Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases

Toxicology in Vitro

Volumn 29, Issue 5, 2015, Pages 1146-1155

  Engstrom, Anna ^a   Wang, Hao ^a   Xia, Zhengui ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Adult neurogenesis; Apoptosis; Differentiation; Lead; Neurotoxicity; Proliferation

Indexed keywords

LEAD; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

ADULT; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; COGNITION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; HIPPOCAMPUS; IN VITRO STUDY; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIMARY CULTURE; SIGNAL TRANSDUCTION; SUBGRANULAR ZONE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DENTATE GYRUS; DRUG EFFECTS; METABOLISM;

MUS;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DENTATE GYRUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEAD; MALE; MICE, INBRED C57BL; NEURAL STEM CELLS; NEUROGENESIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 84929576130     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.05.001     Document Type: Article

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