Blattner, F.R.4    Jin, D.J.5
  • 30
    • 77956520011 scopus 로고    scopus 로고
    • Functional roles for noise in genetic circuits
    • A. Eldar, and M.B. Elowitz Functional roles for noise in genetic circuits Nature 467 2010 167 173
    • (2010) Nature , vol.467 , pp. 167-173
    • Eldar, A.1    Elowitz, M.B.2
  • 33
    • 0031788934 scopus 로고    scopus 로고
    • Joint tolerance to beta-lactam and fluoroquinolone antibiotics in Escherichia coli results from overexpression of hipA
    • T.J. Falla, and I. Chopra Joint tolerance to beta-lactam and fluoroquinolone antibiotics in Escherichia coli results from overexpression of hipA Antimicrob. Agents Chemother. 42 1998 3282 3284
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 3282-3284
    • Falla, T.J.1    Chopra, I.2
  • 34
    • 84879728880 scopus 로고    scopus 로고
    • Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype
    • R.A. Fasani, and M.A. Savageau Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype Proc. Natl. Acad. Sci. USA 110 2013 E2528 E2537
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110
    • Fasani, R.A.1    Savageau, M.A.2
  • 35
    • 77149145486 scopus 로고    scopus 로고
    • Delineation of a bacterial starvation stress response network which can mediate antibiotic tolerance development
    • D.K. Fung, E.W. Chan, M.L. Chin, and R.C. Chan Delineation of a bacterial starvation stress response network which can mediate antibiotic tolerance development Antimicrob. Agents Chemother. 54 2010 1082 1093
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 1082-1093
    • Fung, D.K.1    Chan, E.W.2    Chin, M.L.3    Chan, R.C.4
  • 36
    • 84887198561 scopus 로고    scopus 로고
    • Basal levels of (p)ppGpp in Enterococcus faecalis: The magic beyond the stringent response
    • A.O. Gaca, J.K. Kajfasz, J.H. Miller, K. Liu, J.D. Wang, J. Abranches, and J.A. Lemos Basal levels of (p)ppGpp in Enterococcus faecalis: the magic beyond the stringent response mBiol. 4 2013 e00646-00613
    • (2013) MBiol. , vol.4
    • Gaca, A.O.1    Kajfasz, J.K.2    Miller, J.H.3    Liu, K.4    Wang, J.D.5    Abranches, J.6    Lemos, J.A.7
  • 38
    • 84892966765 scopus 로고    scopus 로고
    • Two small (p)ppGpp synthases in Staphylococcus aureus mediate tolerance against cell envelope stress conditions
    • T. Geiger, B. Kästle, F.L. Gratani, C. Goerke, and C. Wolz Two small (p)ppGpp synthases in Staphylococcus aureus mediate tolerance against cell envelope stress conditions J. Bacteriol. 196 2014 894 902
    • (2014) J. Bacteriol. , vol.196 , pp. 894-902
    • Geiger, T.1    Kästle, B.2    Gratani, F.L.3    Goerke, C.4    Wolz, C.5
  • 39
    • 84883350971 scopus 로고    scopus 로고
    • A general model for toxin-antitoxin module dynamics can explain persister cell formation in E coli
    • L. Gelens, L. Hill, A. Vandervelde, J. Danckaert, and R. Loris A general model for toxin-antitoxin module dynamics can explain persister cell formation in E coli PLoS Comput. Biol. 9 2013 e1003190
    • (2013) PLoS Comput. Biol. , vol.9 , pp. 1003190
    • Gelens, L.1    Hill, L.2    Vandervelde, A.3    Danckaert, J.4    Loris, R.5
  • 40
    • 84872241785 scopus 로고    scopus 로고
    • Bacterial persistence and toxin-antitoxin loci
    • K. Gerdes, and E. Maisonneuve Bacterial persistence and toxin-antitoxin loci Annu. Rev. Microbiol. 66 2012 103 123
    • (2012) Annu. Rev. Microbiol. , vol.66 , pp. 103-123
    • Gerdes, K.1    Maisonneuve, E.2
  • 41
    • 84886290812 scopus 로고    scopus 로고
    • Molecular mechanism of bacterial persistence by HipA
    • E. Germain, D. Castro-Roa, N. Zenkin, and K. Gerdes Molecular mechanism of bacterial persistence by HipA Mol. Cell 52 2013 248 254
    • (2013) Mol. Cell , vol.52 , pp. 248-254
