PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington’s disease (HD)

Cell Cycle

Volumn 14, Issue 11, 2015, Pages 1716-1729

  Ratovitski, Tamara ^a   Arbez, Nicolas ^a   Stewart, Jacqueline C ^a   Chighladze, Ekaterine ^a   Ross, Christopher A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene transcription; Huntingtin; Huntington s disease mechanism; Neurodegeneration; Protein interactions; Protein methylation; RNA processing

Indexed keywords

ARGININE; BRAIN DERIVED NEUROTROPHIC FACTOR; HISTONE H2A; HISTONE H4; HUNTINGTIN; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; SURVIVAL MOTOR NEURON PROTEIN; UNCLASSIFIED DRUG; DIMETHYLARGININE; HTT PROTEIN, HUMAN; NERVE PROTEIN; NUCLEAR PROTEIN; P80-COILIN; PRMT5 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CELL; COILED BODY; CONTROLLED STUDY; CORPUS STRIATUM; EMBRYO; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; IN VITRO STUDY; MOUSE; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PATHOGENESIS; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METHYLATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; RNA PROCESSING; RNA SPLICING; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; PHYSIOLOGY; RAT; WESTERN BLOTTING;

ANIMALS; ARGININE; BLOTTING, WESTERN; BRAIN; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; MICE; MICROSCOPY, FLUORESCENCE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEIN-ARGININE N-METHYLTRANSFERASES; RATS;

EID: 84929635972     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1033595     Document Type: Article

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