Regulation of oligomeric organization of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor observed by spatial intensity distribution analysis

Journal of Biological Chemistry

Volumn 290, Issue 20, 2015, Pages 12844-12857

  Ward, Richard J ^a   Pediani, John D ^a   Godin, Antoine G ^b,c   Milligan, Graeme ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; DIMERS; IMAGE ENHANCEMENT; LIGANDS; MONOMERS; PROTEINS; SPATIAL DISTRIBUTION;

ENHANCED GREEN FLUORESCENT PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL GROWTH FACTORS; G PROTEIN COUPLED RECEPTORS; LASER SCANNING CONFOCAL MICROSCOPES; RECEPTOR ANTAGONISTS; SPATIAL INTENSITY DISTRIBUTION; TIME-DEPENDENT CHANGES;

SPATIAL VARIABLES MEASUREMENT;

DIMER; ENHANCED GREEN FLUORESCENT PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MONOMER; OLIGOMER; SEROTONIN 2C RECEPTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MULTIPROTEIN COMPLEX; SEROTONIN 2 ANTAGONIST;

ANALYTICAL PARAMETERS; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MYRISTYLATION; OLIGOMERIZATION; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; REGULATORY MECHANISM; SPATIAL INTENSITY DISTRIBUTION ANALYSIS; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN MULTIMERIZATION;

GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; MULTIPROTEIN COMPLEXES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RECEPTOR, SEROTONIN, 5-HT2C; RECOMBINANT FUSION PROTEINS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS;

EID: 84929377388     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.644724     Document Type: Article

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