    • Germain, E.1    Castro-Roa, D.2    Zenkin, N.3    Gerdes, K.4
  • 42
    • 48749089081 scopus 로고    scopus 로고
    • Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli
    • S. Hansen, K. Lewis, and M. Vulić Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli Antimicrob. Agents Chemother. 52 2008 2718 2726
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 2718-2726
    • Hansen, S.1    Lewis, K.2    Vulić, M.3
  • 46
    • 84892181925 scopus 로고    scopus 로고
    • Internalization of Salmonella by macrophages induces formation of nonreplicating persisters
    • S. Helaine, A.M. Cheverton, K.G. Watson, L.M. Faure, S.A. Matthews, and D.W. Holden Internalization of Salmonella by macrophages induces formation of nonreplicating persisters Science 343 2014 204 208
    • (2014) Science , vol.343 , pp. 204-208
    • Helaine, S.1    Cheverton, A.M.2    Watson, K.G.3    Faure, L.M.4    Matthews, S.A.5    Holden, D.W.6
  • 47
    • 0036098378 scopus 로고    scopus 로고
    • ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase
    • Y. Jiang, J. Pogliano, D.R. Helinski, and I. Konieczny ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase Mol. Microbiol. 44 2002 971 979
    • (2002) Mol. Microbiol. , vol.44 , pp. 971-979
    • Jiang, Y.1    Pogliano, J.2    Helinski, D.R.3    Konieczny, I.4
  • 48
    • 60849121408 scopus 로고    scopus 로고
    • HicA of Escherichia coli defines a novel family of translation- independent mRNA interferases in bacteria and archaea
    • M.G. Jørgensen, D.P. Pandey, M. Jaskolska, and K. Gerdes HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea J. Bacteriol. 191 2009 1191 1199
    • (2009) J. Bacteriol. , vol.191 , pp. 1191-1199
    • Jørgensen, M.G.1    Pandey, D.P.2    Jaskolska, M.3    Gerdes, K.4
  • 49
    • 84890639139 scopus 로고    scopus 로고
    • HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase
    • I. Kaspy, E. Rotem, N. Weiss, I. Ronin, N.Q. Balaban, and G. Glaser HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase Nature communications 4 2013 3001
    • (2013) Nature Communications , vol.4 , pp. 3001
    • Kaspy, I.1    Rotem, E.2    Weiss, N.3    Ronin, I.4    Balaban, N.Q.5    Glaser, G.6
  • 51
    • 10044266575 scopus 로고    scopus 로고
    • Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
    • I. Keren, D. Shah, A. Spoering, N. Kaldalu, and K. Lewis Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli J. Bacteriol. 186 2004 8172 8180
    • (2004) J. Bacteriol. , vol.186 , pp. 8172-8180
    • Keren, I.1    Shah, D.2    Spoering, A.3    Kaldalu, N.4    Lewis, K.5
  • 52
    • 84874720377 scopus 로고    scopus 로고
    • Killing by bactericidal antibiotics does not depend on reactive oxygen species
    • I. Keren, Y. Wu, J. Inocencio, L.R. Mulcahy, and K. Lewis Killing by bactericidal antibiotics does not depend on reactive oxygen species Science 339 2013 1213 1216
    • (2013) Science , vol.339 , pp. 1213-1216
    • Keren, I.1    Wu, Y.2    Inocencio, J.3    Mulcahy, L.R.4    Lewis, K.5
  • 53
    • 72949116993 scopus 로고    scopus 로고
    • Toxins Hha and CspD and small RNA regulator Hfq are involved in persister cell formation through MqsR in Escherichia coli
    • Y. Kim, and T.K. Wood Toxins Hha and CspD and small RNA regulator Hfq are involved in persister cell formation through MqsR in Escherichia coli Biochem. Biophys. Res. Commun. 391 2010 209 213
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , pp. 209-213
    • Kim, Y.1    Wood, T.K.2
  • 55
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • M.A. Kohanski, D.J. Dwyer, B. Hayete, C.A. Lawrence, and J.J. Collins A common mechanism of cellular death induced by bactericidal antibiotics Cell 130 2007 797 810
