Probing homodimer formation of epidermal growth factor receptor by selective crosslinking

European Journal of Medicinal Chemistry

Volumn 88, Issue , 2014, Pages 34-41

  Sun, Xiaoli ^a,b   Dusserre Bresson, Florence ^a   Baker, Brenda ^a   Zhang, Aihua ^a   Xu, Patrick ^a   Fibbe, Cassandra ^a   Noren, Christopher J ^a   Corrêa, Ivan R ^a   Xu, Ming Qun ^a  

^a NEW ENGLAND BIOLABS   (United States)

^b FUDAN UNIVERSITY   (China)

Author keywords

Phosphorylation; Receptor tyrosine kinase; S CROSS; SNAP tag

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HOMODIMER; PROTEIN; SNAP PROTEIN; UNCLASSIFIED DRUG; CROSS-LINKING REAGENTS; LIGANDS; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMALL MOLECULE LIBRARIES;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CELL GROWTH; CELL MEMBRANE; CELL STIMULATION; CONFORMATIONAL TRANSITION; CROSS LINKING; DIMERIZATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; LIGAND BINDING; PROTEIN ANALYSIS; RECEPTOR BINDING; SELECTIVE CROSSLINKING; UPREGULATION; WILD TYPE; ANTAGONISTS AND INHIBITORS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HEK293 CELLS; HUMANS; METABOLISM; MOLECULAR STRUCTURE; PHARMACOLOGY; PROTEIN MULTIMERIZATION; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CROSS-LINKING REAGENTS; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HEK293 CELLS; HUMANS; LIGANDS; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEIN MULTIMERIZATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84911460551     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.07.041     Document Type: Article

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