-
1
-
-
0036174608
-
Dimerization: An emerging concept for G protein-coupled receptor ontogeny and function
-
Angers S, Salahpour A, and Bouvier M (2002) Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annu Rev Pharmacol Toxicol 42: 409-435.
-
(2002)
Annu Rev Pharmacol Toxicol
, vol.42
, pp. 409-435
-
-
Angers, S.1
Salahpour, A.2
Bouvier, M.3
-
2
-
-
0030736417
-
A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation
-
Barak LS, Ferguson SS, Zhang J, and Caron MG (1997a) A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. J Biol Chem 272: 27497-27500.
-
(1997)
J Biol Chem
, vol.272
, pp. 27497-27500
-
-
Barak, L.S.1
Ferguson, S.S.2
Zhang, J.3
Caron, M.G.4
-
3
-
-
0031025764
-
Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate
-
Barak LS, Ferguson SS, Zhang J, Martenson C, Meyer T, and Caron MG (1997b) Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate. Mol Pharmacol 51: 177-184.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 177-184
-
-
Barak, L.S.1
Ferguson, S.S.2
Zhang, J.3
Martenson, C.4
Meyer, T.5
Caron, M.G.6
-
4
-
-
78651390998
-
Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding
-
Bayburt TH, Vishnivetskiy SA, McLean MA, Morizumi T, Huang CC, Tesmer JJ, Ernst OP, Sligar SG, and Gurevich VV (2011) Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding. J Biol Chem 286: 1420-1428.
-
(2011)
J Biol Chem
, vol.286
, pp. 1420-1428
-
-
Bayburt, T.H.1
Vishnivetskiy, S.A.2
McLean, M.A.3
Morizumi, T.4
Huang, C.C.5
Tesmer, J.J.6
Ernst, O.P.7
Sligar, S.G.8
Gurevich, V.V.9
-
5
-
-
33845923854
-
BRET analysis of GPCR oligomerization: Newer does not mean better
-
author reply 4
-
Bouvier M, Heveker N, Jockers R, Marullo S, and Milligan G (2007) BRET analysis of GPCR oligomerization: newer does not mean better. Nat Methods 4:3-4, author reply 4.
-
(2007)
Nat Methods
, vol.4
, pp. 3-4
-
-
Bouvier, M.1
Heveker, N.2
Jockers, R.3
Marullo, S.4
Milligan, G.5
-
6
-
-
84872195772
-
Single-molecule analysis of fluorescently labeled G-proteincoupled receptors reveals complexes with distinct dynamics and organization
-
Calebiro D, Rieken F, Wagner J, Sungkaworn T, Zabel U, Borzi A, Cocucci E, Zürn A, and Lohse MJ (2013) Single-molecule analysis of fluorescently labeled G-proteincoupled receptors reveals complexes with distinct dynamics and organization. Proc Natl Acad Sci USA 110: 743-748.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 743-748
-
-
Calebiro, D.1
Rieken, F.2
Wagner, J.3
Sungkaworn, T.4
Zabel, U.5
Borzi, A.6
Cocucci, E.7
Zürn, A.8
Lohse, M.J.9
-
7
-
-
0033575916
-
A kinaseregulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor
-
Cao TT, Deacon HW, Reczek D, Bretscher A, and von Zastrow M (1999) A kinaseregulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature 401: 286-290.
-
(1999)
Nature
, vol.401
, pp. 286-290
-
-
Cao, T.T.1
Deacon, H.W.2
Reczek, D.3
Bretscher, A.4
Von Zastrow, M.5
-
8
-
-
61449236177
-
Analysis of receptor oligomerization by FRAP microscopy
-
Dorsch S, Klotz KN, Engelhardt S, Lohse MJ, and Bünemann M (2009) Analysis of receptor oligomerization by FRAP microscopy. Nat Methods 6: 225-230.
-
(2009)
Nat Methods
, vol.6
, pp. 225-230
-
-
Dorsch, S.1
Klotz, K.N.2
Engelhardt, S.3
Lohse, M.J.4
Bünemann, M.5
-
10
-
-
66849132354
-
Instability of a class a G protein-coupled receptor oligomer interface
-
Fonseca JM and Lambert NA (2009) Instability of a class a G protein-coupled receptor oligomer interface. Mol Pharmacol 75: 1296-1299.
-
(2009)
Mol Pharmacol
, vol.75
, pp. 1296-1299
-
-
Fonseca, J.M.1
Lambert, N.A.2
-
11
-
-
0029770657
-
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
-
Goodman OB, Jr, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, and Benovic JL (1996) Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature 383: 447-450.