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1    Dwyer, D.J.2    Hayete, B.3    Lawrence, C.A.4    Collins, J.J.5
  • 56
    • 55449126342 scopus 로고    scopus 로고
    • Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death
    • M.A. Kohanski, D.J. Dwyer, J. Wierzbowski, G. Cottarel, and J.J. Collins Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death Cell 135 2008 679 690
    • (2008) Cell , vol.135 , pp. 679-690
    • Kohanski, M.A.1    Dwyer, D.J.2    Wierzbowski, J.3    Cottarel, G.4    Collins, J.J.5
  • 57
    • 33744729683 scopus 로고    scopus 로고
    • Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: Effects on macromolecular synthesis and persister formation
    • S.B. Korch, and T.M. Hill Ectopic overexpression of wild-type and mutant hipA genes in Escherichia coli: effects on macromolecular synthesis and persister formation J. Bacteriol. 188 2006 3826 3836
    • (2006) J. Bacteriol. , vol.188 , pp. 3826-3836
    • Korch, S.B.1    Hill, T.M.2
  • 58
    • 0344826574 scopus 로고    scopus 로고
    • Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis
    • S.B. Korch, T.A. Henderson, and T.M. Hill Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis Mol. Microbiol. 50 2003 1199 1213
    • (2003) Mol. Microbiol. , vol.50 , pp. 1199-1213
    • Korch, S.B.1    Henderson, T.A.2    Hill, T.M.3
  • 59
    • 25444489027 scopus 로고    scopus 로고
    • Phenotypic diversity, population growth, and information in fluctuating environments
    • E. Kussell, and S. Leibler Phenotypic diversity, population growth, and information in fluctuating environments Science 309 2005 2075 2078
    • (2005) Science , vol.309 , pp. 2075-2078
    • Kussell, E.1    Leibler, S.2
  • 60
    • 73849102829 scopus 로고    scopus 로고
    • Patients with long-term oral carriage harbor high-persister mutants of Candida albicans
    • M.D. Lafleur, Q. Qi, and K. Lewis Patients with long-term oral carriage harbor high-persister mutants of Candida albicans Antimicrob. Agents Chemother. 54 2010 39 44
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 39-44
    • Lafleur, M.D.1    Qi, Q.2    Lewis, K.3
  • 61
    • 84861206553 scopus 로고    scopus 로고
    • A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance
    • V. Leung, and C.M. Lévesque A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance J. Bacteriol. 194 2012 2265 2274
    • (2012) J. Bacteriol. , vol.194 , pp. 2265-2274
    • Leung, V.1    Lévesque, C.M.2
  • 62
    • 33745189789 scopus 로고    scopus 로고
    • Non-inherited antibiotic resistance
    • B.R. Levin, and D.E. Rozen Non-inherited antibiotic resistance Nat. Rev. Microbiol. 4 2006 556 562
    • (2006) Nat. Rev. Microbiol. , vol.4 , pp. 556-562
    • Levin, B.R.1    Rozen, D.E.2
  • 64
    • 84874695302 scopus 로고    scopus 로고
    • Cell death from antibiotics without the involvement of reactive oxygen species
    • Y. Liu, and J.A. Imlay Cell death from antibiotics without the involvement of reactive oxygen species Science 339 2013 1210 1213
    • (2013) Science , vol.339 , pp. 1210-1213
    • Liu, Y.1    Imlay, J.A.2
  • 65
    • 54249117139 scopus 로고    scopus 로고
    • A molecular model for persister in E coli
    • C. Lou, Z. Li, and Q. Ouyang A molecular model for persister in E coli J. Theor. Biol. 255 2008 205 209
    • (2008) J. Theor. Biol. , vol.255 , pp. 205-209
    • Lou, C.1    Li, Z.2    Ouyang, Q.3
  • 66
    • 84876187408 scopus 로고    scopus 로고
    • The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics
    • T.F. Mahoney, and T.J. Silhavy The Cpx stress response confers resistance to some, but not all, bactericidal antibiotics J. Bacteriol. 195 2013 1869 1874
    • (2013) J. Bacteriol. , vol.195 , pp. 1869-1874
