Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23306-23317

  Pan, Yung Wei ^a   Zou, Junhui ^a   Wang, Wenbin ^a   Sakagami, Hiroyuki ^c   Garelick, Michael G ^b   Abel, Glen ^a   Kuo, Chay T ^d   Storm, Daniel R ^b   Xia, Zhengui ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT MICE; ADULT NEUROGENESIS; DENTATE GYRUS; EXTRACELLULAR SIGNAL-REGULATED KINASE; HIPPOCAMPAL NEUROGENESIS; IN-VIVO; MEMORY FORMATION; MITOGEN ACTIVATED PROTEIN KINASE; MOUSE BRAIN; NEURAL PROGENITOR CELLS; NEUROGENESIS; NEURONAL DIFFERENTIATION; NEUROTROPHINS; SIGNALING MECHANISMS;

CHEMICAL ACTIVATION; ENZYME ACTIVITY; MAMMALS; NEURONS; STEM CELLS; TRANSCRIPTION FACTORS;

BRAIN;

MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE 5; NEUROGENIN 2; NEUROTROPHIN 3; SHORT HAIRPIN RNA;

ADULT ANIMAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; HIPPOCAMPUS; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DENTATE GYRUS; HIPPOCAMPUS; LUMINESCENT PROTEINS; MALE; MAP KINASE KINASE 5; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MITOGEN-ACTIVATED PROTEIN KINASE 7; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NIH 3T3 CELLS; RNA INTERFERENCE; TAMOXIFEN;

EID: 84863623155     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.344762     Document Type: Article

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