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman Jr., O.B.1
Krupnick, J.G.2
Santini, F.3
Gurevich, V.V.4
Penn, R.B.5
Gagnon, A.W.6
Keen, J.H.7
Benovic, J.L.8
-
12
-
-
69249158290
-
Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation
-
Han Y, Moreira IS, Urizar E, Weinstein H, and Javitch JA (2009) Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation. Nat Chem Biol 5: 688-695.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 688-695
-
-
Han, Y.1
Moreira, I.S.2
Urizar, E.3
Weinstein, H.4
Javitch, J.A.5
-
13
-
-
33847607436
-
Each rhodopsin molecule binds its own arrestin
-
Hanson SM, Gurevich EV, Vishnivetskiy SA, Ahmed MR, Song X, and Gurevich VV (2007) Each rhodopsin molecule binds its own arrestin. Proc Natl Acad Sci USA 104: 3125-3128.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3125-3128
-
-
Hanson, S.M.1
Gurevich, E.V.2
Vishnivetskiy, S.A.3
Ahmed, M.R.4
Song, X.5
Gurevich, V.V.6
-
14
-
-
41149090339
-
Regulation of GPCRs by endocytic membrane trafficking and its potential implications
-
Hanyaloglu AC and von Zastrow M (2008) Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol 48: 537-568.
-
(2008)
Annu Rev Pharmacol Toxicol
, vol.48
, pp. 537-568
-
-
Hanyaloglu, A.C.1
Von Zastrow, M.2
-
15
-
-
0029666267
-
A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation
-
Hebert TE, Moffett S, Morello JP, Loisel TP, Bichet DG, Barret C, and Bouvier M (1996) A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. J Biol Chem 271: 16384-16392.
-
(1996)
J Biol Chem
, vol.271
, pp. 16384-16392
-
-
Hebert, T.E.1
Moffett, S.2
Morello, J.P.3
Loisel, T.P.4
Bichet, D.G.5
Barret, C.6
Bouvier, M.7
-
16
-
-
79960590320
-
Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments
-
Hong H and Bowie JU (2011) Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments. J Am Chem Soc 133: 11389-11398.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 11389-11398
-
-
Hong, H.1
Bowie, J.U.2
-
17
-
-
84875604499
-
Conformational biosensors reveal GPCR signalling from endosomes
-
Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, and Huang B et al. (2013) Conformational biosensors reveal GPCR signalling from endosomes. Nature 495: 534-538.
-
(2013)
Nature
, vol.495
, pp. 534-538
-
-
Irannejad, R.1
Tomshine, J.C.2
Tomshine, J.R.3
Chevalier, M.4
Mahoney, J.P.5
Steyaert, J.6
Rasmussen, S.G.7
Sunahara, R.K.8
El-Samad, H.9
Huang, B.10
-
18
-
-
33751215258
-
A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer
-
James JR, Oliveira MI, Carmo AM, Iaboni A, and Davis SJ (2006) A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer. Nat Methods 3: 1001-1006.
-
(2006)
Nat Methods
, vol.3
, pp. 1001-1006
-
-
James, J.R.1
Oliveira, M.I.2
Carmo, A.M.3
Iaboni, A.4
Davis, S.J.5
-
19
-
-
84873033099
-
B-Arrestins and G protein-coupled receptor trafficking
-
Kang DS, Tian X, and Benovic JL (2013) b-Arrestins and G protein-coupled receptor trafficking. Methods Enzymol 521: 91-108.
-
(2013)
Methods Enzymol
, vol.521
, pp. 91-108
-
-
Kang, D.S.1
Tian, X.2
Benovic, J.L.3
-
20
-
-
84862777498
-
Crystal structure of the channelrhodopsin light-gated cation channel
-
Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, and Hayashi S et al. (2012) Crystal structure of the channelrhodopsin light-gated cation channel. Nature 482: 369-374.
-
(2012)
Nature
, vol.482
, pp. 369-374
-
-
Kato, H.E.1
Zhang, F.2
Yizhar, O.3
Ramakrishnan, C.4
Nishizawa, T.5
Hirata, K.6
Ito, J.7
Aita, Y.8
Tsukazaki, T.9
Hayashi, S.10
-
21
-
-
84875430188
-
Stoichiometric analysis of oligomerization of membrane proteins on living cells using coiled-coil labeling and spectral imaging
-
Kawano K, Yano Y, Omae K, Matsuzaki S, and Matsuzaki K (2013) Stoichiometric analysis of oligomerization of membrane proteins on living cells using coiled-coil labeling and spectral imaging. Anal Chem 85: 3454-3461.