    • Mahoney, T.F.1    Silhavy, T.J.2
  • 68
    • 84883342218 scopus 로고    scopus 로고
    • (p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity
    • E. Maisonneuve, M. Castro-Camargo, and K. Gerdes (p)ppGpp controls bacterial persistence by stochastic induction of toxin-antitoxin activity Cell 154 2013 1140 1150
    • (2013) Cell , vol.154 , pp. 1140-1150
    • Maisonneuve, E.1    Castro-Camargo, M.2    Gerdes, K.3
  • 69
    • 84861347512 scopus 로고    scopus 로고
    • YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli
    • H. Masuda, Q. Tan, N. Awano, K.P. Wu, and M. Inouye YeeU enhances the bundling of cytoskeletal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli Mol. Microbiol. 84 2012 979 989
    • (2012) Mol. Microbiol. , vol.84 , pp. 979-989
    • Masuda, H.1    Tan, Q.2    Awano, N.3    Wu, K.P.4    Inouye, M.5
  • 70
    • 77949677963 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum-sensing signaling molecules
    • N. Möker, C.R. Dean, and J. Tao Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum-sensing signaling molecules J. Bacteriol. 192 2010 1946 1955
    • (2010) J. Bacteriol. , vol.192 , pp. 1946-1955
    • Möker, N.1    Dean, C.R.2    Tao, J.3
  • 72
    • 0020590028 scopus 로고
    • HipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
    • H.S. Moyed, and K.P. Bertrand hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis J. Bacteriol. 155 1983 768 775
    • (1983) J. Bacteriol. , vol.155 , pp. 768-775
    • Moyed, H.S.1    Bertrand, K.P.2
  • 73
    • 0022591020 scopus 로고
    • Molecular cloning and expression of hipA, a gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
    • H.S. Moyed, and S.H. Broderick Molecular cloning and expression of hipA, a gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis J. Bacteriol. 166 1986 399 403
    • (1986) J. Bacteriol. , vol.166 , pp. 399-403
    • Moyed, H.S.1    Broderick, S.H.2
  • 74
    • 77957947243 scopus 로고    scopus 로고
    • Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis
    • L.R. Mulcahy, J.L. Burns, S. Lory, and K. Lewis Emergence of Pseudomonas aeruginosa strains producing high levels of persister cells in patients with cystic fibrosis J. Bacteriol. 192 2010 6191 6199
    • (2010) J. Bacteriol. , vol.192 , pp. 6191-6199
    • Mulcahy, L.R.1    Burns, J.L.2    Lory, S.3    Lewis, K.4
  • 76
    • 0037385854 scopus 로고    scopus 로고
    • Conditional senescence in bacteria: Death of the immortals
    • T. Nyström Conditional senescence in bacteria: death of the immortals Mol. Microbiol. 48 2003 17 23
    • (2003) Mol. Microbiol. , vol.48 , pp. 17-23
    • Nyström, T.1
  • 77
    • 47749089764 scopus 로고    scopus 로고
    • Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity
    • M. Overgaard, J. Borch, M.G. Jørgensen, and K. Gerdes Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity Mol. Microbiol. 69 2008 841 857
    • (2008) Mol. Microbiol. , vol.69 , pp. 841-857
    • Overgaard, M.1    Borch, J.2    Jørgensen, M.G.3    Gerdes, K.4
  • 78
    • 70350552019 scopus 로고    scopus 로고
    • RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB
    • M. Overgaard, J. Borch, and K. Gerdes RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB J. Mol. Biol. 394 2009 183 196
    • (2009) J. Mol. Biol. , vol.394 , pp. 183-196
    • Overgaard, M.1    Borch, J.2    Gerdes, K.3
  • 79
    • 0036067108 scopus 로고    scopus 로고
    • Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins
    • K. Pedersen, S.K. Christensen, and K. Gerdes Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins Mol. Microbiol. 45 2002 501 510
    • (2002) Mol. Microbiol. , vol.45 , pp. 501-510
    • Pedersen, K.1    Christensen, S.K.2    Gerdes, K.3
  • 81
