Perinatal exposure to lead induces morphological, ultrastructural and molecular alterations in the hippocampus

Toxicology

Volumn 303, Issue , 2013, Pages 187-200

  Baranowska Bosiacka, I ^a   Struzynska L ^b   Gutowska, I ^c   Machalinska A ^a   Kolasa, A ^a   Klos P ^a   Czapski, G A ^b   Kurzawski, M ^a   Prokopowicz, A ^d   Marchlewicz, M ^a   Safranow, K ^a   Machalinski B ^a   Wiszniewska, B ^a   Chlubek, D ^a  

^a POMERANIAN MEDICAL UNIVERSITY   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c Department of Biochemistry and Human Nutrition ^*  (Poland)

^d INSTITUTE OF OCCUPATIONAL MEDICINE AND ENVIRONMENTAL HEALTH   (Poland)

Author keywords

AIF; Apoptosis; BDNF; Cell ultrastructure; Hippocampus; Lead neurotoxicity

Indexed keywords

APOPTOSIS INDUCING FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 3; DISTILLED WATER; DNA FRAGMENT; DRINKING WATER; LEAD ACETATE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BLOOD SAMPLING; BRAIN DEVELOPMENT; BRAIN REGION; CELL NUCLEUS; CELL ULTRASTRUCTURE; CEREBELLUM; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG BLOOD LEVEL; ENZYME ACTIVITY; FEEDING; FEMALE; FOREBRAIN; GENE TRANSLOCATION; HIPPOCAMPUS; MALE; MICROSCOPY; MOTHER; NECROPTOSIS; NERVE CELL; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; WEANING; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CEREBELLUM; CEREBRAL CORTEX; COGNITION DISORDERS; DNA FRAGMENTATION; FEMALE; HIPPOCAMPUS; MALE; NECROSIS; NEURONS; NEUROTOXICITY SYNDROMES; ORGANOMETALLIC COMPOUNDS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR;

RATTUS;

EID: 84871451729     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.10.027     Document Type: Article

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