Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing

Journal of Cell Biology

Volumn 159, Issue 6, 2002, Pages 957-969

  Boisvert, François Michel ^a   Côté, Jocelyn ^a   Boulanger, Marie Chloé ^a   Cléroux, Patrick ^a   Bachand, Francßois ^a,b   Autexier, Chantal ^a,b   Richard, Stéphane ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Arginine methylation; Cajal; PRMT5; SMN; Splicing

Indexed keywords

5' METHYLTHIOADENOSINE; ANTIBODY; BINDING PROTEIN; CELL PROTEIN; COILIN; DIMETHYLATED ARGININE BINDING PROTEIN; EPITOPE; MESSENGER RNA; METHYL GROUP; POLYPEPTIDE; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; COILED BODY; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METHYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN LOCALIZATION; RNA SPLICING; SPINAL MUSCULAR ATROPHY; SPLICEOSOME;

ANTIBODIES; ARGININE; CELL NUCLEUS; COILED BODIES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HELA CELLS; HUMANS; MASS SPECTROMETRY; METHYLATION; MICROSCOPY, FLUORESCENCE; MUSCULAR ATROPHY, SPINAL; PRECIPITIN TESTS; RNA SPLICING; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION;

EID: 0037164866     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200207028     Document Type: Article

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