Formulation of solid self-nanoemulsifying drug delivery systems using N-methyl pyrrolidone as cosolvent

Drug Development and Industrial Pharmacy

Volumn 41, Issue 4, 2015, Pages 594-604

  Agrawal, Anuj G ^a   Kumar, Ashok ^a   Gide, Paraag S ^b  

^a Cachet Pharmaceuticals Pvt Ltd   (India)

^b Dr L H Hiranandani College of Pharmacy   (India)

Author keywords

Atorvastatin calcium; Bioavailability; Emulsion; Oral drug delivery; Permeability; SNEDDS; Solubility; Surfactant

Indexed keywords

1 METHYL 2 PYRROLIDINONE; AEROSIL; ATORVASTATIN; CREMOPHOR; POLYSORBATE 20; POLYSORBATE 80; 2 PYRROLIDONE DERIVATIVE; DRUG VEHICLE; EMULSION; GLYCEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; N-METHYLPYRROLIDONE; NANOMATERIAL; POLYSORBATE;

APPARENT PERMEABILITY; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; EX VIVO STUDY; IN VITRO STUDY; INFRARED SPECTROSCOPY; NANOEMULSION; PH; PHASE SEPARATION; PRECIPITATION; REFRACTION INDEX; SCANNING ELECTRON MICROSCOPY; SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM; TRANSMISSION ELECTRON MICROSCOPY; VISCOSITY; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DRUG RELEASE; EMULSION; GOAT; INTESTINE ABSORPTION; INTESTINE MUCOSA; METABOLISM; PARTICLE SIZE; PHASE TRANSITION; SLAUGHTERHOUSE; SMALL INTESTINE; ULTRASTRUCTURE;

ABATTOIRS; ANIMALS; ATORVASTATIN CALCIUM; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; DRUG STABILITY; EMULSIONS; GLYCEROL; GOATS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINE, SMALL; NANOSTRUCTURES; PARTICLE SIZE; PHARMACEUTICAL VEHICLES; PHASE TRANSITION; POLYSORBATES; PYRROLIDINONES;

EID: 84929089524     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2014.886695     Document Type: Article

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