-
(2013)
Anal Chem
, vol.85
, pp. 3454-3461
-
-
Kawano, K.1
Yano, Y.2
Omae, K.3
Matsuzaki, S.4
Matsuzaki, K.5
-
22
-
-
0037225952
-
A general method for the covalent labeling of fusion proteins with small molecules in vivo
-
Keppler A, Gendreizig S, Gronemeyer T, Pick H, Vogel H, and Johnsson K (2003) A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat Biotechnol 21: 86-89.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 86-89
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
Johnsson, K.6
-
23
-
-
79954425389
-
Structural insights into adrenergic receptor function and pharmacology
-
Kobilka BK (2011) Structural insights into adrenergic receptor function and pharmacology. Trends Pharmacol Sci 32: 213-218.
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 213-218
-
-
Kobilka, B.K.1
-
24
-
-
79952046779
-
Internalization dissociates b2-adrenergic receptors
-
Lan TH, Kuravi S, and Lambert NA (2011) Internalization dissociates b2-adrenergic receptors. PLoS ONE 6:e17361.
-
(2011)
PLoS ONE
, vol.6
-
-
Lan, T.H.1
Kuravi, S.2
Lambert, N.A.3
-
25
-
-
33845245946
-
Rapid activation of inwardly rectifying potassium channels by immobile G-protein-coupled receptors
-
Lober RM, Pereira MA, and Lambert NA (2006) Rapid activation of inwardly rectifying potassium channels by immobile G-protein-coupled receptors. J Neurosci 26: 12602-12608.
-
(2006)
J Neurosci
, vol.26
, pp. 12602-12608
-
-
Lober, R.M.1
Pereira, M.A.2
Lambert, N.A.3
-
26
-
-
84860246622
-
FRET in membrane biophysics: An overview
-
Loura LM and Prieto M (2011) FRET in Membrane Biophysics: An Overview. Front Physiol 2:82.
-
(2011)
Front Physiol
, vol.2
, pp. 82
-
-
Loura, L.M.1
Prieto, M.2
-
27
-
-
84861096654
-
Crystal structure of the m-opioid receptor bound to a morphinan antagonist
-
Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, and Granier S (2012) Crystal structure of the m-opioid receptor bound to a morphinan antagonist. Nature 485: 321-326.
-
(2012)
Nature
, vol.485
, pp. 321-326
-
-
Manglik, A.1
Kruse, A.C.2
Kobilka, T.S.3
Thian, F.S.4
Mathiesen, J.M.5
Sunahara, R.K.6
Pardo, L.7
Weis, W.I.8
Kobilka, B.K.9
Granier, S.10
-
28
-
-
0037160105
-
Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer
-
Mercier JF, Salahpour A, Angers S, Breit A, and Bouvier M (2002) Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. J Biol Chem 277: 44925-44931.
-
(2002)
J Biol Chem
, vol.277
, pp. 44925-44931
-
-
Mercier, J.F.1
Salahpour, A.2
Angers, S.3
Breit, A.4
Bouvier, M.5
-
29
-
-
40349085622
-
A day in the life of a G protein-coupled receptor: The contribution to function of G protein-coupled receptor dimerization
-
Milligan G (2008) A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization. Br J Pharmacol 153 Suppl 1: S216-229.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Milligan, G.1
-
30
-
-
72449193715
-
The role of dimerisation in the cellular trafficking of G-proteincoupled receptors
-
Milligan G (2010) The role of dimerisation in the cellular trafficking of G-proteincoupled receptors. Curr Opin Pharmacol 10: 23-29.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 23-29
-
-
Milligan, G.1
-
31
-
-
21344433619
-
Methods to monitor the quaternary structure of G protein-coupled receptors
-
Milligan G and Bouvier M (2005) Methods to monitor the quaternary structure of G protein-coupled receptors. FEBS J 272: 2914-2925.
-
(2005)
FEBS J
, vol.272
, pp. 2914-2925
-
-
Milligan, G.1
Bouvier, M.2
-
32
-
-
0037020296
-
Functional immobilization of a ligand-activated G-protein-coupled receptor
-
Neumann L, Wohland T, Whelan RJ, Zare RN, and Kobilka BK (2002) Functional immobilization of a ligand-activated G-protein-coupled receptor. ChemBioChem 3: 993-998.