    • 58449087611 scopus 로고    scopus 로고
    • Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB
    • M.A. Schumacher, K.M. Piro, W. Xu, S. Hansen, K. Lewis, and R.G. Brennan Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB Science 323 2009 396 401
    • (2009) Science , vol.323 , pp. 396-401
    • Schumacher, M.A.1    Piro, K.M.2    Xu, W.3    Hansen, S.4    Lewis, K.5    Brennan, R.G.6
  • 84
    • 81555205640 scopus 로고    scopus 로고
    • H2S: A universal defense against antibiotics in bacteria
    • K. Shatalin, E. Shatalina, A. Mironov, and E. Nudler H2S: a universal defense against antibiotics in bacteria Science 334 2011 986 990
    • (2011) Science , vol.334 , pp. 986-990
    • Shatalin, K.1    Shatalina, E.2    Mironov, A.3    Nudler, E.4
  • 87
    • 51649129121 scopus 로고    scopus 로고
    • A small SOS-induced toxin is targeted against the inner membrane in Escherichia coli
    • C. Unoson, and E.G. Wagner A small SOS-induced toxin is targeted against the inner membrane in Escherichia coli Mol. Microbiol. 70 2008 258 270
    • (2008) Mol. Microbiol. , vol.70 , pp. 258-270
    • Unoson, C.1    Wagner, E.G.2
  • 88
    • 33646549559 scopus 로고    scopus 로고
    • Increased persistence in Escherichia coli caused by controlled expression of toxins or other unrelated proteins
    • N. Vázquez-Laslop, H. Lee, and A.A. Neyfakh Increased persistence in Escherichia coli caused by controlled expression of toxins or other unrelated proteins J. Bacteriol. 188 2006 3494 3497
    • (2006) J. Bacteriol. , vol.188 , pp. 3494-3497
    • Vázquez-Laslop, N.1    Lee, H.2    Neyfakh, A.A.3
  • 89
  • 91
  • 95
    • 79956328889 scopus 로고    scopus 로고
    • Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA
    • K.S. Winther, and K. Gerdes Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA Proc. Natl. Acad. Sci. USA 108 2011 7403 7407
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 7403-7407
    • Winther, K.S.1    Gerdes, K.2
  • 96
    • 84861550633 scopus 로고    scopus 로고
    • Regulation of enteric vapBC transcription: Induction by VapC toxin dimer-breaking
    • K.S. Winther, and K. Gerdes Regulation of enteric vapBC transcription: induction by VapC toxin dimer-breaking Nucleic Acids Res. 40 2012 4347 4357
    • (2012) Nucleic Acids Res. , vol.40 , pp. 4347-4357
    • Winther, K.S.1    Gerdes, K.2
  • 97
    • 84889590870 scopus 로고    scopus 로고
    • VapC20 of Mycobacterium tuberculosis cleaves the Sarcin-Ricin loop of 23S rRNA
    • K.S. Winther, D.E. Brodersen, A.K. Brown, and K. Gerdes VapC20 of Mycobacterium tuberculosis cleaves the Sarcin-Ricin loop of 23S rRNA Nat. Commun. 4 2013 2796
    • (2013) Nat. Commun. , vol.4 , pp. 2796
    • Winther, K.S.1    Brodersen, D.E.2    Brown, A.K.3    Gerdes, K.4
  • 98
    • 0025078793 scopus 로고
    • Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and beta-lactam antimicrobial agents
    • J.S. Wolfson, D.C. Hooper, G.L. McHugh, M.A. Bozza, and M.N. Swartz Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and beta-lactam antimicrobial agents Antimicrob. Agents Chemother. 34 1990 1938 1943
    • (1990) Antimicrob. Agents Chemother. , vol.34 , pp. 1938-1943
    • Wolfson, J.S.1    Hooper, D.C.2    McHugh, G.L.3    Bozza, M.A.4    Swartz, M.N.5
  • 100
    • 0041355231 scopus 로고    scopus 로고
    • Characterization of the interactions within the mazEF addiction module of Escherichia coli
    • J.J. Zhang, Y.L. Zhang, and M. Inouye Characterization of the interactions within the mazEF addiction module of Escherichia coli J. Biol. Chem. 278 2003 32300 32306
    • (2003) J. Biol. Chem. , vol.278 , pp. 32300-32306
    • Zhang, J.J.1    Zhang, Y.L.2    Inouye, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.