-
(2002)
ChemBioChem
, vol.3
, pp. 993-998
-
-
Neumann, L.1
Wohland, T.2
Whelan, R.J.3
Zare, R.N.4
Kobilka, B.K.5
-
33
-
-
78049281844
-
Oligomeric forms of G protein-coupled receptors (GPCRs)
-
Palczewski K (2010) Oligomeric forms of G protein-coupled receptors (GPCRs). Trends Biochem Sci 35: 595-600.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 595-600
-
-
Palczewski, K.1
-
35
-
-
0038662595
-
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors
-
Pin JP, Galvez T, and Prézeau L (2003) Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors. Pharmacol Ther 98: 325-354.
-
(2003)
Pharmacol Ther
, vol.98
, pp. 325-354
-
-
Pin, J.P.1
Galvez, T.2
Prézeau, L.3
-
36
-
-
78651411166
-
Structure of a nanobodystabilized active state of the b(2) adrenoceptor
-
Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, and Kobilka TS et al. (2011a) Structure of a nanobodystabilized active state of the b(2) adrenoceptor. Nature 469: 175-180.
-
(2011)
Nature
, vol.469
, pp. 175-180
-
-
Rasmussen, S.G.1
Choi, H.J.2
Fung, J.J.3
Pardon, E.4
Casarosa, P.5
Chae, P.S.6
Devree, B.T.7
Rosenbaum, D.M.8
Thian, F.S.9
Kobilka, T.S.10
-
37
-
-
80051658642
-
Crystal structure of the b2 adrenergic receptor-Gs protein complex
-
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, and Calinski D et al. (2011b) Crystal structure of the b2 adrenergic receptor-Gs protein complex. Nature 477: 549-555.
-
(2011)
Nature
, vol.477
, pp. 549-555
-
-
Rasmussen, S.G.1
Devree, B.T.2
Zou, Y.3
Kruse, A.C.4
Chung, K.Y.5
Kobilka, T.S.6
Thian, F.S.7
Chae, P.S.8
Pardon, E.9
Calinski, D.10
-
38
-
-
66249144426
-
The structure and function of G-protein-coupled receptors
-
Rosenbaum DM, Rasmussen SG, and Kobilka BK (2009) The structure and function of G-protein-coupled receptors. Nature 459: 356-363.
-
(2009)
Nature
, vol.459
, pp. 356-363
-
-
Rosenbaum, D.M.1
Rasmussen, S.G.2
Kobilka, B.K.3
-
39
-
-
4043125390
-
Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting
-
Salahpour A, Angers S, Mercier JF, Lagacé M, Marullo S, and Bouvier M (2004) Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J Biol Chem 279: 33390-33397.
-
(2004)
J Biol Chem
, vol.279
, pp. 33390-33397
-
-
Salahpour, A.1
Angers, S.2
Mercier, J.F.3
Lagacé, M.4
Marullo, S.5
Bouvier, M.6
-
40
-
-
34547636173
-
Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization
-
author reply 601
-
Salahpour A and Masri B (2007) Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization. Nat Methods 4:599-600, author reply 601.
-
(2007)
Nat Methods
, vol.4
, pp. 599-600
-
-
Salahpour, A.1
Masri, B.2
-
41
-
-
80051695489
-
Confinement of b(1)- and b(2)-adrenergic receptors in the plasma membrane of cardiomyocyte-like H9c2 cells is mediated by selective interactions with PDZ domain and A-kinase anchoring proteins but not caveolae
-
Valentine CD and Haggie PM (2011) Confinement of b(1)- and b(2)-adrenergic receptors in the plasma membrane of cardiomyocyte-like H9c2 cells is mediated by selective interactions with PDZ domain and A-kinase anchoring proteins but not caveolae. Mol Biol Cell 22: 2970-2982.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 2970-2982
-
-
Valentine, C.D.1
Haggie, P.M.2
-
43
-
-
34250666273
-
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
-
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, and Sunahara RK (2007) A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci USA 104: 7682-7687.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7682-7687
-
-
Whorton, M.R.1
Bokoch, M.P.2
Rasmussen, S.G.3
Huang, B.4
Zare, R.N.5
Kobilka, B.6
Sunahara, R.K.7
-
44
-
-
42949164679
-
Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer
-
Whorton MR, Jastrzebska B, Park PS, Fotiadis D, Engel A, Palczewski K, and Sunahara RK (2008) Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. J Biol Chem 283: 4387-4394.
-
(2008)
J Biol Chem
, vol.283
, pp. 4387-4394
-
-
Whorton, M.R.1
Jastrzebska, B.2
Park, P.S.3
Fotiadis, D.4
Engel, A.5
Palczewski, K.6
Sunahara, R.K.7
|